Mariners vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 23

Houston Astros shortstop Jeremy Pena pops out during the first inning of a spring training baseball game against the New York Mets Thursday, Feb. 27, 2025, in Port St. Lucie, Fla.
(AP Photo/Jeff Roberson)
  • The Mariners are +105 favorites vs the Astros
  • Mariners vs Astros Over / Under today: 8.5 Runs
  • Mariners / Astros TV Channel: SCHN | RTNW

The Seattle Mariners (+105) visit Daikin Park to take on the Houston Astros (-125) on Friday, May 23, 2025. First pitch is scheduled for 8:10pm EDT in Houston, TX, TX.

This season, the Mariners are 28-21 against the spread (ATS), while the Astros are 27-23 ATS.

Mariners vs Astros Starting Pitchers Today:

  • Mariners starting pitcher: Emerson Hancock 1-2, 6.34 ERA
  • Astros starting pitcher: Ryan Gusto 3-2, 4.55 ERA

Mariners vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Mariners-1.5 +165O 8.5 -102+105
Astros +1.5 -200U 8.5 -118-125

Mariners vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Friday‘s MLB game with 51.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

  • Dylan Moore has hit the Runs Over in 17 of his last 25 away games (+15.95 Units / 61% ROI)
  • Rowdy Tellez has hit the Home Runs Over in 3 of his last 8 away games (+15.60 Units / 195% ROI)
  • J.P. Crawford has hit the Singles Over in 18 of his last 25 games (+12.35 Units / 44% ROI)
  • J.P. Crawford has hit the Hits Over in 20 of his last 25 away games (+11.75 Units / 28% ROI)
  • Dylan Moore has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.40 Units / 26% ROI)

And here are some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Isaac Paredes has hit the Home Runs Over in 5 of his last 10 games (+23.00 Units / 230% ROI)
  • Jeremy Pena has hit the Hits Over in 18 of his last 20 games at home (+18.05 Units / 45% ROI)
  • Isaac Paredes has hit the Total Bases Over in 20 of his last 25 games (+13.75 Units / 34% ROI)
  • Jeremy Pena has hit the Singles Over in 17 of his last 20 games at home (+13.45 Units / 52% ROI)
  • Isaac Paredes has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+11.65 Units / 74% ROI)
  • The Seattle Mariners have hit the Moneyline in 15 of their last 21 away games (+10.10 Units / 40% ROI)
  • The Seattle Mariners have hit the Game Total Over in 24 of their last 37 games (+9.60 Units / 24% ROI)
  • The Seattle Mariners have hit the Team Total Over in 27 of their last 43 games (+9.35 Units / 19% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 43 games (+7.95 Units / 16% ROI)
  • The Seattle Mariners have covered the Run Line in 21 of their last 37 games (+5.90 Units / 13% ROI)
  • The Houston Astros have covered the Run Line in 25 of their last 42 games (+10.42 Units / 19% ROI)
  • The Houston Astros have hit the Moneyline in 13 of their last 17 games at home (+8.20 Units / 37% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 11 games (+7.60 Units / 56% ROI)
  • The Houston Astros have hit the Team Total Under in 29 of their last 50 games (+6.45 Units / 11% ROI)
  • The Houston Astros have hit the Game Total Under in 11 of their last 17 games (+4.50 Units / 24% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 25-24 against the Run Line (+1.2 Units / 1.96% ROI).

  • 28-21 when betting on the Moneyline for +2.55 Units / 3.9% ROI
  • 27-20 when betting on the total runs Over for +4.9 Units / 9.14% ROI
  • 20-27 when betting on the total runs Under for -10.02 Units / -18.48% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 27-23 against the Run Line (+5.77 Units / 9.02% ROI).

  • 26-24 when betting on the Moneyline for -3.2 Units / -5.01% ROI
  • 21-27 when betting on the total runs Over for -8.6 Units / -15.71% ROI
  • 27-21 when betting on the total runs Under for +3.75 Units / 6.78% ROI

Astros vs Mariners Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +240 0.5 -300
Randy Arozarena (SEA) 0.5 +375 0.5 -525
Christian Walker (HOU) 0.5 +450 0.5 -650
Jorge Polanco (SEA) 0.5 +450 0.5 -650
Rowdy Tellez (SEA) 0.5 +525 0.5 -750

Astros vs Mariners Total Hits Prop Bets Today

Over Under
Jose Altuve (HOU) 0.5 -250 0.5 +180
Christian Walker (HOU) 0.5 -220 0.5 +165
Jake Meyers (HOU) 0.5 -210 0.5 +160
Isaac Paredes (HOU) 0.5 -190 0.5 +145
J.P. Crawford (SEA) 0.5 -185 0.5 +140

Astros vs Mariners RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +135 0.5 -175
Yainer Diaz (HOU) 0.5 +145 0.5 -190
Christian Walker (HOU) 0.5 +160 0.5 -210
Randy Arozarena (SEA) 0.5 +175 0.5 -235
Jose Altuve (HOU) 0.5 +185 0.5 -250

Astros vs Mariners Strikeout Prop Bets Today

Over Under
Emerson Hancock (SEA) 3.5 +110 3.5 -145
Ryan Gusto (HOU) 4.5 +120 4.5 -160

Emerson Hancock has spotted his fastball inside for a strike 82% (95/116) of the time this season — highest in MLB among starting pitchers with at least 19 total IP; League Avg: 65% — 100th Percentile.

Opponents have a groundball rate of just 32% (40/127) against Emerson Hancock in two-strike counts since last season — 3rd lowest in MLB among starting pitchers with at least 84 total IP; League Avg: 44% — second Percentile.

Left-handed hitters have a line drive rate of 33% (49/147) against Emerson Hancock since last season — highest in MLB among starting pitchers with at least 84 total IP; League Avg: 24% — 0 Percentile.

Opponents are hitting .464 (13-for-28) against Emerson Hancock on low fastballs this season — 7th highest in MLB among starting pitchers with at least 19 total IP; League Avg: .272 — sixth Percentile.

Astros Starting Pitcher Stats & Trends

Ryan Gusto has allowed a slugging percentage of just .111 (3 Total Bases / 27 ABs) on fastballs away this season — 5th best in MLB among starting pitchers with at least 19 total IP; League Avg: .372 — 96th Percentile.

Ryan Gusto has thrown fastballs up 64% of the time (194/304) this season — 4th highest in MLB among starting pitchers with at least 19 total IP; League Avg: 44% — 98th Percentile.

84% of Ryan Gusto’s fastball strikeouts are elevatedthis season — tied for 4th highest in MLB among starting pitchers with at least 19 total IP; League Avg: 51% — 96th Percentile.

Opponents have a miss rate of 28% (44/157) against Ryan Gusto on fastballs this season — 6th best in MLB among starting pitchers with at least 19 total IP; League Avg: 18% — 95th Percentile.

Mariners Keys to the Game vs. the Astros

The Mariners are 3-18 (.143) when trailing entering the 9th inning this season — best in MLB; League Avg: .041.

The Mariners are 20-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .908.

The Mariners were 58-5 (.921) when they scored 5 or more runs in the 2024 season — best in MLB; League Avg: .804.

The Mariners are 24-2 (.923) when they’ve had 5 or more XBH since last season — tied for 2nd best in MLB; League Avg: .809.

Astros Keys to the Game vs. the Mariners

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

The Astros are 17-7 (.708) after a loss this season — 2nd best in MLB; League Avg: .491.

The Astros are 97-72 (.574) after a loss since the 2023 season — 3rd best in MLB; League Avg: .494.

The Mariners are batting just .214 at home since last season — lowest in MLB; League Avg: .246.

The Mariners batted just .207 when facing the starting pitcher for the 3rd time in a game in the 2024 season — lowest in MLB; League Avg: .263.

The Mariners are batting just .226 when facing the starting pitcher for the 3rd time in a game since the 2023 season — lowest in MLB; League Avg: .264.

The Mariners are batting just .210 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .261.

Astros hitters have put 43% of balls in play to the left side of the field since the 2023 season — highest in MLB; League Avg: 38%.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters have put 46% of balls in play to the left side of the field this season — highest in MLB; League Avg: 38%.

Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.

Mariners pitchers allowed an OBP of just .251 (1,441 PA’s) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: .305.

Mariners pitchers walked 76 of 1,441 batters (5%) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: 7%.

Mariners pitchers have allowed an OBP of just .264 (1,885 PA’s) when facing the leadoff batter in the inning since last season — best in MLB; League Avg: .308.

Mariners pitchers allowed an OBP of just .276 (5,788 PA’s) in the 2024 season — best in MLB; League Avg: .312.

Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers since the 2023 season — 2nd best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Astros pitchers had an ERA of 3.62 (710.1 IP) on the road in 2023 — best in MLB; League Avg: 4.44.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.