Mariners vs Padres Prediction, Odds & Player Prop Bets Today – MLB, May 16

San Diego Padres' Jake Cronenworth during a baseball game against the San Francisco Giants in San Francisco, Wednesday, June 21, 2023.
(AP Photo/Jeff Chiu)
  • The Padres are -155 favorites vs the Mariners
  • Mariners vs Padres Over / Under today: 8.5 Runs
  • Mariners / Padres TV Channel: ATV

The Seattle Mariners (+130) visit Petco Park to take on the San Diego Padres (-155) on Friday, May 16, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA, CA.

This season, the Mariners are 23-19 against the spread (ATS), while the Padres are 26-16 ATS.

Mariners vs Padres Starting Pitchers Today:

  • Mariners starting pitcher: Logan Evans 1-1, 6.61 ERA
  • Padres starting pitcher: Stephen Kolek 2-0, 0.00 ERA

Mariners vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Mariners+1.5 -165O 8.5 +100+130
Padres -1.5 +135U 8.5 -120-155

Mariners vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Friday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

  • Rowdy Tellez has hit the Singles Under in 22 of his last 25 games (+16.60 Units / 33% ROI)
  • Leonardo Rivas has hit the Runs Over in 8 of his last 10 games (+13.50 Units / 135% ROI)
  • Rowdy Tellez has hit the Home Runs Over in 3 of his last 7 away games (+13.00 Units / 186% ROI)
  • Julio Rodriguez has hit the Hits Over in 11 of his last 15 games (+9.70 Units / 38% ROI)
  • Leonardo Rivas has hit the Hits Runs and RBIs Over in 9 of his last 10 games (+8.25 Units / 60% ROI)

And here are some favorite MLB player prop bets for Padres players for Friday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Elias Diaz has hit the Home Runs Over in 3 of his last 10 games (+20.40 Units / 204% ROI)
  • Luis Arraez has hit the Total Bases Under in 21 of his last 25 games at home (+14.45 Units / 34% ROI)
  • Manny Machado has hit the Hits Runs and RBIs Over in 14 of his last 15 games (+13.30 Units / 71% ROI)
  • Manny Machado has hit the Runs Over in 12 of his last 15 games (+10.00 Units / 57% ROI)
  • Luis Arraez has hit the Singles Over in his last 10 games at home (+10.00 Units / 52% ROI)
  • The Seattle Mariners have hit the Game Total Over in 22 of their last 30 games (+13.15 Units / 40% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 23 of their last 36 games (+9.00 Units / 21% ROI)
  • The Seattle Mariners have hit the Moneyline in 10 of their last 14 away games (+6.70 Units / 43% ROI)
  • The Seattle Mariners have hit the Team Total Over in 22 of their last 36 games (+6.70 Units / 16% ROI)
  • The Seattle Mariners have covered the Run Line in 17 of their last 30 games (+5.00 Units / 13% ROI)
  • The San Diego Padres have covered the Run Line in 15 of their last 19 games at home (+13.10 Units / 59% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 15 of their last 19 games at home (+10.60 Units / 46% ROI)
  • The San Diego Padres have hit the Moneyline in 16 of their last 21 games at home (+9.20 Units / 29% ROI)
  • The San Diego Padres have hit the Team Total Over in 15 of their last 21 games at home (+8.70 Units / 35% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 14 of their last 18 games at home (+8.70 Units / 30% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 21-21 against the Run Line (+0.3 Units / 0.57% ROI).

  • 23-19 when betting on the Moneyline for -0.85 Units / -1.52% ROI
  • 25-15 when betting on the total runs Over for +8.45 Units / 18.42% ROI
  • 15-25 when betting on the total runs Under for -12.82 Units / -27.53% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 26-16 against the Run Line (+7.25 Units / 12.75% ROI).

  • 27-15 when betting on the Moneyline for +8.3 Units / 14.09% ROI
  • 19-22 when betting on the total runs Over for -4.65 Units / -10.26% ROI
  • 22-19 when betting on the total runs Under for +0.55 Units / 1.16% ROI

Padres vs Mariners Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +310 0.5 -400
Manny Machado (SD) 0.5 +375 0.5 -525
Jackson Merrill (SD) 0.5 +400 0.5 -550
Cal Raleigh (SEA) 0.5 +425 0.5 -600
Julio Rodriguez (SEA) 0.5 +500 0.5 -700

Padres vs Mariners Total Hits Prop Bets Today

Over Under
Xander Bogaerts (SD) 0.5 -225 0.5 +175
J.P. Crawford (SEA) 0.5 -220 0.5 +160
Leody Taveras (SEA) 0.5 -190 0.5 +145
Jake Cronenworth (SD) 0.5 -190 0.5 +145
Jorge Polanco (SEA) 0.5 -190 0.5 +145

Padres vs Mariners RBI Prop Bets Today

Over Under
Jackson Merrill (SD) 0.5 +110 0.5 -145
Manny Machado (SD) 0.5 +130 0.5 -165
Fernando Tatis Jr. (SD) 0.5 +140 0.5 -190
Xander Bogaerts (SD) 0.5 +150 0.5 -200
Cal Raleigh (SEA) 0.5 +150 0.5 -200

Padres vs Mariners Strikeout Prop Bets Today

Over Under
Stephen Kolek (SD) 4.5 +125 4.5 -165
Logan Evans (SEA) 3.5 +125 3.5 -165

Right-handed batters are hitting .385 (10-for-26) against Logan Evans this month (2 games) — tied for 2nd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .248 — second Percentile.

Opponents are hitting .458 (11-for-24) against Logan Evans on the road this month (1 game) — highest in MLB among starting pitchers with at least 4 total IP; League Avg: .245 — 0 Percentile.

Opponents are hitting .500 (8-for-16) against Logan Evans when going through the lineup the second time in a game this month (2 games) — 2nd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .251 — first Percentile.

Logan Evans has allowed an OBP of .448 (29 PA’s) against right-handed batters this month (2 games) — 5th highest in MLB among starting pitchers with at least 4 total IP; League Avg: .305 — fourth Percentile.

Padres Starting Pitcher Stats & Trends

Right-handed batters batted .327 (36-for-110) against Stephen Kolek in the 2024 season — highest among NL Relievers; League Avg: .233 — first Percentile.

Opponents batted .303 (59-for-195) against Stephen Kolek in the 2024 season — 4th highest among qualified RPs in MLB; League Avg: .231 — first Percentile.

Right-handed batters are hitting .316 (43-for-136) against Stephen Kolek since last season — highest among NL Relievers; League Avg: .233 — first Percentile.

Opponents had a two strike miss rate of just 18% (28/155) against Stephen Kolek in the 2024 season — 7th lowest among NL Relievers; League Avg: 26% — eighth Percentile.

Mariners Keys to the Game vs. the Padres

The Mariners are 3-16 (.158) when trailing entering the 9th inning this season — best in MLB; League Avg: .046.

The Mariners are 45-9 (.833) when they’ve had 10 or more hits since last season — 2nd best in MLB; League Avg: .748.

The Mariners are 10-8 (.556) on the road this season — 5th best in MLB; League Avg: .430.

The Mariners are 89-16 (.848) when they’ve had 10 or more hits since the 2023 season — best in MLB; League Avg: .738.

Padres Keys to the Game vs. the Mariners

The Padres are 4-10 (.286) when trailing entering the 7th inning this season — best in MLB; League Avg: .119.

The Padres are 3-12 (.200) when trailing entering the 8th inning this season — best in MLB; League Avg: .085.

The Padres are just 0-12 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .046.

The Padres were 48-33 (.593) on the road in the 2024 season — 2nd best in MLB; League Avg: .478.

The Mariners batted just .207 when facing the starting pitcher for the 3rd time in a game in the 2024 season — lowest in MLB; League Avg: .263.

The Mariners are batting just .210 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .262.

The Mariners are batting just .226 when facing the starting pitcher for the 3rd time in a game since the 2023 season — lowest in MLB; League Avg: .264.

Mariners hitters have an OBP of .359 (767 PA’s) on the road this season — best in MLB; League Avg: .309.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of it’s PA’s against LHP since last season — best in MLB; League Avg: 23%.

The Padres batted .275 on the road in the 2024 season — best in MLB; League Avg: .242.

Padres hitters have struck out in just 18% of it’s PA’s this season — best in MLB; League Avg: 22%.

Mariners pitchers walked 76 of 1,441 batters (5%) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: 7%.

Mariners pitchers walked 369 of 5,801 batters (6%) in the 2024 season — best in MLB; League Avg: 8%.

Mariners pitchers allowed an OBP of just .251 (1,441 PA’s) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: .305.

Mariners pitchers have allowed an OBP of just .263 (1,824 PA’s) when facing the leadoff batter in the inning since last season — best in MLB; League Avg: .308.

Opponents had a groundball batting average of just .196 against Padres pitchers with the shift in 2023 — best in MLB; League Avg: .240.

Opponents had a groundball rate of 45% against Padres pitchers in 2023 — 3rd highest in MLB; League Avg: 43%.

Padres pitchers have a strikeout rate of 46% with two-strikes this season — 4th best in MLB; League Avg: 42%.

Padres pitchers have an ERA of 3.52 (1661.0 IP) at home since the 2023 season — 2nd best in MLB; League Avg: 4.07.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.