Astros vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 14

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Astros are -110 favorites vs the Cardinals
  • Astros vs Cardinals Over / Under today: 7.5 Runs
  • Astros / Cardinals TV Channel: FDMW | SCHN

The Houston Astros (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Monday, April 14, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO.

This season, the Astros are 7-8 against the spread (ATS), while the Cardinals are 8-7 ATS.

Astros vs Cardinals Starting Pitchers Today:

  • Astros starting pitcher: Framber Valdez 1-1, 2.55 ERA
  • Cardinals starting pitcher: Sonny Gray 2-0, 4.50 ERA

Astros vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Astros-1.5 +155O 7.5 -125-110
Cardinals +1.5 -190U 7.5 +105-110

Astros vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Monday‘s MLB game with 53.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Astros players for Monday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

  • Isaac Paredes has hit the Home Runs Over in 3 of his last 4 games (+15.40 Units / 385% ROI)
  • Isaac Paredes has hit the Singles Over in 18 of his last 25 away games (+14.30 Units / 56% ROI)
  • Yainer Diaz has hit the Total Bases Under in 16 of his last 20 away games (+11.85 Units / 43% ROI)
  • Isaac Paredes has hit the Hits Over in 19 of his last 25 away games (+10.95 Units / 27% ROI)
  • Yordan Alvarez has hit the Runs Under in 13 of his last 15 games (+10.85 Units / 60% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Monday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Jordan Walker has hit the Home Runs Over in 2 of his last 5 games at home (+11.50 Units / 230% ROI)
  • Brendan Donovan has hit the Hits Over in his last 8 games (+8.95 Units / 55% ROI)
  • Nolan Arenado has hit the RBIs Over in 6 of his last 9 games at home (+7.90 Units / 88% ROI)
  • Jordan Walker has hit the Singles Over in 7 of his last 8 games at home (+7.15 Units / 89% ROI)
  • Nolan Arenado has hit the Total Bases Under in 6 of his last 7 games (+6.55 Units / 80% ROI)
  • The Houston Astros have hit the Game Total Under in 92 of their last 162 games (+21.10 Units / 12% ROI)
  • The Houston Astros have covered the Run Line in 83 of their last 162 games (+4.80 Units / 2% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 37 of their last 79 away games (+3.70 Units / 4% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 44 of their last 79 away games (+3.00 Units / 3% ROI)
  • The Houston Astros have hit the Moneyline in 43 of their last 79 away games (+1.00 Units / 1% ROI)
  • The St. Louis Cardinals have covered the Run Line in 43 of their last 84 games at home (+4.40 Units / 4% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 6 of their last 9 games at home (+3.05 Units / 31% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 5 of their last 9 games at home (+2.95 Units / 27% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 6 of their last 9 games at home (+2.85 Units / 26% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 7-8 against the Run Line (-0.85 Units / -4.22% ROI).

  • 7-8 when betting on the Moneyline for -2.85 Units / -15.32% ROI
  • 6-7 when betting on the total runs Over for -1.9 Units / -11.38% ROI
  • 7-6 when betting on the total runs Under for +0.35 Units / 2.15% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 8-7 against the Run Line (-0.4 Units / -1.83% ROI).

  • 7-8 when betting on the Moneyline for -1.65 Units / -9.65% ROI
  • 9-5 when betting on the total runs Over for +3.45 Units / 21.04% ROI
  • 5-9 when betting on the total runs Under for -5.05 Units / -30.42% ROI

Cardinals vs Astros Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +360 0.5 -500
Christian Walker (HOU) 0.5 +500 0.5 -700
Willson Contreras (STL) 0.5 +700 0.5 -1200
Luken Baker (STL) 0.5 +750 0.5 -1200
Yainer Diaz (HOU) 0.5 +750 0.5 -1200

Cardinals vs Astros Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -225 0.5 +175
Jose Altuve (HOU) 0.5 -225 0.5 +170
Yordan Alvarez (HOU) 0.5 -210 0.5 +155
Jeremy Pena (HOU) 0.5 -210 0.5 +155
Nolan Arenado (STL) 0.5 -185 0.5 +140

Cardinals vs Astros RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +165 0.5 -220
Yainer Diaz (HOU) 0.5 +180 0.5 -250
Nolan Arenado (STL) 0.5 +190 0.5 -250
Christian Walker (HOU) 0.5 +190 0.5 -250
Jeremy Pena (HOU) 0.5 +210 0.5 -295

Cardinals vs Astros Strikeout Prop Bets Today

Over Under
Sonny Gray (STL) 5.5 -140 5.5 +105
Framber Valdez (HOU) 5.5 -140 5.5 +105

7 of Framber Valdez’s breaking pitch strikeouts are backdoor this season — most among qualified SPs in MLB; League Avg: nan — 100th Percentile.

Opponents had a groundball rate of 61% (291/473) against Framber Valdez in the 2024 season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Framber Valdez located 42% of his pitches inside (302/710) with two-strikes in the 2024 season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

Opposing hitters had a groundball rate of 67% (77/115) against Framber Valdez when he was behind in the count in the 2024 season — highest among qualified SPs in MLB; League Avg: 40% — 100th Percentile.

Cardinals Starting Pitcher Stats & Trends

Sonny Gray has a strikeout rate of 57% (222 SO in 387 PAs) with two-strikes since last season — best among qualified SPs in MLB; League Avg: 44% — 100th Percentile.

Opponents had a two strike miss rate of 35% (151/426) against Sonny Gray in the 2024 season — best among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Opponents batted just .106 (35-for-329) against Sonny Gray with two-strikes in the 2024 season — best among qualified SPs in MLB; League Avg: .163 — 100th Percentile.

Sonny Gray has allowed an OBP of just .165 (387 PA’s) with two-strikes since last season — 2nd best among qualified SPs in MLB; League Avg: .229 — 98th Percentile.

Astros Keys to the Game vs. the Cardinals

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are just 0-6 (.000) after a win this season — tied for lowest in MLB; League Avg: .479.

The Astros are just 6-13 (.316) when tied entering the 8th inning since last season — 3rd lowest in MLB; League Avg: .500.

The Astros are just 4-5 (.444) at home this season — tied for 5th lowest in MLB; League Avg: .611.

Cardinals Keys to the Game vs. the Astros

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

The Cardinals are just 50-52 (.490) vs bottom 10 scoring offenses since the 2023 season They play the Astros (10th best runs scored) today.

The Cardinals are 29-20 (.592) when tied entering the 7th inning since the 2023 season — 3rd best in MLB; League Avg: .499.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Astros hitters have an OBP of .543 (46 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .324.

The Astros are batting .432 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .247.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters averaged just 3.66 pitches per plate appearance in the 2024 season — lowest in MLB; League Avg: 3.89.

The Cardinals are batting .226 on pitches out of the zone this season — best in MLB; League Avg: .146.

Cardinals hitters have an OPS of .783 (437 PA’s) against RHP this season — 5th best in MLB; League Avg: .701.

Cardinals hitters have an OBP of .369 (354 PA’s) at home this season — tied for best in MLB; League Avg: .325.

Cardinals hitters had 313 extra-base hits out of 991 total hits (just 32%) against RHP in the 2024 season — 3rd lowest in MLB; League Avg: 35%.

Opponents have a miss rate of 30% against Astros pitchers this season — best in MLB; League Avg: 26%.

Astros pitchers have a strikeout rate of 30% this season — best in MLB; League Avg: 23%.

Astros pitchers have a strikeout rate of 32% with runners in scoring position this season — best in MLB; League Avg: 22%.

Astros pitchers have a strikeout rate of 31% this month (11 games) — best in MLB; League Avg: 23%.

The Cardinals have allowed 8.17 runs per game (49/6) on the road this season — highest in MLB; League Avg: 4.64.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have an ERA of 7.08 (54.2 IP) on the road this season — highest in MLB; League Avg: 4.42.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.