Angels vs Athletics Prediction, Odds & Player Prop Bets Today – MLB, May 22

Oakland Athletics' Shea Langeliers runs up the first base line against the Houston Astros during the third inning of a baseball game Friday, May 19, 2023, in Houston.
(AP Photo/David J. Phillip)
  • The Athletics are -130 favorites vs the Angels
  • Angels vs Athletics Over / Under today: 10.5 Runs
  • Angels / Athletics TV Channel: FDW | NSCA

The Los Angeles Angels (+110) visit Sutter Health Park to take on the Oakland Athletics (-130) on Thursday, May 22, 2025. First pitch is scheduled for 3:35pm EDT in Sacramento, CA.

This season, the Angels are 23-25 against the spread (ATS), while the Athletics are ATS.

Angels vs Athletics Starting Pitchers Today:

  • Angels starting pitcher: Tyler Anderson 2-1, 3.06 ERA
  • Athletics starting pitcher: Luis Severino 1-4, 4.20 ERA

Angels vs. Athletics Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels+1.5 -190O 10.5 -110+110
Athletics -1.5 +154U 10.5 -110-130

Angels vs Athletics Prediction for Today’s Game

Based on recent trends the model predicts the Athletics will win Thursday‘s MLB game with 57.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Thursday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

And here are some favorite MLB player prop bets for Athletics players for Thursday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Best Bets Today:

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 22-26 against the Run Line (-12 Units / -18.18% ROI).

  • 23-25 when betting on the Moneyline for +4.05 Units / 7.78% ROI
  • 27-20 when betting on the total runs Over for +5.07 Units / 9.56% ROI
  • 20-27 when betting on the total runs Under for -9.37 Units / -17.82% ROI

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Athletics vs Angels Home Run Prop Bets Today

Over Under
Brent Rooker (ATH) 0.5 +240 0.5 -300
Shea Langeliers (ATH) 0.5 +310 0.5 -400
Tyler Soderstrom (ATH) 0.5 +333 0.5 -450
Zach Neto (LAA) 0.5 +333 0.5 -450
Jorge Soler (LAA) 0.5 +340 0.5 -450

Athletics vs Angels Total Hits Prop Bets Today

Over Under
Brent Rooker (ATH) 0.5 -275 0.5 +200
Nolan Schanuel (LAA) 0.5 -250 0.5 +190
Shea Langeliers (ATH) 0.5 -250 0.5 +190
Zach Neto (LAA) 0.5 -250 0.5 +185
Taylor Ward (LAA) 0.5 -250 0.5 +185

Athletics vs Angels RBI Prop Bets Today

Over Under
Brent Rooker (ATH) 0.5 +115 0.5 -150
Shea Langeliers (ATH) 0.5 +135 0.5 -175
Taylor Ward (LAA) 0.5 +145 0.5 -190
Tyler Soderstrom (ATH) 0.5 +150 0.5 -200
Zach Neto (LAA) 0.5 +160 0.5 -220

Athletics vs Angels Strikeout Prop Bets Today

Over Under
Luis Severino (ATH) 5.5 +115 5.5 -150

Tyler Anderson has a first-pitch in-zone of just 46% (94/206) this season — lowest among qualified SPs in MLB; League Avg: 56% — first Percentile.

Tyler Anderson has allowed a slugging percentage of .632 (48 Total Bases / 76 ABs) when going through the lineup the first time in a game this season — highest among qualified SPs in MLB; League Avg: .371 — first Percentile.

Tyler Anderson threw his changeup 32% of the time (199/629) on the first pitch of at-bats in 2023 — highest in MLB among starting pitchers with at least 64 total CH; League Avg: 10% — 100th Percentile.

Tyler Anderson has thrown his changeup 42% of the time (262/626) against right-handed batters this season — highest among qualified SPs in MLB; League Avg: 14% — 100th Percentile.

Athletics Starting Pitcher Stats & Trends

Luis Severino has allowed an OBP of .342 (365 PA’s) when going through the lineup the second time in a game since last season — 2nd highest among qualified SPs in MLB; League Avg: .289 — fourth Percentile.

Luis Severino has thrown inside pitches 45% of the time (230/508) vs left-handed batters this season — highest among among AL Starters; League Avg: 30% — 100th Percentile.

Luis Severino located 40% of his pitches inside (800/2,025) in non-two strike counts in the 2024 season — 3rd highest among qualified SPs in MLB; League Avg: 30% — 96th Percentile.

Luis Severino located 42% of his pitches inside (319/761) on the first pitch of at-bats in the 2024 season — 2nd highest among qualified SPs in MLB; League Avg: 29% — 98th Percentile.

Angels Keys to the Game vs. the Athletics

The Angels were just 39-59 (.398) after a loss in the 2024 season — 2nd lowest in MLB; League Avg: .504.

The Angels were just 54-6 (.900) when leading entering the 9th inning in the 2024 season — 2nd lowest in MLB; League Avg: .949.

The Angels are 3-23 (.115) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .042.

The Angels are just 119-21 (.850) when leading entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .901.

Athletics Keys to the Game vs. the Angels

The Athletics are just 72-114 (.387) at home since the 2023 season — 2nd lowest in MLB; League Avg: .526.

The Athletics are just 85-145 (.370) after a loss since the 2023 season — 3rd lowest in MLB; League Avg: .494.

The Athletics are just 8-16 (.333) at home this season — 2nd lowest in MLB; League Avg: .562.

The Athletics are just 16-2 (.889) when leading entering the 9th inning this season — 3rd lowest in MLB; League Avg: .957.

Opponents have used a defensive shift against the Angels on 1% of their plate appearances this season — highest in MLB; League Avg: 0%.. *

Angels hitters have an OBP of just .201 (969 PA’s) with two-strikes this season — lowest in MLB; League Avg: .248.

Angels hitters have struck out in just 8% of it’s PA’s in lefty-lefty matchups this season — best in MLB; League Avg: 25%.

Angels hitters have an OBP of just .254 (287 PA’s) against LHP this season — lowest in MLB; League Avg: .309.

The Athletics batted just .200 with two outs in 2023 — lowest in MLB; League Avg: .237.

The Athletics batted just .223 in 2023 — lowest in MLB; League Avg: .248.

Athletics hitters are averaging just 3.69 pitches per plate appearance against RHP this season — lowest in MLB; League Avg: 3.89.

Athletics hitters are averaging just 3.67 pitches per plate appearance this season — lowest in MLB; League Avg: 3.89.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2023 season — highest in MLB; League Avg: 8%.

Angels pitchers walked 150 of 1,434 batters (10%) when facing the leadoff batter in the inning in 2023 — highest in MLB; League Avg: 8%.

Angels pitchers have a strikeout rate of just 20% since last season — 2nd lowest in MLB; League Avg: 22%.

Angels pitchers walked 135 of 1,436 batters (9%) when facing the leadoff batter in the inning in the 2024 season — highest in MLB; League Avg: 7%.

Opponents had a groundball rate of just 38% against Athletics pitchers in 2023 — lowest in MLB; League Avg: 43%.

Athletics pitchers had an ERA of 6.09 (676.2 IP) on the road in 2023 — highest in MLB; League Avg: 4.44.

Athletics pitchers walked 694 of 6,384 batters (11%) in 2023 — highest in MLB; League Avg: 9%.

Opponents have a groundball rate of just 39% against Athletics pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.