Chicago Cubs vs St. Louis Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Jun 23

  • The Chicago Cubs are -110 favorites vs the St. Louis Cardinals
  • Chicago Cubs vs St. Louis Cardinals Over / Under today: 9 Runs
  • Chicago Cubs / St. Louis Cardinals TV Channel: MARQ | FDMW

The Chicago Cubs (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Monday, June 23, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO, MO.

This season, the Chicago Cubs are 46-31 against the spread (ATS), while the St. Louis Cardinals are 43-35 ATS.

Chicago Cubs vs St. Louis Cardinals Starting Pitchers Today:

  • Chicago Cubs starting pitcher: , ERA
  • St. Louis Cardinals starting pitcher: , ERA

Chicago Cubs vs. St. Louis Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Chicago Cubs-1.5 +150O 8.5 +100-110
St. Louis Cardinals +1.5 -185U 8.5 -120-110

Chicago Cubs vs St. Louis Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the will win Monday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Chicago Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Chicago Cubs Player Prop Bets Today:

  • Pete Crow-Armstrong has hit the Home Runs Over in 4 of his last 9 games (+13.80 Units / 153% ROI)
  • Dansby Swanson has hit the Runs Under in 19 of his last 25 games (+9.85 Units / 23% ROI)
  • Pete Crow-Armstrong has hit the Total Bases Over in 16 of his last 25 away games (+8.60 Units / 28% ROI)
  • Pete Crow-Armstrong has hit the Singles Under in 18 of his last 25 away games (+8.50 Units / 25% ROI)
  • Ian Happ has hit the Hits Over in 19 of his last 25 away games (+8.25 Units / 17% ROI)

And here are some favorite MLB player prop bets for St. Louis Cardinals players for Monday‘s game, looking at profitable historical betting trends:

Best St. Louis Cardinals Player Prop Best Bets Today:

  • Alec Burleson has hit the Total Bases Over in 20 of his last 25 games (+16.85 Units / 52% ROI)
  • Willson Contreras has hit the RBIs Over in 14 of his last 20 games (+15.15 Units / 76% ROI)
  • Nolan Arenado has hit the Home Runs Over in 2 of his last 4 games at home (+12.60 Units / 315% ROI)
  • Masyn Winn has hit the Runs Over in 16 of his last 25 games at home (+10.85 Units / 42% ROI)
  • Masyn Winn has hit the Hits Runs and RBIs Over in 17 of his last 25 games at home (+8.35 Units / 27% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 39 of their last 75 games (+12.70 Units / 12% ROI)
  • The Chicago Cubs have hit the Moneyline in 44 of their last 71 games (+11.25 Units / 10% ROI)
  • The Chicago Cubs have hit the Game Total Under in 15 of their last 24 games (+7.25 Units / 27% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 41 of their last 73 games (+5.70 Units / 6% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in their last 5 games (+5.20 Units / 92% ROI)
  • The St. Louis Cardinals have covered the Run Line in 28 of their last 45 games (+12.15 Units / 21% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 33 of their last 55 games (+10.85 Units / 17% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 25 of their last 39 games at home (+10.77 Units / 24% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 29 games (+7.95 Units / 22% ROI)
  • The St. Louis Cardinals have hit the Game Total Over in 15 of their last 26 games at home (+5.25 Units / 18% ROI)

Chicago Cubs Against the Spread (ATS) Record

Against the spread this season, the Chicago Cubs are 38-39 against the Run Line (-0.48 Units / -0.52% ROI).

  • 46-31 when betting on the Moneyline for +9.15 Units / 8.05% ROI
  • 39-33 when betting on the total runs Over for +3.25 Units / 3.88% ROI
  • 33-39 when betting on the total runs Under for -10.15 Units / -11.86% ROI

St. Louis Cardinals Against the Spread (ATS) Record

Against the spread this season, the St. Louis Cardinals are 43-35 against the Run Line (+3.35 Units / 3.18% ROI).

  • 42-36 when betting on the Moneyline for +5.2 Units / 5.73% ROI
  • 41-33 when betting on the total runs Over for +4.8 Units / 5.61% ROI
  • 33-41 when betting on the total runs Under for -12.25 Units / -14.24% ROI

St. Louis Cardinals vs Chicago Cubs Home Run Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +350 0.5 -450
Nolan Gorman (STL) 0.5 +425 0.5 -625
Alec Burleson (STL) 0.5 +425 0.5 -600
Willson Contreras (STL) 0.5 +450 0.5 -625
Ian Happ (CHC) 0.5 +475 0.5 -650

St. Louis Cardinals vs Chicago Cubs Total Hits Prop Bets Today

Over Under
Ian Happ (CHC) 0.5 -275 0.5 +200
Kyle Tucker (CHI) 0.5 -275 0.5 +200
Masyn Winn (STL) 0.5 -250 0.5 +190
Carson Kelly (CHC) 0.5 -235 0.5 +175
Willson Contreras (STL) 0.5 -235 0.5 +180

St. Louis Cardinals vs Chicago Cubs RBI Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +115 0.5 -150
Dansby Swanson (CHC) 0.5 +130 0.5 -175
Willson Contreras (STL) 0.5 +155 0.5 -210
Alec Burleson (STL) 0.5 +155 0.5 -200
Ian Happ (CHC) 0.5 +160 0.5 -220

St. Louis Cardinals vs Chicago Cubs Strikeout Prop Bets Today

Over Under
Ben Brown (CHC) 4.5 -145 4.5 +110
Matthew Liberatore (STL) 3.5 -135 3.5 +100

starting pitcher – away

St. Louis Cardinals Starting Pitcher Stats & Trends

starting pitcher – home

Chicago Cubs Keys to the Game vs. the St. Louis Cardinals

keys to the game – away

St. Louis Cardinals Keys to the Game vs. the Chicago Cubs

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.