Cardinals vs Braves Prediction, Odds & Player Prop Bets Today – MLB, Apr 22

Atlanta Braves' Matt Olson (28) runs to first base in the seventh inning of Game 2 of a baseball NL Division Series against the Philadelphia Phillies, Monday, Oct. 9, 2023, in Atlanta. (AP Photo/Brynn Anderson)
(AP Photo/Brynn Anderson)
  • The Braves are -135 favorites vs the Cardinals
  • Cardinals vs Braves Over / Under today: 8.5 Runs
  • Cardinals / Braves TV Channel: FDMW | FDSO | FDSE

The St. Louis Cardinals (+125) visit Truist Park to take on the Atlanta Braves (-150) on Tuesday, April 22, 2025. First pitch is scheduled for 7:15pm EDT in Atlanta, GA, GA.

This season, the Cardinals are 9-14 against the spread (ATS), while the Braves are 9-13 ATS.

Cardinals vs Braves Starting Pitchers Today:

  • Cardinals starting pitcher: Andre Pallante 2-1, 3.28 ERA
  • Braves starting pitcher: Spencer Strider 0-1, 3.60 ERA

Cardinals vs. Braves Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -160O 9 -120+125
Braves -1.5 +135U 9 +100-150

Cardinals vs Braves Prediction for Today’s Game

Based on recent trends the model predicts the Braves will win Tuesday‘s MLB game with 65.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Brendan Donovan has hit the Hits Over in 13 of his last 15 games (+10.80 Units / 36% ROI)
  • Alec Burleson has hit the Runs Under in his last 9 games (+9.00 Units / 43% ROI)
  • Brendan Donovan has hit the Singles Over in 18 of his last 25 away games (+8.45 Units / 26% ROI)
  • Nolan Arenado has hit the Total Bases Under in 15 of his last 20 away games (+7.75 Units / 26% ROI)
  • Jordan Walker has hit the Hits Runs and RBIs Under in 6 of his last 7 away games (+5.20 Units / 59% ROI)

And here are some favorite MLB player prop bets for Braves players for Tuesday‘s game, looking at profitable historical betting trends:

Best Braves Player Prop Best Bets Today:

  • Ozzie Albies has hit the Home Runs Over in 3 of his last 10 games (+12.00 Units / 120% ROI)
  • Matt Olson has hit the Singles Over in 10 of his last 15 games (+8.65 Units / 58% ROI)
  • Austin Riley has hit the RBIs Over in 6 of his last 9 games at home (+7.10 Units / 79% ROI)
  • Matt Olson has hit the Hits Over in 9 of his last 10 games (+6.95 Units / 37% ROI)
  • Marcell Ozuna has hit the Total Bases Over in 8 of his last 10 games (+6.55 Units / 54% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 14 of their last 23 games (+4.50 Units / 18% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 8 of their last 12 games (+3.70 Units / 28% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 6 of their last 9 games (+2.55 Units / 24% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 5 of their last 13 games (+1.80 Units / 13% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 4 of their last 6 away games (+1.65 Units / 24% ROI)
  • The Atlanta Braves have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 12 games (+8.15 Units / 58% ROI)
  • The Atlanta Braves have hit the Moneyline in their last 5 games at home (+5.00 Units / 58% ROI)
  • The Atlanta Braves have hit the Game Total Over in 6 of their last 9 games (+3.80 Units / 38% ROI)
  • The Atlanta Braves have hit the Team Total Over in 4 of their last 5 games at home (+2.95 Units / 47% ROI)
  • The Atlanta Braves have covered the Run Line in 4 of their last 7 games at home (+2.95 Units / 41% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 12-11 against the Run Line (-2.85 Units / -8.33% ROI).

  • 9-14 when betting on the Moneyline for -5.65 Units / -22.33% ROI
  • 13-9 when betting on the total runs Over for +3 Units / 11.83% ROI
  • 9-13 when betting on the total runs Under for -5.35 Units / -21.19% ROI

Braves Against the Spread (ATS) Record

Against the spread this season, the Braves are 9-13 against the Run Line (-4.4 Units / -16.51% ROI).

  • 9-13 when betting on the Moneyline for -7.6 Units / -24.44% ROI
  • 10-9 when betting on the total runs Over for +0.15 Units / 0.61% ROI
  • 9-10 when betting on the total runs Under for -1.95 Units / -8.11% ROI

Braves vs Cardinals Home Run Prop Bets Today

Over Under
Austin Riley (ATL) 0.5 +425 0.5 -600
Marcell Ozuna (ATL) 0.5 +425 0.5 -600
Matt Olson (ATL) 0.5 +500 0.5 -700
Sean Murphy (ATL) 0.5 +650 0.5 -1000
Jarred Kelenic (ATL) 0.5 +700 0.5 -1200

Braves vs Cardinals Total Hits Prop Bets Today

Over Under
Marcell Ozuna (ATL) 0.5 -250 0.5 +185
Alex Verdugo (ATL) 0.5 -225 0.5 +170
Michael Harris (ATL) 0.5 -210 0.5 +155
Ozzie Albies (ATL) 0.5 -200 0.5 +150
Matt Olson (ATL) 0.5 -200 0.5 +150

Braves vs Cardinals RBI Prop Bets Today

Over Under
Matt Olson (ATL) 0.5 +155 0.5 -200
Marcell Ozuna (ATL) 0.5 +165 0.5 -220
Austin Riley (ATL) 0.5 +170 0.5 -225
Ozzie Albies (ATL) 0.5 +170 0.5 -220
Sean Murphy (ATL) 0.5 +190 0.5 -250

Braves vs Cardinals Strikeout Prop Bets Today

Over Under
Andre Pallante (STL) 3.5 -150 3.5 +115

Opponents had a groundball rate of 77% (173/226) against Andre Pallante in 2023 — highest among qualified RPs in MLB; League Avg: 45% — 100th Percentile.

Left-handed hitters had a groundball rate of 77% (102/132) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: 45% — 100th Percentile.

Left-handed hitters had a groundball rate of 77% (102/132) against Andre Pallante in 2023 — highest among qualified RPs in MLB; League Avg: 45% — 100th Percentile.

Opponents had a groundball rate of 77% (173/226) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: 45% — 100th Percentile.

Braves Starting Pitcher Stats & Trends

Opponents had a miss rate of 39% (635/1,644) against Spencer Strider in 2023 — best among qualified SPs in MLB; League Avg: 27% — 100th Percentile.

Right-handed hitters had a miss rate of 42% (332/783) against Spencer Strider in 2023 — best among qualified SPs in MLB; League Avg: 27% — 100th Percentile.

Opponents have a miss rate of 44% (142/324) against Spencer Strider on the first pitch of at-bats since the 2023 season — best in MLB among starting pitchers with at least 138 total IP; League Avg: 26% — 100th Percentile.

Opponents had a miss rate of 41% (396/971) against Spencer Strider in non-two strike counts in 2023 — best in MLB among starting pitchers with at least 64 total IP; League Avg: 25% — 100th Percentile.

Cardinals Keys to the Game vs. the Braves

The Cardinals are just 0-9 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .082.

The Cardinals are just 0-9 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .116.

The Cardinals are just 0-10 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .033.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Braves Keys to the Game vs. the Cardinals

The Braves are just 4-3 (.571) when leading entering the 7th inning this season — lowest in MLB; League Avg: .884.

The Braves are just 0-11 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .033.

The Braves are 3-10 (.231) when trailing entering the 8th inning this season — 3rd best in MLB; League Avg: .082.

The Braves are 202-144 (.584) since the 2023 season — 2nd best in MLB; League Avg: .500.

The Cardinals are batting .208 on pitches out of the zone this season — best in MLB; League Avg: .145.

The Cardinals have won just 40% of games in which they have scored in at least three different innings this season — 2nd lowest in MLB; League Avg: 73%.

The Cardinals are batting .292 at home this season — tied for best in MLB; League Avg: .250.

Cardinals hitters have an OBP of .359 (250 PA’s) against LHP this season — 3rd best in MLB; League Avg: .308.

Braves hitters had an OBP of .400 (732 PA’s) when facing the starting pitcher for the 3rd time in a game in 2023 — best in MLB; League Avg: .330.

Braves hitters slugged .521 against LHP in the 2023 season — best in MLB; League Avg: .419.

Braves hitters slugged .495 against RHP in the 2023 season — best in MLB; League Avg: .413.

Braves hitters are slugging .476 against LHP since the 2023 season — best in MLB; League Avg: .406.

Batters facing the Cardinals pitchers have struck out in the zone 46% of the time since last season — 2nd lowest in MLB; League Avg: 50%. since last season — 2nd lowest in MLB; League Avg: 50%.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — tied for 2nd lowest in MLB; League Avg: 26%.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Braves pitchers had a strikeout rate of 46% with two-strikes in the 2024 season — best in MLB; League Avg: 42%.

Batters facing the Braves pitchers have struck out in the zone 38% of the time over the last 14 days — lowest in MLB; League Avg: 52%. over the last 14 days — lowest in MLB; League Avg: 52%.

Batters facing the Braves pitchers have struck out in the zone 46% of the time since last season — lowest in MLB; League Avg: 50%. since last season — lowest in MLB; League Avg: 50%.

Braves pitchers walked 85 of 1,447 batters (6%) when facing the leadoff batter in the inning in the 2024 season — 2nd best in MLB; League Avg: 7%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.