Cardinals vs Nationals Prediction, Odds & Player Prop Bets Today – MLB, May 10

Washington Nationals' Luis Garcia hits an RBI single against the Seattle Mariners to score CJ Abrams during the third inning of a baseball game Monday, June 26, 2023, in Seattle.
(AP Photo/Lindsey Wasson)
  • The Cardinals are -118 favorites vs the Nationals
  • Cardinals vs Nationals Over / Under today: 9 Runs
  • Cardinals / Nationals TV Channel: FDMW | MASN

The St. Louis Cardinals (-118) visit Nationals Park to take on the Washington Nationals (-102) on Saturday, May 10, 2025. First pitch is scheduled for 4:05pm EDT in Washington, DC.

This season, the Cardinals are 20-19 against the spread (ATS), while the Nationals are 19-20 ATS.

Cardinals vs Nationals Starting Pitchers Today:

  • Cardinals starting pitcher: Andre Pallante 2-2, 4.80 ERA
  • Nationals starting pitcher: Trevor Williams 2-3, 5.86 ERA

Cardinals vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +145O 9 -102-118
Nationals +1.5 -175U 9 -118-102

Cardinals vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Saturday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Willson Contreras has hit the Home Runs Over in 3 of his last 9 games (+11.15 Units / 124% ROI)
  • Victor Scott II has hit the Singles Over in 11 of his last 15 games (+10.25 Units / 68% ROI)
  • Masyn Winn has hit the Hits Runs and RBIs Over in 15 of his last 20 away games (+10.05 Units / 43% ROI)
  • Masyn Winn has hit the Hits Over in 15 of his last 20 away games (+9.95 Units / 32% ROI)
  • Victor Scott II has hit the Total Bases Over in his last 9 games (+9.00 Units / 73% ROI)

And here are some favorite MLB player prop bets for Nationals players for Saturday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

  • Josh Bell has hit the Hits Under in 13 of his last 20 games (+10.30 Units / 45% ROI)
  • CJ Abrams has hit the Total Bases Over in 16 of his last 25 games (+9.15 Units / 30% ROI)
  • Josh Bell has hit the Runs Under in 16 of his last 20 games (+8.60 Units / 23% ROI)
  • Josh Bell has hit the Singles Under in 15 of his last 20 games (+8.20 Units / 30% ROI)
  • Dylan Crews has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+7.55 Units / 56% ROI)
  • The St. Louis Cardinals have covered the Run Line in their last 6 games (+7.30 Units / 97% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 11 of their last 16 games (+6.65 Units / 36% ROI)
  • The St. Louis Cardinals have hit the Game Total Over in 21 of their last 37 games (+5.50 Units / 14% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 16 of their last 25 games (+5.35 Units / 18% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 13 of their last 29 games (+3.50 Units / 11% ROI)
  • The Washington Nationals have hit the Game Total Over in 13 of their last 20 games at home (+6.40 Units / 29% ROI)
  • The Washington Nationals have hit the Moneyline in 10 of their last 18 games at home (+4.70 Units / 25% ROI)
  • The Washington Nationals have covered the Run Line in 18 of their last 32 games (+2.85 Units / 7% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 21-18 against the Run Line (-1.5 Units / -2.71% ROI).

  • 20-19 when betting on the Moneyline for +1 Units / 2.28% ROI
  • 22-15 when betting on the total runs Over for +5.4 Units / 12.6% ROI
  • 15-22 when betting on the total runs Under for -9.4 Units / -21.89% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 19-20 against the Run Line (-4 Units / -8.12% ROI).

  • 17-22 when betting on the Moneyline for -1.95 Units / -4.76% ROI
  • 21-17 when betting on the total runs Over for +2.6 Units / 6.1% ROI
  • 17-21 when betting on the total runs Under for -6.1 Units / -14.14% ROI

Nationals vs Cardinals Home Run Prop Bets Today

Over Under
Willson Contreras (STL) 0.5 +475 0.5 -650
Lars Nootbaar (STL) 0.5 +525 0.5 -750
Jordan Walker (STL) 0.5 +575 0.5 -900
Nolan Arenado (STL) 0.5 +650 0.5 -1000
Yohel Pozo (STL) 0.5 +650 0.5 -1100

Nationals vs Cardinals Total Hits Prop Bets Today

Over Under
Masyn Winn (STL) 0.5 -275 0.5 +195
Lars Nootbaar (STL) 0.5 -250 0.5 +185
Amed Rosario (WAS) 0.5 -250 0.5 +190
Nolan Arenado (STL) 0.5 -235 0.5 +175
CJ Abrams (WAS) 0.5 -235 0.5 +180

Nationals vs Cardinals RBI Prop Bets Today

Over Under
Nolan Arenado (STL) 0.5 +140 0.5 -190
Keibert Ruiz (WAS) 0.5 +160 0.5 -210
Brendan Donovan (STL) 0.5 +160 0.5 -210
Nathaniel Lowe (WAS) 0.5 +165 0.5 -220
Willson Contreras (STL) 0.5 +165 0.5 -220

Nationals vs Cardinals Strikeout Prop Bets Today

Over Under
Andre Pallante (STL) 3.5 -118 3.5 -110
Trevor Williams (WAS) 3.5 -118 3.5 -110

Opponents had a groundball rate of 77% (173/226) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: 45% — 100th Percentile.

Right-handed batters batted .357 (40-for-112) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: .231 — first Percentile.

Left-handed hitters had a groundball rate of 77% (102/132) against Andre Pallante in 2023 — highest among qualified RPs in MLB; League Avg: 45% — 100th Percentile.

Left-handed hitters have a groundball rate of 74% (266/361) against Andre Pallante since the 2023 season — highest in MLB among starting pitchers with at least 144 total IP; League Avg: 42% — 100th Percentile.

Nationals Starting Pitcher Stats & Trends

Trevor Williams has thrown his changeup for a strike just 30% (29/95) of the time this season — lowest in MLB among starting pitchers with at least 14 total IP; League Avg: 58% — first Percentile.

Opponents had a swing rate of just 34% (168/498) against Trevor Williams on sliders in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 49% — first Percentile.

Trevor Williams threw his off-speed pitches for a strike just 51% (619/1,221) of the time in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 62% — 0 Percentile.

Trevor Williams threw his breaking pitches for a strike just 51% (335/660) of the time in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 62% — 0 Percentile.

Cardinals Keys to the Game vs. the Nationals

The Cardinals are just 0-13 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .122.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

The Cardinals are just 16-143 (.101) when trailing entering the 7th inning since the 2023 season — 4th lowest in MLB; League Avg: .139.

The Cardinals are 82-5 (.943) when leading entering the 8th inning since last season — tied for 4th best in MLB; League Avg: .902.

Nationals Keys to the Game vs. the Cardinals

The Nationals were just 20-43 (.317) vs top 10 scoring offenses in the 2024 season They play the Dodgers (second best runs scored) today.

The Nationals are just 48-162 (.229) when scoring 4 or fewer runs since the 2023 season — 5th lowest in MLB; League Avg: .273.

The Nationals are just 87-113 (.433) since last season — 5th lowest in MLB; League Avg: .500.

The Nationals are just 62-95 (.392) after a win since the 2023 season — 3rd lowest in MLB; League Avg: .506.

The Cardinals are batting .353 on changeups this season — best in MLB; League Avg: .235.

The Cardinals are batting .208 on pitches out of the zone this season — best in MLB; League Avg: .151.

The Cardinals are batting .288 at home this season — best in MLB; League Avg: .250.

The Cardinals are batting .262 this season — tied for best in MLB; League Avg: .243.

Nationals hitters put 41% of their swings in play against LHP in 2023 — highest in MLB; League Avg: 37%.

The Nationals batted just .226 when facing the starting pitcher for the 3rd time in a game in the 2024 season — 2nd lowest in MLB; League Avg: .263.

Nationals hitters struck out just 340 times in 1,868 PA’s (18%) against LHP in 2023 — tied for best in MLB; League Avg: 23%.

Nationals hitters struck out just 809 times in 4,217 PA’s (19%) against RHP in 2023 — 2nd best in MLB; League Avg: 23%.

Cardinals pitchers had a strikeout rate of just 19% in 2023 — 2nd lowest in MLB; League Avg: 23%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Batters facing the Cardinals pitchers have struck out in the zone 46% of the time since last season — 2nd lowest in MLB; League Avg: 50%. since last season — 2nd lowest in MLB; League Avg: 50%.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

The Nationals have allowed 2.36 runs per game (92/39) in late innings this season — highest in MLB; League Avg: 1.35.

Nationals pitchers have allowed an OBP of .341 (3,209 PA’s) when facing the leadoff batter in the inning since the 2023 season — 2nd highest in MLB; League Avg: .311.

Nationals pitchers have a strikeout rate of just 39% with two-strikes since the 2023 season — 2nd lowest in MLB; League Avg: 42%.

Nationals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.