- The Astros are -175 favorites vs the White Sox
- White Sox vs Astros Over / Under today: 8.5 Runs
- White Sox / Astros TV Channel: SCHN | CHSN
The Chicago White Sox (+140) visit Daikin Park to take on the Houston Astros (-170) on Wednesday, June 11, 2025. First pitch is scheduled for 8:10pm EDT in Houston, TX.
This season, the White Sox are 23-44 against the spread (ATS), while the Astros are 35-31 ATS.
White Sox vs Astros Starting Pitchers Today:
- White Sox starting pitcher: Sean Burke 3-6, 4.12 ERA
- Astros starting pitcher: Ryan Gusto 3-3, 4.71 ERA
White Sox vs. Astros Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| White Sox | +1.5 -155 | O 8.5 -115 | +140 |
| Astros | -1.5 +125 | U 8.5 -105 | -170 |
White Sox vs Astros Prediction for Today’s Game
Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 61.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:
Best White Sox Player Prop Bets Today:
- Josh Rojas has hit the Singles Under in 21 of his last 25 games (+13.65 Units / 30% ROI)
- Chase Meidroth has hit the Total Bases Over in 19 of his last 25 games (+13.60 Units / 34% ROI)
- Chase Meidroth has hit the Hits Over in 21 of his last 25 games (+13.00 Units / 27% ROI)
- Chase Meidroth has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+11.90 Units / 45% ROI)
- Miguel Vargas has hit the Home Runs Over in 3 of his last 10 away games (+10.25 Units / 102% ROI)
And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:
Best Astros Player Prop Best Bets Today:
- Jeremy Pena has hit the Hits Over in 21 of his last 25 games at home (+23.50 Units / 55% ROI)
- Jeremy Pena has hit the Singles Over in 21 of his last 25 games at home (+15.55 Units / 46% ROI)
- Yainer Diaz has hit the Home Runs Over in 3 of his last 10 games (+11.40 Units / 114% ROI)
- Jeremy Pena has hit the Hits Runs and RBIs Over in 16 of his last 20 games at home (+10.85 Units / 40% ROI)
- Jeremy Pena has hit the Total Bases Over in 16 of his last 25 games at home (+10.25 Units / 39% ROI)
White Sox Best Bets Today:
- The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 30 of their last 44 games (+15.70 Units / 31% ROI)
- The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 19 of their last 43 games (+12.25 Units / 28% ROI)
- The Chicago White Sox have hit the Team Total Under in 22 of their last 32 away games (+11.50 Units / 31% ROI)
- The Chicago White Sox have covered the Run Line in 28 of their last 43 games (+11.10 Units / 22% ROI)
- The Chicago White Sox have hit the Game Total Under in 20 of their last 31 away games (+8.95 Units / 26% ROI)
Astros Best Bets Today:
- The Houston Astros have hit the Team Total Under in 40 of their last 66 games (+11.50 Units / 15% ROI)
- The Houston Astros have covered the Run Line in 33 of their last 58 games (+10.62 Units / 15% ROI)
- The Houston Astros have hit the Game Total Under in 22 of their last 33 games (+10.15 Units / 28% ROI)
- The Houston Astros have hit the Moneyline in 19 of their last 27 games at home (+9.10 Units / 25% ROI)
- The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 games at home (+8.65 Units / 24% ROI)
White Sox Against the Spread (ATS) Record
Against the spread this season, the White Sox are 39-28 against the Run Line (+7.9 Units / 9.92% ROI).
- 23-44 when betting on the Moneyline for -8.46 Units / -12.61% ROI
- 31-33 when betting on the total runs Over for -5.45 Units / -7.39% ROI
- 33-31 when betting on the total runs Under for -1.3 Units / -1.76% ROI
Astros Against the Spread (ATS) Record
Against the spread this season, the Astros are 35-31 against the Run Line (+5.97 Units / 7.18% ROI).
- 36-30 when betting on the Moneyline for -0.15 Units / -0.18% ROI
- 26-38 when betting on the total runs Over for -15.6 Units / -21.55% ROI
- 38-26 when betting on the total runs Under for +9.4 Units / 12.89% ROI
Astros vs White Sox Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Christian Walker (HOU) | 0.5 +310 | 0.5 -400 |
| Isaac Paredes (HOU) | 0.5 +400 | 0.5 -550 |
| Miguel Vargas (CWS) | 0.5 +425 | 0.5 -600 |
| Luis Robert (CWS) | 0.5 +450 | 0.5 -625 |
| Yainer Diaz (HOU) | 0.5 +475 | 0.5 -650 |
Astros vs White Sox Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Isaac Paredes (HOU) | 0.5 -220 | 0.5 +165 |
| Chase Meidroth (CWS) | 0.5 -210 | 0.5 +160 |
| Andrew Benintendi (CWS) | 0.5 -210 | 0.5 +155 |
| Jake Meyers (HOU) | 0.5 -210 | 0.5 +155 |
| Christian Walker (HOU) | 0.5 -200 | 0.5 +155 |
Astros vs White Sox RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Yainer Diaz (HOU) | 0.5 +130 | 0.5 -165 |
| Isaac Paredes (HOU) | 0.5 +140 | 0.5 -185 |
| Christian Walker (HOU) | 0.5 +140 | 0.5 -185 |
| Jeremy Pena (HOU) | 0.5 +145 | 0.5 -200 |
| Miguel Vargas (CWS) | 0.5 +155 | 0.5 -210 |
Astros vs White Sox Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Ryan Gusto (HOU) | 4.5 +105 | 4.5 -135 |
| Sean Burke (CWS) | 4.5 +125 | 4.5 -160 |
White Sox Starting Pitcher Stats & Trends
Sean Burke has walked 16% of left-handed batters this season — highest among qualified SPs in MLB; League Avg: 8% — first Percentile.
Sean Burke has struck out just 15% (23/151) of right-handed batters he faced this season — 6th lowest among qualified SPs in MLB; League Avg: 23% — seventh Percentile.
Sean Burke has a strikeout rate of just 14% (16 SO in 115 PAs) when going through the lineup the second time in a game this season — 8th lowest among qualified SPs in MLB; League Avg: 22% — 10th Percentile.
Sean Burke has thrown his fastball for a strike just 58% (305/521) of the time this season — lowest among qualified SPs in MLB*; League Avg: 67% — first Percentile.
Astros Starting Pitcher Stats & Trends
Ryan Gusto has allowed an OPS of .996 (102 PA’s) vs left-handed batters this season — 4th highest in MLB among starting pitchers with at least 26 total IP; League Avg: .726 — third Percentile.
Opponents have a groundball batting average of .354 (17 GB hits out of 48 GBs) against Ryan Gusto this season — 3rd highest in MLB among starting pitchers with at least 26 total IP; League Avg: .242 — first Percentile.
Opponents are hitting .432 (35-for-81) against Ryan Gusto in non-two strike counts this season — 4th highest in MLB among starting pitchers with at least 26 total IP; League Avg: .325 — second Percentile.
Ryan Gusto has allowed an OBP of .478 (23 PA’s) this month (1 game) — 6th highest in MLB among starting pitchers with at least 3 total IP; League Avg: .308 — fourth Percentile.
White Sox Keys to the Game vs. the Astros
The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.
The White Sox are just 24-87 (.216) on the road since last season — lowest in MLB; League Avg: .469.
The White Sox are just 52-28 (.650) when leading entering the 7th inning since last season — lowest in MLB; League Avg: .858.
The White Sox are just 63-163 (.279) since last season — lowest in MLB; League Avg: .500.
Astros Keys to the Game vs. the White Sox
The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.
The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.
The Astros are just 1-82 (.012) when trailing entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .048.
The Astros are 67-46 (.593) at home since last season — 5th best in MLB; League Avg: .530.
White Sox Hitting Stats & Trends
The White Sox have a winning percentage of just 22% on the road since last season — lowest in MLB; League Avg: 47%.
White Sox hitters have an OBP of just .215 (7,629 PA’s) with two-strikes since the 2023 season — lowest in MLB; League Avg: .247.
White Sox hitters have an OPS of just .645 (10,830 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .722.
White Sox hitters had an OBP of just .213 (3,148 PA’s) with two-strikes in 2023 — lowest in MLB; League Avg: .249.
Astros Hitting Stats & Trends
Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.
Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.
Astros hitters have put 43% of balls in play to the left side of the field since the 2023 season — highest in MLB; League Avg: 38%.
Astros hitters averaged just 3.66 pitches per plate appearance in the 2024 season — lowest in MLB; League Avg: 3.89.
White Sox Pitching Stats & Trends
The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 32%.
The White Sox have won just 12% of games in which their opponents scored first since last season — lowest in MLB; League Avg: 32%.
White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.
White Sox pitchers have walked 10% of batters since last season — highest in MLB; League Avg: 8%.
Astros Pitching Stats & Trends
Opponents have a miss rate of 29% against Astros pitchers this season — best in MLB; League Avg: 25%.
Astros pitchers have a strikeout rate of 27% this season — best in MLB; League Avg: 22%.
Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.
Astros pitchers have a strikeout rate of 46% with two-strikes since last season — tied for best in MLB; League Avg: 42%.
More MLB Reading:
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