Guardians vs Angels Prediction, Odds & Player Prop Bets Today – MLB, Apr 4

Los Angeles Angels third baseman Anthony Rendon throws the ball into the crowd in the first inning of a baseball game against the Texas Rangers, Tuesday, June 13, 2023, in Arlington, Texas.
AP Photo/Gareth Patterson
  • The Guardians are -120 favorites vs the Angels
  • Guardians vs Angels Over / Under today: 7.5 Runs
  • Guardians / Angels TV Channel: FDW | GDTV | MLBN

The Cleveland Guardians (-115) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (-105) on Friday, April 4, 2025. First pitch is scheduled for 9:38pm EDT in Anaheim, CA.

This season, the Guardians are 2-4 against the spread (ATS), while the Angels are 2-4 ATS.

Guardians vs Angels Starting Pitchers Today:

  • Guardians starting pitcher: Gavin Williams 0-0, 3.60 ERA
  • Angels starting pitcher: Jose Soriano 1-0, 0.00 ERA

Guardians vs. Angels Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-1.5 +145O 8 -115-115
Angels +1.5 -175U 8 -105-105

Guardians vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Friday‘s MLB game with 52.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Steven Kwan has hit the Total Bases Over in 9 of his last 10 away games (+9.75 Units / 68% ROI)
  • Kyle Manzardo has hit the Home Runs Over in 2 of his last 5 games (+9.30 Units / 186% ROI)
  • Lane Thomas has hit the Runs Under in his last 9 away games (+9.00 Units / 55% ROI)
  • Lane Thomas has hit the Hits Over in 16 of his last 20 away games (+8.40 Units / 21% ROI)
  • Gavin Williams has hit the Hits Allowed Under in 9 of his last 10 away games (+8.05 Units / 66% ROI)

And here are some favorite MLB player prop bets for Angels players for Friday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

  • Logan O’Hoppe has hit the Home Runs Over in 2 of his last 4 games (+8.70 Units / 217% ROI)
  • Nicky Lopez has hit the Singles Over in 11 of his last 15 games at home (+5.15 Units / 25% ROI)
  • Nolan Schanuel has hit the Total Bases Over in his last 4 games (+4.90 Units / 92% ROI)
  • Mike Trout has hit the RBIs Over in his last 3 games (+4.50 Units / 150% ROI)
  • Jose Soriano has hit the Walks Allowed Over in his last 4 games at home (+4.40 Units / 70% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 47 of their last 79 games (+17.00 Units / 19% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 6 of their last 7 games (+5.60 Units / 69% ROI)
  • The Cleveland Guardians have hit the Moneyline in 91 of their last 164 games (+5.55 Units / 3% ROI)
  • The Cleveland Guardians have covered the Run Line in 23 of their last 43 games (+3.45 Units / 6% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 21 of their last 32 games at home (+8.15 Units / 21% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 19 of their last 29 games (+8.05 Units / 23% ROI)
  • The Los Angeles Angels have hit the Game Total Under in 30 of their last 56 games at home (+7.35 Units / 12% ROI)
  • The Los Angeles Angels have covered the Run Line in 34 of their last 61 games at home (+6.05 Units / 8% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 3-3 against the Run Line (-1.7 Units / -16.5% ROI).

  • 2-4 when betting on the Moneyline for -1.55 Units / -25.2% ROI
  • 3-3 when betting on the total runs Over for -0.15 Units / -2.33% ROI
  • 3-3 when betting on the total runs Under for -0.3 Units / -4.44% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 2-4 against the Run Line (-2.65 Units / -33.54% ROI).

  • 4-2 when betting on the Moneyline for +1.95 Units / 26.17% ROI
  • 4-2 when betting on the total runs Over for +1.8 Units / 27.07% ROI
  • 2-4 when betting on the total runs Under for -2.35 Units / -35.88% ROI

Angels vs Guardians Home Run Prop Bets Today

Over Under
Mike Trout (LAA) 0.5 +375 0.5 -500
Jorge Soler (LAA) 0.5 +450 0.5 -650
Taylor Ward (LAA) 0.5 +575 0.5 -900
Jo Adell (LAA) 0.5 +575 0.5 -900
Logan O'Hoppe (LAA) 0.5 +600 0.5 -900

Angels vs Guardians Total Hits Prop Bets Today

Over Under
Steven Kwan (CLE) 0.5 -235 0.5 +180
Jose Ramirez (CLE) 0.5 -225 0.5 +170
Luis Rengifo (LAA) 0.5 -210 0.5 +155
Taylor Ward (LAA) 0.5 -210 0.5 +155
Mike Trout (LAA) 0.5 -185 0.5 +135

Angels vs Guardians RBI Prop Bets Today

Over Under
Mike Trout (LAA) 0.5 +165 0.5 -220
Jorge Soler (LAA) 0.5 +165 0.5 -220
Kyle Manzardo (CLE) 0.5 +195 0.5 -275
Jose Ramirez (CLE) 0.5 +210 0.5 -285
Carlos Santana (CLE) 0.5 +220 0.5 -295

Angels vs Guardians Strikeout Prop Bets Today

Over Under
Josรฉ Soriano (LAA) 4.5 -125 4.5 -105
Gavin Williams (CLE) 5.5 +110 5.5 -145

Opponents have a chase percentage of 41% (9/22) against Gavin Williams in non-two strike counts this season — highest in MLB among starting pitchers with at least 2 total IP; League Avg: 24% — 100th Percentile.

21 of Gavin Williams’ 74 breaking pitch strikeouts (28%) have been backdoor since the 2023 season — 2nd highest in MLB among starting pitchers with at least 131 total IP; League Avg: 14% — 99th Percentile.

Opponents had a Hard-Hit Rate of 50% (20/40) against Gavin Williams on low breaking pitches in the 2024 season — tied for highest in MLB among starting pitchers with at least 64 total IP; League Avg: 32% — first Percentile.

Opponents had a groundball batting average of just .165 (14 GB hits out of 85 GBs) against Gavin Williams in 2023 — 9th best in MLB among starting pitchers with at least 64 total IP; League Avg: .246 — 95th Percentile.

Angels Starting Pitcher Stats & Trends

Opponents have a groundball rate of 75% (12/16) against Jose Soriano this season — highest among qualified SPs in MLB; League Avg: 44% — 100th Percentile.

Jose Soriano had a strikeout rate of 60% (56/94) with two-strikes in 2023 — 4th best among AL Relievers; League Avg: 46% — 97th Percentile.

Jose Soriano has allowed a slugging percentage of just .250 (78 Total Bases / 312 ABs) vs left-handed batters since the 2023 season — best in MLB among starting pitchers with at least 131 total IP; League Avg: .414 — 100th Percentile.

Jose Soriano allowed a slugging percentage of just .147 (10 Total Bases / 68 ABs) vs left-handed batters in 2023 — best among AL Relievers; League Avg: .367 — 100th Percentile.

Guardians Keys to the Game vs. the Angels

The Guardians were just 3-61 (.047) when trailing entering the 8th inning in the 2024 season — 2nd lowest in MLB; League Avg: .100.

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians were 66-9 (.880) when they scored 5 or more runs in the 2024 season — tied for 3rd best in MLB; League Avg: .804.

The Guardians were 44-11 (.800) when they hit 2 or more home runs in the 2024 season — 5th best in MLB; League Avg: .711.

Angels Keys to the Game vs. the Guardians

The Angels are just 118-13 (.901) when leading entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .950.

The Angels were just 54-6 (.900) when leading entering the 9th inning in the 2024 season — 2nd lowest in MLB; League Avg: .949.

The Angels were just 12-74 (.140) when they allowed 5 or more runs in the 2024 season — 3rd lowest in MLB; League Avg: .196.

The Angels are just 107-19 (.849) when leading entering the 8th inning since last season — 3rd lowest in MLB; League Avg: .900.

The Guardians batted just .232 against LHP in 2023 — tied for lowest in MLB; League Avg: .254.

Guardians hitters slugged just .367 against LHP in 2023 — lowest in MLB; League Avg: .419.

Guardians hitters had a Hard-Hit Rate of just 33% in the 2023 season — lowest in MLB; League Avg: 40%.

Guardians hitters have put just 34% of balls in play to the left side of the field since the 2023 season — lowest in MLB; League Avg: 38%.

The Angels scored first in just 25% of their home games last season — lowest in MLB; League Avg: 44%.

The Angels had a winning percentage of just 40% at home last season — 3rd lowest in MLB; League Avg: 52%.

The Angels have scored first in just 31% of their home games since the 2023 season — lowest in MLB; League Avg: 44%.

Angels hitters had an OBP of just .269 (485 PA’s) against pitchers who had thrown at least 80 pitches in a game in 2023 — lowest in MLB; League Avg: .322.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Opponents have a groundball batting average of just .209 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .262.

Opponents have a miss rate of just 21% against Guardians pitchers this season — lowest in MLB; League Avg: 27%.

Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.

Angels pitchers walked 135 of 1,436 batters (9%) when facing the leadoff batter in the inning in the 2024 season — highest in MLB; League Avg: 7%.

Angels pitchers have walked 138 of 1,491 batters (9%) when facing the leadoff batter in the inning since last season — highest in MLB; League Avg: 8%.

Angels pitchers walked 150 of 1,434 batters (10%) when facing the leadoff batter in the inning in 2023 — highest in MLB; League Avg: 8%.

Angels pitchers have walked 288 of 2,925 batters (10%) when facing the leadoff batter in the inning since the 2023 season — highest in MLB; League Avg: 8%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.