Cardinals vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Apr 29

Cincinnati Reds' Elly De La Cruz watches his hit during the first inning of a spring training baseball game against the Cleveland Guardians, Saturday, Feb. 24, 2024, in Goodyear, Ariz.
(AP Photo/Carolyn Kaster)
  • The Reds are -140 favorites vs the Cardinals
  • Cardinals vs Reds Over / Under today: 9.5 Runs
  • Cardinals / Reds TV Channel: FDOH | FDMW

The St. Louis Cardinals (+115) visit Great American Ball Park to take on the Cincinnati Reds (-140) on Tuesday, April 29, 2025. First pitch is scheduled for 6:40pm EDT in Cincinnati, OH, OH.

This season, the Cardinals are 12-17 against the spread (ATS), while the Reds are 17-12 ATS.

Cardinals vs Reds Starting Pitchers Today:

  • Cardinals starting pitcher: Miles Mikolas 0-2, 5.71 ERA
  • Reds starting pitcher: Brady Singer 4-0, 3.63 ERA

Cardinals vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -190O 9.5 -110+115
Reds -1.5 +155U 9.5 -110-140

Cardinals vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Tuesday‘s MLB game with 54.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Brendan Donovan has hit the Hits Over in 17 of his last 20 games (+12.15 Units / 29% ROI)
  • Jordan Walker has hit the Total Bases Under in 9 of his last 10 away games (+9.35 Units / 75% ROI)
  • Jordan Walker has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+8.95 Units / 34% ROI)
  • Brendan Donovan has hit the Singles Over in 18 of his last 25 away games (+8.35 Units / 25% ROI)
  • Brendan Donovan has hit the Home Runs Over in 1 of his last 5 away games (+8.00 Units / 160% ROI)

And here are some favorite MLB player prop bets for Reds players for Tuesday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • Noelvi Marte has hit the Home Runs Over in 3 of his last 8 games (+21.70 Units / 271% ROI)
  • Jose Trevino has hit the Singles Under in 21 of his last 25 games at home (+15.05 Units / 42% ROI)
  • Jose Trevino has hit the Hits Under in 18 of his last 25 games at home (+14.60 Units / 57% ROI)
  • Jose Trevino has hit the Total Bases Under in 18 of his last 25 games at home (+14.15 Units / 53% ROI)
  • Jose Trevino has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+12.90 Units / 38% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 11 of their last 18 games (+4.50 Units / 23% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 13 away games (+4.05 Units / 25% ROI)
  • The St. Louis Cardinals have hit the Team Total Under in 4 of their last 5 games (+3.20 Units / 59% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 8 of their last 19 games (+1.90 Units / 9% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 9 of their last 15 games (+1.85 Units / 10% ROI)
  • The Cincinnati Reds have hit the Moneyline in 13 of their last 19 games (+7.95 Units / 34% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 12 of their last 18 games (+7.65 Units / 31% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 13 of their last 19 games (+6.80 Units / 30% ROI)
  • The Cincinnati Reds have covered the Run Line in 17 of their last 26 games (+6.55 Units / 18% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 11 of their last 17 games (+4.35 Units / 21% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 13-16 against the Run Line (-8.15 Units / -19.31% ROI).

  • 12-17 when betting on the Moneyline for -5.55 Units / -17.18% ROI
  • 15-12 when betting on the total runs Over for +1.65 Units / 5.15% ROI
  • 12-15 when betting on the total runs Under for -4.55 Units / -14.33% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 17-12 against the Run Line (+2.2 Units / 5.29% ROI).

  • 16-13 when betting on the Moneyline for +3.55 Units / 10.33% ROI
  • 13-15 when betting on the total runs Over for -3.5 Units / -10.95% ROI
  • 15-13 when betting on the total runs Under for +0.75 Units / 2.35% ROI

Reds vs Cardinals Home Run Prop Bets Today

Over Under
Nolan Gorman (STL) 0.5 +325 0.5 -450
Austin Hays (CIN) 0.5 +325 0.5 -450
Elly De La Cruz (CIN) 0.5 +375 0.5 -525
Matt McLain (CIN) 0.5 +400 0.5 -550
Willson Contreras (STL) 0.5 +425 0.5 -600

Reds vs Cardinals Total Hits Prop Bets Today

Over Under
Noelvi Marte (CIN) 0.5 -275 0.5 +195
Brendan Donovan (STL) 0.5 -275 0.5 +200
Gavin Lux (CIN) 0.5 -250 0.5 +190
TJ Friedl (CIN) 0.5 -235 0.5 +180
Willson Contreras (STL) 0.5 -235 0.5 +175

Reds vs Cardinals RBI Prop Bets Today

Over Under
Austin Hays (CIN) 0.5 -105 0.5 -125
Elly De La Cruz (CIN) 0.5 +140 0.5 -185
Nolan Arenado (STL) 0.5 +150 0.5 -200
Spencer Steer (CIN) 0.5 +150 0.5 -200
Noelvi Marte (CIN) 0.5 +155 0.5 -210

Reds vs Cardinals Strikeout Prop Bets Today

Over Under
Miles Mikolas (STL) 3.5 -118 3.5 -110
Brady Singer (CIN) 5.5 +100 5.5 -130

Opponents had a two strike miss rate of just 14% (74/529) against Miles Mikolas in the 2024 season — lowest among qualified SPs in MLB; League Avg: 25% — first Percentile.

Opponents are hitting .228 (89-for-390) against Miles Mikolas with two-strikes since last season — 2nd highest among qualified SPs in MLB; League Avg: .162 — third Percentile.

Opponents had a miss rate of just 16% (221/1,347) against Miles Mikolas in the 2024 season — lowest among qualified SPs in MLB; League Avg: 26% — first Percentile.

Opponents are hitting .295 (118-for-400) against Miles Mikolas’ non-fastballs since last season — highest among qualified SPs in MLB; League Avg: .217 — second Percentile.

Reds Starting Pitcher Stats & Trends

Brady Singer has thrown inside pitches 58% of the time (171/296) vs left-handed batters this season — highest among among NL Starters; League Avg: 32% — 100th Percentile.

Brady Singer has thrown inside pitches 58% of the time (171/296) vs left-handed batters this season — highest among qualified SPs in MLB; League Avg: 32% — 100th Percentile.

Brady Singer has thrown inside pitches 50% of the time (70/140) with two-strikes this season — highest among among NL Starters; League Avg: 30% — 100th Percentile.

Opponents batted .372 (32-for-86) against Brady Singer’s elevated fastballs in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: .229 — 0 Percentile.

Cardinals Keys to the Game vs. the Reds

The Cardinals are just 0-13 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .041.

The Cardinals are just 10-152 (.062) when trailing entering the 8th inning since the 2023 season — tied for 3rd lowest in MLB; League Avg: .098.

The Cardinals are just 0-11 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .083.

The Cardinals are just 12-17 (.414) this season — 5th lowest in MLB; League Avg: .500.

Reds Keys to the Game vs. the Cardinals

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds were just 8-18 (.308) when tied entering the 7th inning in the 2024 season — tied for 2nd lowest in MLB; League Avg: .498.

The Reds are just 14-27 (.341) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 10-18 (.357) when tied entering the 7th inning since last season — 4th lowest in MLB; League Avg: .499.

The Cardinals are batting .216 on pitches out of the zone this season — best in MLB; League Avg: .149.

The Cardinals are batting .379 on changeups this season — best in MLB; League Avg: .237.

Cardinals hitters have a groundball batting average of .295 this season — best in MLB; League Avg: .249.

The Cardinals have a winning percentage of just 14% on the road since the 2023 season — 2nd lowest in MLB; League Avg: 40%.

Reds hitters are slugging just .156 on pitches out of the zone since last season — lowest in MLB; League Avg: .204.

Reds hitters have chased 24% of pitches out of the zone against LHP this season — lowest in MLB; League Avg: 29%.

The Reds are batting just .118 on pitches out of the zone since last season — lowest in MLB; League Avg: .150.

The Reds are batting just .224 against LHP since last season — 3rd lowest in MLB; League Avg: .244.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Cardinals pitchers have a strikeout rate of just 36% with two-strikes this season — lowest in MLB; League Avg: 42%.

Cardinals pitchers had a strikeout rate of just 19% in 2023 — 2nd lowest in MLB; League Avg: 23%.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Reds pitchers walked 613 of 6,310 batters (10%) in 2023 — tied for 4th highest in MLB; League Avg: 9%.

Opponents have a groundball rate of just 36% against Reds pitchers this season — lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.