Orioles vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Jun 21

min read
Houston Astros Alex Bregman (2) and Houston Astros Yuli Gurriel celebrate after Game 2 of baseball's American League Championship Series between the Houston Astros and the New York Yankees, Thursday, Oct. 20, 2022, in Houston. The Houston Astros won 3-2.
(AP Photo/Eric Gay)
BetMGM Betting @BETMGM Jun 21, 2024, 11:01 AM
  • The Orioles are -155 favorites vs the Astros
  • Orioles vs Astros Over / Under today: 8.5 Runs
  • Orioles / Astros TV Channel: MASN | SCHN

The Baltimore Orioles (-165) visit Minute Maid Park to take on the Houston Astros (+140) on Friday, June 21, 2024. First pitch is scheduled for 8:10pm EDT in Houston, TX.

This season, the Orioles are 49-25 against the spread (ATS), while the Astros are 33-42 ATS.

Orioles vs Astros Starting Pitchers Today:

  • Orioles starting pitcher: Grayson Rodriguez 8-2, 3.22 ERA
  • Astros starting pitcher: Jake Bloss 0-0, 0.00 ERA

Orioles vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles-1.5 +100O 9 -120-165
Astros +1.5 -120U 9 +100+140

Orioles vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 60.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Anthony Santander has hit the Home Runs Over in 11 of his last 26 games (+27.10 Units / 104% ROI)
  • Gunnar Henderson has hit the Hits Over in 18 of his last 21 games (+16.25 Units / 39% ROI)
  • Gunnar Henderson has hit the Total Bases Over in 16 of his last 21 games (+12.50 Units / 55% ROI)
  • Anthony Santander has hit the Runs Over in 17 of his last 26 games (+12.15 Units / 46% ROI)
  • Anthony Santander has hit the RBIs Over in 12 of his last 19 games (+11.80 Units / 62% ROI)

And here are some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Alex Bregman has hit the Hits Over in 18 of his last 20 games (+17.20 Units / 43% ROI)
  • Jeremy Pena has hit the Total Bases Under in 21 of his last 24 games (+16.70 Units / 44% ROI)
  • Jeremy Pena has hit the Runs Under in 20 of his last 23 games (+15.20 Units / 41% ROI)
  • Jeremy Pena has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+14.10 Units / 53% ROI)
  • Alex Bregman has hit the Home Runs Over in 5 of his last 18 games at home (+13.50 Units / 75% ROI)
  • The Baltimore Orioles have covered the Run Line in 41 of their last 65 games (+23.45 Units / 30% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 40 of their last 59 games (+18.75 Units / 26% ROI)
  • The Baltimore Orioles have hit the Moneyline in 20 of their last 27 games (+12.20 Units / 32% ROI)
  • The Baltimore Orioles have hit the Team Total Over in 13 of their last 15 away games (+10.90 Units / 62% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 18 of their last 28 games (+9.55 Units / 23% ROI)
  • The Houston Astros have hit the Game Total Under in 38 of their last 58 games (+18.20 Units / 28% ROI)
  • The Houston Astros have hit the Team Total Under in 42 of their last 75 games (+6.90 Units / 8% ROI)
  • The Houston Astros have covered the Run Line in 12 of their last 23 games at home (+4.80 Units / 20% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 54 games (+4.80 Units / 8% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 5 of their last 8 games at home (+1.55 Units / 16% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 45-29 against the Run Line (+23.3 Units / 26.86% ROI).

  • 49-25 when betting on the Moneyline for +15.3 Units / 14.63% ROI
  • 37-26 when betting on the total runs Over for +8.8 Units / 11% ROI
  • 26-37 when betting on the total runs Under for -14.85 Units / -18.41% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 33-42 against the Run Line (-8.35 Units / -9.36% ROI).

  • 35-40 when betting on the Moneyline for -18 Units / -16.89% ROI
  • 26-46 when betting on the total runs Over for -24.05 Units / -29.37% ROI
  • 46-26 when betting on the total runs Under for +17.35 Units / 20.85% ROI

Astros vs Orioles Home Run Prop Bets Today

Over Under
Gunnar Henderson (BAL) 0.5 +333 0.5 -450
Yordan Alvarez (HOU) 0.5 +375 0.5 -500
Anthony Santander (BAL) 0.5 +375 0.5 -550
Ryan Mountcastle (BAL) 0.5 +475 0.5 -700
Ryan O'Hearn (BAL) 0.5 +500 0.5 -700

Astros vs Orioles Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -275 0.5 +210
Adley Rutschman (BAL) 0.5 -250 0.5 +185
Jeremy Pena (HOU) 0.5 -250 0.5 +190
Alex Bregman (HOU) 0.5 -250 0.5 +190
Yordan Alvarez (HOU) 0.5 -225 0.5 +170

Astros vs Orioles RBI Prop Bets Today

Over Under
Anthony Santander (BAL) 0.5 +135 0.5 -175
Ryan Mountcastle (BAL) 0.5 +140 0.5 -185
Ryan O'Hearn (BAL) 0.5 +140 0.5 -190
Gunnar Henderson (BAL) 0.5 +140 0.5 -190
Yordan Alvarez (HOU) 0.5 +150 0.5 -200

Astros vs Orioles Strikeout Prop Bets Today

Over Under
Grayson Rodriguez (BAL) 5.5 -120 5.5 -110

Opponents have a line drive rate of 43% (16/37) against Grayson Rodriguez with runners in scoring position this season — 2nd highest in MLB among starting pitchers with at least 28 total IP; League Avg: 24% — first Percentile.

Grayson Rodriguez has allowed an OBP of just .091 (44 PA’s) with two-strikes this month (3 games) — best among qualified SPs in MLB; League Avg: .247 — 100th Percentile.

Grayson Rodriguez has allowed an OBP of just .091 (44 PA’s) with two-strikes this month (3 games) — best among among AL Starters; League Avg: .244 — 100th Percentile.

Grayson Rodriguez has struck out just 10% (4/39) of right-handed batters he faced this month (3 games) — 2nd lowest among among AL Starters; League Avg: 22% — fourth Percentile.

Astros Starting Pitcher Stats & Trends

No Matchup notes for this Game

Orioles Keys to the Game vs. the Astros

The Orioles are 5-18 (.217) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .109.

The Orioles are 56-42 (.571) after a loss as underdogs since the 2022 season — 2nd best in MLB; League Avg: .413.

The Orioles are 18-7 (.720) when tied entering the 7th inning since the 2023 season — best in MLB; League Avg: .500.

The Orioles are 9-6 (.600) when their opponents score in the first inning this season — 2nd best in MLB; League Avg: .367.

Astros Keys to the Game vs. the Orioles

The Astros are just 0-30 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .059.

The Astros are 163-24 (.872) when scoring 5 or more runs since the 2022 season — best in MLB; League Avg: .794.

The Astros are 108-30 (.783) when they’ve hit 2 or more home runs since the 2022 season — 4th best in MLB; League Avg: .698.

The Astros are 41-34 (.547) vs top 10 scoring offenses since the 2022 season — 2nd best in MLB; League Avg: .420.

Orioles hitters have put just 35% of balls in play to the left side of the field since last season — 2nd lowest in MLB; League Avg: 39%.

Orioles hitters are slugging .285 on pitches out of the zone this season — best in MLB; League Avg: .211.

Orioles hitters are slugging .457 against RHP this season — best in MLB; League Avg: .391.

Orioles hitters have 102 extra-base hits out of 244 total hits (42%) with two-strikes this season — best in MLB; League Avg: 31%.

Astros hitters have just 781 strikeouts in 4,487 PA’s (17%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

14% of Astros’ hitters plate appearances have lasted only one pitch (2,097/15,134 PA’s) since the 2022 season — highest in MLB; League Avg: 11%.

Astros hitters have just 460 strikeouts in 2,637 PA’s (17%) against LHP since last season — best in MLB; League Avg: 22%.

The Astros have won 90% of road games in which they have scored three or more runs in an inning since the 2022 season — highest in MLB; League Avg: 74%.

In games when their opponents have scored three or more runs in an inning, the Orioles have have still managed to win 48% of the time this season — highest in MLB; League Avg: 24%.

The Orioles won 53% of road games in which their opponents scored first in the 2023 season — highest in MLB; League Avg: 29%.

Orioles pitchers have won 53% of games in which they have allowed their opponent to score in three different innings on the road this season — highest in MLB; League Avg: 24%.

The Orioles have won 50% of road games in which their opponents scored first since last season — highest in MLB; League Avg: 28%.

Opponents have a miss rate of 27% against Astros pitchers this season — 5th best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Opponents have a miss rate of 27% against Astros pitchers since last season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have an ERA of 3.53 (1739.0 IP) on the road since the 2022 season — best in MLB; League Avg: 4.25.

Astros vs. Orioles Injuries Tonight That May Affect Prop Bets 

  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL
  • Felix Bautista (Baltimore Orioles): Elbow, 60-Day IL
  • Terrin Vavra (Baltimore Orioles): Shoulder, Day-To-Day
  • John Means (Baltimore Orioles): Forearm, 15-Day IL
  • Kyle Bradish (Baltimore Orioles): Elbow, 15-Day IL
  • Cionel Perez (Baltimore Orioles): Oblique, 15-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.