White Sox vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Jun 12

Houston Astros' Yordan Alvarez runs up the first base line against the Los Angeles Angels during the fourth inning of a baseball game Sunday, June 4, 2023, in Houston.
(AP Photo/David J. Phillip)
  • The Astros are -225 favorites vs the White Sox
  • White Sox vs Astros Over / Under today: 7.5 Runs
  • White Sox / Astros TV Channel: SCHN | CHSN

The Chicago White Sox (+185) visit Daikin Park to take on the Houston Astros (-225) on Thursday, June 12, 2025. First pitch is scheduled for 8:10pm EDT in Houston, TX.

This season, the White Sox are 23-45 against the spread (ATS), while the Astros are 36-31 ATS.

White Sox vs Astros Starting Pitchers Today:

  • White Sox starting pitcher: Davis Martin 2-6, 3.64 ERA
  • Astros starting pitcher: Framber Valdez 6-4, 3.11 ERA

White Sox vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -120O 7.5 -120+185
Astros -1.5 +100U 7.5 +100-225

White Sox vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Thursday‘s MLB game with 67.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Thursday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Davis Martin has hit the Pitching Outs Over in his last 5 games (+5.40 Units / 102% ROI)
  • Davis Martin has hit the Walks Allowed Under in 6 of his last 7 games (+5.05 Units / 61% ROI)
  • Davis Martin has hit the Hits Allowed Under in his last 4 games (+4.25 Units / 92% ROI)
  • Davis Martin has hit the Earned Runs Under in 4 of his last 5 games (+3.20 Units / 59% ROI)
  • Davis Martin has hit the Strikeouts Under in 10 of his last 15 games (+3.10 Units / 15% ROI)

And here are some favorite MLB player prop bets for Astros players for Thursday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Jeremy Pena has hit the Hits Over in 21 of his last 25 games at home (+24.10 Units / 58% ROI)
  • Jeremy Pena has hit the Singles Over in 21 of his last 25 games at home (+15.55 Units / 45% ROI)
  • Jeremy Pena has hit the Hits Runs and RBIs Over in 19 of his last 25 games at home (+11.80 Units / 36% ROI)
  • Jeremy Pena has hit the Total Bases Over in 16 of his last 25 games at home (+10.25 Units / 41% ROI)
  • Isaac Paredes has hit the Home Runs Over in 2 of his last 8 games (+8.10 Units / 101% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 30 of their last 45 games (+14.35 Units / 28% ROI)
  • The Chicago White Sox have hit the Team Total Under in 23 of their last 33 away games (+12.50 Units / 33% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 19 of their last 44 games (+11.25 Units / 25% ROI)
  • The Chicago White Sox have covered the Run Line in 28 of their last 44 games (+9.60 Units / 18% ROI)
  • The Chicago White Sox have hit the Game Total Under in 20 of their last 32 away games (+7.95 Units / 23% ROI)
  • The Houston Astros have covered the Run Line in 34 of their last 59 games (+11.87 Units / 16% ROI)
  • The Houston Astros have hit the Team Total Under in 40 of their last 67 games (+10.25 Units / 13% ROI)
  • The Houston Astros have hit the Moneyline in 20 of their last 28 games at home (+10.10 Units / 27% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 31 games at home (+9.85 Units / 26% ROI)
  • The Houston Astros have hit the Game Total Under in 22 of their last 34 games (+9.15 Units / 25% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 39-29 against the Run Line (+6.4 Units / 7.89% ROI).

  • 23-45 when betting on the Moneyline for -9.46 Units / -13.89% ROI
  • 32-33 when betting on the total runs Over for -4.45 Units / -5.94% ROI
  • 33-32 when betting on the total runs Under for -2.3 Units / -3.08% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 36-31 against the Run Line (+7.22 Units / 8.59% ROI).

  • 37-30 when betting on the Moneyline for +0.85 Units / 0.98% ROI
  • 27-38 when betting on the total runs Over for -14.6 Units / -19.84% ROI
  • 38-27 when betting on the total runs Under for +8.4 Units / 11.37% ROI

Astros vs White Sox Home Run Prop Bets Today

Over Under
Christian Walker (HOU) 0.5 +375 0.5 -525
Isaac Paredes (HOU) 0.5 +475 0.5 -650
Yainer Diaz (HOU) 0.5 +525 0.5 -750
Jeremy Pena (HOU) 0.5 +600 0.5 -1000
Miguel Vargas (CWS) 0.5 +675 0.5 -1100

Astros vs White Sox Total Hits Prop Bets Today

Over Under
Jose Altuve (HOU) 0.5 -250 0.5 +190
Jake Meyers (HOU) 0.5 -210 0.5 +155
Isaac Paredes (HOU) 0.5 -210 0.5 +160
Christian Walker (HOU) 0.5 -210 0.5 +160
Victor Caratini (HOU) 0.5 -200 0.5 +150

Astros vs White Sox RBI Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 +135 0.5 -175
Isaac Paredes (HOU) 0.5 +150 0.5 -200
Christian Walker (HOU) 0.5 +155 0.5 -210
Jeremy Pena (HOU) 0.5 +170 0.5 -220
Jose Altuve (HOU) 0.5 +185 0.5 -250

Astros vs White Sox Strikeout Prop Bets Today

Over Under
Davis Martin (CWS) 3.5 -150 3.5 +115
Framber Valdez (HOU) 7.5 +120 7.5 -155

Davis Martin has struck out just 13% (17/132) of left-handed batters he faced this season — 2nd lowest among qualified SPs in MLB; League Avg: 22% — third Percentile.

Davis Martin has a strikeout rate of just 15% (18 SO in 117 PAs) when going through the lineup the first time in a game this season — tied for 6th lowest among qualified SPs in MLB; League Avg: 24% — eighth Percentile.

Davis Martin has a strikeout rate of just 16% (48 SO in 307 PAs) this season — tied for 9th lowest among qualified SPs in MLB; League Avg: 22% — 12th Percentile.

Left-handed hitters have a groundball rate of 52% (54/104) against Davis Martin this season — 8th highest among qualified SPs in MLB; League Avg: 43% — 86th Percentile.

Astros Starting Pitcher Stats & Trends

Opponents had a groundball rate of 61% (291/473) against Framber Valdez in the 2024 season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Opponents have a groundball rate of 61% (423/694) against Framber Valdez since last season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Framber Valdez located 41% of his pitches inside (1,071/2,598) in the 2024 season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

Framber Valdez located 42% of his pitches inside (302/710) with two-strikes in the 2024 season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

White Sox Keys to the Game vs. the Astros

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox are just 40-123 (.245) after a loss since last season — lowest in MLB; League Avg: .500.

The White Sox were just 18-63 (.222) on the road in the 2024 season — lowest in MLB; League Avg: .478.

Astros Keys to the Game vs. the White Sox

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are 166-18 (.902) when leading entering the 7th inning since the 2023 season — 4th best in MLB; League Avg: .859.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

The Astros are 67-46 (.593) at home since last season — 5th best in MLB; League Avg: .530.

White Sox hitters have an OBP of just .286 (10,855 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .316.

White Sox hitters have an OPS of just .645 (10,855 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .722.

White Sox hitters have an OPS of just .627 (6,259 PA’s) against RHP since last season — lowest in MLB; League Avg: .715.

White Sox hitters have an OBP of just .287 (14,333 PA’s) since the 2023 season — lowest in MLB; League Avg: .316.

Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.

Astros hitters are averaging just 3.73 pitches per plate appearance against RHP since the 2023 season — lowest in MLB; League Avg: 3.89.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters are averaging just 3.68 pitches per plate appearance against RHP since last season — lowest in MLB; League Avg: 3.89.

The White Sox have won just 12% of games in which their opponents scored first since last season — lowest in MLB; League Avg: 32%.

White Sox pitchers have won only 12% of games in which they have allowed their opponent to score in three different innings since the 2023 season — lowest in MLB; League Avg: 27%.

In games when their opponents have scored three or more runs in an inning, the White Sox won just 5% of the time since last season — lowest in MLB; League Avg: 24%.

The White Sox have won just 6% of road games in which their opponents scored first since last season — lowest in MLB; League Avg: 26%.

Opponents have a miss rate of 29% against Astros pitchers this season — best in MLB; League Avg: 25%.

Astros pitchers have a strikeout rate of 33% over the past seven days (6 games) — best in MLB; League Avg: 22%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Opponents had a miss rate of 27% against Astros pitchers in the 2024 season — 2nd best in MLB; League Avg: 25%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.