Cardinals vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Apr 3

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Padres are -150 favorites vs the Cardinals
  • Cardinals vs Padres Over / Under today: 8.5 Runs
  • Cardinals / Padres TV Channel: BSMW | MLBN | PDTV

The St. Louis Cardinals (+125) visit Petco Park to take on the San Diego Padres (-150) on Wednesday, April 3, 2024. First pitch is scheduled for 4:10pm EDT in San Diego, CA.

This season, the Cardinals are 3-3 against the spread (ATS), while the Padres are 3-5 ATS.

Cardinals vs Padres Starting Pitchers Today:

  • Cardinals starting pitcher: Zack Thompson 0-1, 8.44 ERA
  • Padres starting pitcher: Joe Musgrove 0-1, 9.73 ERA

Cardinals vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -160O 8.5 -120+125
Padres -1.5 +135U 8.5 +100-150

Cardinals vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 55.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Paul Goldschmidt has hit the Total Bases Under in 10 of his last 11 away games (+9.85 Units / 56% ROI)
  • Richie Palacios has hit the Singles Under in 15 of his last 19 games (+9.75 Units / 39% ROI)
  • Paul Goldschmidt has hit the Hits Under in 8 of his last 12 away games (+8.10 Units / 59% ROI)
  • Nolan Gorman has hit the Singles Over in 5 of his last 6 away games (+7.45 Units / 124% ROI)
  • Lance Lynn has hit the Strikeouts Under in 8 of his last 9 away games (+6.90 Units / 50% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Jake Cronenworth has hit the Total Bases Over in 28 of his last 39 games (+18.10 Units / 33% ROI)
  • Blake Snell has hit the Earned Runs Under in 21 of his last 26 games (+15.80 Units / 46% ROI)
  • Xander Bogaerts has hit the Hits Runs and RBIs Over in 25 of his last 34 games (+14.20 Units / 32% ROI)
  • Xander Bogaerts has hit the Total Bases Over in 22 of his last 34 games (+12.65 Units / 28% ROI)
  • Blake Snell has hit the Pitching Outs Over in 20 of his last 27 games (+12.35 Units / 38% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 22 of their last 45 away games (+9.80 Units / 20% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 away games (+9.13 Units / 18% ROI)
  • The St. Louis Cardinals have hit the Team Total Under in 46 of their last 79 away games (+8.70 Units / 10% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 9 of their last 11 away games (+6.85 Units / 57% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 8 of their last 15 away games (+5.85 Units / 38% ROI)
  • The San Diego Padres have hit the Game Total Under in 84 of their last 155 games (+17.70 Units / 10% ROI)
  • The San Diego Padres have covered the Run Line in 31 of their last 55 games at home (+12.50 Units / 21% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 4-2 against the Run Line (+2 Units / 25.32% ROI).

  • 3-3 when betting on the Moneyline for +1.45 Units / 24.17% ROI
  • 2-2 when betting on the total runs Over for +0 Units / 0% ROI
  • 2-2 when betting on the total runs Under for -0.15 Units / -2.19% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 3-5 against the Run Line (-1.03 Units / -12.58% ROI).

  • 3-5 when betting on the Moneyline for -2.81 Units / -27.55% ROI
  • 5-2 when betting on the total runs Over for +2.87 Units / 32.14% ROI
  • 2-5 when betting on the total runs Under for -3.5 Units / -39.68% ROI

Padres vs Cardinals Home Run Prop Bets Today

Over Under
Gorman 0.5 +450 0.5 -650
Arenado 0.5 +650 0.5 -1100
Donovan 0.5 +825 0.5 -1400
Scott II 0.5 +1050 0.5 -2500
Winn 0.5 +1450 0.5 -5000

Padres vs Cardinals Strikeout Prop Bets Today

Over Under
Musgrove 6.5 +105 6.5 -140
Thompson 4.5 +115 4.5 -150

Zack Thompson has allowed a slugging percentage of .762 (16 Total Bases / 21 ABs) this season — 5th highest among qualified SPs in MLB; League Avg: .379 — fourth Percentile.

Zack Thompson has allowed an OPS of 1.110 (23 PA’s) this season — 6th highest among qualified SPs in MLB; League Avg: .672 — fifth Percentile.

Zack Thompson has allowed a slugging percentage of .762 (16 Total Bases / 21 ABs) this season — 4th highest among in MLB; League Avg: .396 — seventh Percentile.

Zack Thompson has allowed a slugging percentage of .941 (16 Total Bases / 17 ABs) on pitches in the strike zone this season — 3rd highest among qualified SPs in MLB; League Avg: .439 — fourth Percentile.

Padres Starting Pitcher Stats & Trends

Joe Musgrove has struck out just 5% (1/20) of right-handed batters he faced this season — lowest among qualified SPs in MLB; League Avg: 23% — second Percentile.

Opponents are hitting .405 (15-for-37) against Joe Musgrove this season — 5th highest among qualified SPs in MLB; League Avg: .232 — fourth Percentile.

Joe Musgrove has a strikeout rate of just 12% (5 SO in 43 PAs) this season — 13th lowest among qualified SPs in MLB; League Avg: 24% — 11th Percentile.

Joe Musgrove has allowed an OBP of .465 (43 PA’s) this season — 3rd highest among in MLB; League Avg: .313 — sixth Percentile.

Cardinals Keys to the Game vs. the Padres

The Cardinals are 27-10 (.730) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .497.

The Cardinals were just 4-70 (.054) when trailing entering the 7th inning in 2023 — lowest in MLB; League Avg: .141.

The Cardinals were just 4-77 (.049) when trailing entering the 8th inning in 2023 — 5th lowest in MLB; League Avg: .101.

The Cardinals were just 19-28 (.404) after a home loss in 2023 — 4th lowest in MLB; League Avg: .508.

Padres Keys to the Game vs. the Cardinals

The Padres were just 2-13 (.133) after a win as underdogs in 2023 — lowest in MLB; League Avg: .430.

The Padres were just 3-63 (.045) when trailing entering the 8th inning in 2023 — 4th lowest in MLB; League Avg: .101.

The Padres were just 1-66 (.015) when trailing entering the 9th inning in 2023 — 4th lowest in MLB; League Avg: .051.

The Padres are just 15-29 (.341) after a win as underdogs since the 2022 season — 3rd lowest in MLB; League Avg: .415.

The Cardinals are batting just .100 against LHP this season — lowest in MLB; League Avg: .257.

Cardinals hitters are slugging just .100 against LHP this season — lowest in MLB; League Avg: .404.

Cardinals hitters have drawn 5 walks in 28 PA’s (18%) against LHP this season — best in MLB; League Avg: 10%.

Cardinals hitters have an OPS of just .396 (28 PA’s) against LHP this season — 2nd lowest in MLB; League Avg: .742.

The Padres are batting just .107 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB; League Avg: .257.

Padres hitters have a swing rate of just 45% against RHP since the 2022 season — lowest in MLB; League Avg: 48%.

Padres hitters have a swing rate of just 45% against RHP since last season — lowest in MLB; League Avg: 47%.

Padres hitters drew 494 walks in 4,481 PA’s (11%) against RHP in the 2023 season — best in MLB; League Avg: 9%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 19% in the 2023 season — 2nd lowest in MLB; League Avg: 23%.

Cardinals pitchers have a strikeout rate of just 38% with two-strikes since the 2022 season — tied for 2nd lowest in MLB; League Avg: 42%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in the 2023 season — tied for 2nd lowest in MLB; League Avg: 43%.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

Opponents had a groundball rate of 45% against Padres pitchers in the 2023 season — 3rd highest in MLB; League Avg: 43%.

Padres pitchers have walked 36 of 334 batters (11%) this season — 5th highest in MLB; League Avg: 9%.

Padres pitchers have walked 10 of 72 batters (14%) when facing the leadoff batter in the inning this season — 4th highest in MLB; League Avg: 10%.

Padres vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL
  • Dylan Carlson (St. Louis Cardinals): Shoulder, 10-Day IL
  • Keynan Middleton (St. Louis Cardinals): Forearm, 15-Day IL
  • Lars Nootbaar (St. Louis Cardinals): Ribs, 10-Day IL
  • Drew Rom (St. Louis Cardinals): Biceps, 15-Day IL
  • Sonny Gray (St. Louis Cardinals): Hamstring, 15-Day IL
  • Riley O’Brien (St. Louis Cardinals): Forearm, 15-Day IL
  • Tommy Edman (St. Louis Cardinals): Wrist, 10-Day IL
  • Packy Naughton (St. Louis Cardinals): Elbow, Out

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.