Angels vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 21

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Houston Astros' Yordan Alvarez runs up the first base line against the Los Angeles Angels during the fourth inning of a baseball game Sunday, June 4, 2023, in Houston.
(AP Photo/David J. Phillip)
BetMGM Betting @BETMGM May 21, 2024, 11:00 AM
  • The Astros are -210 favorites vs the Angels
  • Angels vs Astros Over / Under today: 8.5 Runs
  • Angels / Astros TV Channel: SCHN | BSW

The Los Angeles Angels (+165) visit Minute Maid Park to take on the Houston Astros (-200) on Tuesday, May 21, 2024. First pitch is scheduled for 8:10pm EDT in Houston, TX.

This season, the Angels are 19-29 against the spread (ATS), while the Astros are 20-28 ATS.

Angels vs Astros Starting Pitchers Today:

  • Angels starting pitcher: Griffin Canning 2-4, 5.25 ERA
  • Astros starting pitcher: Cristian Javier 3-1, 3.23 ERA

Angels vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels+1.5 -115O 8.5 +100+165
Astros -1.5 -105U 8.5 -120-200

Angels vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Tuesday‘s MLB game with 60.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Tuesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Jo Adell has hit the Home Runs Over in 8 of his last 25 games (+30.80 Units / 123% ROI)
  • Taylor Ward has hit the RBIs Over in 15 of his last 24 away games (+15.40 Units / 64% ROI)
  • Kevin Pillar has hit the Runs Over in his last 8 games (+12.70 Units / 159% ROI)
  • Zach Neto has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+10.35 Units / 35% ROI)
  • Zach Neto has hit the Total Bases Over in 22 of his last 30 games (+10.25 Units / 23% ROI)

And here are some favorite MLB player prop bets for Astros players for Tuesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Kyle Tucker has hit the Home Runs Over in 9 of his last 21 games (+20.35 Units / 97% ROI)
  • Yordan Alvarez has hit the Hits Under in 26 of his last 46 games (+19.25 Units / 33% ROI)
  • Yordan Alvarez has hit the RBIs Under in 23 of his last 25 games at home (+19.20 Units / 47% ROI)
  • Kyle Tucker has hit the Total Bases Over in 28 of his last 46 games (+14.45 Units / 30% ROI)
  • Yordan Alvarez has hit the Runs Under in 30 of his last 46 games (+14.20 Units / 27% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 48 games (+9.20 Units / 16% ROI)
  • The Los Angeles Angels have hit the Team Total Over in 29 of their last 47 games (+8.05 Units / 14% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 7 of their last 10 games (+6.40 Units / 61% ROI)
  • The Los Angeles Angels have hit the Game Total Over in 15 of their last 25 games (+6.35 Units / 23% ROI)
  • The Los Angeles Angels have hit the Moneyline in 5 of their last 6 away games (+6.30 Units / 105% ROI)
  • The Houston Astros have hit the Team Total Under in 29 of their last 48 games (+8.95 Units / 17% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 27 games (+6.25 Units / 20% ROI)
  • The Houston Astros have hit the Game Total Under in 18 of their last 31 games (+6.00 Units / 17% ROI)
  • The Houston Astros have hit the Moneyline in 9 of their last 12 games (+4.30 Units / 23% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 7 of their last 9 games (+4.25 Units / 36% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 26-22 against the Run Line (-6.7 Units / -9.23% ROI).

  • 19-29 when betting on the Moneyline for -5.75 Units / -11.65% ROI
  • 26-20 when betting on the total runs Over for +3.8 Units / 7.15% ROI
  • 20-26 when betting on the total runs Under for -8.5 Units / -16.21% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 20-28 against the Run Line (-7.65 Units / -13.33% ROI).

  • 21-27 when betting on the Moneyline for -14.55 Units / -21.44% ROI
  • 19-26 when betting on the total runs Over for -9.25 Units / -17.62% ROI
  • 26-19 when betting on the total runs Under for +5.15 Units / 9.69% ROI

Astros vs Angels Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +240 0.5 -300
Kyle Tucker (HOU) 0.5 +340 0.5 -450
Logan O'Hoppe (LAA) 0.5 +375 0.5 -550
Yainer Diaz (HOU) 0.5 +425 0.5 -600
Taylor Ward (LAA) 0.5 +450 0.5 -650

Astros vs Angels Total Hits Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 -275 0.5 +200
Kyle Tucker (HOU) 0.5 -250 0.5 +180
Alex Bregman (HOU) 0.5 -250 0.5 +195
Nolan Schanuel (LAA) 0.5 -210 0.5 +155
Jake Meyers (HOU) 0.5 -190 0.5 +145

Astros vs Angels RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +110 0.5 -145
Alex Bregman (HOU) 0.5 +125 0.5 -165
Yainer Diaz (HOU) 0.5 +140 0.5 -190
Kyle Tucker (HOU) 0.5 +150 0.5 -200
Logan O'Hoppe (LAA) 0.5 +155 0.5 -210

Astros vs Angels Strikeout Prop Bets Today

Over Under
Cristian Javier (HOU) 5.5 +115 5.5 -150
Griffin Canning (LAA) 4.5 +130 4.5 -175

Griffin Canning has allowed an OPS of .951 (81 PA’s) when going through the lineup the first time in a game this season — highest among in MLB; League Avg: .659 — second Percentile.

Griffin Canning has allowed a slugging percentage of .606 (43 Total Bases / 71 ABs) when going through the lineup the first time in a game this season — 2nd highest among qualified SPs in MLB; League Avg: .379 — second Percentile.

Griffin Canning has allowed an OPS of .951 (81 PA’s) when going through the lineup the first time in a game this season — 4th highest among qualified SPs in MLB; League Avg: .672 — fourth Percentile.

Griffin Canning has a strikeout rate of just 8% (3 SO in 37 PAs) in PAs ending on elevated fastballs this season — 4th lowest among qualified SPs in MLB; League Avg: 24% — fifth Percentile.

Astros Starting Pitcher Stats & Trends

Right-handed hitters have a groundball rate of just 21% (51/238) against Cristian Javier since last season — lowest in MLB among starting pitchers with at least 82 total IP; League Avg: 43% — 0 Percentile.

Hitters have swung at 38% of Cristian Javier’s non-fastballs (574/1,508) since last season — lowest in MLB among starting pitchers with at least 82 total IP; League Avg: 48% — first Percentile.

Opponents have a groundball rate of just 26% (144/546) against Cristian Javier since last season — lowest in MLB among starting pitchers with at least 82 total IP; League Avg: 43% — 0 Percentile.

Hitters have swung at 39% of Cristian Javier’s non-fastballs (986/2,532) since the 2022 season — lowest in MLB among starting pitchers with at least 147 total IP; League Avg: 48% — first Percentile.

Angels Keys to the Game vs. the Astros

The Angels are just 75-15 (.833) when leading entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .898.

The Angels are just 64-31 (.674) when scoring 5 or more runs since the 2023 season — 2nd lowest in MLB; League Avg: .789.

The Angels are just 145-14 (.912) when leading entering the 9th inning since the 2022 season — 2nd lowest in MLB; League Avg: .950.

The Angels are just 9-162 (.053) when trailing entering the 8th inning since the 2022 season — 2nd lowest in MLB; League Avg: .094.

Astros Keys to the Game vs. the Angels

The Astros are 154-22 (.875) when scoring 5 or more runs since the 2022 season — best in MLB; League Avg: .795.

The Astros are 175-18 (.907) when leading entering the 7th inning since the 2022 season — 4th best in MLB; League Avg: .867.

The Astros are 45-29 (.608) after a road loss since the 2022 season — 2nd best in MLB; League Avg: .461.

The Astros are 64-44 (.593) after a road win since the 2022 season — 2nd best in MLB; League Avg: .488.

Angels hitters have an OBP of just .278 (1,089 PA’s) against pitchers who have thrown at least 80 pitches in a game since the 2022 season — lowest in MLB; League Avg: .318.

Angels hitters have an OPS of just .644 (1,089 PA’s) against pitchers who have thrown at least 80 pitches in a game since the 2022 season — lowest in MLB; League Avg: .738.

The Angels are batting .281 against LHP this season — 2nd best in MLB; League Avg: .244.

Angels hitters have an OBP of .340 (360 PA’s) against LHP this season — tied for 4th best in MLB; League Avg: .313.

Astros hitters have just 740 strikeouts in 4,201 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

Astros hitters are slugging .459 against LHP since the 2022 season — 2nd best in MLB; League Avg: .406.

The Astros are batting .267 against LHP since the 2022 season — 2nd best in MLB; League Avg: .249.

Astros hitters have an OPS of .795 (4,201 PA’s) against LHP since the 2022 season — 2nd best in MLB; League Avg: .724.

Angels pitchers have an ERA of 5.59 (198.0 IP) at home this season — highest in MLB; League Avg: 3.85.

The Angels have allowed 5.91 runs per game (130/22) at home this season — 2nd highest in MLB; League Avg: 4.33.

Angels pitchers have walked 196 of 1,863 batters (10%) when facing the leadoff batter in the inning since last season — 2nd highest in MLB; League Avg: 8%.

Angels pitchers have walked 318 of 3,303 batters (10%) when facing the leadoff batter in the inning since the 2022 season — highest in MLB; League Avg: 8%.

Astros pitchers have thrown at least two strikes in their first three pitches to 58% of opposing batters this season — 2nd lowest in MLB; League Avg: 64%.

Opponents have a miss rate of 27% against Astros pitchers since last season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have walked 190 of 1,848 batters (10%) this season — 2nd highest in MLB; League Avg: 8%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros vs. Angels Injuries Tonight That May Affect Prop Bets 

  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL
  • Michael Stefanic (Los Angeles Angels): Quadriceps, 10-Day IL
  • Sam Bachman (Los Angeles Angels): Shoulder, 60-Day IL
  • Mickey Moniak (Los Angeles Angels): Illness, Day-To-Day
  • Austin Warren (Los Angeles Angels): Elbow, 60-Day IL
  • Robert Stephenson (Los Angeles Angels): Shoulder, 15-Day IL
  • Aaron Loup (Los Angeles Angels): Shoulder, Out
  • Randal Grichuk (Los Angeles Angels): Ankle, 10-Day IL
  • Kelvin Caceres (Los Angeles Angels): Lat, 60-Day IL
  • Jose Quijada (Los Angeles Angels): Elbow, 60-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.