Padres vs Giants Prediction, Odds & Player Prop Bets Today – MLB, Apr 6

San Francisco Giants' Thairo Estrada rounds first after hitting a solo home run against the Los Angeles Dodgers during the sixth inning of a baseball game in Los Angeles, Friday, Sept. 22, 2023. (AP Photo/Alex Gallardo)
(AP Photo/Alex Gallardo)
  • The Padres are -110 favorites vs the Giants
  • Padres vs Giants Over / Under today: 8 Runs
  • Padres / Giants TV Channel: NSBA | MLBN | PDTV

The San Diego Padres (-110) visit Oracle Park to take on the San Francisco Giants (-110) on Saturday, April 6, 2024. First pitch is scheduled for 9:05pm EDT in San Francisco, CA.

This season, the Padres are 4-6 against the spread (ATS), while the Giants are 4-4 ATS.

Padres vs Giants Starting Pitchers Today:

  • Padres starting pitcher: Michael King 1-0, 6.14 ERA
  • Giants starting pitcher: Keaton Winn 0-1, 5.41 ERA

Padres vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +155O 8 -110-110
Giants +1.5 -190U 8 -110-110

Padres vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Saturday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Saturday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Jake Cronenworth has hit the Total Bases Over in 29 of his last 41 games (+18.40 Units / 32% ROI)
  • Xander Bogaerts has hit the Hits Runs and RBIs Over in 27 of his last 36 games (+16.20 Units / 35% ROI)
  • Blake Snell has hit the Earned Runs Under in 21 of his last 26 games (+15.80 Units / 46% ROI)
  • Xander Bogaerts has hit the Total Bases Over in 24 of his last 36 games (+15.30 Units / 33% ROI)
  • Blake Snell has hit the Pitching Outs Over in 20 of his last 27 games (+12.35 Units / 38% ROI)

And here are some favorite MLB player prop bets for Giants players for Saturday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • Logan Webb has hit the Pitching Outs Over in 24 of his last 33 games (+14.90 Units / 35% ROI)
  • Nick Ahmed has hit the Hits Runs and RBIs Under in his last 12 games at home (+12.35 Units / 66% ROI)
  • Austin Slater has hit the Singles Under in 20 of his last 28 games (+10.00 Units / 27% ROI)
  • Matt Chapman has hit the Total Bases Under in 18 of his last 25 games at home (+9.90 Units / 27% ROI)
  • Nick Ahmed has hit the Hits Under in 10 of his last 12 games at home (+9.60 Units / 79% ROI)
  • The San Diego Padres have hit the Game Total Under in 84 of their last 155 games (+17.70 Units / 10% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have hit the Team Total Under in 44 of their last 77 away games (+7.65 Units / 8% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 73 of their last 115 games (+27.02 Units / 20% ROI)
  • The San Francisco Giants have hit the Team Total Under in 55 of their last 85 games (+22.17 Units / 22% ROI)
  • The San Francisco Giants have hit the Game Total Under in 86 of their last 148 games (+22.10 Units / 14% ROI)
  • The San Francisco Giants have hit the Moneyline in 28 of their last 47 games at home (+5.40 Units / 8% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in their last 2 games (+2.05 Units / 100% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 4-6 against the Run Line (-1.03 Units / -9.2% ROI).

  • 4-6 when betting on the Moneyline for -2.81 Units / -22.04% ROI
  • 5-4 when betting on the total runs Over for +0.62 Units / 5.55% ROI
  • 4-5 when betting on the total runs Under for -1.5 Units / -13.67% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 4-4 against the Run Line (-1.8 Units / -14.94% ROI).

  • 3-5 when betting on the Moneyline for -1.85 Units / -22.16% ROI
  • 7-1 when betting on the total runs Over for +5.9 Units / 67.05% ROI
  • 1-7 when betting on the total runs Under for -6.8 Units / -76.84% ROI

Giants vs Padres Home Run Prop Bets Today

Over Under
Yastrzemski 0.5 +675 0.5 -1100
Monte Wade Jr 0.5 +875 0.5 -1600
Pauley 0.5 +1100 0.5 -2500
Lee 0.5 +1200 0.5 -3000
Kim 0.5 +1450 0.5 -5000

Giants vs Padres Strikeout Prop Bets Today

Over Under
King 5.5 +105 5.5 -140
Winn 4.5 +130 4.5 -175

Michael King has walked 8 of 25 batters (32%) versus hitters not batting 3-4-5 in the order this season — highest in MLB among starting pitchers with at least 2 total IP; League Avg: 8% — first Percentile.

Opponents have a swing rate of just 25% (29/116) against Michael King in non-two strike counts this season — lowest in MLB among starting pitchers with at least 2 total IP; League Avg: 43% — first Percentile.

Opponents had a miss rate of just 20% (23/113) against Michael King on the first pitch of at-bats in the 2023 season — 10th lowest among qualified RPs in MLB*; League Avg: 30% — 10th Percentile.

Right-handed hitters have a swing rate of just 42% (658/1,572) against Michael King since the 2022 season — 4th lowest among qualified RPs in MLB*; League Avg: 48% — fourth Percentile.

Giants Starting Pitcher Stats & Trends

Keaton Winn has thrown his off-speed pitches for a strike 77% (44/57) of the time this season — highest in MLB among starting pitchers with at least 2 total IP; League Avg: 61% — 100th Percentile.

Keaton Winn has located his pitches away 56% of the time (50/89) this season — 13th highest in MLB among starting pitchers with at least 2 total IP; League Avg: 46% — 91st Percentile.

Keaton Winn has thrown off-speed pitches 64% of the time (57/89) this season — 6th highest in MLB among starting pitchers with at least 2 total NonFB; League Avg: 45% — 96th Percentile.

Opponents have a miss rate of 30% (9/30) against Keaton Winn on pitches in the strike zone this season — 9th best in MLB among starting pitchers with at least 2 total IP; League Avg: 19% — 93rd Percentile.

Padres Keys to the Game vs. the Giants

The Padres were just 2-13 (.133) after a win as underdogs in 2023 — lowest in MLB; League Avg: .430.

The Padres are just 3-14 (.176) after a win as underdogs since the 2023 season — lowest in MLB; League Avg: .428.

The Padres are just 3-67 (.043) when trailing entering the 8th inning since the 2023 season — 4th lowest in MLB; League Avg: .100.

The Padres are just 10-36 (.217) when allowing 2 or more home runs since the 2023 season — 5th lowest in MLB; League Avg: .310.

Giants Keys to the Game vs. the Padres

The Giants are 32-34 (.485) after a win as underdogs since the 2022 season — 5th best in MLB; League Avg: .415.

The Giants are 68-1 (.986) when leading entering the 9th inning since the 2023 season — tied for best in MLB; League Avg: .948.

The Giants were 66-1 (.985) when leading entering the 9th inning in 2023 — 2nd best in MLB; League Avg: .949.

The Giants are 23-13 (.639) after a home loss since the 2023 season — 4th best in MLB; League Avg: .508.

Padres hitters are slugging .464 against LHP since last season — 3rd best in MLB; League Avg: .418.

Padres hitters had an OBP of .343 (1,699 PA’s) against LHP in the 2023 season — tied for 3rd best in MLB; League Avg: .323.

The Padres are batting .218 with two-strikes this season — best in MLB; League Avg: .167.

Padres hitters had an OPS of .808 (1,699 PA’s) against LHP in the 2023 season — 3rd best in MLB; League Avg: .742.

The Giants are batting just .062 on pitches out of the zone this season — lowest in MLB; League Avg: .159.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .742.

Giants hitters slugged just .376 against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .419.

Giants hitters have an OPS of just .475 (3,463 PA’s) with two-strikes since last season — 2nd lowest in MLB; League Avg: .522.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

Padres pitchers have walked 13 of 90 batters (14%) when facing the leadoff batter in the inning this season — 4th highest in MLB; League Avg: 9%.

Opponents had a groundball rate of 45% against Padres pitchers in the 2023 season — 3rd highest in MLB; League Avg: 43%.

The Padres allowed 3.74 runs per game (303/81) at home in the 2023 season — best in MLB; League Avg: 4.64.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 50% against Giants pitchers in the 2023 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2022 season — highest in MLB; League Avg: 43%.

Opponents have a groundball batting average of .500 against Giants pitchers with the shift this season — highest in MLB; League Avg: .232.

Giants vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Alex Cobb (San Francisco Giants): Hip, 15-Day IL
  • Cole Waites (San Francisco Giants): Elbow, 60-Day IL
  • Mike Yastrzemski (San Francisco Giants): Personal, Paternity
  • Tristan Beck (San Francisco Giants): Arm, 60-Day IL
  • Wade Meckler (San Francisco Giants): Undisclosed, 7-Day IL
  • Robbie Ray (San Francisco Giants): Elbow, 60-Day IL
  • Sean Hjelle (San Francisco Giants): Elbow, 15-Day IL
  • Luke Jackson (San Francisco Giants): Back, 15-Day IL
  • Wilmer Flores (San Francisco Giants): Shoulder, Day-To-Day
  • Thomas Szapucki (San Francisco Giants): Pectoral, 60-Day IL
  • Scott Alexander (San Francisco Giants): Ribs, 15-Day IL
  • Ethan Small (San Francisco Giants): Oblique, 60-Day IL
  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.