Clemson vs Pitt Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 12

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Pittsburgh wide receiver Daejon Reynolds (3) tries to make a catch during the first half of an NCAA college football game against Notre Dame Saturday, Oct. 28, 2023, in South Bend, Ind. (AP Photo/Michael Caterina)
(AP Photo/Michael Caterina)
BetMGM Betting @BETMGM Nov 13, 2024, 4:15 PM
  • Clemson is a -10 point favorite vs. Pitt
  • Clemson vs. Pittsburgh Total (Over/Under): 53.5 points
  • TV Channel: ESPN

The Clemson Tigers (7-2) visit Acrisure Stadium to take on the Pittsburgh Panthers (7-2) on Nov. 16 in Pittsburgh, PA. Kickoff is scheduled for 12:00pm EST.

Clemson is a betting favorite in Week 12, with the spread sitting at -10 (-110).

The Clemson vs. Pittsburgh Over/Under is 53.5 total points.

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Clemson vs. Pittsburgh Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Clemson-10 -11053.5 -110-375
Pittsburgh +10 -11053.5 -110+300

Clemson vs Pittsburgh Prediction:

The winning team model predicts Clemson will win this game with 76.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Clemson and Pitt, key player performances this season and recent team trends.

Clemson vs Pittsburgh Spread Prediction:

Based on recent against-the-spread trends, the model predicts Pittsburgh will cover the spread with 86.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Clemson has hit the Moneyline in 10 of their last 12 games (+5.10 Units / 6% ROI)
  • Clemson has hit the Game Total Under in 4 of their last 6 away games (+2.90 Units / 44% ROI)
  • Clemson have covered the 1H Spread in 4 of their last 6 away games (+1.80 Units / 28% ROI)
  • Clemson has hit the 1Q Game Total Under in 7 of their last 11 games (+1.80 Units / 14% ROI)
  • Clemson has hit the 1H Game Total Under in 7 of their last 12 games (+1.55 Units / 12% ROI)
  • Pittsburgh have covered the 1H Spread in 6 of their last 7 games at home (+6.00 Units / 76% ROI)
  • Pittsburgh has hit the 1H Moneyline in 6 of their last 7 games at home (+6.00 Units / 11% ROI)
  • Pittsburgh has hit the 1Q Moneyline in 4 of their last 5 games at home (+4.00 Units / 37% ROI)
  • Pittsburgh has hit the Moneyline in 8 of their last 11 games (+3.25 Units / 4% ROI)
  • Pittsburgh have covered the Spread in 5 of their last 7 games at home (+2.75 Units / 35% ROI)

We’ve highlighted some favorite college football player prop bets for Clemson players, looking at profitable historical betting trends:

Best Clemson Player Prop Bets Today

  • Jake Briningstool has hit the Receiving Yards Over in his last 2 away games (+2.00 Units / 83% ROI)
  • Antonio Williams has hit the Receiving Yards Over in his last 2 away games (+2.00 Units / 83% ROI)
  • Phil Mafah has hit the Rushing Yards Over in his last 2 games (+2.00 Units / 83% ROI)
  • Cade Klubnik has hit the Rushing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Tyler Brown has hit the Receiving Yards Under in his last game (+1.00 Units / 80% ROI)

Top NCAAF player prop bets for Pittsburgh players, looking at profitable historical betting trends:

Best Pittsburgh Player Prop Best Bets Today

  • Konata Mumpfield has hit the Receiving Yards Under in his last 3 games at home (+3.00 Units / 83% ROI)
  • Desmond Reid has hit the Receiving Yards Over in his last 2 games (+2.00 Units / 83% ROI)
  • Kenny Johnson has hit the Receiving Yards Under in his last 2 games at home (+2.00 Units / 83% ROI)
  • Eli Holstein has hit the Passing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Gavin Bartholomew has hit the Receiving Yards Under in his last game (+1.00 Units / 83% ROI)

Clemson Against the Spread (ATS) Record

Clemson is 5-4 against the spread this college football season (+0.6 Units / 6.09% ROI).

  • Clemson is 7-2 when betting on the Moneyline for +2.1 Units / 2.56% ROI
  • Clemson is 3-5 when betting the Over for -2.5 Units / -25.25% ROI
  • Clemson is 5-3 when betting the Under for +1.7 Units / 17.17% ROI

Pittsburgh Against the Spread (ATS) Record

Pitt is 6-3 against the spread this college football season (+2.65 Units / 26.63% ROI).

  • Pittsburgh is 7-2 when betting on the Moneyline for +3.25 Units / 4.34% ROI
  • Pittsburgh is 4-5 when betting the Over for -1.5 Units / -15.15% ROI
  • Pittsburgh is 5-4 when betting the Under for +0.6 Units / 6.06% ROI

Clemson: Keys to the Game vs. Pittsburgh

Clemson is 9-2 (.818) when the opposing team rushes more than 30 times since the 2023 season– 3rd-best among Power Conference Teams; Average: .490

Clemson is 9-2 (.818) when the opposing team rushes more than 30 times since the 2023 season– 4th-best in FBS; Average: .446

Clemson is 16-3 (.842) when rushing at least 4 yards in a play 10 or more times since the 2023 season– 12th-best in FBS; Average: .582

Clemson is 13-3 (.812) when allowing less than 5 explosive passes since the 2023 season– 14th-best among Power Conference Teams; Average: .683

Pittsburgh: Keys to the Game vs. Clemson

Pittsburgh is 2-7 (.222) when allowing an average of more than 5 yards on first down plays since the 2023 season– T-5th-worst among Power Conference Teams; Average: .491

Pittsburgh is 6-5 (.545) when rushing more than 30 times since the 2023 season– T-15th-worst among Power Conference Teams; Average: .671

Pittsburgh is 4-9 (.308) when allowing 100 or more rushing yards since the 2023 season– T-11th-worst among Power Conference Teams; Average: .470

Pittsburgh is 1-6 (.143) when losing at least one fumble since the 2023 season– T-12th-worst in FBS; Average: .440

Matchup Notes for Clemson vs. Pittsburgh

Pittsburgh has 15 receiving touchdowns in the Red Zone this season — T-5th-most among FBS skill players. Clemson’s defense has allowed 10 receiving touchdowns in the Red Zone this season — T-4th-most among ACC defenses.

Pittsburgh’s RBs has 4 receiving touchdowns in the Red Zone this season — T-most among FBS RBs. Clemson’s defense has allowed 10 receiving touchdowns in the Red Zone this season — T-4th-most among ACC defenses.

Pittsburgh’s RBs has rushed for 924 yards on 165 carries (5.6 YPC) this season — T-29th-best among FBS RBs. Clemson’s defense have allowed 4.4 YPC this season — T-3rd-worst among ACC defenses.

Clemson’s QBs has thrown for 2,411 passing yards in 9 games (267.9 YPG) this season — 31st-best among FBS teams. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 4th-worst among ACC defenses.

Clemson’s QBs has thrown for 2,411 passing yards in 9 games (267.9 YPG) this season — 31st-best among FBS teams. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 21st-worst among FBS defenses.

Clemson’s offense has thrown for 2,473 passing yards in 9 games (274.8 YPG) this season — 24th-best among FBS offenses. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 4th-worst among ACC defenses.

Clemson Offensive Stats & Trends

Clemson’s QBs has thrown for 2,411 passing yards in 9 games (267.9 YPG) this season — 31st-best among FBS teams. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 4th-worst among ACC defenses.

Clemson’s QBs has thrown for 2,411 passing yards in 9 games (267.9 YPG) this season — 31st-best among FBS teams. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 21st-worst among FBS defenses.

Clemson’s offense has thrown for 2,473 passing yards in 9 games (274.8 YPG) this season — 24th-best among FBS offenses. Pittsburgh’s defense has allowed 251.7 passing yards per game this season — 4th-worst among ACC defenses.

Clemson RBs have averaged 8.4 yards from scrimmage per touch (185 yards / 22 touches) on 3rd and short this season– 4th-best among FBS Teams; Average: 4.5

Clemson Skill Players have averaged just 9.2 yards per reception (808 yards/88 catches) in the 4th quarter since the 2023 season– 2nd-worst among Power Conference Teams; Average: 12.3

Pittsburgh Offensive Stats & Trends

Pittsburgh RBs have averaged 9.2 yards from scrimmage per touch (619 yards / 67 touches) on 2nd down this season– best among FBS Teams; Average: 5.5

Pittsburgh RBs have averaged 11.5 yards from scrimmage per touch (138 yards / 12 touches) in close and late situations this season– 2nd-best among FBS Teams; Average: 5.4

Pittsburgh Skill Players have caught 9 touchdown passes in the 4th quarter this season– T-most among FBS Teams

Pittsburgh Skill Players have caught 9 touchdown passes in the 4th quarter this season– T-most among Power Conference Teams

Pittsburgh RBs have picked up first downs on 5 receptions in the Red Zone this season– most among FBS Teams

Clemson Tigers Defensive Stats & Trends

Clemson has allowed a Completion Pct of just 12% (1 completions/8 attempts) on 3rd and short this season– best among Power Conference Teams; Average: 60%

Clemson has allowed a Completion Pct of just 53% (377 completions/706 attempts) since the 2023 season– 2nd-best in FBS; Average: 61%

Clemson has allowed a Completion Pct of just 53% (182 completions/344 attempts) in the 1st half since the 2023 season– 2nd-best in FBS; Average: 62%

Clemson has allowed first downs on 38% of rush attempts in close and late situations this season– worst among Power Conference Teams; Average: 21%

Clemson has allowed a Completion Pct of just 40% (10 completions/25 attempts) on 3rd and short since the 2023 season– T-2nd-best in FBS; Average: 62%

Pittsburgh Panthers Defensive Stats & Trends

Pittsburgh has allowed passes of 20+ yards on 24 of 109 attempts (22%) on 3rd and long since the 2023 season– worst among Power Conference Teams; Average: 9%

Pittsburgh has allowed passes of 20+ yards on 24 of 109 attempts (22%) on 3rd and long since the 2023 season– worst in FBS; Average: 9%

Pittsburgh has allowed passes of 20+ yards on 14 of 62 attempts (23%) on 3rd and long this season– worst among Power Conference Teams; Average: 9%

Pittsburgh has allowed passes of 20+ yards on 14 of 62 attempts (23%) on 3rd and long this season– 2nd-worst in FBS; Average: 10%

Pittsburgh allowed passes of 20+ yards on 10 of 47 attempts (21%) on 3rd and long in the 2023 season– T-best in FBS; Average: 9%


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.