Cubs vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Apr 14

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Padres are -170 favorites vs the Cubs
  • Cubs vs Padres Over / Under today: 7.5 Runs
  • Cubs / Padres TV Channel: MARQ | PDTV | MLBN

The Chicago Cubs (+135) visit Petco Park to take on the San Diego Padres (-165) on Monday, April 14, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA.

This season, the Cubs are 11-7 against the spread (ATS), while the Padres are 11-5 ATS.

Cubs vs Padres Starting Pitchers Today:

  • Cubs starting pitcher: Jameson Taillon 1-1, 6.07 ERA
  • Padres starting pitcher: Dylan Cease 1-1, 7.98 ERA

Cubs vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -165O 7.5 -115+135
Padres -1.5 +140U 7.5 -105-165

Cubs vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Monday‘s MLB game with 59.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Seiya Suzuki has hit the Home Runs Over in 3 of his last 6 away games (+14.30 Units / 238% ROI)
  • Pete Crow-Armstrong has hit the Runs Over in 15 of his last 25 away games (+12.40 Units / 49% ROI)
  • Pete Crow-Armstrong has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+10.50 Units / 40% ROI)
  • Nico Hoerner has hit the Singles Over in 19 of his last 25 away games (+10.35 Units / 28% ROI)
  • Nico Hoerner has hit the Hits Over in 18 of his last 25 away games (+9.45 Units / 19% ROI)

And here are some favorite MLB player prop bets for Padres players for Monday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Gavin Sheets has hit the Home Runs Over in 3 of his last 10 games at home (+14.30 Units / 143% ROI)
  • Fernando Tatis Jr. has hit the Total Bases Over in 16 of his last 20 games at home (+13.75 Units / 63% ROI)
  • Jose Iglesias has hit the Hits Over in 16 of his last 20 games at home (+11.85 Units / 32% ROI)
  • Jason Heyward has hit the Singles Under in his last 10 games at home (+10.00 Units / 49% ROI)
  • Fernando Tatis Jr. has hit the Hits Runs and RBIs Over in 15 of his last 20 games at home (+9.50 Units / 39% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 13 of their last 14 games (+12.40 Units / 75% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+9.65 Units / 46% ROI)
  • The Chicago Cubs have covered the Run Line in 49 of their last 83 away games (+7.40 Units / 6% ROI)
  • The Chicago Cubs have hit the Moneyline in 43 of their last 83 away games (+7.05 Units / 8% ROI)
  • The Chicago Cubs have hit the Team Total Over in 10 of their last 13 games (+7.00 Units / 47% ROI)
  • The San Diego Padres have hit the Moneyline in 102 of their last 168 games (+22.10 Units / 10% ROI)
  • The San Diego Padres have covered the Run Line in 88 of their last 168 games (+7.90 Units / 4% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 10 of their last 14 games (+5.30 Units / 32% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 9 of their last 13 games (+4.70 Units / 24% ROI)
  • The San Diego Padres have hit the Team Total Over in 10 of their last 16 games (+4.10 Units / 23% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 11-7 against the Run Line (+5.2 Units / 22.61% ROI).

  • 11-7 when betting on the Moneyline for +4.25 Units / 19.54% ROI
  • 12-5 when betting on the total runs Over for +6.7 Units / 34.36% ROI
  • 5-12 when betting on the total runs Under for -8.3 Units / -41.29% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 11-5 against the Run Line (+6 Units / 29.2% ROI).

  • 13-3 when betting on the Moneyline for +10.3 Units / 45.58% ROI
  • 7-8 when betting on the total runs Over for -1.75 Units / -9.94% ROI
  • 8-7 when betting on the total runs Under for +0.15 Units / 0.85% ROI

Padres vs Cubs Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +280 0.5 -350
Manny Machado (SD) 0.5 +425 0.5 -600
Kyle Tucker (CHC) 0.5 +475 0.5 -650
Michael Busch (CHC) 0.5 +550 0.5 -800
Seiya Suzuki (CHC) 0.5 +575 0.5 -900

Padres vs Cubs Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -235 0.5 +180
Jose Iglesias (SD) 0.5 -235 0.5 +175
Nico Hoerner (CHC) 0.5 -210 0.5 +155
Gavin Sheets (SD) 0.5 -185 0.5 +135
Kyle Tucker (CHC) 0.5 -165 0.5 +125

Padres vs Cubs RBI Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +145 0.5 -190
Manny Machado (SD) 0.5 +155 0.5 -210
Seiya Suzuki (CHC) 0.5 +210 0.5 -285
Michael Busch (CHC) 0.5 +210 0.5 -285
Gavin Sheets (SD) 0.5 +210 0.5 -285

Padres vs Cubs Strikeout Prop Bets Today

Over Under
Jameson Taillon (CHC) 3.5 -155 3.5 +120
Dylan Cease (SD) 6.5 -110 6.5 -118

Jameson Taillon has allowed an OBP of just .228 (149 PA’s) with runners in scoring position since last season — best among qualified SPs in MLB; League Avg: .305 — 100th Percentile.

Jameson Taillon has allowed a slugging percentage of .893 (25 Total Bases / 28 ABs) against right-handed batters this season — highest among qualified SPs in MLB; League Avg: .356 — first Percentile.

Right-handed batters are hitting .393 (11-for-28) against Jameson Taillon this season — highest among qualified SPs in MLB; League Avg: .216 — first Percentile.

Jameson Taillon has allowed a slugging percentage of .760 (19 Total Bases / 25 ABs) when going through the lineup the second time in a game this season — highest among qualified SPs in MLB; League Avg: .356 — first Percentile.

Padres Starting Pitcher Stats & Trends

Dylan Cease allowed an OBP of just .269 (757 PAs) last season — tied for seventh best among qualified SPs– 89th Percentile. He allowed an OBP of .332 (784 PAs) in the 2023 season — third worst among qualified SPs– sixth Percentile.

Dylan Cease has thrown breaking pitches 55% of the time (1,886/3,451) since last season — highest among among NL Starters; League Avg: 31% — 100th Percentile.

Dylan Cease has walked 67 of 611 batters (11%) when going through the lineup the second time in a game since the 2023 season — highest among qualified SPs in MLB; League Avg: 6% — third Percentile.

Dylan Cease has thrown breaking pitches 60% of the time (1,002/1,682) against right-handed batters since last season — highest among among NL Starters; League Avg: 32% — 100th Percentile.

Cubs Keys to the Game vs. the Padres

The Cubs are 7-3 (.700) on the road this season — 2nd best in MLB; League Avg: .389.

The Cubs are 35-11 (.761) when they’ve scored in the first inning since last season — 2nd best in MLB; League Avg: .640.

The Cubs are 50-35 (.588) after a loss since last season — 4th best in MLB; League Avg: .505.

The Cubs are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .029.

Padres Keys to the Game vs. the Cubs

The Padres are 13-3 (.812) this season — best in MLB; League Avg: .500.

The Padres are 137-21 (.867) when scoring 5 or more runs since the 2023 season — 2nd best in MLB; League Avg: .793.

The Padres are 84-5 (.944) when leading entering the 8th inning since last season — 5th best in MLB; League Avg: .901.

The Padres are 15-58 (.205) when trailing entering the 7th inning since last season — 5th best in MLB; League Avg: .142.

Cubs hitters have an OPS of .875 (424 PA’s) on the road this season — best in MLB; League Avg: .661.

Cubs hitters are slugging .521 on the road this season — best in MLB; League Avg: .362.

The Cubs have scored 53 runs with two outs this season — most in MLB.

The Cubs have scored 116 runs this season — most in MLB.

The Padres are batting .313 with two outs this season — best in MLB; League Avg: .228.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters have just 313 strikeouts in 1,825 PA’s (17%) against LHP since last season — best in MLB; League Avg: 23%.

The Padres batted .201 with two-strikes in the 2024 season — best in MLB; League Avg: .168.

Cubs pitchers have walked 143 of 1,596 batters (9%) when facing the leadoff batter in the inning since last season — tied for 2nd highest in MLB; League Avg: 8%.

Cubs pitchers walked 127 of 1,437 batters (9%) when facing the leadoff batter in the inning in the 2024 season — 3rd highest in MLB; League Avg: 7%.

Cubs pitchers had an ERA of 3.08 (733.0 IP) at home in the 2024 season — 2nd best in MLB; League Avg: 3.98.

Cubs pitchers have walked 16 of 159 batters (10%) when facing the leadoff batter in the inning this season — tied for 5th highest in MLB; League Avg: 9%.

The Padres pitchers have allowed an average Exit Velocity of just 88.2 MPH since the 2023 season (8,238 balls in play) — best in MLB; League Avg: 88.9

Opponents have a miss rate of 28% against Padres pitchers this season — 3rd best in MLB; League Avg: 26%.

Padres pitchers have an ERA of 1.10 (90.0 IP) at home this season — best in MLB; League Avg: 3.44.

Opponents had a miss rate of 27% against Padres pitchers in the 2024 season — tied for 4th best in MLB; League Avg: 25%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.