White Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Apr 9

(AP Photo/Ryan Sun)
  • The Guardians are -190 favorites vs the White Sox
  • White Sox vs Guardians Over / Under today: 7.5 Runs
  • White Sox / Guardians TV Channel: GDTV | CHS+

The Chicago White Sox (+155) visit Progressive Field to take on the Cleveland Guardians (-190) on Wednesday, April 9, 2025. First pitch is scheduled for 6:10pm EDT in Cleveland, OH.

This season, the White Sox are 2-8 against the spread (ATS), while the Guardians are 4-6 ATS.

White Sox vs Guardians Starting Pitchers Today:

  • White Sox starting pitcher: Sean Burke 1-1, 5.23 ERA
  • Guardians starting pitcher: Logan Allen 0-1, 7.20 ERA

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -145O 7.5 -118+155
Guardians -1.5 +118U 7.5 -102-190

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 62.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Korey Lee has hit the Home Runs Over in 2 of his last 7 games (+10.10 Units / 144% ROI)
  • Jacob Amaya has hit the Hits Under in 11 of his last 15 games (+6.60 Units / 39% ROI)
  • Jacob Amaya has hit the Total Bases Under in 11 of his last 15 games (+6.60 Units / 39% ROI)
  • Luis Robert has hit the Hits Runs and RBIs Under in his last 6 games (+6.40 Units / 78% ROI)
  • Miguel Vargas has hit the Runs Under in 8 of his last 9 games (+6.15 Units / 30% ROI)

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Kyle Manzardo has hit the Home Runs Over in 4 of his last 10 games at home (+14.90 Units / 149% ROI)
  • Gabriel Arias has hit the Singles Under in his last 10 games at home (+10.00 Units / 70% ROI)
  • Gabriel Arias has hit the Runs Under in 13 of his last 15 games at home (+8.45 Units / 25% ROI)
  • Gabriel Arias has hit the Total Bases Under in 8 of his last 10 games at home (+8.25 Units / 82% ROI)
  • Gabriel Arias has hit the Hits Under in 8 of his last 10 games at home (+8.25 Units / 82% ROI)
  • The Chicago White Sox have hit the Team Total Under in 25 of their last 37 away games (+12.40 Units / 29% ROI)
  • The Chicago White Sox have hit the Game Total Under in 20 of their last 34 away games (+9.15 Units / 25% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 8 of their last 13 away games (+3.65 Units / 26% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 13 away games (+3.30 Units / 25% ROI)
  • The Chicago White Sox have hit the Moneyline in 5 of their last 13 away games (+2.80 Units / 22% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 47 of their last 79 games (+17.00 Units / 19% ROI)
  • The Cleveland Guardians have covered the Run Line in 41 of their last 82 games at home (+10.15 Units / 11% ROI)
  • The Cleveland Guardians have hit the Moneyline in 51 of their last 81 games at home (+10.10 Units / 9% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 6 of their last 7 games at home (+5.75 Units / 70% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 7 of their last 10 games at home (+3.60 Units / 29% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 6-4 against the Run Line (+1.4 Units / 11.34% ROI).

  • 2-8 when betting on the Moneyline for -5 Units / -50% ROI
  • 5-4 when betting on the total runs Over for +0.7 Units / 6.42% ROI
  • 4-5 when betting on the total runs Under for -1.55 Units / -13.96% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 4-6 against the Run Line (-3.2 Units / -22.38% ROI).

  • 4-6 when betting on the Moneyline for -2.15 Units / -18.22% ROI
  • 5-5 when betting on the total runs Over for -0.15 Units / -1.4% ROI
  • 5-5 when betting on the total runs Under for -0.4 Units / -3.56% ROI

Guardians vs White Sox Home Run Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +475 0.5 -650
Carlos Santana (CLE) 0.5 +525 0.5 -750
Kyle Manzardo (CLE) 0.5 +550 0.5 -800
Andrew Vaughn (CWS) 0.5 +600 0.5 -900
Lane Thomas (CLE) 0.5 +650 0.5 -1000

Guardians vs White Sox Total Hits Prop Bets Today

Over Under
Andrew Vaughn (CWS) 0.5 -235 0.5 +180
Steven Kwan (CLE) 0.5 -225 0.5 +170
Jose Ramirez (CLE) 0.5 -225 0.5 +170
Lenyn Sosa (CWS) 0.5 -210 0.5 +160
Luis Robert (CWS) 0.5 -200 0.5 +155

Guardians vs White Sox RBI Prop Bets Today

Over Under
Andrew Vaughn (CWS) 0.5 +155 0.5 -210
Carlos Santana (CLE) 0.5 +170 0.5 -220
Jose Ramirez (CLE) 0.5 +175 0.5 -235
Kyle Manzardo (CLE) 0.5 +180 0.5 -235
Lenyn Sosa (CWS) 0.5 +195 0.5 -250

Guardians vs White Sox Strikeout Prop Bets Today

Over Under
Logan Allen (CLE) 4.5 +100 4.5 -135
Sean Burke (CWS) 4.5 +120 4.5 -160

Sean Burke has not walked any of the 43 batters that he has faced this season — best among among AL Starters; League Avg: 8% — 100th Percentile.

Sean Burke has not walked any of the 43 batters that he has faced over the last 14 days — best among AL Starters over the last two weeks; League Avg: 8% — 100th Percentile.

Sean Burke has a strikeout rate of just 9% (4 SO in 43 PAs) this season — 2nd lowest among among AL Starters; League Avg: 23% — fourth Percentile.

Sean Burke has a strikeout rate of just 6% (1 SO in 18 PAs) when going through the lineup the second time in a game this season — 2nd lowest among among AL Starters; League Avg: 23% — fourth Percentile.

Guardians Starting Pitcher Stats & Trends

Logan Allen has allowed a slugging percentage of .555 (222 Total Bases / 400 ABs) since last season — 4th highest in MLB among starting pitchers with at least 68 total IP; League Avg: .404 — second Percentile.

Logan Allen has allowed an OPS of .955 (377 PA’s) against right-handed batters since last season — highest in MLB among starting pitchers with at least 68 total IP; League Avg: .700 — 0 Percentile.

Logan Allen has walked 5 of 24 batters (21%) this season — 3rd highest in MLB among starting pitchers with at least 4 total IP; League Avg: 9% — first Percentile.

Logan Allen has allowed an OBP of .384 (375 PA’s) against right-handed batters since last season — highest in MLB among starting pitchers with at least 68 total IP; League Avg: .301 — 0 Percentile.

White Sox Keys to the Game vs. the Guardians

The White Sox were just 26-95 (.215) after a loss in the 2024 season — lowest in MLB; League Avg: .504.

The White Sox are just 42-110 (.276) when allowing 5 or more extra base hits since last season — lowest in MLB; League Avg: .537.

The White Sox are just 3-61 (.047) when allowing 10 or more hits since last season — lowest in MLB; League Avg: .249.

The White Sox were just 23-58 (.284) at home in the 2024 season — lowest in MLB; League Avg: .521.

Guardians Keys to the Game vs. the White Sox

The Guardians are 74-3 (.961) when leading entering the 7th inning since last season — best in MLB; League Avg: .858.

The Guardians were just 3-61 (.047) when trailing entering the 8th inning in the 2024 season — 2nd lowest in MLB; League Avg: .100.

The Guardians are 16-7 (.696) when tied entering the 7th inning since last season — 2nd best in MLB; League Avg: .498.

The Guardians were 77-2 (.975) when leading entering the 8th inning in the 2024 season — best in MLB; League Avg: .899.

White Sox hitters have an OPS of just .644 (9,263 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .721.

White Sox hitters have an OBP of just .282 (9,263 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .315.

White Sox hitters have an OBP of just .211 (6,476 PA’s) with two-strikes since the 2023 season — lowest in MLB; League Avg: .247.

The White Sox have a winning percentage of just 33% at home since the 2023 season — lowest in MLB; League Avg: 52%.

The Guardians are batting just .111 at home this season — lowest in MLB; League Avg: .251.

Guardians hitters are slugging just .111 at home this season — lowest in MLB; League Avg: .412.

Guardians hitters have an OPS of just .384 (33 PA’s) at home this season — lowest in MLB; League Avg: .740.

Guardians hitters had a Hard-Hit Rate of just 34% against RHP in the 2023 season — lowest in MLB; League Avg: 40%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

The White Sox won just 11% of games in which their opponents scored first last season — lowest in MLB; League Avg: 31%.

The White Sox won just 13% of home games in which their opponents scored first last season — lowest in MLB; League Avg: 35%.

The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 33%.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.

Opponents have a groundball batting average of just .210 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .262.

Guardians pitchers have a strikeout rate of just 18% this season — 2nd lowest in MLB; League Avg: 23%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.