Brewers vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 27

St. Louis Cardinals second baseman Nolan Gorman throws out Cincinnati Reds' Elly De La Cruz at first base during the fifth inning of a baseball game, Friday, Sept. 8, 2023, in Cincinnati. (AP Photo/Joshua A. Bickel)
(AP Photo/Joshua A. Bickel)
  • The Brewers are -110 favorites vs the Cardinals
  • Brewers vs Cardinals Over / Under today: 8 Runs
  • Brewers / Cardinals TV Channel: FDWI | FDMX

The Milwaukee Brewers (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Sunday, April 27, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO, MO.

This season, the Brewers are 13-15 against the spread (ATS), while the Cardinals are 13-14 ATS.

Brewers vs Cardinals Starting Pitchers Today:

  • Brewers starting pitcher: Jose Quintana 3-0, 0.96 ERA
  • Cardinals starting pitcher: Erick Fedde 1-2, 3.42 ERA

Brewers vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Brewers-1.5 +140O 8 -110-110
Cardinals +1.5 -170U 8 -110-110

Brewers vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Sunday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Brewers players for Sunday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

  • Rhys Hoskins has hit the Singles Over in 13 of his last 20 games (+14.05 Units / 70% ROI)
  • Jake Bauers has hit the Home Runs Over in 2 of his last 5 away games (+12.50 Units / 250% ROI)
  • William Contreras has hit the Hits Over in 13 of his last 15 games (+10.00 Units / 33% ROI)
  • Rhys Hoskins has hit the Runs Under in 13 of his last 15 away games (+9.60 Units / 34% ROI)
  • Rhys Hoskins has hit the Total Bases Over in 12 of his last 15 games (+8.40 Units / 42% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Erick Fedde has hit the Earned Runs Under in 17 of his last 25 games (+8.80 Units / 29% ROI)
  • Erick Fedde has hit the Strikeouts Under in 7 of his last 9 games (+5.25 Units / 53% ROI)
  • Erick Fedde has hit the Walks Allowed Over in his last 4 games (+4.40 Units / 75% ROI)
  • Erick Fedde has hit the Hits Allowed Under in 12 of his last 20 games (+3.50 Units / 15% ROI)
  • Erick Fedde has hit the Pitching Outs Over in 3 of his last 4 games (+1.90 Units / 41% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 15 of their last 24 games (+12.00 Units / 42% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 17 of their last 24 games (+10.00 Units / 36% ROI)
  • The Milwaukee Brewers have covered the Run Line in 13 of their last 19 games (+5.60 Units / 21% ROI)
  • The Milwaukee Brewers have hit the Game Total Under in 14 of their last 24 games (+5.30 Units / 20% ROI)
  • The Milwaukee Brewers have hit the Team Total Over in 13 of their last 20 games (+4.60 Units / 19% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 11 of their last 14 games at home (+8.00 Units / 47% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 9 of their last 14 games at home (+6.95 Units / 39% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 7 of their last 9 games at home (+5.45 Units / 51% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 16 of their last 27 games (+4.05 Units / 13% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 6 of their last 8 games at home (+3.90 Units / 45% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 14-14 against the Run Line (-2.45 Units / -6.57% ROI).

  • 13-15 when betting on the Moneyline for -2.55 Units / -7.62% ROI
  • 11-15 when betting on the total runs Over for -5.5 Units / -17.83% ROI
  • 15-11 when betting on the total runs Under for +2.95 Units / 9.59% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 13-14 against the Run Line (-5.35 Units / -13.58% ROI).

  • 12-15 when betting on the Moneyline for -3.45 Units / -11.42% ROI
  • 15-11 when betting on the total runs Over for +2.75 Units / 9.23% ROI
  • 11-15 when betting on the total runs Under for -5.55 Units / -18.75% ROI

Cardinals vs Brewers Home Run Prop Bets Today

Over Under
Rhys Hoskins (MIL) 0.5 +525 0.5 -750
Jackson Chourio (MIL) 0.5 +625 0.5 -1000
Jake Bauers (MIL) 0.5 +625 0.5 -1000
Willson Contreras (STL) 0.5 +625 0.5 -1000
William Contreras (MIL) 0.5 +650 0.5 -1100

Cardinals vs Brewers Total Hits Prop Bets Today

Over Under
Christian Yelich (MIL) 0.5 -250 0.5 +185
William Contreras (MIL) 0.5 -250 0.5 +185
Willson Contreras (STL) 0.5 -220 0.5 +165
Nolan Arenado (STL) 0.5 -210 0.5 +160
Sal Frelick (MIL) 0.5 -210 0.5 +160

Cardinals vs Brewers RBI Prop Bets Today

Over Under
William Contreras (MIL) 0.5 +135 0.5 -175
Christian Yelich (MIL) 0.5 +140 0.5 -185
Nolan Arenado (STL) 0.5 +150 0.5 -200
Jackson Chourio (MIL) 0.5 +160 0.5 -210
Rhys Hoskins (MIL) 0.5 +160 0.5 -220

Cardinals vs Brewers Strikeout Prop Bets Today

Over Under
Erick Fedde (STL) 3.5 -165 3.5 +130
Jose Quintana (MIL) 3.5 -140 3.5 +105

Jose Quintana has a strike rate of just 59% (1,437/2,444) against right-handed batters since last season — lowest among qualified SPs in MLB; League Avg: 66% — first Percentile.

Jose Quintana had a strike rate of just 59% (1,306/2,224) against right-handed batters in the 2024 season — lowest among qualified SPs in MLB; League Avg: 66% — first Percentile.

Jose Quintana had a strike rate of just 49% (469/961) when behind in the count in the 2024 season — lowest among qualified SPs in MLB; League Avg: 61% — first Percentile.

Jose Quintana had a strike rate of just 59% (1,676/2,819) in the 2024 season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.

Cardinals Starting Pitcher Stats & Trends

Erick Fedde has a strike rate of just 57% (578/1,013) in two strike counts since last season — lowest among qualified SPs in MLB; League Avg: 64% — first Percentile.

Erick Fedde has a strike rate of just 50% (607/1,214) when ahead in the count since last season — lowest among qualified SPs in MLB; League Avg: 61% — second Percentile.

Erick Fedde had a strike rate of just 50% (539/1,077) when behind in the count in the 2024 season — 2nd lowest among qualified SPs in MLB; League Avg: 61% — third Percentile.

Erick Fedde had a strike rate of just 57% (522/908) in two strike counts in the 2024 season — 2nd lowest among qualified SPs in MLB; League Avg: 65% — third Percentile.

Brewers Keys to the Game vs. the Cardinals

The Brewers are 34-27 (.557) vs the top 10 runs allowed teams since last season They play the Cardinals (18th best runs allowed) today.

The Brewers are just 0-13 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .085.

The Brewers are just 0-11 (.000) when allowing 5 or more runs this season — tied for lowest in MLB; League Avg: .171.

The Brewers are just 0-11 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .116.

Cardinals Keys to the Game vs. the Brewers

The Cardinals are just 53-59 (.473) vs bottom 10 scoring offenses since the 2023 season They play the Brewers (sixth best runs scored) today.

The Cardinals are just 2-11 (.154) on the road this season — 2nd lowest in MLB; League Avg: .394.

The Cardinals are just 0-9 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .085.

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

Brewers hitters had 129 extra-base hits out of 494 total hits (just 26%) with two-strikes in 2023 — lowest in MLB; League Avg: 33%.

Brewers hitters have 62 extra-base hits out of 218 total hits (just 28%) on the first pitch of at-bats since last season — lowest in MLB; League Avg: 37%.

Brewers hitters have a swing rate of just 45% against RHP since last season — lowest in MLB; League Avg: 48%.

Brewers hitters had a groundball batting average of .281 in the 2024 season — best in MLB; League Avg: .249.

The Cardinals are batting .224 on pitches out of the zone this season — best in MLB; League Avg: .147.

The Cardinals are batting .381 on changeups this season — best in MLB; League Avg: .236.

Cardinals hitters are slugging .283 on pitches out of the zone this season — best in MLB; League Avg: .198.

Cardinals hitters have an OBP of .362 (535 PA’s) at home this season — 2nd best in MLB; League Avg: .327.

Batters facing the Brewers pitchers have struck out in the zone 55% of the time since last season — highest in MLB; League Avg: 50%. since last season — highest in MLB; League Avg: 50%.

Opponents have a miss rate of just 24% against Brewers pitchers this season — 5th lowest in MLB; League Avg: 26%.

Batters facing the Brewers pitchers have struck out in the zone 52% of the time since the 2023 season — highest in MLB; League Avg: 49%. since the 2023 season — highest in MLB; League Avg: 49%.

Batters facing the Brewers pitchers have struck out in the zone 57% of the time this season — 2nd highest in MLB; League Avg: 51%. this season — 2nd highest in MLB; League Avg: 51%.

Batters facing the Cardinals pitchers have struck out in the zone 46% of the time since last season — 2nd lowest in MLB; League Avg: 50%. since last season — 2nd lowest in MLB; League Avg: 50%.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have a strikeout rate of just 18% this season — 3rd lowest in MLB; League Avg: 22%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.