Orioles vs Red Sox Prediction, Odds & Player Prop Bets Today – MLB, May 23

Boston Red Sox's Jarren Duran plays against the Toronto Blue Jays during the first inning of a baseball game, Saturday, Aug. 5, 2023, in Boston.
(AP Photo/Michael Dwyer)
  • The Red Sox are -140 favorites vs the Orioles
  • Orioles vs Red Sox Over / Under today: 9 Runs
  • Orioles / Red Sox TV Channel: MASN | NESN

The Baltimore Orioles (+105) visit Fenway Park to take on the Boston Red Sox (-125) on Friday, May 23, 2025. First pitch is scheduled for 1:35pm EDT in Boston, MA.

This season, the Orioles are 16-32 against the spread (ATS), while the Red Sox are 25-25 ATS.

Orioles vs Red Sox Starting Pitchers Today:

  • Orioles starting pitcher: Cade Povich 1-3, 5.27 ERA
  • Red Sox starting pitcher: Brayan Bello 2-1, 4.07 ERA

Orioles vs. Red Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles+1.5 -210O 9 +100+105
Red Sox -1.5 +160U 9 -120-125

Orioles vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Friday‘s MLB game with 53.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Gunnar Henderson has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+13.35 Units / 47% ROI)
  • Cedric Mullins has hit the Home Runs Over in 3 of his last 8 games (+13.30 Units / 166% ROI)
  • Gunnar Henderson has hit the Runs Under in 18 of his last 25 away games (+10.05 Units / 31% ROI)
  • Gunnar Henderson has hit the Total Bases Under in 18 of his last 25 away games (+8.95 Units / 26% ROI)
  • Ryan Mountcastle has hit the Hits Over in 8 of his last 9 away games (+8.85 Units / 54% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Friday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

  • Rob Refsnyder has hit the Home Runs Over in 3 of his last 6 games (+18.10 Units / 302% ROI)
  • Rafael Devers has hit the Walks Over in 15 of his last 20 games at home (+11.95 Units / 53% ROI)
  • Trevor Story has hit the Total Bases Under in 15 of his last 20 games (+11.20 Units / 41% ROI)
  • Carlos Narvaez has hit the Hits Over in 13 of his last 15 games (+10.35 Units / 51% ROI)
  • Carlos Narvaez has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+8.80 Units / 43% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 30 of their last 43 games (+15.70 Units / 31% ROI)
  • The Baltimore Orioles have hit the Game Total Under in 14 of their last 19 away games (+9.48 Units / 45% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 13 of their last 17 away games (+8.99 Units / 42% ROI)
  • The Baltimore Orioles have covered the Run Line in 3 of their last 6 away games (+0.94 Units / 13% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 22 of their last 33 games (+10.90 Units / 28% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 24 of their last 46 games (+9.90 Units / 15% ROI)
  • The Boston Red Sox have hit the Team Total Under in 26 of their last 41 games (+9.05 Units / 18% ROI)
  • The Boston Red Sox have hit the Game Total Under in 15 of their last 23 games at home (+6.25 Units / 25% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 24 games at home (+5.26 Units / 18% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 15-32 against the Run Line (-19.76 Units / -32.55% ROI).

  • 16-32 when betting on the Moneyline for -23.5 Units / -39.78% ROI
  • 23-22 when betting on the total runs Over for -0.83 Units / -1.58% ROI
  • 22-23 when betting on the total runs Under for -3.37 Units / -6.33% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 25-25 against the Run Line (+0.85 Units / 1.33% ROI).

  • 25-26 when betting on the Moneyline for -8.86 Units / -12.58% ROI
  • 24-26 when betting on the total runs Over for -4.37 Units / -7.76% ROI
  • 26-24 when betting on the total runs Under for +0.05 Units / 0.09% ROI

Red Sox vs Orioles Home Run Prop Bets Today

Over Under
Gunnar Henderson (BAL) 0.5 +450 0.5 -650
Alex Bregman (BOS) 0.5 +500 0.5 -700
Trevor Story (BOS) 0.5 +550 0.5 -800
Rob Refsnyder (BOS) 0.5 +575 0.5 -900
Ryan Mountcastle (BAL) 0.5 +600 0.5 -1000

Red Sox vs Orioles Total Hits Prop Bets Today

Over Under
Jarren Duran (BOS) 0.5 -275 0.5 +200
Alex Bregman (BOS) 0.5 -250 0.5 +185
Rafael Devers (BOS) 0.5 -210 0.5 +160
Ryan O'Hearn (BAL) 0.5 -210 0.5 +160
Ramon Urias (BAL) 0.5 -210 0.5 +155

Red Sox vs Orioles RBI Prop Bets Today

Over Under
Ryan Mountcastle (BAL) 0.5 +125 0.5 -165
Gunnar Henderson (BAL) 0.5 +135 0.5 -175
Alex Bregman (BOS) 0.5 +150 0.5 -200
Trevor Story (BOS) 0.5 +160 0.5 -210
Adley Rutschman (BAL) 0.5 +165 0.5 -220

Red Sox vs Orioles Strikeout Prop Bets Today

Over Under
Brayan Bello (BOS) 3.5 -165 3.5 +125
Cade Povich (BAL) 4.5 -155 4.5 +120

Opponents batted .347 (60-for-173) against Zach Eflin when going through the lineup the third time in a game in the 2024 season — 2nd highest among qualified SPs in MLB; League Avg: .258 — third Percentile.

Zach Eflin has allowed a slugging percentage of 1.000 (24 Total Bases / 24 ABs) over the past seven days (1 game) — highest among AL Starters over the last week; League Avg: .376 — second Percentile.

Zach Eflin has walked 2% of right-handed batters in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: 6% — 98th Percentile.

Zach Eflin has walked 2% of batters when going through the lineup the first time in a game since last season — best in MLB among starting pitchers with at least 84 total IP; League Avg: 8% — 100th Percentile.

Red Sox Starting Pitcher Stats & Trends

Brayan Bello has allowed an OBP of .425 (40 PA’s) with two-strikes this month (4 games) — highest among qualified SPs in MLB; League Avg: .231 — first Percentile.

Opponents have a Hard-Hit Rate of just 20% (8/40) against Brayan Bello in late innings since the 2023 season — best in MLB among starting pitchers with at least 148 total IP; League Avg: 39% — 100th Percentile.

Brayan Bello has allowed an OPS of .954 (40 PA’s) with two-strikes this month (4 games) — highest among qualified SPs in MLB; League Avg: .487 — first Percentile.

Brayan Bello has allowed an OBP of .425 (40 PA’s) with two-strikes this month (4 games) — highest among among AL Starters; League Avg: .231 — second Percentile.

Orioles Keys to the Game vs. the Red Sox

The Orioles are just 2-13 (.133) after a win this season — 2nd lowest in MLB; League Avg: .509.

The Orioles are just 8-15 (.348) at home this season — 3rd lowest in MLB; League Avg: .561.

The Orioles are just 4-28 (.125) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .292.

The Orioles are just 15-3 (.833) when leading entering the 8th inning this season — 4th lowest in MLB; League Avg: .908.

Red Sox Keys to the Game vs. the Orioles

The Red Sox are just 6-76 (.073) when trailing entering the 7th inning since last season — 3rd lowest in MLB; League Avg: .139.

The Red Sox are just 43-160 (.212) when scoring 4 or fewer runs since the 2023 season — tied for 3rd lowest in MLB; League Avg: .274.

The Red Sox were just 38-43 (.469) at home in the 2024 season — tied for 5th lowest in MLB; League Avg: .521.

The Red Sox were just 17-33 (.340) vs top 10 scoring offenses in the 2024 season They play the Blue Jays (23rd best runs scored) today.

Orioles hitters have an OPS of just .555 (490 PA’s) against LHP this season — lowest in MLB; League Avg: .685.

The Orioles are just 3-12 (.200) against the run line (-56.1% ROI) after a win this season — lowest in MLB; League Avg: .492.

The Orioles have a winning percentage of just 35% at home this season — 3rd lowest in MLB; League Avg: 56%.

Orioles hitters are slugging .758 with the pitcher behind in the count this season — best in MLB; League Avg: .571.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters have put just 32% of their swings in play against LHP this season — lowest in MLB; League Avg: 36%.

Red Sox hitters have put just 30% of their swings in play on the first pitch of at-bats this season — lowest in MLB; League Avg: 36%.

The Red Sox are batting .375 in hitter’s counts since last season — best in MLB; League Avg: .335.

Orioles pitchers have walked 13% of batters when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 8%.

Opponents have a miss rate of just 23% against Orioles pitchers this season — 3rd lowest in MLB; League Avg: 25%.

Orioles pitchers have an ERA of 6.32 (208.0 IP) at home this season — highest in MLB; League Avg: 3.86.

The Orioles have allowed 6.61 runs per game (152/23) at home this season — 3rd highest in MLB; League Avg: 4.28.

Red Sox pitchers walked 98 of 1,456 batters (7%) when facing the leadoff batter in the inning in the 2024 season — tied for 5th best in MLB; League Avg: 7%.

Opponents have a groundball rate of 45% against Red Sox pitchers this season — tied for 5th highest in MLB; League Avg: 43%.

Red Sox pitchers have walked 7% of batters when facing the leadoff batter in the inning since last season — 5th best in MLB; League Avg: 8%.

Opponents have a groundball rate of 44% against Red Sox pitchers since the 2023 season — 5th highest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.