Padres vs Brewers Prediction, Odds & Player Prop Bets Today – MLB, Jun 6

Milwaukee Brewers' William Contreras hits a two-run home run during the second inning of a baseball game against the San Francisco Giants Sunday, May 28, 2023, in Milwaukee. (AP Photo/Morry Gash)
(AP Photo/Morry Gash)
  • The Brewers are -150 favorites vs the Padres
  • Padres vs Brewers Over / Under today: 8.5 Runs
  • Padres / Brewers TV Channel: PDTV | FDWI

The San Diego Padres (+118) visit American Family Field to take on the Milwaukee Brewers (-145) on Friday, June 6, 2025. First pitch is scheduled for 8:10pm EDT in Milwaukee, WI, WI.

This season, the Padres are 35-26 against the spread (ATS), while the Brewers are 32-29 ATS.

Padres vs Brewers Starting Pitchers Today:

  • Padres starting pitcher: Randy Vasquez 3-4, 4.06 ERA
  • Brewers starting pitcher: Chad Patrick 3-4, 3.00 ERA

Padres vs. Brewers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres+1.5 -165O 8.5 -102+118
Brewers -1.5 +140U 8.5 -118-145

Padres vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Friday‘s MLB game with 57.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Friday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Gavin Sheets has hit the Home Runs Over in 3 of his last 7 away games (+17.80 Units / 254% ROI)
  • Fernando Tatis Jr. has hit the RBIs Under in 18 of his last 20 games (+13.50 Units / 31% ROI)
  • Jackson Merrill has hit the Hits Under in 17 of his last 20 games (+13.40 Units / 33% ROI)
  • Xander Bogaerts has hit the Runs Under in 14 of his last 15 away games (+12.95 Units / 47% ROI)
  • Fernando Tatis Jr. has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+12.05 Units / 50% ROI)

And here are some favorite MLB player prop bets for Brewers players for Friday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Best Bets Today:

  • Christian Yelich has hit the Walks Under in 20 of his last 25 games (+11.65 Units / 23% ROI)
  • Jackson Chourio has hit the Home Runs Over in 3 of his last 9 games (+11.50 Units / 128% ROI)
  • William Contreras has hit the Hits Under in 12 of his last 20 games (+10.80 Units / 46% ROI)
  • Joseph Ortiz has hit the Hits Runs and RBIs Under in 17 of his last 25 games at home (+10.70 Units / 34% ROI)
  • Joseph Ortiz has hit the Singles Under in 13 of his last 15 games at home (+9.90 Units / 42% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 19 games (+8.45 Units / 37% ROI)
  • The San Diego Padres have hit the Game Total Under in 28 of their last 47 games (+7.90 Units / 15% ROI)
  • The San Diego Padres have hit the Team Total Under in 18 of their last 27 away games (+7.80 Units / 25% ROI)
  • The San Diego Padres have hit the Moneyline in 8 of their last 13 games (+2.70 Units / 15% ROI)
  • The San Diego Padres have covered the Run Line in 3 of their last 5 games (+1.40 Units / 23% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 37 of their last 59 games (+12.30 Units / 17% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 29 of their last 59 games (+12.25 Units / 17% ROI)
  • The Milwaukee Brewers have hit the Game Total Under in 35 of their last 59 games (+12.10 Units / 19% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 13 of their last 17 games (+10.30 Units / 53% ROI)
  • The Milwaukee Brewers have hit the Team Total Over in 13 of their last 17 games (+8.85 Units / 45% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 32-29 against the Run Line (-0.15 Units / -0.19% ROI).

  • 35-26 when betting on the Moneyline for +2.65 Units / 3.13% ROI
  • 25-34 when betting on the total runs Over for -11.9 Units / -17.94% ROI
  • 34-25 when betting on the total runs Under for +6.05 Units / 8.89% ROI

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 32-29 against the Run Line (-2.8 Units / -3.22% ROI).

  • 34-29 when betting on the Moneyline for +4.95 Units / 6.64% ROI
  • 24-36 when betting on the total runs Over for -16.05 Units / -22.95% ROI
  • 36-24 when betting on the total runs Under for +9.75 Units / 14.18% ROI

Brewers vs Padres Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +333 0.5 -450
Jackson Merrill (SD) 0.5 +333 0.5 -450
Manny Machado (SD) 0.5 +340 0.5 -450
Jackson Chourio (MIL) 0.5 +450 0.5 -650
Christian Yelich (MIL) 0.5 +450 0.5 -650

Brewers vs Padres Total Hits Prop Bets Today

Over Under
Jackson Chourio (MIL) 0.5 -275 0.5 +195
Christian Yelich (MIL) 0.5 -250 0.5 +180
William Contreras (MIL) 0.5 -235 0.5 +175
Brice Turang (MIL) 0.5 -235 0.5 +180
Manny Machado (SD) 0.5 -225 0.5 +170

Brewers vs Padres RBI Prop Bets Today

Over Under
Jackson Merrill (SD) 0.5 +130 0.5 -175
Manny Machado (SD) 0.5 +145 0.5 -190
William Contreras (MIL) 0.5 +150 0.5 -200
Christian Yelich (MIL) 0.5 +155 0.5 -210
Rhys Hoskins (MIL) 0.5 +160 0.5 -210

Brewers vs Padres Strikeout Prop Bets Today

Over Under
Chad Patrick (MIL) 3.5 -160 3.5 +120
Randy Vasquez (SD) 3.5 +115 3.5 -155

Randy Vasquez has struck out just 10% (39/404) of left-handed batters he faced since the 2023 season — lowest in MLB among starting pitchers with at least 153 total IP; League Avg: 22% — 0 Percentile.

Randy Vasquez struck out just 8% (16/198) of left-handed batters he faced in the 2024 season — 2nd lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 22% — first Percentile.

Randy Vasquez has allowed an OBP of .409 (323 PA’s) vs left-handed batters since last season — highest in MLB among starting pitchers with at least 88 total IP; League Avg: .314 — 0 Percentile.

Left-handed batters are hitting .311 (110-for-354) against Randy Vasquez since the 2023 season — 2nd highest in MLB among starting pitchers with at least 153 total IP; League Avg: .246 — first Percentile.

Brewers Starting Pitcher Stats & Trends

Opponents have a groundball rate of just 26% (18/70) against Chad Patrick in two-strike counts this season — 2nd lowest among qualified SPs in MLB; League Avg: 45% — second Percentile.

Opponents have a groundball rate of just 26% (49/186) against Chad Patrick this season — lowest among qualified SPs in MLB; League Avg: 44% — first Percentile.

Left-handed hitters have a line drive rate of 36% (32/88) against Chad Patrick this season — highest among qualified SPs in MLB; League Avg: 24% — first Percentile.

Left-handed hitters have a groundball rate of just 22% (19/88) against Chad Patrick this season — lowest among qualified SPs in MLB; League Avg: 43% — first Percentile.

Padres Keys to the Game vs. the Brewers

The Padres are 7-17 (.292) when trailing entering the 7th inning this season — 2nd best in MLB; League Avg: .138.

The Padres are 19-9 (.679) at home this season — 4th best in MLB; League Avg: .552.

The Padres are 19-4 (.826) when they’ve had 10 or more hits this season — tied for 5th best in MLB; League Avg: .732.

The Padres were 48-33 (.593) on the road in the 2024 season — 2nd best in MLB; League Avg: .478.

Brewers Keys to the Game vs. the Padres

The Brewers are 53-5 (.914) when they’ve had 5 or more XBH since the 2023 season — best in MLB; League Avg: .799.

The Brewers are 217-168 (.564) since the 2023 season — 4th best in MLB; League Avg: .500.

The Brewers were 47-34 (.580) at home in the 2024 season — 5th best in MLB; League Avg: .521.

The Brewers were 26-21 (.553) vs the top 10 runs allowed teams in the 2024 season They play the Rockies (30th best runs allowed) today.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

The Padres batted .275 on the road in the 2024 season — best in MLB; League Avg: .242.

Padres hitters have a swing rate of 63% with two-strikes since last season — highest in MLB; League Avg: 60%.

Padres hitters have chased 43% of pitches out of the zone with two-strikes this season — highest in MLB; League Avg: 38%.

Brewers hitters came to the plate with runners in scoring position in 1,726 of their 6,170 plate appearances (28%) in the 2024 season — highest in MLB; League Avg: 25%.

Brewers hitters had 129 extra-base hits out of 494 total hits (just 26%) with two-strikes in 2023 — lowest in MLB; League Avg: 33%.

Brewers hitters have a swing rate of just 45% against RHP since last season — lowest in MLB; League Avg: 48%.

Brewers hitters have an OPS of just .642 (1,013 PA’s) at home this season — 2nd lowest in MLB; League Avg: .722.

The Padres pitchers have allowed an average Exit Velocity of just 88.3 MPH since the 2023 season (9,343 balls in play) — best in MLB; League Avg: 89.0

Padres pitchers have a strikeout rate of 46% with two-strikes this season — 4th best in MLB; League Avg: 42%.

Padres pitchers had a strikeout rate of 24% in the 2024 season — 5th best in MLB; League Avg: 23%.

Padres pitchers have a strikeout rate of 45% with two-strikes since last season — 4th best in MLB; League Avg: 42%.

Batters facing the Brewers pitchers have struck out on pitches in the zone 56% of the time since last season — highest in MLB; League Avg: 50%. since last season — highest in MLB; League Avg: 50%.

Batters facing the Brewers pitchers have struck out on pitches in the zone 58% of the time this season — highest in MLB; League Avg: 50%. this season — highest in MLB; League Avg: 50%.

Batters facing the Brewers pitchers have struck out on pitches in the zone 53% of the time since the 2023 season — highest in MLB; League Avg: 49%. since the 2023 season — highest in MLB; League Avg: 49%.

Brewers pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 5th highest in MLB; League Avg: 8%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.