Pirates vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, May 26

Arizona Diamondbacks designated hitter Lourdes Gurriel Jr. bats during the third inning of a baseball game, Saturday, June 10, 2023, in Detroit.
(AP Photo/Carlos Osorio)
  • The Diamondbacks are -185 favorites vs the Pirates
  • Pirates vs Diamondbacks Over / Under today: 9 Runs
  • Pirates / Diamondbacks TV Channel: DBTV | SNPT | MLBN

The Pittsburgh Pirates (+155) visit Chase Field to take on the Arizona Diamondbacks (-185) on Monday, May 26, 2025. First pitch is scheduled for 8:10pm EDT in Phoenix, AZ, AZ.

This season, the Pirates are 19-35 against the spread (ATS), while the Diamondbacks are 24-29 ATS.

Pirates vs Diamondbacks Starting Pitchers Today:

  • Pirates starting pitcher: Andrew Heaney 3-3, 2.93 ERA
  • Diamondbacks starting pitcher: Ryne Nelson 1-1, 4.55 ERA

Pirates vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Pirates+1.5 -130O 9 +100+155
Diamondbacks -1.5 +105U 9 -120-185

Pirates vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Monday‘s MLB game with 61.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Pirates players for Monday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

  • Bryan Reynolds has hit the Runs Under in 17 of his last 20 away games (+11.70 Units / 32% ROI)
  • Bryan Reynolds has hit the Hits Runs and RBIs Under in 18 of his last 25 away games (+10.25 Units / 32% ROI)
  • Isiah Kiner-Falefa has hit the Home Runs Over in 1 of his last 6 away games (+10.00 Units / 167% ROI)
  • Andrew McCutchen has hit the Singles Over in 11 of his last 15 games (+8.80 Units / 58% ROI)
  • Isiah Kiner-Falefa has hit the Total Bases Over in his last 8 games (+8.45 Units / 62% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Monday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

  • Gabriel Moreno has hit the Home Runs Over in 2 of his last 5 games (+14.00 Units / 280% ROI)
  • Geraldo Perdomo has hit the Hits Over in 19 of his last 25 games (+11.25 Units / 29% ROI)
  • Geraldo Perdomo has hit the Total Bases Over in 19 of his last 25 games (+10.70 Units / 28% ROI)
  • Ketel Marte has hit the Runs Over in 12 of his last 15 games (+9.35 Units / 54% ROI)
  • Randal Grichuk has hit the RBIs Under in his last 7 games at home (+7.00 Units / 49% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 34 of their last 53 games (+12.80 Units / 20% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 26 of their last 42 games (+11.60 Units / 25% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 21 games (+10.60 Units / 42% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 10 of their last 16 games (+3.00 Units / 15% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 4 of their last 6 games (+2.30 Units / 36% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 25 of their last 37 games (+13.10 Units / 29% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 21 of their last 37 games (+10.40 Units / 20% ROI)
  • The Arizona Diamondbacks have hit the Game Total Under in 16 of their last 24 games (+8.35 Units / 32% ROI)
  • The Arizona Diamondbacks have hit the Team Total Over in 11 of their last 18 games at home (+3.00 Units / 14% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 4 of their last 5 games (+2.90 Units / 47% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 22-32 against the Run Line (-16.5 Units / -23.64% ROI).

  • 19-35 when betting on the Moneyline for -13.85 Units / -23.12% ROI
  • 20-31 when betting on the total runs Over for -13.75 Units / -23.27% ROI
  • 31-20 when betting on the total runs Under for +9.05 Units / 15.16% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 24-29 against the Run Line (-9.81 Units / -14.15% ROI).

  • 26-27 when betting on the Moneyline for -6.1 Units / -8.68% ROI
  • 23-26 when betting on the total runs Over for -5.8 Units / -9.93% ROI
  • 26-23 when betting on the total runs Under for +0.5 Units / 0.86% ROI

Diamondbacks vs Pirates Home Run Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +270 0.5 -350
Oneil Cruz (PIT) 0.5 +300 0.5 -400
Eugenio Suarez (ARI) 0.5 +375 0.5 -525
Randal Grichuk (ARI) 0.5 +450 0.5 -625
Andrew McCutchen (PIT) 0.5 +475 0.5 -700

Diamondbacks vs Pirates Total Hits Prop Bets Today

Over Under
Corbin Carroll (ARI) 0.5 -250 0.5 +190
Gabriel Moreno (ARI) 0.5 -250 0.5 +185
Oneil Cruz (PIT) 0.5 -235 0.5 +180
Randal Grichuk (ARI) 0.5 -220 0.5 +160
Josh Naylor (ARI) 0.5 -220 0.5 +165

Diamondbacks vs Pirates RBI Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +120 0.5 -155
Lourdes Gurriel Jr (ARI) 0.5 +125 0.5 -160
Eugenio Suarez (ARI) 0.5 +140 0.5 -185
Oneil Cruz (PIT) 0.5 +145 0.5 -190
Andrew McCutchen (PIT) 0.5 +165 0.5 -220

Diamondbacks vs Pirates Strikeout Prop Bets Today

Over Under
Andrew Heaney (PIT) 3.5 -118 3.5 -110
Ryne Nelson (ARI) 4.5 +100 4.5 -130

Opponents are hitting just .125 (5-for-40) against Andrew Heaney’s elevated fastball this season — 5th best among qualified SPs in MLB; League Avg: .218 — 93rd Percentile.

Andrew Heaney has allowed a slugging percentage of .475 (164 Total Bases / 345 ABs) when going through the lineup the second time in a game since last season — 3rd highest among qualified SPs in MLB; League Avg: .381 — sixth Percentile.

Opponents are hitting just .115 (6-for-52) against Andrew Heaney when facing the leadoff batter in the inning this season — 2nd best among qualified SPs in MLB; League Avg: .246 — 98th Percentile.

64% of Andrew Heaney’s strikeouts are in the zone this season — 7th highest among qualified SPs in MLB; League Avg: 49% — 92nd Percentile.

Diamondbacks Starting Pitcher Stats & Trends

Ryne Nelson had an ERA of 8.25 (55.2 IP) at home in 2023 — tied for highest in MLB among starting pitchers with at least 64 total IP; League Avg: 4.14 — first Percentile.

Left-handed hitters have a chase rate of just 17% (20/120) against Ryne Nelson this season — 3rd lowest among qualified RPs in MLB*; League Avg: 28% — second Percentile.

Right-handed hitters have a line drive rate of 32% (90/280) against Ryne Nelson since last season — highest in MLB among starting pitchers with at least 85 total IP; League Avg: 24% — 0 Percentile.

Left-handed hitters have a swing rate of just 38% (91/240) against Ryne Nelson this season — 2nd lowest among NL Relievers; League Avg: 47% — second Percentile.

Pirates Keys to the Game vs. the Diamondbacks

The Pirates are just 9-62 (.127) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .255.

The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.

The Pirates are just 8-46 (.148) when allowing 2 or more home runs since last season — lowest in MLB; League Avg: .291.

The Pirates were just 10-32 (.238) when their opponents score in the first inning in the 2024 season — 3rd lowest in MLB; League Avg: .359.

Diamondbacks Keys to the Game vs. the Pirates

The Diamondbacks are 154-40 (.790) when allowing 4 or fewer runs since the 2023 season — 3rd best in MLB; League Avg: .724.

The Diamondbacks are just 19-6 (.760) when leading entering the 7th inning this season — 3rd lowest in MLB; League Avg: .868.

The Diamondbacks are 58-50 (.537) on the road since last season — 5th best in MLB; League Avg: .469.

The Diamondbacks are 17-70 (.193) when trailing entering the 7th inning since last season — tied for 4th best in MLB; League Avg: .140.

The Pirates are batting just .206 on the road this season — 2nd lowest in MLB; League Avg: .240.

Pirates hitters are slugging just .507 on the first pitch of at-bats since the 2023 season — lowest in MLB; League Avg: .577.

Pirates hitters have an OPS of just .588 (922 PA’s) on the road this season — 2nd lowest in MLB; League Avg: .697.

Pirates hitters have an OPS of just .595 (630 PA’s) in innings 7-9 this season — 2nd lowest in MLB; League Avg: .703.

Diamondbacks hitters had an OBP of .337 (6,284 PA’s) in the 2024 season — best in MLB; League Avg: .312.

Diamondbacks hitters had an OBP of .347 (3,080 PA’s) at home in the 2024 season — best in MLB; League Avg: .315.

The Diamondbacks batted .276 at home in the 2024 season — best in MLB; League Avg: .244.

Diamondbacks hitters have an OBP of .330 (10,192 PA’s) against RHP since the 2023 season — 2nd best in MLB; League Avg: .316.

Batters facing the Pirates pitchers have struck out in the zone 52% of the time since last season — 3rd highest in MLB; League Avg: 50%. since last season — 3rd highest in MLB; League Avg: 50%.

Pirates pitchers have won only 8% of games in which they have allowed their opponent to score in three different innings this season — 2nd lowest in MLB; League Avg: 28%.

Pirates pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — 2nd best in MLB; League Avg: 8%.

The Pirates have won just 8% of games in which their opponents scored first this season — lowest in MLB; League Avg: 33%.

Opponents had a miss rate of just 24% against Diamondbacks pitchers in the 2024 season — tied for 4th lowest in MLB; League Avg: 25%.

The Diamondbacks pitchers have allowed division opponents to score first in just 35% of their games since last season — 2nd lowest in MLB; League Avg: 50%.

The Diamondbacks pitchers have allowed their opponents to score first in just 34% of their games on the road since last season — lowest in MLB; League Avg: 44%.

Diamondbacks pitchers have a in-zone of just 48% this season — 2nd lowest in MLB; League Avg: 51%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.