Mariners vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 24

Houston Astros' Jose Altuve bats during the first inning of a spring training baseball game against the St. Louis Cardinals, Monday, March 6, 2023, in Jupiter, Fla. (AP Photo/Lynne Sladky)
(AP Photo/Lynne Sladky)
  • The Mariners are -105 favorites vs the Astros
  • Mariners vs Astros Over / Under today: 7.5 Runs
  • Mariners / Astros TV Channel: SCHN | RTNW

The Seattle Mariners (-105) visit Daikin Park to take on the Houston Astros (-115) on Saturday, May 24, 2025. First pitch is scheduled for 4:10pm EDT in Houston, TX, TX.

This season, the Mariners are 29-21 against the spread (ATS), while the Astros are 27-24 ATS.

Mariners vs Astros Starting Pitchers Today:

  • Mariners starting pitcher: Bryan Woo 5-1, 2.66 ERA
  • Astros starting pitcher: Framber Valdez 3-4, 3.61 ERA

Mariners vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Mariners-1.5 +155O 7.5 -125-105
Astros +1.5 -190U 7.5 +105-115

Mariners vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Saturday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Mariners vs Astros and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Mariners players for Saturday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

  • Dylan Moore has hit the Runs Over in 17 of his last 25 away games (+15.95 Units / 61% ROI)
  • J.P. Crawford has hit the Singles Over in 18 of his last 25 away games (+13.95 Units / 50% ROI)
  • Leody Taveras has hit the Home Runs Over in 2 of his last 4 games (+12.90 Units / 322% ROI)
  • Julio Rodriguez has hit the Hits Over in 17 of his last 25 games (+12.55 Units / 30% ROI)
  • Bryan Woo has hit the Pitching Outs Over in 8 of his last 9 games (+8.45 Units / 70% ROI)

And here are some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Isaac Paredes has hit the Home Runs Over in 5 of his last 10 games (+21.30 Units / 213% ROI)
  • Jeremy Pena has hit the Hits Over in 18 of his last 20 games at home (+19.15 Units / 49% ROI)
  • Isaac Paredes has hit the Total Bases Over in 20 of his last 25 games (+14.20 Units / 36% ROI)
  • Jeremy Pena has hit the Singles Over in 17 of his last 20 games at home (+13.05 Units / 50% ROI)
  • Isaac Paredes has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+11.65 Units / 74% ROI)
  • The Seattle Mariners have hit the Moneyline in 16 of their last 22 away games (+11.10 Units / 43% ROI)
  • The Seattle Mariners have hit the Team Total Over in 28 of their last 44 games (+10.45 Units / 21% ROI)
  • The Seattle Mariners have hit the Game Total Over in 24 of their last 38 games (+8.45 Units / 20% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 44 games (+6.95 Units / 13% ROI)
  • The Seattle Mariners have covered the Run Line in 22 of their last 38 games (+6.90 Units / 15% ROI)
  • The Houston Astros have covered the Run Line in 25 of their last 43 games (+9.42 Units / 17% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 21 games at home (+8.10 Units / 31% ROI)
  • The Houston Astros have hit the Team Total Under in 30 of their last 51 games (+7.45 Units / 13% ROI)
  • The Houston Astros have hit the Moneyline in 13 of their last 18 games at home (+7.00 Units / 30% ROI)
  • The Houston Astros have hit the Game Total Under in 12 of their last 18 games (+5.50 Units / 28% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 26-24 against the Run Line (+2.2 Units / 3.51% ROI).

  • 29-21 when betting on the Moneyline for +3.55 Units / 5.35% ROI
  • 27-21 when betting on the total runs Over for +3.75 Units / 6.85% ROI
  • 21-27 when betting on the total runs Under for -9.02 Units / -16.32% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 27-24 against the Run Line (+4.77 Units / 7.34% ROI).

  • 26-25 when betting on the Moneyline for -4.4 Units / -6.77% ROI
  • 21-28 when betting on the total runs Over for -9.75 Units / -17.44% ROI
  • 28-21 when betting on the total runs Under for +4.75 Units / 8.42% ROI

Astros vs Mariners Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +350 0.5 -450
Randy Arozarena (SEA) 0.5 +450 0.5 -625
Christian Walker (HOU) 0.5 +500 0.5 -700
Mitch Garver (SEA) 0.5 +550 0.5 -800
Julio Rodriguez (SEA) 0.5 +550 0.5 -800

Astros vs Mariners Total Hits Prop Bets Today

Over Under
Julio Rodriguez (SEA) 0.5 -250 0.5 +190
Jose Altuve (HOU) 0.5 -235 0.5 +175
Jeremy Pena (HOU) 0.5 -235 0.5 +180
Yainer Diaz (HOU) 0.5 -220 0.5 +165
Randy Arozarena (SEA) 0.5 -200 0.5 +150

Astros vs Mariners RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +165 0.5 -220
Randy Arozarena (SEA) 0.5 +170 0.5 -220
Christian Walker (HOU) 0.5 +185 0.5 -250
Dylan Moore (SEA) 0.5 +210 0.5 -295
Isaac Paredes (HOU) 0.5 +210 0.5 -285

Astros vs Mariners Strikeout Prop Bets Today

Over Under
Bryan Woo (SEA) 5.5 +110 5.5 -145
Framber Valdez (HOU) 6.5 +120 6.5 -155

Bryan Woo has not walked any of the 81 batters that they have faced when going through the lineup the second time in a game this season — best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Bryan Woo has a first-pitch in-zone of 67% (148/222) this season — 2nd best among qualified SPs in MLB; League Avg: 56% — 98th Percentile.

Opponents have a groundball rate of just 28% (16/58) against Bryan Woo in two-strike counts this season — 2nd lowest among qualified SPs in MLB; League Avg: 45% — second Percentile.

Bryan Woo has walked 1% of batters when going through the lineup the second time in a game since last season — best in MLB among starting pitchers with at least 84 total IP; League Avg: 7% — 100th Percentile.

Astros Starting Pitcher Stats & Trends

Opponents had a groundball rate of 61% (291/473) against Framber Valdez in the 2024 season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Opponents have a groundball rate of 60% (389/645) against Framber Valdez since last season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Framber Valdez located 42% of his pitches inside (302/710) with two-strikes in the 2024 season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

Framber Valdez located 41% of his pitches inside (1,071/2,598) in the 2024 season — highest among among AL Starters; League Avg: 29% — 100th Percentile.

Mariners Keys to the Game vs. the Astros

The Mariners are 91-17 (.843) when they’ve had 10 or more hits since the 2023 season — 2nd best in MLB; League Avg: .738.

The Mariners are 3-18 (.143) when trailing entering the 9th inning this season — best in MLB; League Avg: .041.

The Mariners are 173-3 (.983) when leading entering the 9th inning since the 2023 season — tied for best in MLB; League Avg: .950.

The Mariners are 24-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .958.

Astros Keys to the Game vs. the Mariners

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are 17-7 (.708) after a loss this season — 2nd best in MLB; League Avg: .493.

The Astros are just 1-79 (.012) when trailing entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .048.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

The Mariners batted just .207 when facing the starting pitcher for the 3rd time in a game in the 2024 season — lowest in MLB; League Avg: .263.

The Mariners are batting just .214 at home since last season — lowest in MLB; League Avg: .246.

Mariners hitters slugged just .219 with two-strikes in the 2024 season — lowest in MLB; League Avg: .264.

The Mariners are batting just .210 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .261.

The Astros are batting .338 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .256.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters have an OBP of .405 (247 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 2nd best in MLB; League Avg: .325.

Astros hitters have put 46% of balls in play to the left side of the field this season — highest in MLB; League Avg: 38%.

Mariners pitchers walked 76 of 1,441 batters (5%) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: 7%.

Mariners pitchers have walked 7% of batters since last season — best in MLB; League Avg: 8%.

Mariners pitchers walked 369 of 5,801 batters (6%) in the 2024 season — best in MLB; League Avg: 8%.

Mariners pitchers had an ERA of 2.83 (739.0 IP) at home in the 2024 season — best in MLB; League Avg: 3.98.

Opponents had a miss rate of 27% against Astros pitchers in the 2024 season — 2nd best in MLB; League Avg: 25%.

Astros pitchers have a strikeout rate of 25% since last season — 2nd best in MLB; League Avg: 22%.

Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 25%.

Astros pitchers had a strikeout rate of 45% with two-strikes in the 2024 season — 2nd best in MLB; League Avg: 42%.

More MLB Reading:


Bet now on Mariners vs Astros and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.