Astros vs Royals Prediction, Odds & Player Prop Bets Today – MLB, Apr 25

Kansas City Royals' Bobby Witt Jr. during a baseball game against the Colorado Rockies in Kansas City, Mo., Saturday, June 3, 2023.
(AP Photo/Colin E. Braley)
  • The Astros are -120 favorites vs the Royals
  • Astros vs Royals Over / Under today: 7.5 Runs
  • Astros / Royals TV Channel: SCHN | FDKC

The Houston Astros (-120) visit Kauffman Stadium to take on the Kansas City Royals (+100) on Friday, April 25, 2025. First pitch is scheduled for 7:40pm EDT in Kansas City, MO, MO.

This season, the Astros are 13-11 against the spread (ATS), while the Royals are 10-16 ATS.

Astros vs Royals Starting Pitchers Today:

  • Astros starting pitcher: Hayden Wesneski 1-1, 3.92 ERA
  • Royals starting pitcher: Seth Lugo 1-3, 3.99 ERA

Astros vs. Royals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Astros-1.5 +145O 8 -120-120
Royals +1.5 -175U 8 +100+100

Astros vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Friday‘s MLB game with 53.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

  • Yainer Diaz has hit the Hits Runs and RBIs Under in 16 of his last 20 away games (+12.35 Units / 52% ROI)
  • Isaac Paredes has hit the Singles Over in 17 of his last 25 away games (+12.10 Units / 47% ROI)
  • Yainer Diaz has hit the Total Bases Under in 19 of his last 25 away games (+11.75 Units / 33% ROI)
  • Yainer Diaz has hit the Runs Under in 14 of his last 15 away games (+11.55 Units / 40% ROI)
  • Jose Altuve has hit the Home Runs Over in 2 of his last 8 away games (+11.00 Units / 138% ROI)

And here are some favorite MLB player prop bets for Royals players for Friday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

  • Michael Massey has hit the Runs Under in 22 of his last 25 games (+16.55 Units / 34% ROI)
  • Michael Massey has hit the Total Bases Under in 19 of his last 25 games at home (+13.50 Units / 37% ROI)
  • Jonathan India has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+10.05 Units / 44% ROI)
  • Kyle Isbel has hit the Home Runs Over in 1 of his last 5 games at home (+10.00 Units / 200% ROI)
  • Vinnie Pasquantino has hit the Hits Under in 13 of his last 25 games (+8.50 Units / 34% ROI)
  • The Houston Astros have covered the Run Line in 12 of their last 16 games (+9.90 Units / 46% ROI)
  • The Houston Astros have hit the Team Total Under in 16 of their last 24 games (+7.35 Units / 27% ROI)
  • The Houston Astros have hit the Game Total Under in 7 of their last 8 games (+5.80 Units / 62% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 5 of their last 6 away games (+4.40 Units / 67% ROI)
  • The Houston Astros have hit the Moneyline in 5 of their last 6 games (+3.80 Units / 51% ROI)
  • The Kansas City Royals have hit the Team Total Under in 18 of their last 26 games (+9.80 Units / 33% ROI)
  • The Kansas City Royals have hit the Game Total Under in 13 of their last 18 games (+8.60 Units / 43% ROI)
  • The Kansas City Royals have hit the Moneyline in 7 of their last 8 games at home (+5.90 Units / 47% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 25 games (+5.00 Units / 18% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 4 of their last 8 games at home (+2.85 Units / 22% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 14-10 against the Run Line (+5.25 Units / 16.36% ROI).

  • 13-11 when betting on the Moneyline for -0.25 Units / -0.84% ROI
  • 8-14 when betting on the total runs Over for -7.25 Units / -27.62% ROI
  • 14-8 when betting on the total runs Under for +5.15 Units / 19.36% ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 10-16 against the Run Line (-10.9 Units / -29.9% ROI).

  • 12-14 when betting on the Moneyline for -2.65 Units / -8.13% ROI
  • 9-16 when betting on the total runs Over for -8.2 Units / -29.08% ROI
  • 16-9 when betting on the total runs Under for +6.1 Units / 21.03% ROI

Royals vs Astros Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +450 0.5 -625
Salvador Perez (KC) 0.5 +500 0.5 -700
Christian Walker (HOU) 0.5 +525 0.5 -750
Bobby Witt Jr. (KC) 0.5 +550 0.5 -800
Vinnie Pasquantino (KC) 0.5 +675 0.5 -1100

Royals vs Astros Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -250 0.5 +185
Jose Altuve (HOU) 0.5 -235 0.5 +175
Jeremy Pena (HOU) 0.5 -235 0.5 +180
Maikel Garcia (KC) 0.5 -210 0.5 +155
Yordan Alvarez (HOU) 0.5 -190 0.5 +145

Royals vs Astros RBI Prop Bets Today

Over Under
Bobby Witt Jr. (KC) 0.5 +175 0.5 -235
Christian Walker (HOU) 0.5 +175 0.5 -235
Salvador Perez (KC) 0.5 +175 0.5 -235
Yordan Alvarez (HOU) 0.5 +180 0.5 -235
Vinnie Pasquantino (KC) 0.5 +180 0.5 -235

Royals vs Astros Strikeout Prop Bets Today

Over Under
Seth Lugo (KC) 3.5 -190 3.5 +140
Hayden Wesneski (HOU) 4.5 +115 4.5 -150

Hayden Wesneski allowed a slugging percentage of .722 (39 Total Bases / 54 ABs) on low fastballs in 2023 — 2nd highest in MLB among starting pitchers with at least 64 total IP; League Avg: .430 — first Percentile.

Hayden Wesneski has not walked any of the 36 batters that they have faced when going through the lineup the second time in a game this month (4 games) — tied for best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Hayden Wesneski has not walked any of the 36 batters that they have faced when going through the lineup the second time in a game this month (4 games) — tied for best among among AL Starters; League Avg: 7% — 100th Percentile.

Hayden Wesneski has walked 2% of right-handed batters this month (4 games) — best among among AL Starters; League Avg: 8% — 100th Percentile.

Royals Starting Pitcher Stats & Trends

Seth Lugo has a first-pitch strike rate of 74% (92/124) this season — highest among among AL Starters; League Avg: 63% — 100th Percentile.

Seth Lugo has located his pitches away 64% of the time (58/91) when behind in the count this season — highest among among AL Starters; League Avg: 44% — 100th Percentile.

Right-handed hitters have a miss rate of just 21% (156/753) against Seth Lugo since last season — 5th lowest among qualified SPs in MLB; League Avg: 27% — 10th Percentile.

Seth Lugo has walked 4% of right-handed batters in the 2024 season — 8th best among qualified SPs in MLB; League Avg: 6% — 87th Percentile.

Astros Keys to the Game vs. the Royals

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are just 1-66 (.015) when trailing entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .049.

The Astros are just 13-23 (.361) when tied entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .500.

The Astros were 50-37 (.575) after a win in the 2024 season — 4th best in MLB; League Avg: .496.

Royals Keys to the Game vs. the Astros

The Royals are just 4-58 (.065) when allowing 5 or more runs since last season — 2nd lowest in MLB; League Avg: .192.

The Royals are just 16-82 (.163) when allowing 2 or more home runs since the 2023 season — lowest in MLB; League Avg: .299.

The Royals were just 4-50 (.074) when they allowed 5 or more runs in the 2024 season — 2nd lowest in MLB; League Avg: .196.

The Royals are 8-0 (1.000) when leading entering the 7th inning this season — tied for best in MLB; League Avg: .878.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

15% of Astros’ hitters plate appearances lasted only one pitch (926/6,107 PA’s) in the 2024 season — highest in MLB; League Avg: 12%.

Astros hitters had an OPS of .809 (1,801 PA’s) against LHP in the 2023 season — 2nd best in MLB; League Avg: .742.

Astros hitters struck out just 327 times in 1,801 PA’s (18%) against LHP in 2023 — tied for best in MLB; League Avg: 23%.

Royals hitters had an OBP of just .280 (2,958 PA’s) on the road in 2023 — lowest in MLB; League Avg: .316.

The Royals are batting just .316 on the first pitch of at-bats since the 2023 season — lowest in MLB; League Avg: .340.

The Royals have won just 47% of games in which they have scored first on the road since the 2023 season — 2nd lowest in MLB; League Avg: 63%.

The Royals have won 100% of games in which they have scored in at least three different innings this season — highest in MLB; League Avg: 72%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 26%.

Opponents had a miss rate of 27% against Astros pitchers in the 2024 season — 2nd best in MLB; League Avg: 25%.

Opponents had a miss rate of 28% against Astros pitchers in 2023 — 3rd best in MLB; League Avg: 26%.

Batters facing the Royals pitchers have struck out in the zone 59% of the time this season — highest in MLB; League Avg: 51%. this season — highest in MLB; League Avg: 51%.

Royals pitchers picked-off 19 runners from first base in 2023 — best in MLB.

Royals pitchers had a strikeout rate of just 21% in 2023 — 5th lowest in MLB; League Avg: 23%.

The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.