Padres vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, May 6

Chicago Cubs' Nico Hoerner watches his RBI sacrifice fly during the fifth inning of a baseball game against the Colorado Rockies Saturday, Sept. 23, 2023, in Chicago. Chicago won 6-3. (AP Photo/Paul Beaty)
(AP Photo/Paul Beaty)
  • The Padres are -110 favorites vs the Cubs
  • Padres vs Cubs Over / Under today: 7 Runs
  • Padres / Cubs TV Channel: MARQ | PDTV

The San Diego Padres (-110) visit Wrigley Field to take on the Chicago Cubs (-110) on Monday, May 6, 2024. First pitch is scheduled for 7:40pm EDT in Chicago, IL.

This season, the Padres are 18-19 against the spread (ATS), while the Cubs are 23-12 ATS.

Padres vs Cubs Starting Pitchers Today:

  • Padres starting pitcher: Yu Darvish 1-1, 3.46 ERA
  • Cubs starting pitcher: Justin Steele 0-0, 1.93 ERA

Padres vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +155O 7 +100-110
Cubs +1.5 -190U 7 -120-110

Padres vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Monday‘s MLB game with 51.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Monday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Ha-Seong Kim has hit the Home Runs Over in 4 of his last 13 away games (+27.50 Units / 212% ROI)
  • Manny Machado has hit the Hits Over in 19 of his last 23 games (+14.00 Units / 30% ROI)
  • Manny Machado has hit the Singles Over in 18 of his last 23 games (+13.10 Units / 50% ROI)
  • Jackson Merrill has hit the RBIs Over in 8 of his last 9 away games (+11.25 Units / 125% ROI)
  • Jackson Merrill has hit the Runs Under in 15 of his last 18 games (+9.75 Units / 31% ROI)

And here are some favorite MLB player prop bets for Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Dansby Swanson has hit the Home Runs Over in 3 of his last 12 games at home (+16.00 Units / 133% ROI)
  • Nico Hoerner has hit the Hits Over in 10 of his last 11 games at home (+13.25 Units / 76% ROI)
  • Ian Happ has hit the Hits Runs and RBIs Under in 17 of his last 22 games (+11.40 Units / 43% ROI)
  • Nico Hoerner has hit the Total Bases Over in 9 of his last 11 games at home (+9.15 Units / 70% ROI)
  • Ian Happ has hit the Runs Under in 16 of his last 21 games (+8.90 Units / 28% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the Game Total Under in 68 of their last 129 games (+10.55 Units / 7% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)
  • The San Diego Padres have covered the Run Line in 17 of their last 27 games (+6.75 Units / 20% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 66 games (+9.21 Units / 12% ROI)
  • The Chicago Cubs have hit the Game Total Under in 21 of their last 32 games (+8.75 Units / 25% ROI)
  • The Chicago Cubs have hit the Moneyline in 23 of their last 34 games at home (+7.75 Units / 15% ROI)
  • The Chicago Cubs have hit the Team Total Over in 35 of their last 61 games at home (+6.79 Units / 10% ROI)
  • The Chicago Cubs have covered the Run Line in 19 of their last 34 games at home (+6.75 Units / 18% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 18-19 against the Run Line (+1.05 Units / 2.39% ROI).

  • 18-19 when betting on the Moneyline for -3.25 Units / -7.06% ROI
  • 20-16 when betting on the total runs Over for +2.7 Units / 6.68% ROI
  • 16-20 when betting on the total runs Under for -6 Units / -14.63% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 23-12 against the Run Line (+8.55 Units / 16.91% ROI).

  • 21-14 when betting on the Moneyline for +8.3 Units / 19.55% ROI
  • 15-20 when betting on the total runs Over for -7.05 Units / -18.22% ROI
  • 20-15 when betting on the total runs Under for +3.65 Units / 9.52% ROI

Cubs vs Padres Home Run Prop Bets Today

Over Under
Christopher Morel (CHC) 0.5 +450 0.5 -650
Patrick Wisdom (CHC) 0.5 +475 0.5 -700
Fernando Tatis Jr. (SD) 0.5 +550 0.5 -800
Manny Machado (SD) 0.5 +575 0.5 -900
Ian Happ (CHC) 0.5 +700 0.5 -1100

Cubs vs Padres Total Hits Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 -200 0.5 +150
Mike Tauchman (CHC) 0.5 -190 0.5 +140
Ian Happ (CHC) 0.5 -185 0.5 +140
Manny Machado (SD) 0.5 -185 0.5 +135
Christopher Morel (CHC) 0.5 -175 0.5 +130

Cubs vs Padres RBI Prop Bets Today

Over Under
Christopher Morel (CHC) 0.5 +155 0.5 -210
Manny Machado (SD) 0.5 +170 0.5 -225
Ian Happ (CHC) 0.5 +180 0.5 -250
Luis Arraez (MIA) 0.5 +200 0.5 -275
Patrick Wisdom (CHC) 0.5 +210 0.5 -300

Cubs vs Padres Strikeout Prop Bets Today

Over Under
Justin Steele (CHC) 4.5 +105 4.5 -140
Yu Darvish (SD) 5.5 +110 5.5 -145

Opponents are hitting .467 (7-for-15) against Yu Darvish’s elevated fastball this season — tied for highest in MLB among starting pitchers with at least 12 total IP; League Avg: .211 — first Percentile.

Yu Darvish has allowed a slugging percentage of .800 (12 Total Bases / 15 ABs) on elevated fastballs this season — 4th highest in MLB among starting pitchers with at least 12 total IP; League Avg: .359 — third Percentile.

Yu Darvish has thrown his slider 48% of the time (261/542) when he’s behind in the count since last season — highest in MLB among starting pitchers with at least 77 total SL; League Avg: 19% — 100th Percentile.

Yu Darvish has thrown breaking pitches 48% of the time (126/261) on pitches in the strike zone this season — 2nd highest in MLB among starting pitchers with at least 12 total IP; League Avg: 26% — 99th Percentile.

Cubs Starting Pitcher Stats & Trends

Justin Steele has thrown inside pitches 46% of the time (219/472) when behind in the count since last season — highest in MLB among starting pitchers with at least 77 total IP; League Avg: 31% — 100th Percentile.

Justin Steele has thrown inside pitches 43% of the time (1,415/3,286) in non-two strike counts since the 2022 season — highest in MLB among starting pitchers with at least 142 total IP; League Avg: 31% — 100th Percentile.

Justin Steele has thrown inside pitches 44% of the time (547/1,245) on the first pitch of at-bats since the 2022 season — highest in MLB among starting pitchers with at least 142 total IP; League Avg: 30% — 100th Percentile.

Justin Steele has walked 9 of 269 batters (3%) when going through the lineup the second time in a game since last season — 5th best in MLB among starting pitchers with at least 77 total IP; League Avg: 8% — 96th Percentile.

Padres Keys to the Game vs. the Cubs

The Padres are just 5-16 (.238) after a win as underdogs since the 2023 season — lowest in MLB; League Avg: .427.

The Padres are just 1-84 (.012) when trailing entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .053.

The Padres are just 7-135 (.049) when trailing entering the 8th inning since the 2022 season — tied for 2nd lowest in MLB; League Avg: .094.

The Padres are just 4-145 (.027) when trailing entering the 9th inning since the 2022 season — 5th lowest in MLB; League Avg: .050.

Cubs Keys to the Game vs. the Padres

The Cubs are 23-19 (.548) after a loss as underdogs since the 2023 season — 4th best in MLB; League Avg: .424.

The Cubs are just 37-39 (.487) after a loss as favorites since the 2022 season — 3rd lowest in MLB; League Avg: .587.

The Cubs are just 9-14 (.391) when tied entering the 7th inning since the 2023 season — 4th lowest in MLB; League Avg: .500.

Padres hitters have 38 extra-base hits out of 68 total hits (56%) with the pitcher behind in the count this season — best in MLB; League Avg: 39%.

Padres hitters have drawn 984 walks in 9,877 PA’s (10%) against RHP since the 2022 season — 2nd best in MLB; League Avg: 8%.

Padres hitters have an OPS of .760 (1,088 PA’s) against RHP this season — 3rd best in MLB; League Avg: .692.

The Padres are batting .196 with two-strikes this season — 2nd best in MLB; League Avg: .167.

Cubs hitters have an OPS of .841 (379 PA’s) in lefty-lefty matchups since last season — 2nd best in MLB; League Avg: .685.

Cubs hitters have an OPS of .788 (1,965 PA’s) against LHP since last season — 3rd best in MLB; League Avg: .735.

The Cubs are batting .268 against LHP since last season — 4th best in MLB; League Avg: .252.

Cubs hitters have an OPS of .800 (248 PA’s) against LHP this season — 3rd best in MLB; League Avg: .704.

The Padres pitchers allowed an average Exit Velocity of just 87.9 MPH in the 2023 season (3,921 balls in play) — best in MLB; League Avg: 89.0

Padres pitchers have walked 8 of 206 batters (4%) over the past seven days (6 games) — best in MLB; League Avg: 8%.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

The Padres pitchers have allowed an average Exit Velocity of just 88.2 MPH since last season (4,788 balls in play) — best in MLB; League Avg: 89.0

The Cubs pitchers have allowed their opponents to score first in just 27% of their games at home this season — lowest in MLB; League Avg: 57%.

The Cubs pitchers have allowed an average Exit Velocity of just 88.4 MPH since last season (4,914 balls in play) — 3rd best in MLB; League Avg: 89.0

The Cubs pitchers allowed an average Exit Velocity of just 88.3 MPH in the 2023 season (4,045 balls in play) — 2nd best in MLB; League Avg: 89.0

Opponents have a groundball rate of 45% against Cubs pitchers since last season — tied for 5th highest in MLB; League Avg: 43%.

Cubs vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Patrick Wisdom (Chicago Cubs): Back, 10-Day IL
  • Justin Steele (Chicago Cubs): Hamstring, 15-Day IL
  • Brennen Davis (Chicago Cubs): Undisclosed, Out
  • Tyler Duffey (Chicago Cubs): Back, Day-To-Day
  • Jameson Taillon (Chicago Cubs): Back, 15-Day IL
  • Caleb Kilian (Chicago Cubs): Shoulder, 60-Day IL
  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.

Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.