White Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, May 24

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM May 24, 2023, 3:32 PM
  • The are favorites vs the
  • White Sox starting pitcher: Michael Kopech
  • Guardians starting pitcher: Cal Quantrill
  • Watch the game on BSGL

The Chicago White Sox () visit Progressive Field to take on the Cleveland Guardians () on Wednesday, May 24, 2023. First pitch is scheduled for 1:10pm EDT in Cleveland.

The are the betting favorite in this game, with the run line sitting at ().

The White Sox vs Guardians Over/Under is total runs for the game.

This season, the White Sox are 20-30 against the spread (ATS), while the Guardians are 21-27 ATS.

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox O
Guardians U

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB matchup with 54.6% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the White Sox and Guardians and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Luis Robert has hit the Total Bases Over in 16 of his last 21 games (+12.55 Units / 46% ROI)
  • Tim Anderson has hit the Runs Under in his last 12 games (+12.00 Units / 63% ROI)
  • Elvis Andrus has hit the Runs Under in 19 of his last 22 away games (+11.95 Units / 23% ROI)
  • Tim Anderson has hit the Total Bases Under in 14 of his last 16 games (+10.25 Units / 40% ROI)
  • Tim Anderson has hit the Hits Runs and RBIs Under in 13 of his last 16 games (+10.20 Units / 51% ROI)

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Josh Bell has hit the Runs Under in 39 of his last 46 games (+25.95 Units / 29% ROI)
  • Jose Ramirez has hit the Hits Over in 35 of his last 45 games (+15.10 Units / 15% ROI)
  • Andres Gimenez has hit the Runs Under in 15 of his last 16 games (+12.85 Units / 37% ROI)
  • Steven Kwan has hit the Singles Under in 15 of his last 21 games (+11.55 Units / 54% ROI)
  • Myles Straw has hit the Singles Under in 16 of his last 20 games (+11.25 Units / 45% ROI)

Guardians vs White Sox Home Run Prop Bets Today

Over Under
Romy Gonzalez 0.5 +700 0.5 -2500
Gavin Sheets 0.5 +525 0.5 -1200
Tim Anderson 0.5 +900 0.5 -5000
Amed Rosario 0.5 +750 0.5 -3000
Steven Kwan 0.5 +1050 0.5

Guardians vs White Sox Total Hits Prop Bets Today

Over Under
Romy Gonzalez 0.5 -155 0.5 +115
Gavin Sheets 0.5 -225 0.5 +165
Tim Anderson 1.5 +160 1.5 -210
Amed Rosario 1.5 +185 1.5 -250
Steven Kwan 0.5 -250 0.5 +190

Guardians vs White Sox RBI Prop Bets Today

Over Under
Romy Gonzalez 0.5 +240 0.5 -350
Gavin Sheets 0.5 +160 0.5 -225
Tim Anderson 0.5 +260 0.5 -375
Amed Rosario 0.5 +180 0.5 -250
Steven Kwan 0.5 +240 0.5 -350

Guardians vs White Sox Strikeout Prop Bets Today

Over Under
Michael Kopech 4.5 -115 4.5 -115
Cal Quantrill 4.5 +100 4.5 -130
  • The Chicago White Sox have hit the Game Total Under in 10 of their last 12 games (+8.90 Units / 67% ROI)
  • The Chicago White Sox have covered the Run Line in 8 of their last 10 games (+6.85 Units / 54% ROI)
  • The Chicago White Sox have hit the Team Total Under in 18 of their last 29 games (+6.35 Units / 19% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 5 of their last 6 games (+4.60 Units / 71% ROI)
  • The Chicago White Sox have hit the Moneyline in 13 of their last 22 games (+3.95 Units / 15% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 30 of their last 41 games (+18.10 Units / 37% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 23 of their last 32 games (+15.45 Units / 44% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 8 games at home (+5.70 Units / 55% ROI)
  • The Cleveland Guardians have covered the Run Line in 5 of their last 6 games (+4.65 Units / 55% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 6 of their last 12 games at home (+2.40 Units / 15% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this MLB season, the White Sox have gone 25-25 against the Run Line (-2.85 Units / -4.4% ROI).

  • 20-30 when betting on the Moneyline for -11.1 Units / -19.2% ROI
  • 22-24 when betting on the total runs Over for -4.05 Units / -7.38% ROI
  • 24-22 when betting on the total runs Under for -0.05 Units / -0.09% ROI

Guardians Against the Spread (ATS) Record

Against the spread this MLB season, the Guardians have gone 21-27 against the Run Line (-7.6 Units / -12.44% ROI).

  • 21-27 when betting on the Moneyline for -13.1 Units / -20.99% ROI
  • 16-29 when betting on the total runs Over for -15.85 Units / -30.05% ROI
  • 29-16 when betting on the total runs Under for +11.6 Units / 21.93% ROI

starting pitcher – away

Guardians Starting Pitcher Stats & Trends

Right-handed hitters have a miss rate of just 14% (31/225) against Cal Quantrill this season — lowest among qualified SPs in MLB; League Avg: 26% — first Percentile.

Cal Quantrill has a strikeout rate of just 15% (8 SO in 52 PAs) on low non-fastballs this season — lowest among qualified SPs in MLB; League Avg: 34% — first Percentile.

Cal Quantrill has allowed an OPS of .756 (100 PA’s) with two-strikes this season — 2nd highest among qualified SPs in MLB; League Avg: .505 — second Percentile.

Opponents have a miss rate of just 16% (65/396) against Cal Quantrill this season — 3rd lowest among qualified SPs in MLB; League Avg: 26% — third Percentile.

White Sox Keys to the Game vs. the Guardians

The White Sox are just 0-7 (.000) after a road win this season — lowest in MLB; League Avg: .479.

The White Sox are just 5-14 (.263) after a win this season — 2nd lowest in MLB; League Avg: .516.

The White Sox are just 15-5 (.750) when leading entering the 7th inning this season — 2nd lowest in MLB; League Avg: .859.

The White Sox are just 19-24 (.442) when allowing 5 or more extra base hits this season — 4th lowest in MLB; League Avg: .535.

Guardians Keys to the Game vs. the White Sox

The Guardians are 22-73 (.232) when trailing entering the 7th inning since last season — best in MLB; League Avg: .124.

The Guardians are 16-78 (.170) when trailing entering the 8th inning since last season — best in MLB; League Avg: .088.

The Guardians were 16-57 (.219) when trailing entering the 7th inning in 2022 — best in MLB; League Avg: .118.

The Guardians are just 13-4 (.765) when leading entering the 7th inning this season — 3rd lowest in MLB; League Avg: .859.

White Sox hitters have an OBP of just .169 (238 PA’s) with two-strikes over the last 14 days (13 games) — lowest in MLB; League Avg: .244.

White Sox hitters have drawn 369 walks in 6,271 PA’s (6%) against RHP since last season — lowest in MLB; League Avg: 8%.

The White Sox have won just 20% of games in which they have scored first on the road this season — 2nd lowest in MLB; League Avg: 64%.

White Sox hitters have 126 extra-base hits out of 405 total hits (just 31%) with the pitcher behind in the count since last season — lowest in MLB; League Avg: 40%.

Guardians hitters have just 1,030 strikeouts in 5,824 PA’s (18%) against RHP since last season — best in MLB; League Avg: 23%.

Guardians hitters have an OPS of just .643 (2,116 PA’s) against LHP since last season — 2nd lowest in MLB; League Avg: .722.

Guardians hitters are slugging just .342 against LHP since last season — lowest in MLB; League Avg: .404.

Guardians hitters have an OPS of just .633 (537 PA’s) against LHP this season — lowest in MLB; League Avg: .747.

The White Sox pitchers have allowed their opponents to score first in 80% of their games on the road this season — highest in MLB; League Avg: 49%.

Opponents have a groundball rate of just 40% against White Sox pitchers this season — 2nd lowest in MLB; League Avg: 43%.

White Sox pitchers have walked 44 of 444 batters (10%) when facing the leadoff batter in the inning this season — 5th highest in MLB; League Avg: 8%.

Opponents have a groundball rate of just 41% against White Sox pitchers since last season — 4th lowest in MLB; League Avg: 43%.

Guardians pitchers have walked 111 of 1,892 batters (6%) when facing the leadoff batter in the inning since last season — best in MLB; League Avg: 8%.

Guardians pitchers have walked 23 of 432 batters (5%) when facing the leadoff batter in the inning this season — best in MLB; League Avg: 8%.

Guardians pitchers have walked 564 of 7,806 batters (7%) since last season — 3rd best in MLB; League Avg: 8%.

Opponents have a groundball rate of just 41% against Guardians pitchers this season — 4th lowest in MLB; League Avg: 43%.

Guardians vs. White Sox Injuries Tonight That May Affect Prop Bets 

  • Aaron Civale (Guardians): Oblique, D15
  • Peyton Battenfield (Guardians): Shoulder, D15
  • Triston McKenzie (Guardians): Shoulder, D60
  • Cody Morris (Guardians): Shoulder, D60
  • Billy Hamilton (White Sox): Hamstring, D10
  • Michael Clevinger (White Sox): Wrist, D15
  • Liam Hendriks (White Sox): Illness, D15
  • Matthew Foster (White Sox): Forearm, D60
  • Eloy Jiménez (White Sox): Appendix, D10
  • Luis Robert Jr. (White Sox): Hip, Day-to-Day
  • Elvis Andrus (White Sox): Oblique, D10
  • Hanser Alberto (White Sox): Shoulder, Day-to-Day

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.