Cardinals vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Jun 5

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Houston Astros Alex Bregman (2) and Houston Astros Yuli Gurriel celebrate after Game 2 of baseball's American League Championship Series between the Houston Astros and the New York Yankees, Thursday, Oct. 20, 2022, in Houston. The Houston Astros won 3-2.
(AP Photo/Eric Gay)
BetMGM Betting @BETMGM Jun 05, 2024, 11:02 AM
  • The Astros are -165 favorites vs the Cardinals
  • Cardinals vs Astros Over / Under today: 8.5 Runs
  • Cardinals / Astros TV Channel: SCHN | BSMW | ESPN+ | MLBN

The St. Louis Cardinals (+135) visit Minute Maid Park to take on the Houston Astros (-160) on Wednesday, June 5, 2024. First pitch is scheduled for 2:10pm EDT in Houston, TX.

This season, the Cardinals are 28-31 against the spread (ATS), while the Astros are 26-36 ATS.

Cardinals vs Astros Starting Pitchers Today:

  • Cardinals starting pitcher: Miles Mikolas 3-6, 5.57 ERA
  • Astros starting pitcher: Ronel Blanco 5-1, 2.46 ERA

Cardinals vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -150O 8.5 -105+135
Astros -1.5 +125U 8.5 -115-160

Cardinals vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 57.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Alec Burleson has hit the Home Runs Over in 6 of his last 19 away games (+24.90 Units / 131% ROI)
  • Nolan Gorman has hit the Runs Over in 14 of his last 18 games (+16.30 Units / 90% ROI)
  • Ivan Herrera has hit the Total Bases Over in 11 of his last 13 away games (+9.65 Units / 51% ROI)
  • Nolan Gorman has hit the Hits Runs and RBIs Over in 12 of his last 16 games (+8.05 Units / 40% ROI)
  • Ivan Herrera has hit the Hits Over in 11 of his last 13 away games (+7.65 Units / 35% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Alex Bregman has hit the Home Runs Over in 5 of his last 8 games (+24.50 Units / 306% ROI)
  • Yordan Alvarez has hit the RBIs Under in 36 of his last 47 games (+18.70 Units / 24% ROI)
  • Yordan Alvarez has hit the Runs Under in 30 of his last 44 games (+14.60 Units / 28% ROI)
  • Yordan Alvarez has hit the Hits Runs and RBIs Under in 31 of his last 49 games (+12.25 Units / 21% ROI)
  • Yordan Alvarez has hit the Singles Over in 17 of his last 24 games (+12.05 Units / 49% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 13 of their last 20 games (+5.60 Units / 23% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 6 of their last 9 games (+3.70 Units / 37% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 5 of their last 7 games (+3.40 Units / 44% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 4 of their last 7 games (+0.60 Units / 7% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 3 of their last 7 games (+0.55 Units / 8% ROI)
  • The Houston Astros have hit the Game Total Under in 28 of their last 45 games (+11.40 Units / 23% ROI)
  • The Houston Astros have hit the Team Total Under in 36 of their last 62 games (+8.40 Units / 12% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 15 of their last 23 games (+5.70 Units / 20% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 20 games (+4.80 Units / 20% ROI)
  • The Houston Astros have covered the Run Line in 10 of their last 19 games at home (+3.75 Units / 19% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 28-31 against the Run Line (-6.95 Units / -8.8% ROI).

  • 28-31 when betting on the Moneyline for -6.8 Units / -9.8% ROI
  • 25-29 when betting on the total runs Over for -7 Units / -10.93% ROI
  • 29-25 when betting on the total runs Under for +1.7 Units / 2.67% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 26-36 against the Run Line (-9.6 Units / -13.05% ROI).

  • 28-34 when betting on the Moneyline for -16.95 Units / -19.16% ROI
  • 23-36 when betting on the total runs Over for -16.15 Units / -23.89% ROI
  • 36-23 when betting on the total runs Under for +10.55 Units / 15.31% ROI

Astros vs Cardinals Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +260 0.5 -350
Nolan Gorman (STL) 0.5 +360 0.5 -500
Matt Carpenter (STL) 0.5 +425 0.5 -650
Paul Goldschmidt (STL) 0.5 +475 0.5 -700
Alec Burleson (STL) 0.5 +500 0.5 -700

Astros vs Cardinals Total Hits Prop Bets Today

Over Under
Brendan Donovan (STL) 0.5 -250 0.5 +180
Alec Burleson (STL) 0.5 -250 0.5 +190
Mauricio Dubon (HOU) 0.5 -250 0.5 +175
Jake Meyers (HOU) 0.5 -250 0.5 +175
Victor Caratini (HOU) 0.5 -210 0.5 +155

Astros vs Cardinals RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +120 0.5 -155
Jeremy Pena (HOU) 0.5 +175 0.5 -250
Alex Bregman (HOU) 0.5 +175 0.5 -250
Nolan Gorman (STL) 0.5 +180 0.5 -250
Alec Burleson (STL) 0.5 +180 0.5 -250

Astros vs Cardinals Strikeout Prop Bets Today

Over Under
Miles Mikolas (STL) 3.5 -160 3.5 +120
Ronel Blanco (HOU) 5.5 -135 5.5 +105

Miles Mikolas has allowed a slugging percentage of .560 (79 Total Bases / 141 ABs) on non-fastballs this season — highest among qualified SPs in MLB; League Avg: .342 — first Percentile.

Opponents are hitting .319 (45-for-141) against Miles Mikolas’ non-fastballs this season — 2nd highest among qualified SPs in MLB; League Avg: .212 — second Percentile.

Miles Mikolas has allowed an OPS of .747 (138 PA’s) with two-strikes this season — highest among qualified SPs in MLB; League Avg: .487 — first Percentile.

Opponents are hitting .254 (32-for-126) against Miles Mikolas with two-strikes this season — 2nd highest among qualified SPs in MLB; League Avg: .163 — second Percentile.

Astros Starting Pitcher Stats & Trends

Ronel Blanco has walked 16 of 90 batters (18%) when going through the lineup the first time in a game this season — highest among qualified SPs in MLB; League Avg: 7% — first Percentile.

Opponents are hitting just .188 (18-for-96) against Ronel Blanco in non-two strike counts this season — best among qualified SPs in MLB; League Avg: .313 — 100th Percentile.

Opponents have a miss rate of 41% (30/74) against Ronel Blanco on the first pitch of at-bats this season — 2nd best among qualified SPs in MLB; League Avg: 26% — 98th Percentile.

Opponents have a line drive rate of just 16% (24/151) against Ronel Blanco this season — lowest among qualified SPs in MLB; League Avg: 24% — 100th Percentile.

Cardinals Keys to the Game vs. the Astros

The Cardinals are 29-12 (.707) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.

The Cardinals are just 9-93 (.088) when trailing entering the 7th inning since the 2023 season — 4th lowest in MLB; League Avg: .145.

The Cardinals are just 18-28 (.391) after a win as favorites since the 2023 season — 3rd lowest in MLB; League Avg: .578.

The Cardinals are just 6-104 (.055) when trailing entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .104.

Astros Keys to the Game vs. the Cardinals

The Astros are 97-65 (.599) after a loss since the 2022 season — 4th best in MLB; League Avg: .488.

The Astros are 18-18 (.500) after a loss as underdogs since the 2022 season — 4th best in MLB; League Avg: .412.

The Astros are just 23-88 (.207) when scoring 4 or fewer runs since the 2023 season — 5th lowest in MLB; League Avg: .270.

The Astros are 107-29 (.787) when they’ve hit 2 or more home runs since the 2022 season — 3rd best in MLB; League Avg: .699.

Cardinals hitters have an OPS of just .687 (2,221 PA’s) against LHP since last season — 3rd lowest in MLB; League Avg: .731.

Cardinals hitters have an OBP of just .281 (661 PA’s) against LHP this season — 4th lowest in MLB; League Avg: .313.

The Cardinals are batting just .234 against LHP since last season — 2nd lowest in MLB; League Avg: .252.

The Cardinals are batting just .208 against LHP this season — lowest in MLB; League Avg: .245.

Astros hitters have just 755 strikeouts in 4,328 PA’s (17%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

Astros hitters have just 107 strikeouts in 677 PA’s (16%) against LHP this season — best in MLB; League Avg: 22%.

Astros hitters have just 13 strikeouts in 124 PA’s (10%) against LHP over the last 14 days — best in MLB; League Avg: 21%.

Astros hitters have just 434 strikeouts in 2,478 PA’s (17%) against LHP since last season — best in MLB; League Avg: 22%.

Opponents have a groundball rate of 47% against Cardinals pitchers since the 2022 season — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have a strikeout rate of just 20% since the 2022 season — 3rd lowest in MLB; League Avg: 23%.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes since last season — 3rd lowest in MLB; League Avg: 42%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have thrown at least two strikes in their first three pitches to 60% of opposing batters this season — 2nd lowest in MLB; League Avg: 64%.

Opponents have a groundball rate of just 33% against Astros pitchers over the past seven days (7 games) — lowest in MLB; League Avg: 43%.

Astros pitchers have a strikeout rate of 45% with two-strikes since the 2022 season — 3rd best in MLB; League Avg: 42%.

Astros vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL
  • Dylan Carlson (St. Louis Cardinals): Shoulder, 10-Day IL
  • Keynan Middleton (St. Louis Cardinals): Forearm, 15-Day IL
  • Lars Nootbaar (St. Louis Cardinals): Ribs, 10-Day IL
  • Drew Rom (St. Louis Cardinals): Biceps, 15-Day IL
  • Sonny Gray (St. Louis Cardinals): Hamstring, 15-Day IL
  • Riley O’Brien (St. Louis Cardinals): Forearm, 15-Day IL
  • Tommy Edman (St. Louis Cardinals): Wrist, 10-Day IL
  • Packy Naughton (St. Louis Cardinals): Elbow, Out

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.