BYU posted the single biggest comeback in the history of the NCAA Tournament in 2012, roaring back from a 25-point deficit to ultimately dispatch No. 14 seed Iona, 78-72, in an epic first-round game.
March Madness comebacks are notoriously hard to track because the sport is so fluid, and the bracket is so large.
Additionally, some people prefer different ingredients in a big comeback. Some college basketball fans are most impressed by an improbable comeback in the final minute of the game.
Others are more interested in huge comebacks in the Final Four, when the lights are the absolute brightest.
For this list here, you’ll see raw deficits. Simply put, these are the biggest comebacks by total points that have ever been successfully overcome – ending in a victory – in the history of the NCAA Tournament.
Biggest Comebacks in March Madness History
| Score | Biggest Deficit | Year | Round |
|---|---|---|---|
| BYU 78, Iona 72 | 25 Points | 2012 | Round 1 |
| Duke 95, Maryland 84 | 22 Points | 2001 | Final Four |
| Nevada 75, Cincinnati 73 | 22 Points | 2018 | Round 2 |
| Louisville 93, West Virginia 85 | 20 Points | 2018 | Regional Final |
| Ole Miss 94, BYU 90 | 17 Points | 2015 | First Four |
| UCLA 73, Gonzaga 71 | 17 Points | 2006 | Sweet 16 |
| WKU 59, Miss. Valley St 58 | 16 Points | 2012 | First Four |
| Kansas 72, North Carolina 69 | 16 Points | 2022 | Championship |
| Loyola (Chi) 60, Cincinnati 58 | 15 Points | 1963 | Championship |
| Illinois 90, Arizona 89 | 15 Points | 2005 | Regional Final |
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