Padres vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, May 6

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Chicago Cubs' Nico Hoerner watches his RBI sacrifice fly during the fifth inning of a baseball game against the Colorado Rockies Saturday, Sept. 23, 2023, in Chicago. Chicago won 6-3. (AP Photo/Paul Beaty)
(AP Photo/Paul Beaty)
BetMGM Betting @BETMGM May 06, 2024, 11:42 AM
  • The Padres are -110 favorites vs the Cubs
  • Padres vs Cubs Over / Under today: 7 Runs
  • Padres / Cubs TV Channel: MARQ | PDTV

The San Diego Padres (-110) visit Wrigley Field to take on the Chicago Cubs (-110) on Monday, May 6, 2024. First pitch is scheduled for 7:40pm EDT in Chicago, IL.

This season, the Padres are 18-19 against the spread (ATS), while the Cubs are 23-12 ATS.

Padres vs Cubs Starting Pitchers Today:

  • Padres starting pitcher: Yu Darvish 1-1, 3.46 ERA
  • Cubs starting pitcher: Justin Steele 0-0, 1.93 ERA

Padres vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +155O 7 +100-110
Cubs +1.5 -190U 7 -120-110

Padres vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Monday‘s MLB game with 51.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Monday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Ha-Seong Kim has hit the Home Runs Over in 4 of his last 13 away games (+27.50 Units / 212% ROI)
  • Manny Machado has hit the Hits Over in 19 of his last 23 games (+14.00 Units / 30% ROI)
  • Manny Machado has hit the Singles Over in 18 of his last 23 games (+13.10 Units / 50% ROI)
  • Jackson Merrill has hit the RBIs Over in 8 of his last 9 away games (+11.25 Units / 125% ROI)
  • Jackson Merrill has hit the Runs Under in 15 of his last 18 games (+9.75 Units / 31% ROI)

And here are some favorite MLB player prop bets for Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Dansby Swanson has hit the Home Runs Over in 3 of his last 12 games at home (+16.00 Units / 133% ROI)
  • Nico Hoerner has hit the Hits Over in 10 of his last 11 games at home (+13.25 Units / 76% ROI)
  • Ian Happ has hit the Hits Runs and RBIs Under in 17 of his last 22 games (+11.40 Units / 43% ROI)
  • Nico Hoerner has hit the Total Bases Over in 9 of his last 11 games at home (+9.15 Units / 70% ROI)
  • Ian Happ has hit the Runs Under in 16 of his last 21 games (+8.90 Units / 28% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the Game Total Under in 68 of their last 129 games (+10.55 Units / 7% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)
  • The San Diego Padres have covered the Run Line in 17 of their last 27 games (+6.75 Units / 20% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 66 games (+9.21 Units / 12% ROI)
  • The Chicago Cubs have hit the Game Total Under in 21 of their last 32 games (+8.75 Units / 25% ROI)
  • The Chicago Cubs have hit the Moneyline in 23 of their last 34 games at home (+7.75 Units / 15% ROI)
  • The Chicago Cubs have hit the Team Total Over in 35 of their last 61 games at home (+6.79 Units / 10% ROI)
  • The Chicago Cubs have covered the Run Line in 19 of their last 34 games at home (+6.75 Units / 18% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 18-19 against the Run Line (+1.05 Units / 2.39% ROI).

  • 18-19 when betting on the Moneyline for -3.25 Units / -7.06% ROI
  • 20-16 when betting on the total runs Over for +2.7 Units / 6.68% ROI
  • 16-20 when betting on the total runs Under for -6 Units / -14.63% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 23-12 against the Run Line (+8.55 Units / 16.91% ROI).

  • 21-14 when betting on the Moneyline for +8.3 Units / 19.55% ROI
  • 15-20 when betting on the total runs Over for -7.05 Units / -18.22% ROI
  • 20-15 when betting on the total runs Under for +3.65 Units / 9.52% ROI

Cubs vs Padres Home Run Prop Bets Today

Over Under
Christopher Morel (CHC) 0.5 +450 0.5 -650
Patrick Wisdom (CHC) 0.5 +475 0.5 -700
Fernando Tatis Jr. (SD) 0.5 +550 0.5 -800
Manny Machado (SD) 0.5 +575 0.5 -900
Ian Happ (CHC) 0.5 +700 0.5 -1100

Cubs vs Padres Total Hits Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 -200 0.5 +150
Mike Tauchman (CHC) 0.5 -190 0.5 +140
Ian Happ (CHC) 0.5 -185 0.5 +140
Manny Machado (SD) 0.5 -185 0.5 +135
Christopher Morel (CHC) 0.5 -175 0.5 +130

Cubs vs Padres RBI Prop Bets Today

Over Under
Christopher Morel (CHC) 0.5 +155 0.5 -210
Manny Machado (SD) 0.5 +170 0.5 -225
Ian Happ (CHC) 0.5 +180 0.5 -250
Luis Arraez (MIA) 0.5 +200 0.5 -275
Patrick Wisdom (CHC) 0.5 +210 0.5 -300

Cubs vs Padres Strikeout Prop Bets Today

Over Under
Justin Steele (CHC) 4.5 +105 4.5 -140
Yu Darvish (SD) 5.5 +110 5.5 -145

Opponents are hitting .467 (7-for-15) against Yu Darvish’s elevated fastball this season — tied for highest in MLB among starting pitchers with at least 12 total IP; League Avg: .211 — first Percentile.

Yu Darvish has allowed a slugging percentage of .800 (12 Total Bases / 15 ABs) on elevated fastballs this season — 4th highest in MLB among starting pitchers with at least 12 total IP; League Avg: .359 — third Percentile.

Yu Darvish has thrown his slider 48% of the time (261/542) when he’s behind in the count since last season — highest in MLB among starting pitchers with at least 77 total SL; League Avg: 19% — 100th Percentile.

Yu Darvish has thrown breaking pitches 48% of the time (126/261) on pitches in the strike zone this season — 2nd highest in MLB among starting pitchers with at least 12 total IP; League Avg: 26% — 99th Percentile.

Cubs Starting Pitcher Stats & Trends

Justin Steele has thrown inside pitches 46% of the time (219/472) when behind in the count since last season — highest in MLB among starting pitchers with at least 77 total IP; League Avg: 31% — 100th Percentile.

Justin Steele has thrown inside pitches 43% of the time (1,415/3,286) in non-two strike counts since the 2022 season — highest in MLB among starting pitchers with at least 142 total IP; League Avg: 31% — 100th Percentile.

Justin Steele has thrown inside pitches 44% of the time (547/1,245) on the first pitch of at-bats since the 2022 season — highest in MLB among starting pitchers with at least 142 total IP; League Avg: 30% — 100th Percentile.

Justin Steele has walked 9 of 269 batters (3%) when going through the lineup the second time in a game since last season — 5th best in MLB among starting pitchers with at least 77 total IP; League Avg: 8% — 96th Percentile.

Padres Keys to the Game vs. the Cubs

The Padres are just 5-16 (.238) after a win as underdogs since the 2023 season — lowest in MLB; League Avg: .427.

The Padres are just 1-84 (.012) when trailing entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .053.

The Padres are just 7-135 (.049) when trailing entering the 8th inning since the 2022 season — tied for 2nd lowest in MLB; League Avg: .094.

The Padres are just 4-145 (.027) when trailing entering the 9th inning since the 2022 season — 5th lowest in MLB; League Avg: .050.

Cubs Keys to the Game vs. the Padres

The Cubs are 23-19 (.548) after a loss as underdogs since the 2023 season — 4th best in MLB; League Avg: .424.

The Cubs are just 37-39 (.487) after a loss as favorites since the 2022 season — 3rd lowest in MLB; League Avg: .587.

The Cubs are just 9-14 (.391) when tied entering the 7th inning since the 2023 season — 4th lowest in MLB; League Avg: .500.

Padres hitters have 38 extra-base hits out of 68 total hits (56%) with the pitcher behind in the count this season — best in MLB; League Avg: 39%.

Padres hitters have drawn 984 walks in 9,877 PA’s (10%) against RHP since the 2022 season — 2nd best in MLB; League Avg: 8%.

Padres hitters have an OPS of .760 (1,088 PA’s) against RHP this season — 3rd best in MLB; League Avg: .692.

The Padres are batting .196 with two-strikes this season — 2nd best in MLB; League Avg: .167.

Cubs hitters have an OPS of .841 (379 PA’s) in lefty-lefty matchups since last season — 2nd best in MLB; League Avg: .685.

Cubs hitters have an OPS of .788 (1,965 PA’s) against LHP since last season — 3rd best in MLB; League Avg: .735.

The Cubs are batting .268 against LHP since last season — 4th best in MLB; League Avg: .252.

Cubs hitters have an OPS of .800 (248 PA’s) against LHP this season — 3rd best in MLB; League Avg: .704.

The Padres pitchers allowed an average Exit Velocity of just 87.9 MPH in the 2023 season (3,921 balls in play) — best in MLB; League Avg: 89.0

Padres pitchers have walked 8 of 206 batters (4%) over the past seven days (6 games) — best in MLB; League Avg: 8%.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

The Padres pitchers have allowed an average Exit Velocity of just 88.2 MPH since last season (4,788 balls in play) — best in MLB; League Avg: 89.0

The Cubs pitchers have allowed their opponents to score first in just 27% of their games at home this season — lowest in MLB; League Avg: 57%.

The Cubs pitchers have allowed an average Exit Velocity of just 88.4 MPH since last season (4,914 balls in play) — 3rd best in MLB; League Avg: 89.0

The Cubs pitchers allowed an average Exit Velocity of just 88.3 MPH in the 2023 season (4,045 balls in play) — 2nd best in MLB; League Avg: 89.0

Opponents have a groundball rate of 45% against Cubs pitchers since last season — tied for 5th highest in MLB; League Avg: 43%.

Cubs vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Patrick Wisdom (Chicago Cubs): Back, 10-Day IL
  • Justin Steele (Chicago Cubs): Hamstring, 15-Day IL
  • Brennen Davis (Chicago Cubs): Undisclosed, Out
  • Tyler Duffey (Chicago Cubs): Back, Day-To-Day
  • Jameson Taillon (Chicago Cubs): Back, 15-Day IL
  • Caleb Kilian (Chicago Cubs): Shoulder, 60-Day IL
  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.