Orioles vs Royals Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

Kansas City Royals' MJ Melendez bats during the first inning of a baseball game against the Los Angeles Angels Saturday, June 17, 2023, in Kansas City, Mo.
(AP Photo/Charlie Riedel)
  • The Royals are -125 favorites vs the Orioles
  • Orioles vs Royals Over / Under today: 9 Runs
  • Orioles / Royals TV Channel: MAS2 | BSKC

The Baltimore Orioles (+105) visit Ewing M. Kauffman Stadium to take on the Kansas City Royals (-125) on Sunday, April 21, 2024. First pitch is scheduled for 2:10pm EDT in Kansas City, MO.

This season, the Orioles are 13-7 against the spread (ATS), while the Royals are 13-8 ATS.

Orioles vs Royals Starting Pitchers Today:

  • Orioles starting pitcher: Cole Irvin 0-1, 6.76 ERA
  • Royals starting pitcher: Seth Lugo 3-0, 1.03 ERA

Orioles vs. Royals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles+1.5 -190O 9 -115+105
Royals -1.5 +155U 9 -105-125

Orioles vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Sunday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Orioles players for Sunday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Cedric Mullins has hit the Hits Runs and RBIs Over in 13 of his last 17 games (+9.90 Units / 53% ROI)
  • Cedric Mullins has hit the Hits Over in his last 9 games (+9.00 Units / 56% ROI)
  • Ryan O’Hearn has hit the Singles Over in 15 of his last 21 away games (+8.05 Units / 33% ROI)
  • Grayson Rodriguez has hit the Strikeouts Over in 8 of his last 9 away games (+7.45 Units / 70% ROI)
  • Cedric Mullins has hit the Total Bases Over in his last 7 games (+7.40 Units / 67% ROI)

And here are some favorite MLB player prop bets for Royals players for Sunday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

  • Seth Lugo has hit the Pitching Outs Over in 17 of his last 20 games (+13.85 Units / 54% ROI)
  • Seth Lugo has hit the Earned Runs Under in 16 of his last 20 games (+11.55 Units / 43% ROI)
  • Michael Wacha has hit the Strikeouts Over in his last 10 games at home (+10.50 Units / 86% ROI)
  • Michael Wacha has hit the Earned Runs Under in 17 of his last 23 games (+10.05 Units / 30% ROI)
  • Seth Lugo has hit the Strikeouts Under in 10 of his last 13 games at home (+7.15 Units / 42% ROI)
  • The Baltimore Orioles have hit the Moneyline in 90 of their last 147 games (+29.20 Units / 15% ROI)
  • The Baltimore Orioles have covered the Run Line in 50 of their last 71 away games (+24.15 Units / 24% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 46 of their last 69 away games (+19.47 Units / 24% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 34 of their last 69 away games (+14.61 Units / 18% ROI)
  • The Baltimore Orioles have hit the Game Total Under in 17 of their last 22 games (+11.60 Units / 48% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 23 of their last 39 games at home (+14.97 Units / 36% ROI)
  • The Kansas City Royals have covered the 1st Five Innings (F5) Run Line in 27 of their last 39 games at home (+14.10 Units / 31% ROI)
  • The Kansas City Royals have hit the Moneyline in 23 of their last 41 games at home (+12.70 Units / 30% ROI)
  • The Kansas City Royals have hit the Team Total Over in 21 of their last 30 games at home (+11.08 Units / 31% ROI)
  • The Kansas City Royals have covered the Run Line in 25 of their last 39 games at home (+10.90 Units / 24% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 12-8 against the Run Line (+6.8 Units / 31.41% ROI).

  • 13-7 when betting on the Moneyline for +3.6 Units / 12.63% ROI
  • 13-5 when betting on the total runs Over for +7.45 Units / 33.26% ROI
  • 5-13 when betting on the total runs Under for -9.3 Units / -42.86% ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 13-8 against the Run Line (+2.7 Units / 9.54% ROI).

  • 13-8 when betting on the Moneyline for +5.35 Units / 20.38% ROI
  • 8-12 when betting on the total runs Over for -5.6 Units / -23.53% ROI
  • 12-8 when betting on the total runs Under for +3.4 Units / 15.08% ROI

Royals vs Orioles Home Run Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +500 0.5 -750
Anthony Santander (BAL) 0.5 +500 0.5 -750
Gunnar Henderson (BAL) 0.5 +525 0.5 -750
Nelson Velazquez (KC) 0.5 +575 0.5 -900
Bobby Witt Jr. (KC) 0.5 +650 0.5 -1000

Royals vs Orioles Total Hits Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 -275 0.5 +195
Gunnar Henderson (BAL) 0.5 -250 0.5 +185
Adley Rutschman (BAL) 0.5 -250 0.5 +185
Vinnie Pasquantino (KC) 0.5 -225 0.5 +175
Hunter Renfroe (KC) 0.5 -200 0.5 +150

Royals vs Orioles RBI Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +130 0.5 -165
Bobby Witt Jr. (KC) 0.5 +140 0.5 -190
Vinnie Pasquantino (KC) 0.5 +160 0.5 -210
Anthony Santander (BAL) 0.5 +160 0.5 -210
Ryan Mountcastle (BAL) 0.5 +170 0.5 -225

Royals vs Orioles Strikeout Prop Bets Today

Over Under

Cole Irvin has a strike rate of 81% (52/64) with runners in scoring position this season — highest in MLB among starting pitchers with at least 7 total IP; League Avg: 64% — 100th Percentile.

Opponents have a Hard-Hit Rate of 67% (12/18) against Cole Irvin with two-strikes this season — highest in MLB among starting pitchers with at least 7 total IP; League Avg: 35% — 0 Percentile.

Opponents have a miss rate of just 18% (68/385) against Cole Irvin on the first pitch of at-bats since the 2022 season — 4th lowest in MLB among starting pitchers with at least 137 total IP; League Avg: 26% — second Percentile.

Cole Irvin has a strike rate of 71% (534/750) with runners in scoring position since the 2022 season — highest in MLB among starting pitchers with at least 137 total IP; League Avg: 64% — 100th Percentile.

Royals Starting Pitcher Stats & Trends

Seth Lugo has a strikeout rate of just 27% (13 SO in 49 PAs) with two-strikes this season — 3rd lowest among qualified SPs in MLB; League Avg: 43% — third Percentile.

Seth Lugo has a strikeout rate of just 6% (2 SO in 36 PAs) when going through the lineup the first time in a game this season — lowest among in AL; League Avg: 25% — second Percentile.

Seth Lugo has a strikeout rate of just 6% (2 SO in 36 PAs) when going through the lineup the first time in a game this season — tied for lowest among qualified SPs in MLB; League Avg: 26% — second Percentile.

Seth Lugo has a strikeout rate of just 13% (13 SO in 101 PAs) this season — 3rd lowest among in AL; League Avg: 23% — sixth Percentile.

Orioles Keys to the Game vs. the Royals

The Orioles are 17-6 (.739) when tied entering the 7th inning since the 2023 season — tied for best in MLB; League Avg: .500.

The Orioles are 85-13 (.867) when scoring 5 or more runs since the 2023 season — best in MLB; League Avg: .785.

The Orioles are 37-21 (.638) after a road win since the 2023 season — best in MLB; League Avg: .492.

The Orioles are 146-9 (.942) when leading entering the 7th inning since the 2022 season — best in MLB; League Avg: .868.

Royals Keys to the Game vs. the Orioles

The Royals are just 13-85 (.133) when their opponents score in the first inning since the 2022 season — lowest in MLB; League Avg: .362.

The Royals are just 18-13 (.581) when they’ve had 5 or more XBH since the 2023 season — 2nd lowest in MLB; League Avg: .791.

The Royals are just 11-15 (.423) after a loss as favorites since the 2022 season — lowest in MLB; League Avg: .589.

The Royals are just 17-44 (.279) after a road win since the 2022 season — lowest in MLB; League Avg: .492.

28% of Orioles hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB; League Avg: 21%.

Orioles hitters are slugging just .260 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB; League Avg: .412.

Orioles hitters are slugging .351 with two-strikes this season — best in MLB; League Avg: .249.

The Orioles are 207-135 (.602) against the run line (13.3% ROI) since the 2022 season — best in MLB; League Avg: .493.

Royals hitters have an OBP of just .280 (3,290 PA’s) on the road since last season — lowest in MLB; League Avg: .316.

The Royals have a winning percentage of just 30% on the road since the 2022 season — 2nd lowest in MLB; League Avg: 48%.

The Royals have won just 52% of games in which they have scored in at least three different innings on the road since the 2022 season — 2nd lowest in MLB; League Avg: 72%.

The Royals won only 28% of their road games in the 2023 season — 2nd lowest in MLB; League Avg: 48%.

Opponents have a line drive rate of just 19% against Orioles pitchers this season — lowest in MLB; League Avg: 23%.

The Orioles won 53% of road games in which their opponents scored first in the 2023 season — highest in MLB; League Avg: 29%.

Orioles pitchers have walked 48 of 753 batters (6%) this season — 2nd best in MLB; League Avg: 9%.

The Orioles won 49% of games in which their opponents scored first in the 2023 season — highest in MLB; League Avg: 34%.

The Royals won just 18% of games in which their opponents scored first in the 2023 season — lowest in MLB; League Avg: 34%.

Royals pitchers have won only 13% of games in which they have allowed their opponent to score in three different innings on the road since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a groundball batting average of .284 against Royals pitchers with runners on base since the 2022 season — tied for 2nd highest in MLB; League Avg: .254.

Royals pitchers have a strikeout rate of just 19% with runners in scoring position since last season — 3rd lowest in MLB; League Avg: 22%.

Royals vs. Orioles Injuries Tonight That May Affect Prop Bets 

  • Kyle Wright (Kansas City Royals): Shoulder, 60-Day IL
  • Austin Cox (Kansas City Royals): Knee, Day-To-Day
  • Michael Massey (Kansas City Royals): Back, 10-Day IL
  • Jake Brentz (Kansas City Royals): Hamstring, 15-Day IL
  • Josh Taylor (Kansas City Royals): Biceps, 15-Day IL
  • Carlos Hernandez (Kansas City Royals): Shoulder, 15-Day IL
  • Kris Bubic (Kansas City Royals): Elbow, 60-Day IL
  • Felix Bautista (Baltimore Orioles): Elbow, 60-Day IL
  • Terrin Vavra (Baltimore Orioles): Shoulder, Day-To-Day
  • John Means (Baltimore Orioles): Forearm, 15-Day IL
  • Kyle Bradish (Baltimore Orioles): Elbow, 15-Day IL
  • Cionel Perez (Baltimore Orioles): Oblique, 15-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.