Angels vs Padres Prediction, Odds & Player Prop Bets Today – MLB, May 14

(AP Photo/Derrick Tuskan)
  • The Padres are -190 favorites vs the Angels
  • Angels vs Padres Over / Under today: 9 Runs
  • Angels / Padres TV Channel: FDW | PDTV

The Los Angeles Angels (+155) visit Petco Park to take on the San Diego Padres (-190) on Wednesday, May 14, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA, CA.

This season, the Angels are 17-24 against the spread (ATS), while the Padres are 25-16 ATS.

Angels vs Padres Starting Pitchers Today:

  • Angels starting pitcher: Kyle Hendricks 1-4, 5.40 ERA
  • Padres starting pitcher: Randy Vasquez 2-3, 3.79 ERA

Angels vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels+1.5 -135O 9 -120+155
Padres -1.5 +110U 9 +100-190

Angels vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 61.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Zach Neto has hit the Home Runs Over in 3 of his last 6 away games (+13.40 Units / 223% ROI)
  • Taylor Ward has hit the Hits Under in 16 of his last 25 games (+12.60 Units / 45% ROI)
  • Taylor Ward has hit the Singles Under in 20 of his last 25 games (+12.55 Units / 35% ROI)
  • Taylor Ward has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+10.65 Units / 35% ROI)
  • Nolan Schanuel has hit the Runs Over in 11 of his last 20 away games (+9.15 Units / 46% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Elias Diaz has hit the Home Runs Over in 3 of his last 10 games (+20.40 Units / 204% ROI)
  • Fernando Tatis Jr. has hit the Hits Runs and RBIs Over in 19 of his last 25 games at home (+12.45 Units / 39% ROI)
  • Luis Arraez has hit the Total Bases Under in 20 of his last 25 games at home (+11.90 Units / 28% ROI)
  • Randy Vasquez has hit the Strikeouts Under in 16 of his last 20 games (+11.65 Units / 42% ROI)
  • Jake Cronenworth has hit the Singles Under in 19 of his last 25 games (+10.80 Units / 29% ROI)
  • The Los Angeles Angels have hit the Game Total Over in 11 of their last 14 games (+7.62 Units / 50% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 18 of their last 29 games (+5.59 Units / 17% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 16 games (+5.58 Units / 29% ROI)
  • The Los Angeles Angels have hit the Moneyline in 5 of their last 10 games (+1.70 Units / 17% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 5 of their last 12 games (+1.20 Units / 10% ROI)
  • The San Diego Padres have covered the Run Line in 14 of their last 18 games at home (+12.10 Units / 57% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 14 of their last 18 games at home (+9.60 Units / 44% ROI)
  • The San Diego Padres have hit the Moneyline in 15 of their last 20 games at home (+8.20 Units / 27% ROI)
  • The San Diego Padres have hit the Team Total Over in 14 of their last 20 games at home (+7.70 Units / 33% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 13 of their last 17 games at home (+7.70 Units / 28% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 16-25 against the Run Line (-17.25 Units / -30.13% ROI).

  • 17-24 when betting on the Moneyline for -5.45 Units / -12.1% ROI
  • 23-17 when betting on the total runs Over for +4.47 Units / 9.89% ROI
  • 17-23 when betting on the total runs Under for -8.02 Units / -17.81% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 25-16 against the Run Line (+6.25 Units / 11.19% ROI).

  • 26-15 when betting on the Moneyline for +7.3 Units / 12.81% ROI
  • 19-21 when betting on the total runs Over for -3.45 Units / -7.82% ROI
  • 21-19 when betting on the total runs Under for -0.45 Units / -0.97% ROI

Padres vs Angels Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +240 0.5 -300
Manny Machado (SD) 0.5 +375 0.5 -500
Jackson Merrill (SD) 0.5 +400 0.5 -550
Zach Neto (LAA) 0.5 +475 0.5 -650
Jorge Soler (LAA) 0.5 +475 0.5 -650

Padres vs Angels Total Hits Prop Bets Today

Over Under
Nolan Schanuel (LAA) 0.5 -250 0.5 +190
Yoan Moncada (LAA) 0.5 -220 0.5 +165
Luis Rengifo (LAA) 0.5 -220 0.5 +165
Gavin Sheets (SD) 0.5 -210 0.5 +160
Zach Neto (LAA) 0.5 -190 0.5 +145

Padres vs Angels RBI Prop Bets Today

Over Under
Jackson Merrill (SD) 0.5 +120 0.5 -160
Fernando Tatis Jr. (SD) 0.5 +130 0.5 -165
Manny Machado (SD) 0.5 +140 0.5 -185
Gavin Sheets (SD) 0.5 +160 0.5 -210
Jorge Soler (LAA) 0.5 +175 0.5 -235

Kyle Hendricks has averaged 87.6 MPH on fastballs in the 2024 season — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 93.6 — 0 Percentile.

Kyle Hendricks located 73% of his pitches away (827/1,135) vs left-handed batters in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 45% — 100th Percentile.

Kyle Hendricks threw his changeup 66% of the time (376/571) with two-strikes in 2023 — highest in MLB among starting pitchers with at least 64 total CH; League Avg: 17% — 100th Percentile.

Kyle Hendricks has located his pitches away 68% of the time (1,681/2,487) vs left-handed batters since the 2023 season — highest in MLB among starting pitchers with at least 145 total IP; League Avg: 45% — 100th Percentile.

Padres Starting Pitcher Stats & Trends

Randy Vasquez has struck out just 7% (21/290) of left-handed batters he faced since last season — lowest in MLB among starting pitchers with at least 80 total IP; League Avg: 22% — 0 Percentile.

Randy Vasquez has struck out just 5% (5/92) of left-handed batters he faced this season — lowest in MLB among starting pitchers with at least 15 total IP; League Avg: 21% — first Percentile.

Left-handed hitters had a line drive rate of 34% (56/163) against Randy Vasquez in the 2024 season — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 24% — first Percentile.

Randy Vasquez has a strikeout rate of just 28% (80 SO in 287 PAs) with two-strikes since last season — lowest in MLB among starting pitchers with at least 80 total IP; League Avg: 42% — 0 Percentile.

Angels Keys to the Game vs. the Padres

The Angels were just 39-59 (.398) after a loss in the 2024 season — 2nd lowest in MLB; League Avg: .504.

The Angels were just 11-37 (.229) when their opponents score in the first inning in the 2024 season — 2nd lowest in MLB; League Avg: .359.

The Angels are just 8-2 (.800) when leading entering the 8th inning this season — 3rd lowest in MLB; League Avg: .915.

The Angels are just 127-13 (.907) when leading entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .949.

Padres Keys to the Game vs. the Angels

The Padres are 4-10 (.286) when trailing entering the 7th inning this season — 2nd best in MLB; League Avg: .117.

The Padres are 3-12 (.200) when trailing entering the 8th inning this season — best in MLB; League Avg: .083.

The Padres were 93-69 (.574) in the 2024 season — tied for 4th best in MLB; League Avg: .500.

The Padres are 119-84 (.586) since last season — tied for 2nd best in MLB; League Avg: .500.

Angels hitters have an OBP of just .194 (811 PA’s) with two-strikes this season — lowest in MLB; League Avg: .249.

Angels hitters have an OBP of just .283 (1,266 PA’s) against RHP this season — lowest in MLB; League Avg: .318.

Angels hitters have struck out in 29% of it’s PA’s this month (12 game{NumGameSuffix}) — highest in MLB; League Avg: 22%.

Angels hitters have drawn walks in 3% of its PA’s against LHP this season — lowest in MLB; League Avg: 9%.

The Padres are batting .294 with two outs this season — best in MLB; League Avg: .235.

Padres hitters have struck out in just 18% of it’s PA’s against LHP since last season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of it’s PA’s this season — best in MLB; League Avg: 22%.

The Padres are batting .202 with two-strikes since last season — best in MLB; League Avg: .168.

Angels pitchers walked 135 of 1,436 batters (9%) when facing the leadoff batter in the inning in the 2024 season — highest in MLB; League Avg: 7%.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2023 season — highest in MLB; League Avg: 8%.

Angels pitchers have a strikeout rate of just 39% with two-strikes since last season — 2nd lowest in MLB; League Avg: 42%.

Angels pitchers had a strikeout rate of just 20% in the 2024 season — 2nd lowest in MLB; League Avg: 23%.

The Padres pitchers have allowed an average Exit Velocity of just 88.2 MPH since the 2023 season (8,839 balls in play) — best in MLB; League Avg: 89.0

The Padres pitchers have allowed their opponents to score first in just 33% of their games since last season — lowest in MLB; League Avg: 50%.

Opponents had a groundball rate of 45% against Padres pitchers in 2023 — 3rd highest in MLB; League Avg: 43%.

Padres pitchers had a strikeout rate of 24% in the 2024 season — 5th best in MLB; League Avg: 23%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.