Kansas City Royals vs San Diego Padres Prediction, Odds & Player Prop Bets Today – MLB, Jun 22

  • The Kansas City Royals are -115 favorites vs the San Diego Padres
  • Kansas City Royals vs San Diego Padres Over / Under today: 8.5 Runs
  • Kansas City Royals / San Diego Padres TV Channel: FDKC | PDTV

The Kansas City Royals (-115) visit Petco Park to take on the San Diego Padres (-105) on Sunday, June 22, 2025. First pitch is scheduled for 4:10pm EDT in San Diego, CA.

This season, the Kansas City Royals are 38-39 against the spread (ATS), while the San Diego Padres are 42-34 ATS.

Kansas City Royals vs San Diego Padres Starting Pitchers Today:

  • Kansas City Royals starting pitcher: , ERA
  • San Diego Padres starting pitcher: , ERA

Kansas City Royals vs. San Diego Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Kansas City Royals-1.5 +150O 8.5 -102-115
San Diego Padres +1.5 -180U 8.5 -118-105

Kansas City Royals vs San Diego Padres Prediction for Today’s Game

Based on recent trends the model predicts the will win Sunday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Kansas City Royals players for Sunday‘s game, looking at profitable historical betting trends:

Best Kansas City Royals Player Prop Bets Today:

  • Maikel Garcia has hit the Home Runs Over in 3 of his last 9 away games (+19.00 Units / 211% ROI)
  • Vinnie Pasquantino has hit the Total Bases Over in 17 of his last 25 away games (+10.10 Units / 33% ROI)
  • Jac Caglianone has hit the Runs Under in 13 of his last 15 games (+8.65 Units / 27% ROI)
  • Vinnie Pasquantino has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.25 Units / 28% ROI)
  • Kyle Isbel has hit the Singles Under in his last 8 games (+8.00 Units / 65% ROI)

And here are some favorite MLB player prop bets for San Diego Padres players for Sunday‘s game, looking at profitable historical betting trends:

Best San Diego Padres Player Prop Best Bets Today:

  • Luis Arraez has hit the Singles Over in 21 of his last 25 games at home (+13.25 Units / 27% ROI)
  • Fernando Tatis Jr. has hit the RBIs Under in 21 of his last 25 games (+11.50 Units / 19% ROI)
  • Gavin Sheets has hit the Total Bases Over in his last 10 games (+10.00 Units / 61% ROI)
  • Gavin Sheets has hit the Hits Over in his last 10 games (+10.00 Units / 61% ROI)
  • Xander Bogaerts has hit the Runs Over in 12 of his last 20 games at home (+9.80 Units / 49% ROI)
  • The Kansas City Royals have hit the Team Total Under in 53 of their last 77 games (+27.90 Units / 31% ROI)
  • The Kansas City Royals have covered the Run Line in 22 of their last 27 away games (+16.25 Units / 39% ROI)
  • The Kansas City Royals have hit the Game Total Under in 42 of their last 69 games (+13.40 Units / 18% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 46 of their last 76 games (+13.40 Units / 15% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 16 of their last 26 away games (+12.80 Units / 44% ROI)
  • The San Diego Padres have covered the Run Line in 20 of their last 33 games at home (+9.90 Units / 26% ROI)
  • The San Diego Padres have hit the Team Total Over in 23 of their last 35 games at home (+9.90 Units / 24% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 22 of their last 34 games (+9.35 Units / 23% ROI)
  • The San Diego Padres have hit the Game Total Under in 36 of their last 62 games (+8.40 Units / 12% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 21 of their last 33 games at home (+7.45 Units / 19% ROI)

Kansas City Royals Against the Spread (ATS) Record

Against the spread this season, the Kansas City Royals are 40-37 against the Run Line (-6.5 Units / -5.92% ROI).

  • 38-39 when betting on the Moneyline for -2.1 Units / -2.22% ROI
  • 31-45 when betting on the total runs Over for -17.77 Units / -21.16% ROI
  • 45-31 when betting on the total runs Under for +10.9 Units / 12.76% ROI

San Diego Padres Against the Spread (ATS) Record

Against the spread this season, the San Diego Padres are 42-34 against the Run Line (+3.75 Units / 3.75% ROI).

  • 41-35 when betting on the Moneyline for +1.05 Units / 1.04% ROI
  • 32-42 when betting on the total runs Over for -13.7 Units / -16.5% ROI
  • 42-32 when betting on the total runs Under for +6.55 Units / 7.77% ROI

San Diego Padres vs Kansas City Royals Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +325 0.5 -450
Bobby Witt Jr. (KC) 0.5 +333 0.5 -450
Manny Machado (SD) 0.5 +375 0.5 -500
Vinnie Pasquantino (KC) 0.5 +425 0.5 -600
Salvador Perez (KC) 0.5 +450 0.5 -625

San Diego Padres vs Kansas City Royals Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -275 0.5 +195
Maikel Garcia (KC) 0.5 -250 0.5 +185
Jonathan India (KC) 0.5 -225 0.5 +170
Xander Bogaerts (SD) 0.5 -220 0.5 +165
Vinnie Pasquantino (KC) 0.5 -220 0.5 +170

San Diego Padres vs Kansas City Royals RBI Prop Bets Today

Over Under
Vinnie Pasquantino (KC) 0.5 +130 0.5 -175
Bobby Witt Jr. (KC) 0.5 +145 0.5 -190
Manny Machado (SD) 0.5 +145 0.5 -200
Gavin Sheets (SD) 0.5 +160 0.5 -210
Salvador Perez (KC) 0.5 +170 0.5 -225

San Diego Padres vs Kansas City Royals Strikeout Prop Bets Today

Over Under
Randy Vasquez (SD) 2.5 -155 2.5 +120
Seth Lugo (KC) 4.5 +110 4.5 -140

starting pitcher – away

San Diego Padres Starting Pitcher Stats & Trends

starting pitcher – home

Kansas City Royals Keys to the Game vs. the San Diego Padres

keys to the game – away

San Diego Padres Keys to the Game vs. the Kansas City Royals

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.