Guardians vs Twins Prediction, Odds & Player Prop Bets Today – MLB, Apr 6

Minnesota Twins' Max Kepler celebrates while crossing home plate to score the game-winning run against the San Diego Padres during the 11th inning of a baseball game Wednesday, May 10, 2023, in Minneapolis. (AP Photo/Abbie Parr)
(AP Photo/Abbie Parr)
  • The Twins are -165 favorites vs the Guardians
  • Guardians vs Twins Over / Under today: 8 Runs
  • Guardians / Twins TV Channel: BSGL | BSNX

The Cleveland Guardians (+140) visit Target Field to take on the Minnesota Twins (-165) on Saturday, April 6, 2024. First pitch is scheduled for 2:10pm EDT in Minneapolis, MN.

This season, the Guardians are 6-2 against the spread (ATS), while the Twins are 3-3 ATS.

Guardians vs Twins Starting Pitchers Today:

  • Guardians starting pitcher: Carlos Carrasco 0-0, 5.40 ERA
  • Twins starting pitcher: Joe Ryan 0-0, 1.69 ERA

Guardians vs. Twins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -145O 8 -120+140
Twins -1.5 +120U 8 +100-165

Guardians vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Saturday‘s MLB game with 55.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Myles Straw has hit the Runs Under in his last 11 away games (+11.00 Units / 40% ROI)
  • Andres Gimenez has hit the Hits Over in 16 of his last 19 away games (+10.20 Units / 25% ROI)
  • Estevan Florial has hit the Singles Over in 10 of his last 15 away games (+10.10 Units / 67% ROI)
  • Tanner Bibee has hit the Earned Runs Under in 18 of his last 24 games (+9.75 Units / 32% ROI)
  • Steven Kwan has hit the Hits Over in 12 of his last 22 away games (+9.00 Units / 36% ROI)

And here are some favorite MLB player prop bets for Twins players for Saturday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

  • Kyle Farmer has hit the Hits Over in 21 of his last 25 games at home (+12.10 Units / 23% ROI)
  • Kyle Farmer has hit the Total Bases Over in 18 of his last 25 games at home (+11.20 Units / 29% ROI)
  • Matt Wallner has hit the Hits Runs and RBIs Under in 15 of his last 20 games at home (+9.40 Units / 33% ROI)
  • Kyle Farmer has hit the Hits Runs and RBIs Over in 14 of his last 19 games at home (+9.15 Units / 43% ROI)
  • Max Kepler has hit the Hits Runs and RBIs Under in 10 of his last 11 games (+9.00 Units / 67% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 85 of their last 146 games (+21.85 Units / 14% ROI)
  • The Cleveland Guardians have covered the Run Line in 34 of their last 60 away games (+6.30 Units / 8% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 34 games (+4.72 Units / 12% ROI)
  • The Cleveland Guardians have hit the Team Total Over in 22 of their last 39 away games (+2.24 Units / 5% ROI)
  • The Minnesota Twins have covered the Run Line in 31 of their last 50 games (+14.40 Units / 24% ROI)
  • The Minnesota Twins have hit the Game Total Over in 47 of their last 78 games (+13.95 Units / 16% ROI)
  • The Minnesota Twins have hit the Team Total Over in 48 of their last 77 games (+13.50 Units / 15% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 25 of their last 40 games at home (+7.65 Units / 16% ROI)
  • The Minnesota Twins have hit the Moneyline in 28 of their last 45 games at home (+2.85 Units / 4% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 6-2 against the Run Line (+4.85 Units / 46.86% ROI).

  • 6-2 when betting on the Moneyline for +4.4 Units / 46.56% ROI
  • 5-2 when betting on the total runs Over for +2.75 Units / 31.25% ROI
  • 2-5 when betting on the total runs Under for -3.7 Units / -41.81% ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 3-3 against the Run Line (+1.25 Units / 20.83% ROI).

  • 3-3 when betting on the Moneyline for -0.85 Units / -11.49% ROI
  • 2-4 when betting on the total runs Over for -2.5 Units / -35.97% ROI
  • 4-2 when betting on the total runs Under for +2 Units / 31.75% ROI

Twins vs Guardians Home Run Prop Bets Today

Over Under
Buxton 0.5 +375 0.5 -550
Kirilloff 0.5 +550 0.5 -800
Brennan 0.5 +950 0.5 -2000
Freeman 0.5 +1000 0.5 -2000
Kwan 0.5 +1150 0.5 -3000

Twins vs Guardians Strikeout Prop Bets Today

Over Under
Carrasco 5.5 +140 5.5 -190

Carlos Carrasco has allowed a slugging percentage of .766 (98 Total Bases / 128 ABs) on inside fastballs since the 2022 season — highest in MLB among starting pitchers with at least 132 total IP; League Avg: .430 — 0 Percentile.

Opponents are hitting .414 (53-for-128) against Carlos Carrasco’s inside fastball since the 2022 season — highest in MLB among starting pitchers with at least 132 total IP; League Avg: .262 — 0 Percentile.

Opponents batted .426 (20-for-47) against Carlos Carrasco on low fastballs in the 2023 season — 2nd highest in MLB among starting pitchers with at least 64 total IP; League Avg: .274 — first Percentile.

Carlos Carrasco has allowed a slugging percentage of .843 (43 Total Bases / 51 ABs) on low fastballs since last season — highest in MLB among starting pitchers with at least 67 total IP; League Avg: .428 — 0 Percentile.

Twins Starting Pitcher Stats & Trends

Opponents had a groundball rate of just 33% (144/435) against Joe Ryan in the 2023 season — 3rd lowest among qualified SPs in MLB; League Avg: 43% — sixth Percentile.

Left-handed hitters have a swing rate of 56% (723/1,284) against Joe Ryan since last season — highest in MLB among starting pitchers with at least 67 total IP; League Avg: 47% — 100th Percentile.

Joe Ryan had a strike rate of 71% (884/1,249) vs left-handed batters in the 2023 season — 2nd highest in MLB among starting pitchers with at least 64 total IP; League Avg: 63% — 98th Percentile.

Joe Ryan had a strike rate of 69% (1,849/2,683) in the 2023 season — tied for 3rd highest among qualified SPs in MLB; League Avg: 65% — 95th Percentile.

Guardians Keys to the Game vs. the Twins

The Guardians are 34-115 (.227) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .130.

The Guardians were just 5-15 (.250) when tied entering the 8th inning in 2023 — 2nd lowest in MLB; League Avg: .500.

The Guardians were just 5-15 (.250) when tied entering the 7th inning in 2023 — lowest in MLB; League Avg: .500.

The Guardians are just 5-15 (.250) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .496.

Twins Keys to the Game vs. the Guardians

The Twins are just 14-27 (.341) when tied entering the 7th inning since the 2022 season — lowest in MLB; League Avg: .497.

The Twins were 33-11 (.750) when they scored in the first inning in 2023 — 2nd best in MLB; League Avg: .612.

The Twins are 18-53 (.254) when trailing entering the 7th inning since the 2023 season — best in MLB; League Avg: .141.

The Twins are 33-11 (.750) when they’ve scored in the first inning since the 2023 season — 2nd best in MLB; League Avg: .614.

Guardians hitters are slugging just .358 against LHP since the 2022 season — lowest in MLB; League Avg: .408.

Guardians hitters had an OPS of just .662 (1,910 PA’s) against LHP in the 2023 season — lowest in MLB; League Avg: .742.

Guardians hitters have missed on just 22% of swings since the 2022 season — best in MLB; League Avg: 26%.

Guardians hitters have just 1,627 strikeouts in 9,019 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

The Twins batted just .150 with two-strikes in the 2023 season — lowest in MLB; League Avg: .172.

Twins hitters slugged .716 on the first pitch of at-bats in the 2023 season — 2nd best in MLB; League Avg: .596.

The Twins are batting just .149 with two-strikes since last season — lowest in MLB; League Avg: .172.

Twins hitters are slugging .699 on the first pitch of at-bats since last season — 2nd best in MLB; League Avg: .593.

Guardians pitchers have a strikeout rate of 35% with runners in scoring position this season — best in MLB; League Avg: 21%.

Opponents have a miss rate of 33% against Guardians pitchers this season — best in MLB; League Avg: 26%.

Guardians pitchers have a strikeout rate of 28% this season — 4th best in MLB; League Avg: 23%.

Opponents had a groundball rate of just 41% against Guardians pitchers in the 2023 season — 5th lowest in MLB; League Avg: 43%.

Twins pitchers have walked 461 of 6,245 batters (7%) since last season — 3rd best in MLB; League Avg: 9%.

Twins pitchers have walked 102 of 1,508 batters (7%) when facing the leadoff batter in the inning since last season — 4th best in MLB; League Avg: 8%.

Twins pitchers walked 443 of 6,028 batters (7%) in the 2023 season — tied for 3rd best in MLB; League Avg: 9%.

Opponents have a groundball rate of just 41% against Twins pitchers since the 2022 season — tied for 3rd lowest in MLB; League Avg: 43%.

Twins vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Zack Weiss (Minnesota Twins): Shoulder, 15-Day IL
  • Jhoan Duran (Minnesota Twins): Oblique, 15-Day IL
  • Anthony DeSclafani (Minnesota Twins): Elbow, 60-Day IL
  • Matt Canterino (Minnesota Twins): Shoulder, 7-Day IL
  • Trevor Larnach (Minnesota Twins): Toe, 7-Day IL
  • Royce Lewis (Minnesota Twins): Quadriceps, 10-Day IL
  • Max Kepler (Minnesota Twins): Leg, Day-To-Day
  • Jovani Moran (Minnesota Twins): Elbow, 60-Day IL
  • Josh Staumont (Minnesota Twins): Calf, 15-Day IL
  • Caleb Thielbar (Minnesota Twins): Hamstring, 15-Day IL
  • Justin Topa (Minnesota Twins): Kneecap, 15-Day IL
  • Jose De Leon (Minnesota Twins): Elbow, Out
  • Josh Winder (Minnesota Twins): Shoulder, 60-Day IL
  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.