Clemson vs Louisville Prediction, Odds & Best Bets Today – NCAAB, Jan. 7

Louisville head coach Pat Kelsey shouts instructions to his team during the second half of an NCAA college basketball game against Tennessee in Louisville, Ky., Saturday, Nov. 9, 2024. Tennessee won 77-55. (AP Photo/Timothy D. Easley)
(AP Photo/Timothy D. Easley)
  • Louisville is a -3.5 point favorite vs Clemson
  • Total (Over/Under): 145.5 points
  • Clemson / Louisville TV channel: ESPNU

The Clemson Tigers visit KFC Yum! Center to take on the Louisville Cardinals on Jan. 7. Tip off is scheduled for 7:00pm EST in Louisville, KY.

Louisville is the betting favorite in this game, with the spread sitting at -3.5 (-110).

The Clemson vs. Louisville Over/Under is 145.5 total points.

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Clemson vs. Louisville Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Clemson+3.5 -110O 145.5 -115+140
Louisville -3.5 -110U 145.5 -105-165

Clemson vs Louisville Prediction for Today:

The winning team model predicts Clemson will win this college basketball game with 77.7% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Clemson vs Louisville Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Louisville will cover the spread with 60.1% confidence for today’s game.


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  • Clemson has hit the 1H Moneyline in 24 of their last 37 games (+6.73 Units / 1% ROI)
  • Clemson has hit the 1H Game Total Under in 22 of their last 37 games (+4.95 Units / 12% ROI)
  • Clemson has hit the Game Total Under in 10 of their last 16 away games (+3.40 Units / 19% ROI)
  • Clemson have covered the Spread in 10 of their last 16 away games (+3.40 Units / 19% ROI)
  • Clemson has hit the Moneyline in 9 of their last 16 away games (+3.30 Units / 14% ROI)
  • Louisville has hit the Game Total Under in 21 of their last 33 games (+7.85 Units / 22% ROI)
  • Louisville has hit the Team Total Under in 12 of their last 20 games at home (+2.92 Units / 13% ROI)
  • Louisville has hit the Moneyline in 13 of their last 33 games (+1.45 Units / 1% ROI)

Clemson Basketball Against the Spread Record (ATS)

Clemson has a 8-7 record against the spread this college basketball season (+0.3 Units / 1.82% ROI).

  • 12-3 when betting on the Moneyline for +7.3 Units / 2.14% ROI
  • 8-7 when betting the Over for +0.3 Units / 1.83% ROI
  • 7-8 when betting the Under for -1.9 Units / -11.45% ROI

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 8-7 record against the spread this college basketball season (+0.3 Units / 1.82% ROI).

  • 10-5 when betting on the Moneyline for +4 Units / 1.74% ROI
  • 4-11 when betting the Over for -8.15 Units / -49.24% ROI
  • 11-4 when betting the Under for +6.65 Units / 40.3% ROI

Clemson Offensive Stats & Trends:

Clemson is shooting 79% from the free throw line (126/159) in the second half this season — best among ACC Teams; League Avg: 74%

Clemson is shooting 38% from three (134/354) this season — tied for 17th best among Division 1 Teams; League Avg: 34%

Clemson averaged 1.32 points per shot (2,640 points/2,005 shots) last season — tied for 31st best among Division 1 Teams; League Avg: 1.25

Clemson has averaged 4.4 turnovers per game (66 turnovers/15 games) in the second half this season — 2nd best among ACC Teams; League Avg: 5.5

Louisville Offensive Stats & Trends:

Louisville is shooting 29% from three (188/656) at home since the start of the 2023-24 season — lowest among ACC Teams; League Avg: 35%

Louisville shot 28% from three (77/275) in the first half last season — lowest among ACC Teams; League Avg: 35%

Louisville had an assist to turnover ratio of 0.7 (154 assists/ 231 TOs) in the first half last season — lowest among ACC Teams; League Avg: 1.2

Louisville has an assist to turnover ratio of 0.8 (252 assists/ 330 TOs) in the first half since the start of the 2023-24 season — lowest among ACC Teams; League Avg: 1.2

Clemson Defensive Stats & Trends:

Clemson averaged 4.6 steals per game (156 steals/34 games) last season — 5th lowest among Power Conference teams; League Avg: 6.6

Clemson averaged 4.6 steals per game (156 steals/34 games) last season — tied for 14th lowest among Division 1 Teams; League Avg: 6.7

Clemson averaged 4.6 steals per game (156 steals/34 games) last season — 2nd lowest among ACC Teams; League Avg: 6.4

Clemson has averaged 5.6 steals per game (275 steals/49 games) since the start of the 2023-24 season — tied for 28th lowest among Division 1 Teams; League Avg: 6.8

Louisville Defensive Stats & Trends:

Louisville allowed opponents to shoot 48% (450/927) in the first half last season — highest among ACC Teams; League Avg: 43%

Louisville allowed an average of 1.40 points per shot (1,958 points/1,397 shots) last season — 5th highest among Power Conference defenses; League Avg: 1.28

Louisville allowed opponents to shoot 37% from three (266/714) last season — highest among ACC Teams; League Avg: 34%

Louisville allowed an average of 1.35 points per shot (2,463 points/1,827 shots) last season — tied for highest among Division 1 Teams; League Avg: 1.23


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