Twins vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Sep 19

min read
Cleveland Guardians' Myles Straw attempts to run to first after grounding out to Los Angeles Angels starting pitcher Kenny Rosenberg who threw to first baseman Mike Moustakas during the first inning of a baseball game, Sunday, Sept. 10, 2023, in Anaheim, Calif.
(AP Photo/Ryan Sun)
BetMGM Betting @BETMGM Sep 19, 2024, 11:01 AM
  • The Twins are -110 favorites vs the Guardians
  • Twins vs Guardians Over / Under today: 8.5 Runs
  • Twins / Guardians TV Channel: BSGL | BSNO | MLBN

The Minnesota Twins (-110) visit Progressive Field to take on the Cleveland Guardians (-110) on Thursday, September 19, 2024. First pitch is scheduled for 1:10pm EDT in Cleveland, OH.

This season, the Twins are 80-72 against the spread (ATS), while the Guardians are 77-76 ATS.

Twins vs Guardians Starting Pitchers Today:

  • Twins starting pitcher: Simeon Woods Richardson 5-5, 4.11 ERA
  • Guardians starting pitcher: Joey Cantillo 2-3, 5.16 ERA

Twins vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins-1.5 +155O 8 -115-110
Guardians +1.5 -190U 8 -105-110

Twins vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Thursday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Thursday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Simeon Woods Richard has hit the Walks Allowed Over in 15 of his last 19 games (+13.10 Units / 63% ROI)
  • Kyle Farmer has hit the Home Runs Over in 2 of his last 4 games (+12.60 Units / 315% ROI)
  • Royce Lewis has hit the Runs Under in 16 of his last 19 games (+11.60 Units / 43% ROI)
  • Royce Lewis has hit the Total Bases Under in 12 of his last 14 away games (+10.05 Units / 49% ROI)
  • Simeon Woods Richard has hit the Hits Allowed Under in 15 of his last 21 games (+10.00 Units / 42% ROI)

And here are some favorite MLB player prop bets for Guardians players for Thursday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Lane Thomas has hit the Home Runs Over in 5 of his last 15 games (+17.60 Units / 117% ROI)
  • Jose Ramirez has hit the RBIs Under in 18 of his last 21 games (+12.80 Units / 35% ROI)
  • Lane Thomas has hit the Hits Under in 14 of his last 23 games at home (+10.90 Units / 44% ROI)
  • Bo Naylor has hit the Hits Runs and RBIs Under in 10 of his last 11 games (+9.90 Units / 76% ROI)
  • Lane Thomas has hit the Total Bases Under in 17 of his last 24 games at home (+9.40 Units / 28% ROI)
  • The Minnesota Twins have hit the Game Total Over in 49 of their last 86 games (+14.10 Units / 15% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 21 away games (+7.95 Units / 28% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 15 of their last 26 away games (+4.15 Units / 13% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 9 of their last 14 away games (+3.70 Units / 22% ROI)
  • The Minnesota Twins have covered the Run Line in 5 of their last 8 games (+2.05 Units / 20% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 36 of their last 61 games (+12.80 Units / 19% ROI)
  • The Cleveland Guardians have hit the Moneyline in 88 of their last 153 games (+11.82 Units / 6% ROI)
  • The Cleveland Guardians have covered the Run Line in 35 of their last 71 games at home (+9.75 Units / 12% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in their last 6 games (+6.05 Units / 75% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 70-82 against the Run Line (-16.4 Units / -8.49% ROI).

  • 80-72 when betting on the Moneyline for -11.1 Units / -5.13% ROI
  • 77-66 when betting on the total runs Over for +4.7 Units / 2.83% ROI
  • 66-77 when betting on the total runs Under for -18.95 Units / -11.38% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 77-76 against the Run Line (+3.45 Units / 1.81% ROI).

  • 88-65 when betting on the Moneyline for +11.82 Units / 5.95% ROI
  • 68-75 when betting on the total runs Over for -14.95 Units / -8.84% ROI
  • 75-68 when betting on the total runs Under for +0.25 Units / 0.15% ROI

Guardians vs Twins Home Run Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +360 0.5 -500
Matt Wallner (MIN) 0.5 +475 0.5 -650
Jhonkensy Noel (CLE) 0.5 +475 0.5 -650
Kyle Manzardo (CLE) 0.5 +475 0.5 -650
Jose Ramirez (CLE) 0.5 +500 0.5 -700

Guardians vs Twins Total Hits Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 -250 0.5 +180
Manuel Margot (MIN) 0.5 -250 0.5 +185
Jose Ramirez (CLE) 0.5 -250 0.5 +190
Andres Gimenez (CLE) 0.5 -250 0.5 +180
Byron Buxton (MIN) 0.5 -200 0.5 +145

Guardians vs Twins RBI Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +155 0.5 -200
Josh Naylor (CLE) 0.5 +160 0.5 -210
Lane Thomas (CLE) 0.5 +165 0.5 -225
Jose Ramirez (CLE) 0.5 +165 0.5 -225
Carlos Santana (MIN) 0.5 +170 0.5 -225

Guardians vs Twins Strikeout Prop Bets Today

Over Under
Joey Cantillo (CLE) 4.5 -135 4.5 +105

Opponents have a groundball batting average of .412 (21 GB hits out of 51 GBs) against Simeon Woods Richardson with runners on base this season — 2nd highest in MLB among starting pitchers with at least 60 total IP; League Avg: .257 — first Percentile.

Hitters have chased just 52 of Simeon Woods Richardson’s 232 changeups out of the zone (chase rate of 22%) this season — lowest in MLB among starting pitchers with at least 60 total IP; League Avg: 35% — first Percentile.

The last hit on a Simeon Woods Richardson curveball was August 10th. Hitters are 0 for their last 18 in ABs ending on his curveball. — Caleb Thielbar has the longest active streak at 22.

Right-handed hitters have a groundball rate of just 34% (77/225) against Simeon Woods Richardson this season — 8th lowest in MLB among starting pitchers with at least 60 total IP; League Avg: 43% — sixth Percentile.

Guardians Starting Pitcher Stats & Trends

Joey Cantillo has allowed an OBP of just .125 (32 PA’s) against right-handed batters in his last two starts — best in MLB over the last two weeks; League Avg: .273 — 100th Percentile.

Opponents are hitting just .125 (5-for-40) against Joey Cantillo in his last two starts — tied for 6th best in MLB over the last two weeks; League Avg: .226 — 94th Percentile.

Joey Cantillo has not walked any of the 32 batters that he has faced against right-handed batters in his last two starts — tied for best in MLB over the last two weeks; League Avg: 6% — 100th Percentile.

Joey Cantillo has allowed an OPS of just .296 (41 PA’s) in his last two starts — 3rd best in MLB over the last two weeks; League Avg: .651 — 97th Percentile.

Twins Keys to the Game vs. the Guardians

The Twins are 138-2 (.986) when leading entering the 9th inning since the 2023 season — best in MLB; League Avg: .949.

The Twins are just 1-62 (.016) when trailing entering the 9th inning this season — 4th lowest in MLB; League Avg: .051.

The Twins are 26-103 (.202) when trailing entering the 7th inning since the 2023 season — tied for 2nd best in MLB; League Avg: .142.

The Twins are 62-26 (.705) when they’ve scored in the first inning since the 2023 season — 4th best in MLB; League Avg: .626.

Guardians Keys to the Game vs. the Twins

The Guardians are 24-29 (.453) when allowing 2 or more home runs this season — best in MLB; League Avg: .293.

The Guardians are 47-28 (.627) at home this season — 3rd best in MLB; League Avg: .524.

The Guardians are 73-2 (.973) when leading entering the 8th inning this season — best in MLB; League Avg: .899.

The Guardians are 78-0 (1.000) when leading entering the 9th inning this season — best in MLB; League Avg: .949.

Twins hitters have an OPS of .760 (3,757 PA’s) in innings 7-9 since last season — best in MLB; League Avg: .700.

Twins hitters have an OBP of .325 (8,910 PA’s) against RHP since last season — 4th best in MLB; League Avg: .316.

Twins hitters have an OBP of .331 (2,795 PA’s) at home this season — 4th best in MLB; League Avg: .316.

Twins hitters are slugging .621 on the first pitch of at-bats since last season — 5th best in MLB; League Avg: .578.

The Guardians are batting just .294 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .332.

Guardians hitters have put just 35% of balls in play to the left side of the field since the 2022 season — lowest in MLB; League Avg: 38%.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 38%.

The Guardians have barrels in 4% of PA’s since last season (442/11,736) — lowest in MLB; League Avg: 5%.

Twins pitchers have walked 392 of 5,639 batters (7%) this season — tied for 2nd best in MLB; League Avg: 8%.

Twins pitchers have a strikeout rate of 26% when facing the leadoff batter in the inning since last season — best in MLB; League Avg: 22%.

Opponents have a groundball rate of just 41% against Twins pitchers this season — tied for 3rd lowest in MLB; League Avg: 43%.

Twins pitchers have walked 182 of 2,805 batters (7%) when facing the leadoff batter in the inning since last season — 3rd best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .207 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .263.

Opponents have a groundball batting average of just .222 against Guardians pitchers this season — best in MLB; League Avg: .249.

Guardians pitchers have won 41% of games in which they have allowed their opponent to score in three different innings this season — highest in MLB; League Avg: 26%.

The Guardians have allowed 0.87 runs per game (133/153) in late innings this season — best in MLB; League Avg: 1.30.

Guardians vs. Twins Injuries Tonight That May Affect Prop Bets 

  • Cleveland Guardians – No Injuries Reported
  • Minnesota Twins – No Injuries Reported

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.