- The Diamondbacks are -130 favorites vs the Cardinals
- Diamondbacks vs Cardinals Over / Under today: 8.5 Runs
- Diamondbacks / Cardinals TV Channel: ATV
The Arizona Diamondbacks (-130) visit Busch Stadium to take on the St. Louis Cardinals (+105) on Friday, May 23, 2025. First pitch is scheduled for 8:15pm EDT in St. Louis, MO, MO.
This season, the Diamondbacks are 26-24 against the spread (ATS), while the Cardinals are 30-20 ATS.
Diamondbacks vs Cardinals Starting Pitchers Today:
- Diamondbacks starting pitcher: Zac Gallen 3-5, 5.15 ERA
- Cardinals starting pitcher: Miles Mikolas 3-2, 3.75 ERA
Diamondbacks vs. Cardinals Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Diamondbacks | -1.5 +135 | O 8.5 -102 | -130 |
| Cardinals | +1.5 -165 | U 8.5 -118 | +105 |
Diamondbacks vs Cardinals Prediction for Today’s Game
Based on recent trends the model predicts the Diamondbacks will win Friday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Friday‘s game, looking at profitable historical betting trends:
Best Diamondbacks Player Prop Bets Today:
- Gabriel Moreno has hit the Home Runs Over in 3 of his last 10 games (+20.00 Units / 200% ROI)
- Geraldo Perdomo has hit the Total Bases Over in 17 of his last 20 games (+13.40 Units / 45% ROI)
- Geraldo Perdomo has hit the Hits Over in 17 of his last 20 games (+13.30 Units / 43% ROI)
- Geraldo Perdomo has hit the Singles Over in 13 of his last 20 games (+7.65 Units / 35% ROI)
- Pavin Smith has hit the Walks Under in 8 of his last 9 games (+6.90 Units / 51% ROI)
And here are some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Best Bets Today:
- Alec Burleson has hit the Home Runs Over in 4 of his last 9 games (+29.00 Units / 322% ROI)
- Alec Burleson has hit the Total Bases Over in 17 of his last 25 games (+10.25 Units / 29% ROI)
- Victor Scott II has hit the Hits Over in his last 9 games at home (+9.00 Units / 73% ROI)
- Alec Burleson has hit the Hits Runs and RBIs Over in 9 of his last 10 games (+8.55 Units / 77% ROI)
- Ivan Herrera has hit the Runs Over in 7 of his last 10 games (+8.05 Units / 81% ROI)
Diamondbacks Best Bets Today:
- The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 22 of their last 34 games (+10.05 Units / 25% ROI)
- The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 20 of their last 34 games (+9.40 Units / 20% ROI)
- The Arizona Diamondbacks have hit the Game Total Under in 15 of their last 21 games (+8.45 Units / 37% ROI)
- The Arizona Diamondbacks have hit the Team Total Over in 28 of their last 50 games (+3.35 Units / 6% ROI)
- The Arizona Diamondbacks have hit the Moneyline in 10 of their last 18 away games (+3.05 Units / 15% ROI)
Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the Run Line in 15 of their last 17 games (+14.20 Units / 60% ROI)
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 24 of their last 36 games (+10.45 Units / 24% ROI)
- The St. Louis Cardinals have hit the Moneyline in 18 of their last 27 games (+10.40 Units / 34% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 18 of their last 40 games (+7.35 Units / 16% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 11 of their last 16 games at home (+5.93 Units / 33% ROI)
Diamondbacks Against the Spread (ATS) Record
Against the spread this season, the Diamondbacks are 23-27 against the Run Line (-8.81 Units / -13.49% ROI).
- 26-24 when betting on the Moneyline for -2.95 Units / -4.39% ROI
- 22-25 when betting on the total runs Over for -5.65 Units / -10.26% ROI
- 25-22 when betting on the total runs Under for +0.6 Units / 1.09% ROI
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 30-20 against the Run Line (+5.4 Units / 7.56% ROI).
- 27-23 when betting on the Moneyline for +4.75 Units / 8.5% ROI
- 26-22 when betting on the total runs Over for +1.85 Units / 3.38% ROI
- 22-26 when betting on the total runs Under for -6.8 Units / -12.31% ROI
Cardinals vs Diamondbacks Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Corbin Carroll (ARI) | 0.5 +310 | 0.5 -400 |
| Ketel Marte (ARI) | 0.5 +360 | 0.5 -500 |
| Eugenio Suarez (ARI) | 0.5 +400 | 0.5 -525 |
| Nolan Gorman (STL) | 0.5 +575 | 0.5 -900 |
| Josh Naylor (ARI) | 0.5 +575 | 0.5 -900 |
Cardinals vs Diamondbacks Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Josh Naylor (ARI) | 0.5 -275 | 0.5 +195 |
| Ketel Marte (ARI) | 0.5 -275 | 0.5 +195 |
| Brendan Donovan (STL) | 0.5 -250 | 0.5 +190 |
| Masyn Winn (STL) | 0.5 -235 | 0.5 +175 |
| Eugenio Suarez (ARI) | 0.5 -225 | 0.5 +170 |
Cardinals vs Diamondbacks RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Corbin Carroll (ARI) | 0.5 +125 | 0.5 -160 |
| Ketel Marte (ARI) | 0.5 +130 | 0.5 -175 |
| Eugenio Suarez (ARI) | 0.5 +140 | 0.5 -190 |
| Lourdes Gurriel Jr (ARI) | 0.5 +160 | 0.5 -210 |
| Willson Contreras (STL) | 0.5 +165 | 0.5 -220 |
Cardinals vs Diamondbacks Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Zac Gallen (ARI) | 4.5 -150 | 4.5 +110 |
| Miles Mikolas (STL) | 3.5 +115 | 3.5 -150 |
Diamondbacks Starting Pitcher Stats & Trends
Zac Gallen has walked 17% of batters when going through the lineup the second time in a game this month (4 games) — tied for highest among qualified SPs in MLB; League Avg: 7% — third Percentile.
Zac Gallen has allowed an OPS of 1.082 (88 PA’s) versus the 2-3-4 hitters this season — 2nd highest among qualified SPs in MLB; League Avg: .721 — second Percentile.
Zac Gallen has allowed a slugging percentage of .684 (52 Total Bases / 76 ABs) versus the 2-3-4 hitters this season — 2nd highest among among NL Starters; League Avg: .407 — fourth Percentile.
Zac Gallen has allowed an OPS of 1.082 (88 PA’s) versus the 2-3-4 hitters this season — 2nd highest among among NL Starters; League Avg: .719 — fourth Percentile.
Cardinals Starting Pitcher Stats & Trends
Opponents batted .225 (89-for-396) against Miles Mikolas with two-strikes in 2023 — highest among qualified SPs in MLB; League Avg: .162 — second Percentile.
Opponents are hitting .225 (95-for-423) against Miles Mikolas with two-strikes since last season — 2nd highest among qualified SPs in MLB; League Avg: .161 — fourth Percentile.
Miles Mikolas allowed a slugging percentage of .519 (95 Total Bases / 183 ABs) on low non-fastballs in the 2024 season — highest among qualified SPs in MLB; League Avg: .302 — second Percentile.
Miles Mikolas allowed a slugging percentage of .554 (150 Total Bases / 271 ABs) when going through the lineup the second time in a game in the 2024 season — 2nd highest among qualified SPs in MLB; League Avg: .382 — third Percentile.
Diamondbacks Keys to the Game vs. the Cardinals
The Diamondbacks are 88-20 (.807) when allowing 4 or fewer runs since last season — 3rd best in MLB; League Avg: .719.
The Diamondbacks are 6-80 (.069) when trailing entering the 9th inning since last season — 5th best in MLB; League Avg: .048.
The Diamondbacks are just 19-6 (.760) when leading entering the 7th inning this season — 3rd lowest in MLB; League Avg: .873.
The Diamondbacks were 13-51 (.200) when trailing entering the 7th inning in the 2024 season — tied for 4th best in MLB; League Avg: .143.
Cardinals Keys to the Game vs. the Diamondbacks
The Cardinals are 89-5 (.947) when leading entering the 8th inning since last season — 3rd best in MLB; League Avg: .901.
The Cardinals are just 0-15 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .126.
The Cardinals are just 10-157 (.060) when trailing entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .098.
The Cardinals are just 16-145 (.099) when trailing entering the 7th inning since the 2023 season — 4th lowest in MLB; League Avg: .139.
Diamondbacks Hitting Stats & Trends
Diamondbacks hitters had an OBP of .347 (3,080 PA’s) at home in the 2024 season — best in MLB; League Avg: .315.
Diamondbacks hitters have an OBP of .347 (4,069 PA’s) at home since last season — best in MLB; League Avg: .317.
The Diamondbacks batted .284 against LHP in the 2024 season — best in MLB; League Avg: .245.
Diamondbacks hitters have struck out in just 17% of it’s PA’s against LHP this season — best in MLB; League Avg: 23%.
Cardinals Hitting Stats & Trends
The Cardinals have scored first in 77% of their road games this season — highest in MLB; League Avg: 55%.
The Cardinals are batting .189 on pitches out of the zone this season — best in MLB; League Avg: .148.
The Cardinals are batting .243 with two-strikes over the last 14 days — best in MLB; League Avg: .172.
Cardinals hitters struck out just 351 times in 1,755 PA’s (20%) against LHP in the 2024 season — tied for 5th best in MLB; League Avg: 23%.
Diamondbacks Pitching Stats & Trends
Opponents had a miss rate of just 24% against Diamondbacks pitchers in the 2024 season — tied for 4th lowest in MLB; League Avg: 25%.
The Diamondbacks pitchers have allowed their opponents to score first in just 34% of their games on the road since last season — lowest in MLB; League Avg: 44%.
Diamondbacks pitchers have 59 three-pitch strikeouts this season — 3rd fewest in MLB.
Diamondbacks pitchers have won 37% of games in which they have allowed their opponent to score in three different innings on the road since last season — highest in MLB; League Avg: 25%.
Cardinals Pitching Stats & Trends
Batters facing the Cardinals pitchers have struck out in the zone 46% of the time since last season — 2nd lowest in MLB; League Avg: 50%. since last season — 2nd lowest in MLB; League Avg: 50%.
The Cardinals pitchers have allowed their opponents to score first in just 23% of their games on the road this season — lowest in MLB; League Avg: 45%.
Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.
Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.
More MLB Reading:
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