- The Brewers are -125 favorites vs the Orioles
- Orioles vs Brewers Over / Under today: 8.5 Runs
- Orioles / Brewers TV Channel: MAS2 | FDWI | MLBN
The Baltimore Orioles (+105) visit American Family Field to take on the Milwaukee Brewers (-125) on Wednesday, May 21, 2025. First pitch is scheduled for 1:10pm EDT in Milwaukee, WI, WI.
This season, the Orioles are 15-32 against the spread (ATS), while the Brewers are 24-24 ATS.
Orioles vs Brewers Starting Pitchers Today:
- Orioles starting pitcher: Tomoyuki Sugano 4-3, 3.08 ERA
- Brewers starting pitcher: Chad Patrick 2-4, 3.40 ERA
Orioles vs. Brewers Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Orioles | -1.5 +170 | O 8 -102 | +105 |
| Brewers | +1.5 -210 | U 8 -118 | -125 |
Orioles vs Brewers Prediction for Today’s Game
Based on recent trends the model predicts the Brewers will win Wednesday‘s MLB game with 52.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:
Best Orioles Player Prop Bets Today:
- Gunnar Henderson has hit the Hits Runs and RBIs Under in 20 of his last 25 away games (+15.35 Units / 54% ROI)
- Cedric Mullins has hit the Home Runs Over in 3 of his last 7 games (+14.30 Units / 204% ROI)
- Gunnar Henderson has hit the Runs Under in 19 of his last 25 away games (+12.20 Units / 38% ROI)
- Gunnar Henderson has hit the Total Bases Under in 15 of his last 20 away games (+8.70 Units / 32% ROI)
- Jackson Holliday has hit the Singles Over in 17 of his last 25 games (+8.65 Units / 29% ROI)
And here are some favorite MLB player prop bets for Brewers players for Wednesday‘s game, looking at profitable historical betting trends:
Best Brewers Player Prop Best Bets Today:
- Sal Frelick has hit the Home Runs Over in 2 of his last 6 games (+19.00 Units / 317% ROI)
- Jackson Chourio has hit the Hits Under in 15 of his last 20 games (+13.25 Units / 41% ROI)
- Jackson Chourio has hit the Runs Under in 16 of his last 20 games (+11.10 Units / 40% ROI)
- William Contreras has hit the Total Bases Under in 19 of his last 25 games (+10.20 Units / 25% ROI)
- Christian Yelich has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+9.65 Units / 43% ROI)
Orioles Best Bets Today:
- The Baltimore Orioles have hit the Team Total Under in 30 of their last 42 games (+17.05 Units / 35% ROI)
- The Baltimore Orioles have hit the Game Total Under in 14 of their last 18 away games (+10.58 Units / 53% ROI)
- The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 16 away games (+7.99 Units / 40% ROI)
Brewers Best Bets Today:
- The Milwaukee Brewers have hit the Game Total Under in 28 of their last 45 games (+12.75 Units / 26% ROI)
- The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 22 of their last 45 games (+7.80 Units / 14% ROI)
- The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games (+6.60 Units / 12% ROI)
- The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 42 games (+6.42 Units / 12% ROI)
- The Milwaukee Brewers have hit the Moneyline in 15 of their last 23 games at home (+6.30 Units / 22% ROI)
Orioles Against the Spread (ATS) Record
Against the spread this season, the Orioles are 14-32 against the Run Line (-21.31 Units / -35.7% ROI).
- 15-32 when betting on the Moneyline for -24.5 Units / -42.26% ROI
- 22-22 when betting on the total runs Over for -1.83 Units / -3.56% ROI
- 22-22 when betting on the total runs Under for -2.27 Units / -4.35% ROI
Brewers Against the Spread (ATS) Record
Against the spread this season, the Brewers are 24-24 against the Run Line (-4.5 Units / -6.74% ROI).
- 24-25 when betting on the Moneyline for -2.35 Units / -3.98% ROI
- 17-29 when betting on the total runs Over for -15 Units / -27.7% ROI
- 29-17 when betting on the total runs Under for +10.4 Units / 19.35% ROI
Brewers vs Orioles Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Gunnar Henderson (BAL) | 0.5 +310 | 0.5 -400 |
| Rhys Hoskins (MIL) | 0.5 +340 | 0.5 -450 |
| Cedric Mullins (BAL) | 0.5 +375 | 0.5 -500 |
| Adley Rutschman (BAL) | 0.5 +375 | 0.5 -500 |
| Jackson Chourio (MIL) | 0.5 +425 | 0.5 -550 |
Brewers vs Orioles Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Christian Yelich (MIL) | 0.5 -250 | 0.5 +180 |
| Jackson Holliday (BAL) | 0.5 -235 | 0.5 +180 |
| Adley Rutschman (BAL) | 0.5 -235 | 0.5 +175 |
| Ryan Mountcastle (BAL) | 0.5 -210 | 0.5 +160 |
| Sal Frelick (MIL) | 0.5 -210 | 0.5 +155 |
Brewers vs Orioles RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Gunnar Henderson (BAL) | 0.5 +130 | 0.5 -175 |
| Rhys Hoskins (MIL) | 0.5 +140 | 0.5 -185 |
| Jackson Chourio (MIL) | 0.5 +145 | 0.5 -190 |
| Christian Yelich (MIL) | 0.5 +155 | 0.5 -210 |
| Adley Rutschman (BAL) | 0.5 +160 | 0.5 -210 |
Brewers vs Orioles Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Tomoyuki Sugano (BAL) | 3.5 -125 | 3.5 -105 |
| Chad Patrick (MIL) | 4.5 -110 | 4.5 -115 |
Orioles Starting Pitcher Stats & Trends
21% of Tomoyuki Sugano’s strikeouts are in the zone this season — lowest among qualified SPs in MLB; League Avg: 49% — first Percentile.
Tomoyuki Sugano has a strikeout rate of just 10% (8 SO in 81 PAs) when going through the lineup the second time in a game this season — tied for 2nd lowest among qualified SPs in MLB; League Avg: 22% — third Percentile.
Tomoyuki Sugano has a strikeout rate of just 14% (29 SO in 208 PAs) this season — 3rd lowest among qualified SPs in MLB; League Avg: 22% — third Percentile.
Tomoyuki Sugano has a in-zone of just 35% (73/211) in two strike counts this season — 2nd lowest among qualified SPs in MLB; League Avg: 43% — second Percentile.
Brewers Starting Pitcher Stats & Trends
71% of Chad Patrick’s strikeouts are in the zone this season — highest among qualified SPs in MLB; League Avg: 49% — 100th Percentile.
Left-handed hitters have a groundball rate of just 22% (14/63) against Chad Patrick this season — lowest among qualified SPs in MLB; League Avg: 43% — first Percentile.
Opponents have a groundball rate of just 27% (15/55) against Chad Patrick in two-strike counts this season — lowest among qualified SPs in MLB; League Avg: 45% — first Percentile.
Chad Patrick has thrown elevated pitches 45% of the time (90/202) on the first pitch of at-bats this season — highest among among NL Starters; League Avg: 30% — 100th Percentile.
Orioles Keys to the Game vs. the Brewers
The Orioles are just 2-13 (.133) after a win this season — 2nd lowest in MLB; League Avg: .504.
The Orioles are just 8-15 (.348) at home this season — tied for 2nd lowest in MLB; League Avg: .565.
The Orioles are just 12-19 (.387) after a loss this season — 3rd lowest in MLB; League Avg: .496.
The Orioles are just 4-28 (.125) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .292.
Brewers Keys to the Game vs. the Orioles
The Brewers are just 2-83 (.024) when trailing entering the 9th inning since last season — 5th lowest in MLB; League Avg: .049.
The Brewers were 93-69 (.574) in the 2024 season — tied for 4th best in MLB; League Avg: .500.
The Brewers are just 3-145 (.020) when trailing entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .049.
The Brewers are 29-17 (.630) when tied entering the 8th inning since the 2023 season — 2nd best in MLB; League Avg: .500.
Orioles Hitting Stats & Trends
Orioles hitters are slugging .751 with the pitcher behind in the count this season — best in MLB; League Avg: .572.
Orioles hitters are slugging just .144 on breaking pitches against LHP this season — lowest in MLB; League Avg: .334.
The Orioles have a winning percentage of just 35% at home this season — tied for 2nd lowest in MLB; League Avg: 57%.
Orioles hitters are slugging just .267 against LHP this season — lowest in MLB; League Avg: .375.
Brewers Hitting Stats & Trends
Brewers hitters had 129 extra-base hits out of 494 total hits (just 26%) with two-strikes in 2023 — lowest in MLB; League Avg: 33%.
Brewers hitters have a swing rate of just 45% since last season — 2nd lowest in MLB; League Avg: 48%.
Brewers hitters had a swing rate of just 45% in the 2024 season — 2nd lowest in MLB; League Avg: 48%.
Brewers hitters are slugging just .439 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .573.
Orioles Pitching Stats & Trends
Orioles pitchers have walked 13% of batters when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 8%.
Opponents have a miss rate of just 23% against Orioles pitchers this season — 3rd lowest in MLB; League Avg: 25%.
Orioles pitchers have an ERA of 6.32 (208.0 IP) at home this season — highest in MLB; League Avg: 3.84.
Orioles pitchers have allowed a slugging percentage of .485 this season — highest in MLB; League Avg: .395.
Brewers Pitching Stats & Trends
Batters facing the Brewers pitchers have struck out in the zone 55% of the time since last season — highest in MLB; League Avg: 50%. since last season — highest in MLB; League Avg: 50%.
Batters facing the Brewers pitchers have struck out in the zone 52% of the time since the 2023 season — highest in MLB; League Avg: 49%. since the 2023 season — highest in MLB; League Avg: 49%.
Opponents have a miss rate of just 24% against Brewers pitchers since last season — tied for 5th lowest in MLB; League Avg: 25%.
The Brewers have won just 11% of home games in which their opponents scored first this season — lowest in MLB; League Avg: 40%.
More MLB Reading:
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