Giants vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, May 7

Chicago Cubs' Dansby Swanson waves to the crowd before batting against his former team the Atlanta Braves in the second inning of a baseball game, Tuesday, Sept. 26, 2023, in Atlanta.
(AP Photo/John Bazemore)
  • The Cubs are -140 favorites vs the Giants
  • Giants vs Cubs Over / Under today: 7 Runs
  • Giants / Cubs TV Channel: MARQ | NSBA

The San Francisco Giants (+115) visit Wrigley Field to take on the Chicago Cubs (-140) on Wednesday, May 7, 2025. First pitch is scheduled for 2:20pm EDT in Chicago, IL, IL.

This season, the Giants are 23-14 against the spread (ATS), while the Cubs are 20-17 ATS.

Giants vs Cubs Starting Pitchers Today:

  • Giants starting pitcher: Robbie Ray 4-0, 3.08 ERA
  • Cubs starting pitcher: Ben Brown 3-2, 4.89 ERA

Giants vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants+1.5 -185O 7 -105+115
Cubs -1.5 +155U 7 -115-140

Giants vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Wednesday‘s MLB game with 53.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Heliot Ramos has hit the Runs Over in 15 of his last 20 away games (+15.40 Units / 75% ROI)
  • Heliot Ramos has hit the Hits Runs and RBIs Over in 15 of his last 20 away games (+9.80 Units / 42% ROI)
  • Heliot Ramos has hit the Home Runs Over in 2 of his last 6 games (+8.10 Units / 135% ROI)
  • Heliot Ramos has hit the Total Bases Over in 13 of his last 20 away games (+7.65 Units / 32% ROI)
  • Jung Hoo Lee has hit the Singles Over in 9 of his last 10 games (+7.55 Units / 57% ROI)

And here are some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Pete Crow-Armstrong has hit the Home Runs Over in 3 of his last 8 games (+16.90 Units / 211% ROI)
  • Pete Crow-Armstrong has hit the Runs Over in 15 of his last 25 games (+13.35 Units / 53% ROI)
  • Dansby Swanson has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+9.35 Units / 53% ROI)
  • Justin Turner has hit the Hits Over in 19 of his last 25 games (+8.35 Units / 19% ROI)
  • Kyle Tucker has hit the RBIs Over in 6 of his last 8 games (+8.00 Units / 100% ROI)
  • The San Francisco Giants have hit the Game Total Over in 14 of their last 18 away games (+10.60 Units / 54% ROI)
  • The San Francisco Giants have hit the Team Total Over in 12 of their last 18 away games (+6.00 Units / 30% ROI)
  • The San Francisco Giants have hit the Moneyline in 22 of their last 35 games (+5.85 Units / 12% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 20 away games (+5.05 Units / 21% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 12 of their last 19 away games (+3.75 Units / 16% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 26 of their last 33 games (+18.55 Units / 47% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 24 of their last 35 games (+16.70 Units / 36% ROI)
  • The Chicago Cubs have hit the Team Total Over in 22 of their last 32 games (+10.60 Units / 28% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 31 games (+9.80 Units / 27% ROI)
  • The Chicago Cubs have hit the Game Total Over in 12 of their last 15 games at home (+8.80 Units / 55% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 18-19 against the Run Line (-0.35 Units / -0.73% ROI).

  • 23-14 when betting on the Moneyline for +5.8 Units / 11.02% ROI
  • 22-14 when betting on the total runs Over for +6.65 Units / 16.52% ROI
  • 14-22 when betting on the total runs Under for -10.55 Units / -25.64% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 20-17 against the Run Line (+4.7 Units / 10.28% ROI).

  • 22-15 when betting on the Moneyline for +5.15 Units / 11.1% ROI
  • 22-13 when betting on the total runs Over for +8 Units / 20.08% ROI
  • 13-22 when betting on the total runs Under for -11.65 Units / -28.04% ROI

Cubs vs Giants Home Run Prop Bets Today

Over Under
Kyle Tucker (CHC) 0.5 +475 0.5 -650
Matt Chapman (SF) 0.5 +550 0.5 -800
Willy Adames (SF) 0.5 +600 0.5 -900
Seiya Suzuki (CHC) 0.5 +625 0.5 -1000
Mike Yastrzemski (SF) 0.5 +675 0.5 -1100

Cubs vs Giants Total Hits Prop Bets Today

Over Under
Nico Hoerner (CHC) 0.5 -225 0.5 +170
Jung-hoo Lee (SF) 0.5 -225 0.5 +170
Kyle Tucker (CHC) 0.5 -190 0.5 +140
Willy Adames (SF) 0.5 -175 0.5 +130
Heliot Ramos (SF) 0.5 -175 0.5 +135

Cubs vs Giants RBI Prop Bets Today

Over Under
Carson Kelly (CHC) 0.5 +180 0.5 -235
Matt Chapman (SF) 0.5 +185 0.5 -250
Seiya Suzuki (CHC) 0.5 +190 0.5 -250
Kyle Tucker (CHC) 0.5 +200 0.5 -275
Dansby Swanson (CHC) 0.5 +200 0.5 -275

Cubs vs Giants Strikeout Prop Bets Today

Over Under
Ben Brown (CHC) 5.5 -118 5.5 -110
Robbie Ray (SF) 5.5 -110 5.5 -118

Robbie Ray has walked 17% of batters when going through the lineup the first time in a game this season — tied for 2nd highest among qualified SPs in MLB; League Avg: 8% — third Percentile.

Robbie Ray has walked 17% of batters when going through the lineup the first time in a game this season — tied for 2nd highest among among NL Starters; League Avg: 8% — sixth Percentile.

Robbie Ray has walked 13% of batters this season — highest among among NL Starters; League Avg: 7% — second Percentile.

Robbie Ray has walked 13% of batters this season — highest among qualified SPs in MLB; League Avg: 8% — first Percentile.

Cubs Starting Pitcher Stats & Trends

Ben Brown has thrown his curveball 36% of the time (42/118) when he’s behind in the count this season — 2nd highest in MLB among starting pitchers with at least 13 total CB; League Avg: 10% — 98th Percentile.

Ben Brown has thrown his curveball 40% of the time (222/557) this season — 2nd highest in MLB among starting pitchers with at least 13 total CB; League Avg: 15% — 99th Percentile.

Ben Brown has allowed a BABIP of .463 vs left-handed batters this season — highest in MLB among starting pitchers with at least 13 total IP; League Avg: .281 — first Percentile.

Ben Brown has thrown his curveball 41% of the time (113/276) against right-handed batters this season — 2nd highest in MLB among starting pitchers with at least 13 total CB; League Avg: 13% — 98th Percentile.

Giants Keys to the Game vs. the Cubs

The Giants are 3-11 (.214) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .083.

The Giants are 25-149 (.144) when trailing entering the 8th inning since the 2023 season — 4th best in MLB; League Avg: .098.

The Giants are 16-0 (1.000) when scoring 5 or more runs this season — tied for best in MLB; League Avg: .833.

The Giants are 23-14 (.622) this season — tied for 4th best in MLB; League Avg: .500.

Cubs Keys to the Game vs. the Giants

The Cubs are 11-3 (.786) after a loss this season — best in MLB; League Avg: .499.

The Cubs are 14-1 (.933) when they’ve had 10 or more hits this season — best in MLB; League Avg: .740.

The Cubs are 80-49 (.620) vs bottom 10 scoring offenses since the 2023 season They play the Giants (17th best runs scored) today.

The Cubs are 12-7 (.632) on the road this season — 2nd best in MLB; League Avg: .414.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .742.

The Giants batted just .151 with two-strikes in the 2023 season — 2nd lowest in MLB; League Avg: .172.

Giants hitters have struck out in 25% of it’s PA’s against LHP since last season — 5th highest in MLB; League Avg: 23%.

Giants hitters struck out 453 times in 1,790 PA’s (25%) against LHP in 2023 — 3rd highest in MLB; League Avg: 23%.

Cubs hitters have an OPS of .865 (350 PA’s) against LHP this season — 2nd best in MLB; League Avg: .681.

Cubs hitters are slugging .503 against LHP this season — 2nd best in MLB; League Avg: .372.

Cubs hitters are slugging .273 on pitches out of the zone this season — best in MLB; League Avg: .200.

Cubs hitters have an OPS of .836 (773 PA’s) on the road this season — best in MLB; League Avg: .686.

Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Cubs pitchers this season — 4th lowest in MLB; League Avg: 43%.

The Cubs allowed 3.41 runs per game (276/81) at home in the 2024 season — 2nd best in MLB; League Avg: 4.41.

Cubs pitchers have walked 9% of batters when facing the leadoff batter in the inning since last season — 2nd highest in MLB; League Avg: 8%.

Cubs pitchers induced opposing hitters to ground into just 80 double plays in 1,126 opportunities (7%) in the 2024 season — 2nd lowest in MLB; League Avg: 10%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.