Angels vs Twins Prediction, Odds & Player Prop Bets Today – MLB, Apr 25

Minnesota Twins third baseman Royce Lewis runs off the field after throwing out Houston Astros' Jeremy Pena at first during the seventh inning of Game 4 of a baseball AL Division Series, Wednesday, Oct. 11, 2023, in Minneapolis.
(AP Photo/Bruce Kluckhohn)
  • The Twins are -190 favorites vs the Angels
  • Angels vs Twins Over / Under today: 8 Runs
  • Angels / Twins TV Channel: FDW | TWTV

The Los Angeles Angels (+165) visit Target Field to take on the Minnesota Twins (-200) on Friday, April 25, 2025. First pitch is scheduled for 8:10pm EDT in Minneapolis, MN, MN.

This season, the Angels are 12-12 against the spread (ATS), while the Twins are 11-14 ATS.

Angels vs Twins Starting Pitchers Today:

  • Angels starting pitcher: Kyle Hendricks 0-2, 4.66 ERA
  • Twins starting pitcher: Pablo Lopez 1-1, 1.59 ERA

Angels vs. Twins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels+1.5 -135O 8 -118+165
Twins -1.5 +110U 8 -102-200

Angels vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Friday‘s MLB game with 63.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Friday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Nolan Schanuel has hit the Home Runs Over in 2 of his last 5 away games (+17.00 Units / 340% ROI)
  • Taylor Ward has hit the Hits Over in 20 of his last 25 away games (+11.60 Units / 22% ROI)
  • Nolan Schanuel has hit the Total Bases Over in 13 of his last 15 away games (+11.30 Units / 47% ROI)
  • Jo Adell has hit the Runs Under in 17 of his last 20 games (+11.20 Units / 29% ROI)
  • Kyren Paris has hit the Hits Runs and RBIs Under in his last 10 games (+10.90 Units / 78% ROI)

And here are some favorite MLB player prop bets for Twins players for Friday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

  • Trevor Larnach has hit the Home Runs Over in 3 of his last 5 games (+14.70 Units / 294% ROI)
  • Pablo Lopez has hit the Walks Allowed Under in 19 of his last 25 games (+10.50 Units / 27% ROI)
  • Ty France has hit the Total Bases Under in 8 of his last 9 games (+8.80 Units / 73% ROI)
  • Ty France has hit the RBIs Over in 6 of his last 9 games at home (+8.20 Units / 91% ROI)
  • Brooks Lee has hit the Runs Under in his last 8 games (+8.00 Units / 47% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 10 of their last 12 games (+7.95 Units / 58% ROI)
  • The Los Angeles Angels have hit the Game Total Under in 7 of their last 9 games (+6.00 Units / 60% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 18 games (+5.60 Units / 25% ROI)
  • The Los Angeles Angels have hit the Moneyline in 12 of their last 23 games (+1.45 Units / 5% ROI)
  • The Minnesota Twins have hit the Game Total Under in 11 of their last 16 games (+6.75 Units / 39% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 16 games (+6.10 Units / 33% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 11 of their last 18 games (+4.55 Units / 21% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 7 of their last 11 games at home (+3.70 Units / 23% ROI)
  • The Minnesota Twins have hit the Team Total Over in 7 of their last 11 games at home (+2.35 Units / 17% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 11-13 against the Run Line (-6 Units / -17.52% ROI).

  • 12-12 when betting on the Moneyline for -0.15 Units / -0.54% ROI
  • 11-12 when betting on the total runs Over for -1.9 Units / -7.16% ROI
  • 12-11 when betting on the total runs Under for +0.4 Units / 1.52% ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 11-14 against the Run Line (-3.2 Units / -10.36% ROI).

  • 9-16 when betting on the Moneyline for -11.1 Units / -32.22% ROI
  • 9-13 when betting on the total runs Over for -5.35 Units / -19.35% ROI
  • 13-9 when betting on the total runs Under for +3.1 Units / 11.33% ROI

Twins vs Angels Home Run Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +320 0.5 -400
Mike Trout (LAA) 0.5 +475 0.5 -650
Jorge Soler (LAA) 0.5 +550 0.5 -800
Trevor Larnach (MIN) 0.5 +600 0.5 -900
Logan O'Hoppe (LAA) 0.5 +650 0.5 -1100

Twins vs Angels Total Hits Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 -220 0.5 +170
Carlos Correa (MIN) 0.5 -220 0.5 +165
Ty France (MIN) 0.5 -210 0.5 +155
Luke Keaschall (MIN) 0.5 -200 0.5 +150
Trevor Larnach (MIN) 0.5 -190 0.5 +145

Twins vs Angels RBI Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +145 0.5 -190
Trevor Larnach (MIN) 0.5 +150 0.5 -200
Ty France (MIN) 0.5 +175 0.5 -225
Luke Keaschall (MIN) 0.5 +200 0.5 -275
Carlos Correa (MIN) 0.5 +200 0.5 -275

Twins vs Angels Strikeout Prop Bets Today

Over Under
Pablo Lopez (MIN) 6.5 +105 6.5 -140
Kyle Hendricks (LAA) 3.5 +130 3.5 -175

Kyle Hendricks has averaged 87.6 MPH on fastballs in the 2024 season — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 93.6 — 0 Percentile.

Kyle Hendricks has a strikeout rate of just 8% (3 SO in 36 PAs) when going through the lineup the first time in a game this month (4 games) — tied for lowest among among AL Starters; League Avg: 24% — third Percentile.

Kyle Hendricks threw his changeup 52% of the time (272/524) with runners in scoring position in 2023 — highest in MLB among starting pitchers with at least 64 total CH; League Avg: 16% — 100th Percentile.

Kyle Hendricks has allowed an average Exit Velocity of just 85.5 MPH since the 2023 season (942 balls in play) — best in MLB among starting pitchers with at least 138 total IP; League Avg: 89.1

Twins Starting Pitcher Stats & Trends

Pablo Lopez has walked 4% of batters when going through the lineup the first time in a game since last season — 3rd best among qualified SPs in MLB; League Avg: 7% — 95th Percentile.

Opposing hitters have a chase rate of 35% (147/421) against Pablo Lopez when he’s behind in the count since the 2023 season — highest in MLB among starting pitchers with at least 138 total IP; League Avg: 25% — 100th Percentile.

Pablo Lopez has walked 5% of batters since last season — tied for 7th best among qualified SPs in MLB; League Avg: 7% — 88th Percentile.

Opponents have a first pitch chase rate of 24% (88/364) against Pablo Lopez since last season — highest among qualified SPs in MLB; League Avg: 17% — 100th Percentile.

Angels Keys to the Game vs. the Twins

The Angels were just 11-37 (.229) when their opponents score in the first inning in the 2024 season — 2nd lowest in MLB; League Avg: .359.

The Angels were just 32-49 (.395) at home in the 2024 season — 3rd lowest in MLB; League Avg: .521.

The Angels are just 37-53 (.411) at home since last season — 3rd lowest in MLB; League Avg: .533.

The Angels are just 124-13 (.905) when leading entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .950.

Twins Keys to the Game vs. the Angels

The Twins are just 9-3 (.750) when leading entering the 7th inning this season — tied for 3rd lowest in MLB; League Avg: .878.

The Twins are just 0-10 (.000) when allowing 5 or more runs this season — tied for lowest in MLB; League Avg: .170.

The Twins are just 9-15 (.375) when allowing 5 or more extra base hits this season — 3rd lowest in MLB; League Avg: .529.

The Twins are just 1-83 (.012) when trailing entering the 9th inning since last season — 2nd lowest in MLB; League Avg: .049.

Angels hitters have an OBP of just .232 (156 PA’s) against LHP this season — 2nd lowest in MLB; League Avg: .307.

Angels hitters have drawn walks in 3% of its PA’s against LHP this season — lowest in MLB; League Avg: 9%.

Angels hitters have struck out in 32% of it’s PA’s over the last 14 days — highest in MLB; League Avg: 22%.

Angels hitters have an OBP of just .270 (315 PA’s) at home this season — 2nd lowest in MLB; League Avg: .327.

Twins hitters have struck out in 33% of it’s PA’s against LHP this season — highest in MLB; League Avg: 24%.

The Twins batted just .150 with two-strikes in the 2023 season — lowest in MLB; League Avg: .172.

The Twins are batting just .157 against LHP this season — lowest in MLB; League Avg: .232.

Twins hitters have an OBP of just .222 (180 PA’s) against LHP this season — lowest in MLB; League Avg: .307.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2023 season — highest in MLB; League Avg: 8%.

Angels pitchers walked 135 of 1,436 batters (9%) when facing the leadoff batter in the inning in the 2024 season — highest in MLB; League Avg: 7%.

Angels pitchers have a strikeout rate of just 20% since last season — 2nd lowest in MLB; League Avg: 23%.

Angels pitchers have walked 10% of batters since last season — 2nd highest in MLB; League Avg: 8%.

Twins pitchers have walked 7% of batters when facing the leadoff batter in the inning since the 2023 season — tied for 2nd best in MLB; League Avg: 8%.

Opponents have a groundball rate of just 40% against Twins pitchers since last season — 3rd lowest in MLB; League Avg: 43%.

Twins pitchers walked 443 of 6,028 batters (7%) in 2023 — tied for 3rd best in MLB; League Avg: 9%.

Opponents have a groundball rate of just 41% against Twins pitchers since the 2023 season — 4th lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.