White Sox vs Royals Prediction, Odds & Player Prop Bets Today – MLB, May 6

Kansas City Royals' Bobby Witt Jr. during a baseball game against the Colorado Rockies in Kansas City, Mo., Saturday, June 3, 2023.
(AP Photo/Colin E. Braley)
  • The Royals are -220 favorites vs the White Sox
  • White Sox vs Royals Over / Under today: 8.5 Runs
  • White Sox / Royals TV Channel: FDKC | CHSN

The Chicago White Sox (+180) visit Kauffman Stadium to take on the Kansas City Royals (-220) on Tuesday, May 6, 2025. First pitch is scheduled for 7:40pm EDT in Kansas City, MO, MO.

This season, the White Sox are 10-25 against the spread (ATS), while the Royals are 18-18 ATS.

White Sox vs Royals Starting Pitchers Today:

  • White Sox starting pitcher: Sean Burke 2-4, 4.91 ERA
  • Royals starting pitcher: Seth Lugo 3-3, 3.12 ERA

White Sox vs. Royals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -115O 8.5 -105+180
Royals -1.5 -105U 8.5 -115-220

White Sox vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Royals will win Tuesday‘s MLB game with 65.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Luis Robert has hit the Home Runs Over in 3 of his last 9 games (+13.20 Units / 147% ROI)
  • Miguel Vargas has hit the Singles Over in 8 of his last 10 games (+9.30 Units / 93% ROI)
  • Lenyn Sosa has hit the Hits Over in his last 9 away games (+9.00 Units / 48% ROI)
  • Miguel Vargas has hit the Total Bases Over in 12 of his last 15 games (+7.70 Units / 37% ROI)
  • Andrew Benintendi has hit the Runs Over in his last 5 games (+7.40 Units / 148% ROI)

And here are some favorite MLB player prop bets for Royals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

  • Vinnie Pasquantino has hit the Home Runs Over in 4 of his last 9 games (+23.90 Units / 266% ROI)
  • Michael Massey has hit the Runs Under in 19 of his last 20 games at home (+17.40 Units / 46% ROI)
  • Michael Massey has hit the Hits Runs and RBIs Under in 14 of his last 20 games at home (+8.05 Units / 33% ROI)
  • Maikel Garcia has hit the Hits Over in 7 of his last 8 games (+7.45 Units / 52% ROI)
  • Jonathan India has hit the Total Bases Over in 7 of his last 8 games (+7.05 Units / 63% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 10 of their last 12 games (+8.50 Units / 64% ROI)
  • The Chicago White Sox have hit the Team Total Under in 11 of their last 16 away games (+5.90 Units / 32% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 14 away games (+5.70 Units / 34% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 11 games (+5.65 Units / 51% ROI)
  • The Chicago White Sox have hit the Game Total Over in 7 of their last 19 games (+3.60 Units / 17% ROI)
  • The Kansas City Royals have hit the Team Total Under in 26 of their last 36 games (+15.45 Units / 37% ROI)
  • The Kansas City Royals have hit the Moneyline in 12 of their last 14 games (+12.35 Units / 64% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 9 of their last 12 games (+7.85 Units / 49% ROI)
  • The Kansas City Royals have covered the 1st Five Innings (F5) Run Line in 10 of their last 12 games (+7.35 Units / 48% ROI)
  • The Kansas City Royals have covered the Run Line in 10 of their last 12 games (+7.05 Units / 42% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 18-17 against the Run Line (-0.4 Units / -0.98% ROI).

  • 10-25 when betting on the Moneyline for -8.6 Units / -24.57% ROI
  • 17-16 when betting on the total runs Over for -0.7 Units / -1.21% ROI
  • 16-17 when betting on the total runs Under for -2.7 Units / -4.66% ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 18-18 against the Run Line (-5.9 Units / -11.52% ROI).

  • 20-16 when betting on the Moneyline for +4.85 Units / 11.04% ROI
  • 12-23 when betting on the total runs Over for -12.9 Units / -22.95% ROI
  • 23-12 when betting on the total runs Under for +9.75 Units / 16.94% ROI

Royals vs White Sox Home Run Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +375 0.5 -525
Bobby Witt Jr. (KC) 0.5 +425 0.5 -600
Vinnie Pasquantino (KC) 0.5 +550 0.5 -800
Luis Robert (CWS) 0.5 +575 0.5 -800
Andrew Vaughn (CWS) 0.5 +650 0.5 -1000

Royals vs White Sox Total Hits Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 -250 0.5 +185
Andrew Vaughn (CWS) 0.5 -250 0.5 +185
Lenyn Sosa (CWS) 0.5 -220 0.5 +165
Chase Meidroth (CWS) 0.5 -220 0.5 +160
Jonathan India (KC) 0.5 -220 0.5 +165

Royals vs White Sox RBI Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +120 0.5 -160
Bobby Witt Jr. (KC) 0.5 +125 0.5 -165
Vinnie Pasquantino (KC) 0.5 +145 0.5 -190
Maikel Garcia (KC) 0.5 +170 0.5 -225
Andrew Vaughn (CWS) 0.5 +175 0.5 -235

Royals vs White Sox Strikeout Prop Bets Today

Over Under
Seth Lugo (KC) 4.5 -145 4.5 +110
Sean Burke (CWS) 3.5 +100 3.5 -130

Sean Burke has thrown his fastball for a strike just 55% (141/258) of the time this season — lowest in MLB among starting pitchers with at least 13 total IP; League Avg: 67% — 0 Percentile.

Sean Burke has walked 18% of left-handed batters this season — 3rd highest in MLB among starting pitchers with at least 13 total IP; League Avg: 9% — third Percentile.

Sean Burke has allowed three-ball counts to 35% of batters they faced (23/65 PA’s) vs left-handed batters this season — highest in MLB among starting pitchers with at least 13 total IP; League Avg: 22% — first Percentile.

Opponents are hitting just .071 (2-for-28) against Sean Burke’s elevated fastball this season — 4th best in MLB among starting pitchers with at least 13 total IP; League Avg: .225 — 97th Percentile.

Royals Starting Pitcher Stats & Trends

Seth Lugo has a first-pitch strike rate of 74% (129/174) this season — highest among among AL Starters; League Avg: 63% — 100th Percentile.

Seth Lugo has walked 4% of right-handed batters since last season — 3rd best among qualified SPs in MLB; League Avg: 6% — 95th Percentile.

Seth Lugo has allowed an OBP of just .248 (459 PA’s) against right-handed batters since last season — 3rd best among qualified SPs in MLB; League Avg: .287 — 95th Percentile.

Seth Lugo has walked 3% of right-handed batters this season — 5th best among qualified SPs in MLB; League Avg: 7% — 95th Percentile.

White Sox Keys to the Game vs. the Royals

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 33-112 (.228) after a loss since last season — lowest in MLB; League Avg: .502.

The White Sox are just 21-76 (.216) on the road since last season — lowest in MLB; League Avg: .468.

The White Sox were just 18-63 (.222) on the road in the 2024 season — lowest in MLB; League Avg: .478.

Royals Keys to the Game vs. the White Sox

The Royals were just 4-50 (.074) when they allowed 5 or more runs in the 2024 season — 2nd lowest in MLB; League Avg: .196.

The Royals are just 1-6 (.143) vs top 10 scoring offenses this season They play the White Sox (30th best runs scored) today.

The Royals are just 5-59 (.078) when allowing 5 or more runs since last season — 2nd lowest in MLB; League Avg: .191.

The Royals are just 17-34 (.333) vs top 10 scoring offenses since last season They play the White Sox (30th best runs scored) today.

White Sox hitters have an OBP of just .285 (9,898 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .316.

White Sox hitters have an OBP of just .286 (13,127 PA’s) since the 2023 season — lowest in MLB; League Avg: .316.

White Sox hitters have an OBP of just .213 (6,997 PA’s) with two-strikes since the 2023 season — lowest in MLB; League Avg: .247.

White Sox hitters have an OPS of just .645 (13,127 PA’s) since the 2023 season — lowest in MLB; League Avg: .722.

Royals hitters have struck out in just 19% of it’s PA’s since last season — 2nd best in MLB; League Avg: 22%.

Royals hitters have an OBP of just .301 (3,257 PA’s) against LHP since the 2023 season — 3rd lowest in MLB; League Avg: .318.

The Royals are batting just .318 on the first pitch of at-bats since the 2023 season — 2nd lowest in MLB; League Avg: .340.

Royals hitters have struck out in just 19% of it’s PA’s against RHP since last season — 2nd best in MLB; League Avg: 22%.

White Sox pitchers have walked 10% of batters since last season — highest in MLB; League Avg: 8%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

White Sox pitchers had a strike rate of just 62% in the 2024 season — lowest in MLB; League Avg: 64%.

White Sox pitchers have walked 10% of batters since the 2023 season — highest in MLB; League Avg: 8%.

The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4

Royals pitchers have a strikeout rate of just 20% in close and late situations since last season — tied for lowest in MLB; League Avg: 25%.

Batters facing the Royals pitchers have struck out in the zone 57% of the time this season — 2nd highest in MLB; League Avg: 51%. this season — 2nd highest in MLB; League Avg: 51%.

Royals pitchers have an ERA of 3.31 (163.1 IP) on the road this season — best in MLB; League Avg: 4.37.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.