- The Padres are -115 favorites vs the Giants
- Padres vs Giants Over / Under today: 7 Runs
- Padres / Giants TV Channel: NSBA | PDTV
The San Diego Padres (-115) visit Oracle Park to take on the San Francisco Giants (-105) on Wednesday, June 4, 2025. First pitch is scheduled for 9:45pm EDT in San Francisco, CA, CA.
This season, the Padres are 35-24 against the spread (ATS), while the Giants are 27-34 ATS.
Padres vs Giants Starting Pitchers Today:
- Padres starting pitcher: Nick Pivetta 6-2, 2.76 ERA
- Giants starting pitcher: Kyle Harrison 1-1, 2.57 ERA
Padres vs. Giants Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Padres | -1.5 +155 | O 7 +100 | -115 |
| Giants | +1.5 -190 | U 7 -120 | -105 |
Padres vs Giants Prediction for Today’s Game
Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 51.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:
Best Padres Player Prop Bets Today:
- Gavin Sheets has hit the Home Runs Over in 4 of his last 9 away games (+22.20 Units / 247% ROI)
- Luis Arraez has hit the Singles Under in 14 of his last 20 away games (+13.00 Units / 55% ROI)
- Xander Bogaerts has hit the Runs Under in 14 of his last 15 away games (+12.95 Units / 48% ROI)
- Fernando Tatis Jr. has hit the Hits Under in 17 of his last 20 games (+12.65 Units / 31% ROI)
- Fernando Tatis Jr. has hit the Total Bases Under in 16 of his last 20 away games (+11.40 Units / 48% ROI)
And here are some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:
Best Giants Player Prop Best Bets Today:
- Matt Chapman has hit the RBIs Under in 21 of his last 25 games at home (+14.05 Units / 30% ROI)
- Jung Hoo Lee has hit the Home Runs Over in 2 of his last 10 games at home (+13.00 Units / 130% ROI)
- Matt Chapman has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+13.00 Units / 47% ROI)
- Wilmer Flores has hit the Runs Under in 14 of his last 15 games (+12.35 Units / 45% ROI)
- Matt Chapman has hit the Singles Under in 19 of his last 25 games at home (+9.90 Units / 26% ROI)
Padres Best Bets Today:
- The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 17 games (+10.70 Units / 51% ROI)
- The San Diego Padres have hit the Game Total Under in 27 of their last 45 games (+8.00 Units / 16% ROI)
- The San Diego Padres have hit the Team Total Under in 17 of their last 25 away games (+7.90 Units / 27% ROI)
- The San Diego Padres have hit the Moneyline in 8 of their last 11 games (+4.90 Units / 32% ROI)
- The San Diego Padres have covered the Run Line in 11 of their last 17 away games (+2.60 Units / 10% ROI)
Giants Best Bets Today:
- The San Francisco Giants have hit the Team Total Under in 29 of their last 42 games (+15.70 Units / 32% ROI)
- The San Francisco Giants have hit the Game Total Under in 15 of their last 16 games (+13.80 Units / 78% ROI)
- The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 43 games (+9.40 Units / 18% ROI)
- The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 3 of their last 5 games (+1.70 Units / 22% ROI)
- The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 3 of their last 5 games (+0.70 Units / 12% ROI)
Padres Against the Spread (ATS) Record
Against the spread this season, the Padres are 32-27 against the Run Line (+1.85 Units / 2.4% ROI).
- 35-24 when betting on the Moneyline for +4.85 Units / 5.87% ROI
- 24-33 when betting on the total runs Over for -11.8 Units / -18.39% ROI
- 33-24 when betting on the total runs Under for +6.15 Units / 9.34% ROI
Giants Against the Spread (ATS) Record
Against the spread this season, the Giants are 27-34 against the Run Line (-5.1 Units / -6.78% ROI).
- 33-28 when betting on the Moneyline for -2.45 Units / -2.88% ROI
- 27-33 when betting on the total runs Over for -9.2 Units / -13.86% ROI
- 33-27 when betting on the total runs Under for +2.75 Units / 4.05% ROI
Giants vs Padres Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Matt Chapman (SF) | 0.5 +375 | 0.5 -525 |
| Manny Machado (SD) | 0.5 +475 | 0.5 -700 |
| Heliot Ramos (SF) | 0.5 +475 | 0.5 -650 |
| Fernando Tatis Jr. (SD) | 0.5 +550 | 0.5 -800 |
| Jackson Merrill (SD) | 0.5 +575 | 0.5 -900 |
Giants vs Padres Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Fernando Tatis Jr. (SD) | 0.5 -250 | 0.5 +190 |
| Manny Machado (SD) | 0.5 -235 | 0.5 +175 |
| Jung-hoo Lee (SF) | 0.5 -225 | 0.5 +170 |
| Heliot Ramos (SF) | 0.5 -225 | 0.5 +175 |
| Jose Iglesias (SD) | 0.5 -210 | 0.5 +160 |
Giants vs Padres RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Manny Machado (SD) | 0.5 +150 | 0.5 -200 |
| Jackson Merrill (SD) | 0.5 +150 | 0.5 -200 |
| Matt Chapman (SF) | 0.5 +175 | 0.5 -225 |
| Luis Arraez (SD) | 0.5 +195 | 0.5 -250 |
| Fernando Tatis Jr. (SD) | 0.5 +210 | 0.5 -285 |
Giants vs Padres Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Kyle Harrison (SF) | 4.5 +115 | 4.5 -150 |
| Nick Pivetta (SD) | 6.5 +115 | 6.5 -155 |
Padres Starting Pitcher Stats & Trends
Nick Pivetta has allowed an OPS of just .196 (130 PA’s) with two-strikes this season — best among qualified SPs in MLB; League Avg: .475 — 100th Percentile.
Nick Pivetta has allowed an OBP of just .115 (130 PA’s) with two-strikes this season — best among qualified SPs in MLB; League Avg: .231 — 100th Percentile.
Nick Pivetta has allowed a slugging percentage of just .081 (10 Total Bases / 124 ABs) with two-strikes this season — best among qualified SPs in MLB; League Avg: .244 — 100th Percentile.
Opponents are hitting just .069 (4-for-58) against Nick Pivetta’s elevated fastball this season — best among qualified SPs in MLB; League Avg: .216 — 100th Percentile.
Giants Starting Pitcher Stats & Trends
Right-handed hitters have a chase rate of just 22% (201/896) against Kyle Harrison since last season — lowest in MLB among starting pitchers with at least 88 total IP; League Avg: 30% — 0 Percentile.
Hitters swung at 34% of Kyle Harrison’s breaking pitches (159/470) in the 2024 season — 2nd lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 46% — first Percentile.
Right-handed hitters had a chase rate of just 23% (188/836) against Kyle Harrison in the 2024 season — 2nd lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 30% — first Percentile.
Right-handed hitters have a chase rate of just 23% (259/1,103) against Kyle Harrison since the 2023 season — lowest in MLB among starting pitchers with at least 152 total IP; League Avg: 30% — 0 Percentile.
Padres Keys to the Game vs. the Giants
The Padres are 7-16 (.304) when trailing entering the 7th inning this season — 2nd best in MLB; League Avg: .133.
The Padres are 16-78 (.170) when trailing entering the 8th inning since last season — 2nd best in MLB; League Avg: .098.
The Padres are 20-71 (.220) when trailing entering the 7th inning since last season — 3rd best in MLB; League Avg: .141.
The Padres are 31-9 (.775) when allowing 4 or fewer runs this season — 5th best in MLB; League Avg: .703.
Giants Keys to the Game vs. the Padres
The Giants are 18-2 (.900) when scoring 5 or more runs this season — 5th best in MLB; League Avg: .814.
The Giants are 4-21 (.160) when trailing entering the 8th inning this season — 5th best in MLB; League Avg: .095.
The Giants are 26-159 (.141) when trailing entering the 8th inning since the 2023 season — 5th best in MLB; League Avg: .099.
The Giants were just 20-24 (.455) vs bottom 10 scoring offenses in the 2024 season They play the Reds (16th best runs scored) today.
Padres Hitting Stats & Trends
Padres hitters have struck out in just 18% of it’s PA’s against RHP since last season — best in MLB; League Avg: 22%.
Padres hitters struck out just 799 times in 4,486 PA’s (18%) against RHP in the 2024 season — best in MLB; League Avg: 23%.
Padres hitters have chased 43% of pitches out of the zone with two-strikes this season — highest in MLB; League Avg: 38%.
Padres hitters have a swing rate of 63% with two-strikes since last season — highest in MLB; League Avg: 60%.
Giants Hitting Stats & Trends
Giants hitters are slugging just .140 on the first pitch of at-bats over the last 14 days — lowest in MLB; League Avg: .570.
The Giants batted just .151 with two-strikes in the 2023 season — 2nd lowest in MLB; League Avg: .172.
Giants hitters slugged just .376 against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .419.
Giants hitters had an OPS of just .475 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .523.
Padres Pitching Stats & Trends
Opponents have a miss rate of 27% against Padres pitchers since the 2023 season — tied for 4th best in MLB; League Avg: 25%.
Padres pitchers had a strikeout rate of 24% in the 2024 season — 5th best in MLB; League Avg: 23%.
The Padres pitchers have allowed their opponents to score first in just 37% of their games at home this season — 2nd lowest in MLB; League Avg: 55%.
Padres pitchers have a strikeout rate of 45% with two-strikes since last season — 4th best in MLB; League Avg: 42%.
Giants Pitching Stats & Trends
Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.
Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.
Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.
Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.
More MLB Reading:
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