Giants vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Apr 30

San Diego Padres' Jake Cronenworth during a baseball game against the San Francisco Giants in San Francisco, Wednesday, June 21, 2023.
(AP Photo/Jeff Chiu)
  • The Padres are -140 favorites vs the Giants
  • Giants vs Padres Over / Under today: 7 Runs
  • Giants / Padres TV Channel: NSBA | PDTV

The San Francisco Giants (+125) visit Petco Park to take on the San Diego Padres (-150) on Wednesday, April 30, 2025. First pitch is scheduled for 4:10pm EDT in San Diego, CA, CA.

This season, the Giants are 19-11 against the spread (ATS), while the Padres are 16-13 ATS.

Giants vs Padres Starting Pitchers Today:

  • Giants starting pitcher: Landen Roupp 2-1, 4.56 ERA
  • Padres starting pitcher: Michael King 3-1, 2.16 ERA

Giants vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants+1.5 -190O 7 -115+125
Padres -1.5 +155U 7 -105-150

Giants vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Heliot Ramos has hit the Runs Over in 11 of his last 15 away games (+10.45 Units / 69% ROI)
  • Jung Hoo Lee has hit the Home Runs Over in 2 of his last 10 away games (+10.00 Units / 100% ROI)
  • Matt Chapman has hit the Hits Under in 12 of his last 20 games (+9.25 Units / 46% ROI)
  • Matt Chapman has hit the RBIs Under in 16 of his last 20 games (+9.10 Units / 25% ROI)
  • Tyler Fitzgerald has hit the Singles Over in 9 of his last 15 away games (+7.80 Units / 52% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Jose Iglesias has hit the Hits Over in 20 of his last 25 games at home (+13.55 Units / 28% ROI)
  • Luis Arraez has hit the Total Bases Under in 17 of his last 20 games at home (+12.30 Units / 36% ROI)
  • Fernando Tatis Jr. has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+10.20 Units / 33% ROI)
  • Jason Heyward has hit the Singles Under in 13 of his last 15 games at home (+9.05 Units / 29% ROI)
  • Xander Bogaerts has hit the Home Runs Over in 1 of his last 4 games (+9.00 Units / 225% ROI)
  • The San Francisco Giants have hit the Game Total Over in 11 of their last 15 away games (+7.60 Units / 46% ROI)
  • The San Francisco Giants have hit the Team Total Over in 11 of their last 15 away games (+7.00 Units / 42% ROI)
  • The San Francisco Giants have hit the Moneyline in 18 of their last 28 games (+6.30 Units / 18% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 12 games (+5.75 Units / 37% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 11 of their last 16 away games (+5.15 Units / 26% ROI)
  • The San Diego Padres have covered the Run Line in 12 of their last 15 games at home (+10.60 Units / 59% ROI)
  • The San Diego Padres have hit the Moneyline in 13 of their last 17 games at home (+8.40 Units / 35% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 11 of their last 15 games at home (+6.60 Units / 37% ROI)
  • The San Diego Padres have hit the Game Total Under in 11 of their last 15 games at home (+6.45 Units / 38% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 25 games (+5.42 Units / 18% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 14-16 against the Run Line (+0.1 Units / 0.27% ROI).

  • 19-11 when betting on the Moneyline for +6.25 Units / 16.73% ROI
  • 17-12 when betting on the total runs Over for +3.85 Units / 11.79% ROI
  • 12-17 when betting on the total runs Under for -6.95 Units / -20.84% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 16-13 against the Run Line (+1.15 Units / 2.97% ROI).

  • 18-11 when betting on the Moneyline for +6.4 Units / 17.18% ROI
  • 11-17 when betting on the total runs Over for -7.25 Units / -23.2% ROI
  • 17-11 when betting on the total runs Under for +4.5 Units / 13.74% ROI

Padres vs Giants Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +360 0.5 -500
Matt Chapman (SF) 0.5 +475 0.5 -650
Willy Adames (SF) 0.5 +500 0.5 -700
Manny Machado (SD) 0.5 +550 0.5 -800
Mike Yastrzemski (SF) 0.5 +575 0.5 -900

Padres vs Giants Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -235 0.5 +180
Jose Iglesias (SD) 0.5 -235 0.5 +175
Jung-hoo Lee (SF) 0.5 -220 0.5 +160
Xander Bogaerts (SD) 0.5 -175 0.5 +130
Heliot Ramos (SF) 0.5 -175 0.5 +130

Padres vs Giants RBI Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +150 0.5 -200
Manny Machado (SD) 0.5 +170 0.5 -225
Luis Arraez (SD) 0.5 +190 0.5 -250
Gavin Sheets (SD) 0.5 +210 0.5 -295
Matt Chapman (SF) 0.5 +210 0.5 -285

Padres vs Giants Strikeout Prop Bets Today

Over Under
Michael King (SD) 6.5 -130 6.5 +100
Landen Roupp (SF) 4.5 +100 4.5 -130

Landen Roupp threw his curveball 37% of the time (80/214) when behind in the count in the 2024 season — 2nd highest among qualified RPs in MLB*; League Avg: 11% — 98th Percentile.

Left-handed hitters had a swing rate of just 37% (175/470) against Landen Roupp in the 2024 season — lowest among qualified RPs in MLB*; League Avg: 48% — first Percentile.

Landen Roupp has thrown his curveball 47% of the time (121/258) against right-handed batters this season — highest in MLB among starting pitchers with at least 11 total CB; League Avg: 13% — 100th Percentile.

Landen Roupp walked 19 of 103 left-handed batters (18%) in the 2024 season — tied for 4th highest among NL Relievers; League Avg: 9% — fifth Percentile.

Padres Starting Pitcher Stats & Trends

Michael King has a strikeout rate of 50% (10 SO in 20 PAs) in PAs ending on elevated fastballs this season — 2nd best among qualified SPs in MLB; League Avg: 23% — 98th Percentile.

Michael King has a strike rate of just 61% (151/249) against right-handed batters this season — 6th lowest among qualified SPs in MLB; League Avg: 65% — seventh Percentile.

Michael King has allowed an OPS of just .428 (54 PA’s) when going through the lineup the first time in a game this season — 3rd best among qualified SPs in MLB; League Avg: .685 — 97th Percentile.

Michael King had a strikeout rate of 33% (92/279) when going through the lineup the first time in a game in the 2024 season — tied for 2nd best among qualified SPs in MLB; League Avg: 25% — 98th Percentile.

Giants Keys to the Game vs. the Padres

The Giants are 8-2 (.800) after a loss this season — 2nd best in MLB; League Avg: .508.

The Giants are 3-9 (.250) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .080.

The Giants are 3-9 (.250) when trailing entering the 7th inning this season — tied for 2nd best in MLB; League Avg: .109.

The Giants are 7-1 (.875) when they’ve scored in the first inning this season — best in MLB; League Avg: .618.

Padres Keys to the Game vs. the Giants

The Padres were 66-8 (.892) when they scored 5 or more runs in the 2024 season — 2nd best in MLB; League Avg: .804.

The Padres are 9-2 (.818) when they’ve scored in the first inning this season — 4th best in MLB; League Avg: .618.

The Padres are 22-16 (.579) when tied entering the 7th inning since the 2023 season — 4th best in MLB; League Avg: .499.

The Padres were 13-8 (.619) when tied entering the 7th inning in the 2024 season — 5th best in MLB; League Avg: .498.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .742.

Giants hitters had an OPS of just .475 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .523.

Giants hitters had an OBP of just .232 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .249.

The Giants batted just .151 with two-strikes in the 2023 season — 2nd lowest in MLB; League Avg: .172.

Padres hitters have struck out in just 17% of it’s PA’s against LHP since last season — best in MLB; League Avg: 23%.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of it’s PA’s since last season — best in MLB; League Avg: 23%.

Padres hitters have struck out in 50% of it’s PA’s against LHP over the past seven days (3 games) — highest in MLB; League Avg: 21%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 48% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

The Padres have allowed 0.48 runs per game (14/29) in late innings this season — best in MLB; League Avg: 1.30.

The Padres pitchers have allowed their opponents to score first in just 30% of their games since last season — tied for lowest in MLB; League Avg: 50%.

Opponents have a groundball rate of just 39% against Padres pitchers this season — 5th lowest in MLB; League Avg: 43%.

The Padres pitchers have allowed their opponents to score first in just 31% of their games this season — 2nd lowest in MLB; League Avg: 50%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.