- The Cardinals are a 1.5-point home underdog against the Chargers.
- The Cardinals have lost each of their last six home games against AFC opponents.
- My Cardinals vs. Chargers prediction rests on the status of Marvin Harrison Jr.
For the second game of a Monday Night Football doubleheader, the Arizona Cardinals host the Los Angeles Chargers.
Arizona has dropped three of its previous four contests to sit at 2-4 on the season. In Week 6, they received a 34-13 thrashing from the Packers in Green Bay.
The Chargers emerged from their Week 5 bye and handled the Broncos 23-16 in Denver, ending a two-game losing streak. Still, the Chargers sit two games behind the Chiefs in the division.
Bet on Cardinals vs. Chargers and other NFL matchups with up-to-date NFL odds.
NFL Week 7 Odds: Cardinals vs. Chargers
| Spread | Total (O/U) | Moneyline | |
|---|---|---|---|
| Chargers | -1.5 (-110) | 44 (-110) | -125 |
| Cardinals | +1.5 (-110) | 44 (-110) | +105 |
Cardinals vs. Chargers Prediction, MNF
If Marvin Harrison Jr. doesn’t play for the Cardinals on Monday, my Cardinals vs. Chargers prediction is the Cardinals Team Total Under 20.5 Points (+105).
Arizona enjoyed a strong start to the season, clearing this number in each of its first two games. However, its offensive metrics have fallen off in the last four contests.
Since Week 3, the Cardinals are 25th in expected points added per play and 16th in offensive success rate, per rbsdm.com.
In Week 7, Jonathan Gannon’s squad has to play a second consecutive game against a team 10th or better by EPA per play.
The difference between Green Bay and Los Angeles? The Chargers are third in defensive success rate while Green Bay ranks 28th.
Los Angeles hasn’t allowed a team to clear this number all season while Arizona has needed some luck to overtake this total.
In Week 1, they used a kickoff return for a touchdown and subsequent two-point conversion to clear this total. In Week 5 against San Francisco, it was a 50-yard Kyler Murray rush touchdown that helped them amass 23 points.
The only inspiring offensive performance by Arizona came in Week 2 against Los Angeles, a team 31st in defensive EPA per play off a road overtime game.
With the Chargers playing its second consecutive game on extra rest, I’ll back their defense to continue the streak of keeping teams under 20 points.
Cardinals vs. Chargers: NFL Public Betting Trends
| Bets% (Spread) | Money% (Spread) | Bets% (ML) | Money% (ML) | |
|---|---|---|---|---|
| Chargers | 67% | 54% | 53% | 48% |
| Cardinals | 33% | 46% | 47% | 52% |
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