White Sox vs Mets Prediction, Odds & Player Prop Bets Today – MLB, May 27

(AP Photo/Jeff Roberson)
  • The Mets are -275 favorites vs the White Sox
  • White Sox vs Mets Over / Under today: 8 Runs
  • White Sox / Mets TV Channel: SNY | CHSN

The Chicago White Sox (+220) visit Citi Field to take on the New York Mets (-275) on Tuesday, May 27, 2025. First pitch is scheduled for 7:10pm EDT in Flushing, NY.

This season, the White Sox are 17-37 against the spread (ATS), while the Mets are 27-27 ATS.

White Sox vs Mets Starting Pitchers Today:

  • White Sox starting pitcher: Jonathan Cannon 2-5, 3.77 ERA
  • Mets starting pitcher: Tylor Megill 3-4, 3.52 ERA

White Sox vs. Mets Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 +105O 8 -115+220
Mets -1.5 -125U 8 -105-275

White Sox vs Mets Prediction for Today’s Game

Based on recent trends the model predicts the Mets will win Tuesday‘s MLB game with 67.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Miguel Vargas has hit the Home Runs Over in 3 of his last 7 away games (+11.15 Units / 159% ROI)
  • Edgar Quero has hit the Runs Under in his last 10 away games (+10.00 Units / 49% ROI)
  • Chase Meidroth has hit the Hits Over in 13 of his last 15 games (+9.70 Units / 35% ROI)
  • Chase Meidroth has hit the Singles Over in 12 of his last 15 games (+8.75 Units / 51% ROI)
  • Chase Meidroth has hit the Total Bases Over in 12 of his last 15 games (+8.15 Units / 32% ROI)

And here are some favorite MLB player prop bets for Mets players for Tuesday‘s game, looking at profitable historical betting trends:

Best Mets Player Prop Best Bets Today:

  • Brett Baty has hit the Home Runs Over in 5 of his last 9 games at home (+35.90 Units / 399% ROI)
  • Jeff McNeil has hit the Singles Under in 19 of his last 25 games at home (+10.35 Units / 29% ROI)
  • Juan Soto has hit the Total Bases Under in 15 of his last 20 games (+9.50 Units / 33% ROI)
  • Pete Alonso has hit the Hits Over in 19 of his last 25 games at home (+9.40 Units / 20% ROI)
  • Jeff McNeil has hit the Runs Under in 13 of his last 15 games at home (+8.30 Units / 25% ROI)
  • The Chicago White Sox have hit the Team Total Under in 19 of their last 26 away games (+11.80 Units / 39% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 21 of their last 31 games (+11.30 Units / 33% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 14 of their last 30 games (+9.95 Units / 32% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 24 away games (+9.40 Units / 33% ROI)
  • The Chicago White Sox have hit the Game Total Under in 16 of their last 25 away games (+7.30 Units / 27% ROI)
  • The New York Mets have hit the Game Total Under in 34 of their last 54 games (+14.15 Units / 24% ROI)
  • The New York Mets have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 49 games (+10.19 Units / 17% ROI)
  • The New York Mets have hit the Moneyline in 20 of their last 26 games at home (+9.95 Units / 23% ROI)
  • The New York Mets have covered the 1st Five Innings (F5) Run Line in 17 of their last 26 games at home (+7.30 Units / 24% ROI)
  • The New York Mets have hit the Team Total Under in 9 of their last 12 games (+5.00 Units / 34% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 30-24 against the Run Line (+3.9 Units / 6.17% ROI).

  • 17-37 when betting on the Moneyline for -10.41 Units / -19.24% ROI
  • 24-27 when betting on the total runs Over for -5.8 Units / -9.75% ROI
  • 27-24 when betting on the total runs Under for +0.6 Units / 1.01% ROI

Mets Against the Spread (ATS) Record

Against the spread this season, the Mets are 27-27 against the Run Line (+0.44 Units / 0.64% ROI).

  • 33-21 when betting on the Moneyline for +4.25 Units / 5.32% ROI
  • 18-34 when betting on the total runs Over for -19.65 Units / -32.89% ROI
  • 34-18 when betting on the total runs Under for +14.15 Units / 23.96% ROI

Mets vs White Sox Home Run Prop Bets Today

Over Under
Pete Alonso (NYM) 0.5 +325 0.5 -450
Francisco Lindor (NYM) 0.5 +375 0.5 -500
Juan Soto (NYM) 0.5 +375 0.5 -500
Mark Vientos (NYM) 0.5 +475 0.5 -700
Brandon Nimmo (NYM) 0.5 +500 0.5 -700

Mets vs White Sox Total Hits Prop Bets Today

Over Under
Pete Alonso (NYM) 0.5 -250 0.5 +180
Brandon Nimmo (NYM) 0.5 -235 0.5 +175
Mark Vientos (NYM) 0.5 -220 0.5 +165
Juan Soto (NYM) 0.5 -220 0.5 +160
Jeff McNeil (NYM) 0.5 -190 0.5 +145

Mets vs White Sox RBI Prop Bets Today

Over Under
Pete Alonso (NYM) 0.5 +130 0.5 -175
Mark Vientos (NYM) 0.5 +145 0.5 -190
Brandon Nimmo (NYM) 0.5 +145 0.5 -190
Juan Soto (NYM) 0.5 +150 0.5 -200
Francisco Lindor (NYM) 0.5 +155 0.5 -210

Mets vs White Sox Strikeout Prop Bets Today

Over Under
Tylor Megill (NYM) 6.5 +120 6.5 -160
Jonathan Cannon (CWS) 4.5 +130 4.5 -165

Jonathan Cannon had an ERA of 7.05 (37.0 IP) against division opponents in the 2024 season — 2nd highest in MLB among starting pitchers with at least 64 total IP; League Avg: 3.95 — first Percentile.

Opponents had a line drive rate of 39% (25/65) versus Jonathan Cannon with runners in scoring position in the 2024 season — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 23% — 0 Percentile.

Opponents have a line drive rate of 32% (39/123) against Jonathan Cannon on changeups since the 2023 season — 2nd highest in MLB among starting pitchers with at least 150 total IP; League Avg: 22% — second Percentile.

Jonathan Cannon has an ERA of 6.92 (52.0 IP) against division opponents since last season — 4th highest in MLB among starting pitchers with at least 85 total IP; League Avg: 3.90 — second Percentile.

Mets Starting Pitcher Stats & Trends

Opponents have a groundball batting average of .391 (27 GB hits out of 69 GBs) against Tylor Megill with runners in scoring position since the 2023 season — tied for highest in MLB among starting pitchers with at least 150 total IP; League Avg: .243 — first Percentile.

Tylor Megill has allowed an OBP of .441 (127 PA’s) with runners in scoring position since last season — highest in MLB among starting pitchers with at least 85 total IP; League Avg: .315 — 0 Percentile.

Opponents have a groundball batting average of .588 (10 GB hits out of 17 GBs) against Tylor Megill with runners in scoring position this season — highest in MLB among starting pitchers with at least 20 total IP; League Avg: .240 — first Percentile.

Opponents batted .392 (40-for-102) against Tylor Megill when going through the lineup the third time in a game in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: .263 — first Percentile.

White Sox Keys to the Game vs. the Mets

The White Sox were just 26-95 (.215) after a loss in the 2024 season — lowest in MLB; League Avg: .504.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox were just 18-63 (.222) on the road in the 2024 season — lowest in MLB; League Avg: .478.

The White Sox were just 4-40 (.091) when their opponents score in the first inning in the 2024 season — lowest in MLB; League Avg: .359.

Mets Keys to the Game vs. the White Sox

The Mets were 8-60 (.118) when trailing entering the 9th inning in the 2024 season — best in MLB; League Avg: .050.

The Mets are 20-6 (.769) at home this season — best in MLB; League Avg: .561.

The Mets are 4-2 (.667) vs the top 10 runs allowed teams this season They play the White Sox (28th best runs allowed) today.

The Mets are 8-78 (.093) when trailing entering the 9th inning since last season — best in MLB; League Avg: .048.

The White Sox have a winning percentage of just 21% on the road since last season — lowest in MLB; League Avg: 47%.

The White Sox have a winning percentage of just 27% since last season — lowest in MLB; League Avg: 50%.

White Sox hitters have an OBP of just .289 (6,818 PA’s) at home since the 2023 season — lowest in MLB; League Avg: .320.

The White Sox have a winning percentage of just 32% since the 2023 season — lowest in MLB; League Avg: 50%.

Mets hitters have a groundball batting average of just .166 with runners on base this season — lowest in MLB; League Avg: .258.

Mets hitters slugged .440 against LHP in the 2024 season — 5th best in MLB; League Avg: .397.

The Mets are batting just .292 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .339.

The Mets batted just .238 against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .254.

In games when their opponents have scored three or more runs in an inning, the White Sox have won just just 4% of the time since last season — lowest in MLB; League Avg: 24%.

The White Sox have won just 6% of road games in which their opponents scored first since last season — lowest in MLB; League Avg: 26%.

The White Sox have won just 20% of home games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 37%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

Mets pitchers walked 586 of 6,098 batters (10%) in the 2024 season — 3rd highest in MLB; League Avg: 8%.

Opponents have a groundball rate of 52% against Mets pitchers over the last 14 days — highest in MLB; League Avg: 42%.

Mets pitchers have walked 10% of batters since last season — 3rd highest in MLB; League Avg: 8%.

Opponents have a groundball rate of 48% against Mets pitchers this season — 2nd highest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.