Nationals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 16

Pittsburgh Pirates' Andrew McCutchen rounds third after hitting a solo home run off starting pitcher Freddy Peralta (51) during the fourth inning of a baseball game in Pittsburgh, Friday, June 30, 2023.
(AP Photo/Gene J. Puskar)
  • The Nationals are -110 favorites vs the Pirates
  • Nationals vs Pirates Over / Under today: 8 Runs
  • Nationals / Pirates TV Channel: MASN | SNPT

The Washington Nationals (-110) visit PNC Park to take on the Pittsburgh Pirates (-110) on Wednesday, April 16, 2025. First pitch is scheduled for 6:40pm EDT in Pittsburgh, PA.

This season, the Nationals are 7-10 against the spread (ATS), while the Pirates are 6-12 ATS.

Nationals vs Pirates Starting Pitchers Today:

  • Nationals starting pitcher: Mitchell Parker 2-0, 1.93 ERA
  • Pirates starting pitcher: Bailey Falter 0-2, 7.21 ERA

Nationals vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Nationals-1.5 +154O 8.5 -118-110
Pirates +1.5 -190U 8.5 -102-110

Nationals vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Nationals will win Wednesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Nationals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

  • James Wood has hit the Home Runs Over in 4 of his last 8 games (+22.00 Units / 275% ROI)
  • Keibert Ruiz has hit the Hits Over in 13 of his last 15 games (+9.85 Units / 33% ROI)
  • Mitchell Parker has hit the Walks Allowed Over in 9 of his last 10 away games (+8.40 Units / 75% ROI)
  • James Wood has hit the Runs Over in 8 of his last 10 games (+7.35 Units / 70% ROI)
  • Keibert Ruiz has hit the Hits Runs and RBIs Over in 8 of his last 9 games (+6.85 Units / 67% ROI)

And here are some favorite MLB player prop bets for Pirates players for Wednesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Bryan Reynolds has hit the Home Runs Over in 2 of his last 7 games at home (+14.00 Units / 200% ROI)
  • Ke’Bryan Hayes has hit the Runs Over in 6 of his last 8 games at home (+6.20 Units / 77% ROI)
  • Enmanuel Valdez has hit the Singles Under in 12 of his last 15 games (+5.80 Units / 18% ROI)
  • Tommy Pham has hit the Total Bases Under in 10 of his last 15 games (+5.75 Units / 29% ROI)
  • Enmanuel Valdez has hit the Hits Runs and RBIs Under in 13 of his last 20 games (+5.65 Units / 22% ROI)
  • The Washington Nationals have hit the Team Total Over in 9 of their last 11 games (+7.10 Units / 56% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 42 of their last 77 away games (+1.84 Units / 2% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 91 of their last 163 games (+7.80 Units / 4% ROI)
  • The Pittsburgh Pirates have hit the Game Total Over in 44 of their last 84 games at home (+2.95 Units / 3% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 45 of their last 84 games at home (+2.25 Units / 2% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 9-8 against the Run Line (-0.5 Units / -2.3% ROI).

  • 7-10 when betting on the Moneyline for -1.6 Units / -9.04% ROI
  • 11-6 when betting on the total runs Over for +4.5 Units / 23.87% ROI
  • 6-11 when betting on the total runs Under for -5.85 Units / -31.54% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 6-12 against the Run Line (-8.2 Units / -35.19% ROI).

  • 6-12 when betting on the Moneyline for -6.9 Units / -32.78% ROI
  • 8-9 when betting on the total runs Over for -1.95 Units / -9.75% ROI
  • 9-8 when betting on the total runs Under for +0.35 Units / 1.79% ROI

Pirates vs Nationals Home Run Prop Bets Today

Over Under
Andrew McCutchen (PIT) 0.5 +600 0.5 -1000
Bryan Reynolds (PIT) 0.5 +650 0.5 -1000
Josh Bell (WAS) 0.5 +675 0.5 -1100
Oneil Cruz (PIT) 0.5 +700 0.5 -1100
Alex Call (WAS) 0.5 +725 0.5 -1200

Pirates vs Nationals Total Hits Prop Bets Today

Over Under
Ke'Bryan Hayes (PIT) 0.5 -250 0.5 +190
James Wood (WAS) 0.5 -250 0.5 +180
Josh Bell (WAS) 0.5 -250 0.5 +185
Alex Call (WAS) 0.5 -235 0.5 +180
Luis Garcia (WAS) 0.5 -225 0.5 +175

Pirates vs Nationals RBI Prop Bets Today

Over Under
Josh Bell (WAS) 0.5 +150 0.5 -200
Alexander Canario (PIT) 0.5 +160 0.5 -210
Andrew McCutchen (PIT) 0.5 +165 0.5 -220
Amed Rosario (WAS) 0.5 +165 0.5 -220
Bryan Reynolds (PIT) 0.5 +175 0.5 -235

Pirates vs Nationals Strikeout Prop Bets Today

Over Under
Mitchell Parker (WAS) 4.5 -115 4.5 -115
Bailey Falter (PIT) 4.5 +145 4.5 -190

Mitchell Parker has a strikeout rate of just 27% (10 SO in 37 PAs) with two-strikes this season — 4th lowest among qualified SPs in MLB; League Avg: 44% — fifth Percentile.

Mitchell Parker has thrown elevated pitches 51% of the time (32/63) when behind in the count this season — highest among among NL Starters; League Avg: 28% — 100th Percentile.

4 of Mitchell Parker’s breaking pitch strikeouts are backdoor this season — tied for 2nd most among among NL Starters; League Avg: nan — 96th Percentile.

Mitchell Parker has walked 4 of 27 batters (15%) when going through the lineup the second time in a game this season — tied for 4th highest among qualified SPs in MLB; League Avg: 7% — fifth Percentile.

Pirates Starting Pitcher Stats & Trends

Bailey Falter walked 4 of 16 right-handed batters (25%) in his last start — tied for highest in MLB over the last week; League Avg: 8% — third Percentile.

Bailey Falter has walked 5 of 21 batters (24%) over the past seven days (1 games) — highest among NL Starters over the last week; League Avg: 9% — first Percentile.

Bailey Falter has a strike rate of just 41% (22/53) on sliders this season — lowest in MLB among starting pitchers with at least 6 total IP; League Avg: 63% — first Percentile.

Opponents have a swing rate of just 24% (13/53) against Bailey Falter on sliders this season — lowest in MLB among starting pitchers with at least 6 total IP; League Avg: 47% — first Percentile.

Nationals Keys to the Game vs. the Pirates

The Nationals were just 20-43 (.317) vs top 10 scoring offenses in the 2024 season They play the Dodgers (second best runs scored) today.

The Nationals are just 0-9 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Nationals are just 31-46 (.403) after a win since last season — tied for 5th lowest in MLB; League Avg: .495.

The Nationals are 7-1 (.875) when allowing 4 or fewer runs this season — 5th best in MLB; League Avg: .720.

Pirates Keys to the Game vs. the Nationals

The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.

The Pirates are just 7-49 (.125) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .246.

The Pirates were just 10-32 (.238) when their opponents score in the first inning in the 2024 season — 3rd lowest in MLB; League Avg: .359.

The Pirates were just 7-37 (.159) when allowing 2 or more home runs in the 2024 season — 3rd lowest in MLB; League Avg: .289.

Nationals hitters have an OPS of just .948 (2,332 PA’s) with the pitcher behind in the count since the 2023 season — lowest in MLB; League Avg: 1.083.

Nationals hitters averaged just 3.76 pitches per plate appearance against RHP in 2023 — 2nd lowest in MLB; League Avg: 3.90.

Nationals hitters put 39% of their swings in play on pitches 95 mph or greater in 2023 — highest in MLB; League Avg: 34%.

Nationals hitters had 298 extra-base hits out of 950 total hits (just 31%) against RHP in 2023 — 2nd lowest in MLB; League Avg: 36%.

The Pirates are batting just .074 on pitches out of the zone this season — lowest in MLB; League Avg: .145.

Pirates hitters are slugging just .295 against RHP this season — lowest in MLB; League Avg: .389.

Pirates hitters have an OBP of just .214 (56 PA’s) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB; League Avg: .325.

Pirates hitters have an OPS of just .654 (5,019 PA’s) against RHP since last season — 2nd lowest in MLB; League Avg: .711.

Nationals pitchers have a strikeout rate of just 20% since the 2023 season — tied for 2nd lowest in MLB; League Avg: 23%.

Nationals pitchers have a strikeout rate of just 39% with two-strikes since the 2023 season — 2nd lowest in MLB; League Avg: 42%.

Nationals pitchers allowed an OBP of .372 (1,428 PA’s) when facing the leadoff batter in the inning in 2023 — 2nd highest in MLB; League Avg: .316.

Nationals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Pirates pitchers have walked 11 of 166 batters (7%) when facing the leadoff batter in the inning this season — 4th best in MLB; League Avg: 9%.

Opponents have a miss rate of just 25% against Pirates pitchers since the 2023 season — tied for 5th lowest in MLB; League Avg: 26%.

The Pirates pitchers have allowed their opponents to score first in 55% of their games since the 2023 season — 4th highest in MLB; League Avg: 50%.

Pirates pitchers have a strikeout rate of just 17% with runners in scoring position this season — 5th lowest in MLB; League Avg: 21%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.