Astros vs Nationals Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

Washington Nationals' Luis Garcia hits an RBI single against the Seattle Mariners to score CJ Abrams during the third inning of a baseball game Monday, June 26, 2023, in Seattle.
(AP Photo/Lindsey Wasson)
  • The Astros are -190 favorites vs the Nationals
  • Astros vs Nationals Over / Under today: 9 Runs
  • Astros / Nationals TV Channel: MASN | SCHN | MLBN

The Houston Astros (-190) visit Nationals Park to take on the Washington Nationals (+155) on Sunday, April 21, 2024. First pitch is scheduled for 1:35pm EDT in Washington, DC.

This season, the Astros are 7-15 against the spread (ATS), while the Nationals are 12-8 ATS.

Astros vs Nationals Starting Pitchers Today:

  • Astros starting pitcher: Cristian Javier 2-0, 1.54 ERA
  • Nationals starting pitcher: Mitchell Parker 1-0, 3.60 ERA

Astros vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Astros-1.5 -115O 9 -115-190
Nationals +1.5 -105U 9 -105+155

Astros vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 65.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

  • Cristian Javier has hit the Strikeouts Under in 22 of his last 30 games (+12.70 Units / 33% ROI)
  • Victor Caratini has hit the Total Bases Over in his last 7 away games (+7.50 Units / 74% ROI)
  • Jon Singleton has hit the Hits Over in 9 of his last 10 games (+7.20 Units / 47% ROI)
  • Jon Singleton has hit the Singles Over in 7 of his last 10 games (+7.15 Units / 71% ROI)
  • Victor Caratini has hit the Hits Over in his last 7 away games (+7.00 Units / 53% ROI)

And here are some favorite MLB player prop bets for Nationals players for Sunday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

  • Patrick Corbin has hit the Earned Runs Over in his last 6 games (+6.10 Units / 77% ROI)
  • Patrick Corbin has hit the Pitching Outs Over in 19 of his last 30 games (+5.60 Units / 15% ROI)
  • Jake Irvin has hit the Pitching Outs Over in 8 of his last 11 games (+5.15 Units / 38% ROI)
  • Drew Millas has hit the Runs Under in his last 5 games at home (+5.00 Units / 40% ROI)
  • MacKenzie Gore has hit the Strikeouts Under in 8 of his last 11 games (+4.90 Units / 36% ROI)
  • The Houston Astros have hit the Moneyline in 53 of their last 80 away games (+22.35 Units / 21% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 40 of their last 60 away games (+16.18 Units / 22% ROI)
  • The Houston Astros have covered the Run Line in 40 of their last 62 away games (+15.50 Units / 18% ROI)
  • The Houston Astros have hit the Game Total Over in 37 of their last 61 games (+15.00 Units / 22% ROI)
  • The Houston Astros have hit the Team Total Over in 34 of their last 51 away games (+13.80 Units / 23% ROI)
  • The Washington Nationals have hit the Moneyline in 66 of their last 144 games (+23.45 Units / 16% ROI)
  • The Washington Nationals have hit the Game Total Over in 13 of their last 20 games at home (+6.30 Units / 28% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 4 of their last 6 games (+2.39 Units / 38% ROI)
  • The Washington Nationals have covered the Run Line in 4 of their last 7 games (+1.50 Units / 21% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 8-14 against the Run Line (-4.85 Units / -20.04% ROI).

  • 7-15 when betting on the Moneyline for -11.9 Units / -42.27% ROI
  • 8-12 when betting on the total runs Over for -5 Units / -20.79% ROI
  • 12-8 when betting on the total runs Under for +3.2 Units / 13.14% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 12-8 against the Run Line (+2.65 Units / 10.37% ROI).

  • 9-11 when betting on the Moneyline for +4.5 Units / 22.11% ROI
  • 8-11 when betting on the total runs Over for -4.05 Units / -18.49% ROI
  • 11-8 when betting on the total runs Under for +2.1 Units / 9.5% ROI

Nationals vs Astros Home Run Prop Bets Today

Over Under
Joey Gallo (WAS) 0.5 +280 0.5 -350
Yordan Alvarez (HOU) 0.5 +300 0.5 -375
Kyle Tucker (HOU) 0.5 +425 0.5 -600
Jose Altuve (HOU) 0.5 +450 0.5 -650
Jose Abreu (HOU) 0.5 +500 0.5 -700

Nationals vs Astros Total Hits Prop Bets Today

Over Under
Luis Garcia (WAS) 0.5 -275 0.5 +195
Kyle Tucker (HOU) 0.5 -250 0.5 +180
C.J. Abrams (WAS) 0.5 -250 0.5 +180
Jose Abreu (HOU) 0.5 -210 0.5 +160
Chas McCormick (HOU) 0.5 -210 0.5 +160

Nationals vs Astros RBI Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 +125 0.5 -165
Yordan Alvarez (HOU) 0.5 +130 0.5 -165
Kyle Tucker (HOU) 0.5 +135 0.5 -185
Alex Bregman (HOU) 0.5 +135 0.5 -185
Jeremy Pena (HOU) 0.5 +140 0.5 -185

Nationals vs Astros Strikeout Prop Bets Today

Over Under

Cristian Javier has walked 6 of 36 batters (17%) when going through the lineup the second time in a game this season — tied for 2nd highest among qualified SPs in MLB; League Avg: 8% — fourth Percentile.

Opponents have a groundball rate of just 22% (5/23) against Cristian Javier in two-strike counts this season — lowest among qualified SPs in MLB; League Avg: 46% — first Percentile.

Cristian Javier has walked 6 of 36 batters (17%) when going through the lineup the second time in a game this season — tied for highest among in AL; League Avg: 7% — sixth Percentile.

Right-handed hitters have a groundball rate of just 20% (46/229) against Cristian Javier since last season — lowest in MLB among starting pitchers with at least 72 total IP; League Avg: 43% — 0 Percentile.

Nationals Starting Pitcher Stats & Trends

Mitchell Parker has limited playing time.

Astros Keys to the Game vs. the Nationals

The Astros are 105-66 (.614) on the road since the 2022 season — 2nd best in MLB; League Avg: .476.

The Astros are 62-43 (.590) after a road win since the 2022 season — 2nd best in MLB; League Avg: .492.

The Astros are 96-25 (.793) when they’ve hit 2 or more home runs since the 2022 season — 3rd best in MLB; League Avg: .697.

The Astros are 143-21 (.872) when scoring 5 or more runs since the 2022 season — best in MLB; League Avg: .793.

Nationals Keys to the Game vs. the Astros

The Nationals are just 63-107 (.371) at home since the 2022 season — 2nd lowest in MLB; League Avg: .524.

The Nationals are just 21-39 (.350) after a home win since the 2022 season — lowest in MLB; League Avg: .532.

The Nationals are just 39-78 (.333) after a win as underdogs since the 2022 season — 2nd lowest in MLB; League Avg: .412.

The Nationals are just 42-175 (.194) when scoring 4 or fewer runs since the 2022 season — lowest in MLB; League Avg: .280.

Astros hitters have just 686 strikeouts in 3,906 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

Astros hitters have an OPS of .947 (540 PA’s) in lefty-lefty matchups since last season — best in MLB; League Avg: .690.

Astros hitters have just 1,879 strikeouts in 9,262 PA’s (20%) against RHP since the 2022 season — 3rd best in MLB; League Avg: 23%.

Astros hitters have just 2,565 strikeouts in 13,168 PA’s (20%) since the 2022 season — 2nd best in MLB; League Avg: 23%.

Nationals hitters have put 40% of their swings in play against LHP since last season — 2nd highest in MLB; League Avg: 37%.

The Nationals are batting just .081 on pitches out of the zone this season — lowest in MLB; League Avg: .159.

Nationals hitters have just 799 strikeouts in 4,069 PA’s (20%) against LHP since the 2022 season — 4th best in MLB; League Avg: 22%.

Nationals hitters have an OBP of just .276 (254 PA’s) against LHP this season — tied for 3rd lowest in MLB; League Avg: .323.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have a strikeout rate of 25% since the 2022 season — tied for 2nd best in MLB; League Avg: 23%.

Astros pitchers have a strikeout rate of just 38% with two-strikes this season — 2nd lowest in MLB; League Avg: 42%.

Astros pitchers have won 41% of games in which they have allowed their opponent to score in three different innings on the road since the 2022 season — highest in MLB; League Avg: 26%.

Nationals pitchers have a strikeout rate of just 38% with two-strikes since the 2022 season — tied for lowest in MLB; League Avg: 42%.

Nationals pitchers have a strikeout rate of just 38% with two-strikes since last season — tied for 2nd lowest in MLB; League Avg: 42%.

Nationals pitchers have allowed an OBP of .356 (3,020 PA’s) when facing the leadoff batter in the inning since the 2022 season — highest in MLB; League Avg: .309.

Opponents have a miss rate of just 23% against Nationals pitchers since the 2022 season — 3rd lowest in MLB; League Avg: 26%.

Nationals vs. Astros Injuries Tonight That May Affect Prop Bets 

  • Zach Brzykcy (Washington Nationals): Elbow, Out
  • Stone Garrett (Washington Nationals): Ankle, 10-Day IL
  • Stephen Strasburg (Washington Nationals): Shoulder, 60-Day IL
  • Nick Senzel (Washington Nationals): Thumb, 10-Day IL
  • Mason Thompson (Washington Nationals): Elbow, 60-Day IL
  • Cade Cavalli (Washington Nationals): Elbow, 60-Day IL
  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.