Giants vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Apr 2

Houston Astros shortstop Jeremy Pena pops out during the first inning of a spring training baseball game against the New York Mets Thursday, Feb. 27, 2025, in Port St. Lucie, Fla.
(AP Photo/Jeff Roberson)
  • The Astros are -170 favorites vs the Giants
  • Giants vs Astros Over / Under today: 7.5 Runs
  • Giants / Astros TV Channel: NSBA | SCHN | MLBN

The San Francisco Giants (+140) visit Daikin Park to take on the Houston Astros (-170) on Wednesday, April 2, 2025. First pitch is scheduled for 4:10pm EDT in Houston, TX.

This season, the Giants are 4-1 against the spread (ATS), while the Astros are 1-4 ATS.

Giants vs Astros Starting Pitchers Today:

  • Giants starting pitcher: Landen Roupp 0-0, 0.00 ERA
  • Astros starting pitcher: Framber Valdez 1-0, 0.00 ERA

Giants vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants+1.5 -155O 7.5 -120+140
Astros -1.5 +125U 7.5 +100-170

Giants vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 59.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Wilmer Flores has hit the Home Runs Over in 3 of his last 5 games (+18.30 Units / 366% ROI)
  • Heliot Ramos has hit the Runs Over in his last 5 games (+6.25 Units / 119% ROI)
  • Jung Hoo Lee has hit the Hits Over in 13 of his last 20 away games (+6.15 Units / 17% ROI)
  • Patrick Bailey has hit the Total Bases Under in 7 of his last 9 away games (+6.00 Units / 51% ROI)
  • Jung Hoo Lee has hit the Hits Runs and RBIs Over in 7 of his last 8 away games (+5.80 Units / 63% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Christian Walker has hit the Runs Under in 18 of his last 25 games at home (+8.70 Units / 26% ROI)
  • Jose Altuve has hit the Home Runs Over in 1 of his last 3 games (+8.00 Units / 267% ROI)
  • Christian Walker has hit the RBIs Under in his last 8 games (+8.00 Units / 53% ROI)
  • Framber Valdez has hit the Earned Runs Under in 11 of his last 15 games (+7.10 Units / 35% ROI)
  • Christian Walker has hit the Hits Runs and RBIs Under in 16 of his last 25 games at home (+7.00 Units / 27% ROI)
  • The San Francisco Giants have hit the Game Total Over in 35 of their last 60 away games (+11.95 Units / 18% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 21 of their last 38 away games (+11.47 Units / 26% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 26 of their last 40 away games (+10.55 Units / 22% ROI)
  • The San Francisco Giants have hit the Moneyline in 18 of their last 29 away games (+10.35 Units / 32% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 away games (+9.33 Units / 16% ROI)
  • The Houston Astros have hit the Game Total Under in 85 of their last 146 games (+21.85 Units / 14% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 30 of their last 51 games (+16.20 Units / 20% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 73 of their last 124 games (+14.95 Units / 10% ROI)
  • The Houston Astros have covered the Run Line in 58 of their last 105 games (+13.15 Units / 10% ROI)
  • The Houston Astros have hit the Moneyline in 55 of their last 90 games (+8.25 Units / 6% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 5-0 against the Run Line (+6.15 Units / 87.86% ROI).

  • 4-1 when betting on the Moneyline for +3.05 Units / 53.04% ROI
  • 3-2 when betting on the total runs Over for +0.8 Units / 14.55% ROI
  • 2-3 when betting on the total runs Under for -1.3 Units / -23.64% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 1-4 against the Run Line (-2.65 Units / -48.62% ROI).

  • 2-3 when betting on the Moneyline for -1.4 Units / -24.35% ROI
  • 1-4 when betting on the total runs Over for -3.65 Units / -63.48% ROI
  • 4-1 when betting on the total runs Under for +2.9 Units / 55.24% ROI

Astros vs Giants Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +320 0.5 -400
Matt Chapman (SF) 0.5 +375 0.5 -500
Christian Walker (HOU) 0.5 +400 0.5 -525
Heliot Ramos (SF) 0.5 +475 0.5 -700
Willy Adames (SF) 0.5 +500 0.5 -700

Astros vs Giants Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -275 0.5 +200
Heliot Ramos (SF) 0.5 -250 0.5 +180
Jose Altuve (HOU) 0.5 -225 0.5 +170
Yordan Alvarez (HOU) 0.5 -220 0.5 +160
Jeremy Pena (HOU) 0.5 -210 0.5 +160

Astros vs Giants RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +145 0.5 -190
Christian Walker (HOU) 0.5 +150 0.5 -200
Matt Chapman (SF) 0.5 +160 0.5 -210
Yainer Diaz (HOU) 0.5 +165 0.5 -220
Wilmer Flores (SF) 0.5 +195 0.5 -275

Astros vs Giants Strikeout Prop Bets Today

Over Under
Framber Valdez (HOU) 5.5 -155 5.5 +115

Left-handed hitters have a swing rate of just 37% (175/470) against Landen Roupp since last season — lowest among qualified RPs in MLB*; League Avg: 48% — 0 Percentile.

Landen Roupp threw his curveball 37% of the time (80/214) when behind in the count in the 2024 season — 2nd highest among qualified RPs in MLB*; League Avg: 11% — 98th Percentile.

Landen Roupp has thrown his curveball 37% of the time (80/214) when he’s behind in the count since last season — 2nd highest among qualified RPs in MLB*; League Avg: 11% — 98th Percentile.

Opponents are hitting .478 (11-for-23) against Landen Roupp on the first pitch of at-bats since last season — 5th highest among NL Relievers; League Avg: .326 — sixth Percentile.

Astros Starting Pitcher Stats & Trends

Opponents had a groundball rate of 61% (291/473) against Framber Valdez in the 2024 season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Framber Valdez has thrown inside pitches 43% of the time (319/736) with two-strikes since last season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

Framber Valdez located 42% of his pitches inside (302/710) with two-strikes in the 2024 season — highest among qualified SPs in MLB; League Avg: 29% — 100th Percentile.

Opponents have a groundball rate of 61% (300/492) against Framber Valdez since last season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Giants Keys to the Game vs. the Astros

The Giants are 135-4 (.971) when leading entering the 9th inning since last season — 4th best in MLB; League Avg: .950.

The Giants are 23-139 (.142) when trailing entering the 8th inning since last season — 4th best in MLB; League Avg: .099.

The Giants are 11-144 (.071) when trailing entering the 9th inning since last season — 5th best in MLB; League Avg: .050.

The Giants were just 20-24 (.455) vs bottom 10 scoring offenses in the 2024 season They play the Astros (10th best runs scored) today.

Astros Keys to the Game vs. the Giants

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

The Astros are just 12-23 (.343) when tied entering the 8th inning since last season — 3rd lowest in MLB; League Avg: .500.

The Astros are 45-41 (.523) vs top 10 scoring offenses since last season They play the Giants (17th best runs scored) today.

The Giants batted just .151 with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .172.

Giants hitters had an OPS of just .475 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .523.

Giants hitters had an OBP of just .232 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .249.

The Giants are batting just .217 with two outs since last season — 3rd lowest in MLB; League Avg: .233.

Astros hitters struck out just 327 times in 1,801 PA’s (18%) against LHP in 2023 — tied for best in MLB; League Avg: 23%.

Astros hitters are averaging just 3.67 pitches per plate appearance since last season — lowest in MLB; League Avg: 3.89.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters are slugging .491 in lefty-lefty matchups since the 2023 season — best in MLB; League Avg: .371.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Astros pitchers walked 544 of 6,019 batters (9%) in the 2024 season — 4th highest in MLB; League Avg: 8%.

Astros pitchers have a strikeout rate of 28% this season — 5th best in MLB; League Avg: 23%.

Opponents had a miss rate of 27% against Astros pitchers in the 2024 season — 2nd best in MLB; League Avg: 25%.

Astros pitchers had a strikeout rate of 25% in the 2024 season — 3rd best in MLB; League Avg: 23%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.