Guardians vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, May 10

Chicago White Sox's watches the flight of the ball during a baseball game against the Los Angeles Angels Wednesday, May 31, 2023, in Chicago.
(AP Photo/Charles Rex Arbogast)
  • The Guardians are -115 favorites vs the White Sox
  • Guardians vs White Sox Over / Under today: 7.5 Runs
  • Guardians / White Sox TV Channel: BSGL | NSCH

The Cleveland Guardians (-115) visit Guaranteed Rate Field to take on the Chicago White Sox (-105) on Friday, May 10, 2024. First pitch is scheduled for 7:40pm EDT in Chicago, IL.

This season, the Guardians are 24-14 against the spread (ATS), while the White Sox are 18-20 ATS.

Guardians vs White Sox Starting Pitchers Today:

  • Guardians starting pitcher: Carlos Carrasco 2-2, 5.73 ERA
  • White Sox starting pitcher: Garrett Crochet 2-4, 5.32 ERA

Guardians vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-1.5 +150O 7.5 -120-115
White Sox +1.5 -185U 7.5 +100-105

Guardians vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Friday‘s MLB game with 53.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Josh Naylor has hit the Home Runs Over in 9 of his last 27 games (+25.50 Units / 94% ROI)
  • Jose Ramirez has hit the RBIs Over in 21 of his last 37 games (+13.40 Units / 36% ROI)
  • Will Brennan has hit the Singles Under in 16 of his last 21 games (+12.80 Units / 59% ROI)
  • Josh Naylor has hit the Hits Under in 11 of his last 14 away games (+11.65 Units / 50% ROI)
  • Andres Gimenez has hit the Runs Under in 17 of his last 23 games (+9.15 Units / 28% ROI)

And here are some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Andrew Benintendi has hit the Home Runs Over in 2 of his last 6 games at home (+13.00 Units / 217% ROI)
  • Andrew Vaughn has hit the Runs Under in his last 8 games (+8.00 Units / 50% ROI)
  • Gavin Sheets has hit the Singles Under in his last 7 games (+7.00 Units / 70% ROI)
  • Andrew Vaughn has hit the Total Bases Under in 13 of his last 17 games at home (+6.95 Units / 27% ROI)
  • Tommy Pham has hit the Hits Runs and RBIs Over in 9 of his last 11 games (+6.75 Units / 50% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 35 of their last 59 games (+8.60 Units / 13% ROI)
  • The Cleveland Guardians have covered the Run Line in 34 of their last 60 away games (+6.30 Units / 8% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 25 of their last 44 away games (+5.36 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 22 of their last 44 away games (+5.35 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 34 games (+4.72 Units / 12% ROI)
  • The Chicago White Sox have hit the Game Total Under in 70 of their last 124 games (+16.15 Units / 12% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 11 games (+5.24 Units / 45% ROI)
  • The Chicago White Sox have covered the Run Line in 14 of their last 24 games (+3.80 Units / 12% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 23-15 against the Run Line (+9.25 Units / 19.49% ROI).

  • 24-14 when betting on the Moneyline for +8.57 Units / 17.08% ROI
  • 20-16 when betting on the total runs Over for +2.5 Units / 6% ROI
  • 16-20 when betting on the total runs Under for -6.1 Units / -14.56% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 18-20 against the Run Line (-5.3 Units / -11.74% ROI).

  • 10-28 when betting on the Moneyline for -13.15 Units / -35.54% ROI
  • 17-19 when betting on the total runs Over for -4.1 Units / -9.99% ROI
  • 19-17 when betting on the total runs Under for +0.45 Units / 1.11% ROI

White Sox vs Guardians Home Run Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +350 0.5 -450
Eloy Jimenez (CWS) 0.5 +450 0.5 -650
Tommy Pham (CWS) 0.5 +475 0.5 -650
Andrew Vaughn (CWS) 0.5 +475 0.5 -700
David Fry (CLE) 0.5 +475 0.5 -700

White Sox vs Guardians Total Hits Prop Bets Today

Over Under
Tyler Freeman (CLE) 0.5 -250 0.5 +185
Eloy Jimenez (CWS) 0.5 -250 0.5 +185
Jose Ramirez (CLE) 0.5 -250 0.5 +190
Andrew Vaughn (CWS) 0.5 -250 0.5 +195
Josh Naylor (CLE) 0.5 -210 0.5 +155

White Sox vs Guardians RBI Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +145 0.5 -190
Eloy Jimenez (CWS) 0.5 +150 0.5 -200
Andrew Vaughn (CWS) 0.5 +155 0.5 -210
Josh Naylor (CLE) 0.5 +160 0.5 -225
Tommy Pham (CWS) 0.5 +175 0.5 -250

White Sox vs Guardians Strikeout Prop Bets Today

Over Under
Garrett Crochet (CWS) 5.5 -155 5.5 +120
Carlos Carrasco (CLE) 4.5 +115 4.5 -150

Carlos Carrasco has allowed an OBP of .399 (228 PA’s) when going through the lineup the second time in a game since last season — highest in MLB among starting pitchers with at least 78 total IP; League Avg: .312 — 0 Percentile.

Carlos Carrasco has allowed an OPS of 1.451 (222 PA’s) when he’s behind in the count since the 2022 season — 2nd highest in MLB among starting pitchers with at least 143 total IP; League Avg: 1.058 — first Percentile.

Opponents are hitting .475 (84-for-177) against Carlos Carrasco when he’s behind in the count since the 2022 season — highest in MLB among starting pitchers with at least 143 total IP; League Avg: .337 — first Percentile.

Carlos Carrasco has allowed a slugging percentage of .727 (104 Total Bases / 143 ABs) on inside fastballs since the 2022 season — highest in MLB among starting pitchers with at least 143 total IP; League Avg: .429 — 0 Percentile.

White Sox Starting Pitcher Stats & Trends

Garrett Crochet has thrown inside pitches 51% of the time (63/123) with runners in scoring position this season — highest among among AL Starters; League Avg: 32% — 100th Percentile.

Garrett Crochet has thrown inside pitches 47% of the time (99/213) with two-strikes this season — highest among among AL Starters; League Avg: 30% — 100th Percentile.

Garrett Crochet has thrown inside pitches 47% of the time (99/213) with two-strikes this season — highest among qualified SPs in MLB; League Avg: 30% — 100th Percentile.

Garrett Crochet has a strikeout rate of 36% (26 SO in 72 PAs) when going through the lineup the first time in a game this season — tied for 5th best among qualified SPs in MLB; League Avg: 25% — 95th Percentile.

Guardians Keys to the Game vs. the White Sox

The Guardians are 36-125 (.224) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .132.

The Guardians are just 10-17 (.370) when tied entering the 7th inning since the 2023 season — lowest in MLB; League Avg: .500.

The Guardians are 20-68 (.227) when trailing entering the 7th inning since the 2023 season — 3rd best in MLB; League Avg: .143.

The Guardians are 25-132 (.159) when trailing entering the 8th inning since the 2022 season — 2nd best in MLB; League Avg: .094.

White Sox Keys to the Game vs. the Guardians

The White Sox are just 23-47 (.329) after a win since the 2023 season — lowest in MLB; League Avg: .509.

The White Sox are just 56-13 (.812) when leading entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .898.

The White Sox are just 9-24 (.273) after a road win since the 2023 season — lowest in MLB; League Avg: .489.

The White Sox are just 6-13 (.316) after a win as favorites since the 2023 season — 2nd lowest in MLB; League Avg: .575.

Guardians hitters have just 1,788 strikeouts in 9,825 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters have just 2,552 strikeouts in 13,694 PA’s (19%) since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters had a Hard-Hit Rate of just 33% in the 2023 season — lowest in MLB; League Avg: 40%.

The Guardians are batting just .236 on the first pitch of at-bats this season — lowest in MLB; League Avg: .329.

White Sox hitters have an OPS of just .457 (3,868 PA’s) with two-strikes since last season — lowest in MLB; League Avg: .518.

White Sox hitters have an OBP of just .243 (243 PA’s) against LHP this season — lowest in MLB; League Avg: .315.

White Sox hitters have an OBP of just .291 (1,628 PA’s) against LHP since last season — lowest in MLB; League Avg: .322.

White Sox hitters have an OBP of just .288 (7,341 PA’s) since last season — lowest in MLB; League Avg: .319.

Opponents have a groundball rate of just 41% against Guardians pitchers since last season — 5th lowest in MLB; League Avg: 43%.

Guardians pitchers have walked 1 of 63 batters (2%) when facing the leadoff batter in the inning over the past seven days (7 games) — 2nd best in MLB; League Avg: 7%.

Opponents have a miss rate of 28% against Guardians pitchers this season — 3rd best in MLB; League Avg: 25%.

Guardians pitchers have a strikeout rate of 24% this season — 4th best in MLB; League Avg: 22%.

White Sox pitchers have thrown at least two strikes in their first three pitches to 59% of opposing batters this season — 3rd lowest in MLB; League Avg: 64%.

White Sox pitchers have a strikeout rate of just 21% this season — 4th lowest in MLB; League Avg: 22%.

The White Sox have won just 13% of games in which their opponents scored first this season — tied for lowest in MLB; League Avg: 33%.

White Sox pitchers have allowed opponents to score in three different innings in 58% of their games this season — highest in MLB; League Avg: 43%.

White Sox vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Eloy Jimenez (Chicago White Sox): Thigh, Day-To-Day
  • Yasmani Grandal (Chicago White Sox): Foot, 10-Day IL
  • Matt Foster (Chicago White Sox): Elbow, 60-Day IL
  • Jake Eder (Chicago White Sox): Shoulder, Day-To-Day
  • Jesse Scholtens (Chicago White Sox): Elbow, 60-Day IL
  • Shane Drohan (Chicago White Sox): Shoulder, 60-Day IL
  • Liam Hendriks (Chicago White Sox): Elbow, 60-Day IL
  • Jimmy Lambert (Chicago White Sox): Shoulder, 60-Day IL
  • Edgar Navarro (Chicago White Sox): Elbow, Out
  • Davis Martin (Chicago White Sox): Elbow, Out
  • Max Stassi (Chicago White Sox): Hip, 10-Day IL
  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.