Pirates vs Padres Prediction, Odds & Player Prop Bets Today – MLB, May 31

(AP Photo/Derrick Tuskan)
  • The Padres are -220 favorites vs the Pirates
  • Pirates vs Padres Over / Under today: 7.5 Runs
  • Pirates / Padres TV Channel: SNPT | PDTV | KFMB

The Pittsburgh Pirates (+180) visit Petco Park to take on the San Diego Padres (-220) on Saturday, May 31, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA.

This season, the Pirates are 21-37 against the spread (ATS), while the Padres are 29-26 ATS.

Pirates vs Padres Starting Pitchers Today:

  • Pirates starting pitcher: Bailey Falter 3-3, 3.47 ERA
  • Padres starting pitcher: Dylan Cease 1-3, 4.63 ERA

Pirates vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Pirates+1.5 -120O 7.5 +100+180
Padres -1.5 +100U 7.5 -120-220

Pirates vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Saturday‘s MLB game with 64.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Pirates vs Padres and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Pirates players for Saturday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

  • Bryan Reynolds has hit the Runs Under in 21 of his last 25 away games (+13.80 Units / 30% ROI)
  • Isiah Kiner-Falefa has hit the Total Bases Over in 19 of his last 25 away games (+10.20 Units / 25% ROI)
  • Oneil Cruz has hit the Singles Under in 18 of his last 25 games (+8.50 Units / 23% ROI)
  • Bryan Reynolds has hit the Home Runs Over in 2 of his last 6 away games (+8.20 Units / 137% ROI)
  • Isiah Kiner-Falefa has hit the Hits Over in 19 of his last 25 away games (+7.50 Units / 17% ROI)

And here are some favorite MLB player prop bets for Padres players for Saturday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Gavin Sheets has hit the Home Runs Over in 4 of his last 8 games (+23.10 Units / 289% ROI)
  • Manny Machado has hit the Hits Runs and RBIs Over in 20 of his last 25 games (+14.00 Units / 44% ROI)
  • Fernando Tatis Jr. has hit the Hits Under in 19 of his last 25 games (+11.20 Units / 25% ROI)
  • Dylan Cease has hit the Earned Runs Over in 15 of his last 20 games (+10.45 Units / 43% ROI)
  • Manny Machado has hit the Runs Over in 17 of his last 25 games (+10.30 Units / 37% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 25 games (+12.60 Units / 42% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 36 of their last 57 games (+12.50 Units / 19% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 28 of their last 46 games (+11.45 Units / 22% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 13 of their last 20 games (+4.90 Units / 19% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 6 of their last 10 games (+3.65 Units / 35% ROI)
  • The San Diego Padres have covered the Run Line in 16 of their last 26 games at home (+8.40 Units / 29% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 17 of their last 26 games at home (+7.00 Units / 23% ROI)
  • The San Diego Padres have hit the Team Total Over in 18 of their last 28 games at home (+7.00 Units / 21% ROI)
  • The San Diego Padres have hit the Game Total Under in 17 of their last 26 games at home (+6.85 Units / 24% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 13 games (+6.70 Units / 43% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 25-33 against the Run Line (-14.6 Units / -19.4% ROI).

  • 21-37 when betting on the Moneyline for -12.5 Units / -19.56% ROI
  • 22-33 when betting on the total runs Over for -13.95 Units / -21.95% ROI
  • 33-22 when betting on the total runs Under for +8.9 Units / 13.9% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 29-26 against the Run Line (-0.45 Units / -0.63% ROI).

  • 32-23 when betting on the Moneyline for +3.2 Units / 4.16% ROI
  • 23-30 when betting on the total runs Over for -9.45 Units / -15.86% ROI
  • 30-23 when betting on the total runs Under for +4.15 Units / 6.74% ROI

Padres vs Pirates Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +275 0.5 -350
Fernando Tatis Jr. (SD) 0.5 +300 0.5 -375
Oneil Cruz (PIT) 0.5 +400 0.5 -525
Jackson Merrill (SD) 0.5 +425 0.5 -625
Bryan Reynolds (PIT) 0.5 +600 0.5 -900

Padres vs Pirates Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -275 0.5 +200
Xander Bogaerts (SD) 0.5 -210 0.5 +160
Bryan Reynolds (PIT) 0.5 -175 0.5 +135
Oneil Cruz (PIT) 0.5 -155 0.5 +115
Gavin Sheets (SD) 0.5 -150 0.5 +115

Padres vs Pirates RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +120 0.5 -160
Jackson Merrill (SD) 0.5 +145 0.5 -190
Fernando Tatis Jr. (SD) 0.5 +155 0.5 -200
Xander Bogaerts (SD) 0.5 +180 0.5 -235
Gavin Sheets (SD) 0.5 +195 0.5 -275

Padres vs Pirates Strikeout Prop Bets Today

Over Under
Bailey Falter (PIT) 3.5 +105 3.5 -135
Dylan Cease (SD) 7.5 +125 7.5 -160

Bailey Falter has thrown inside pitches 49% of the time (116/238) on the first pitch of at-bats this season — highest among qualified SPs in MLB; League Avg: 29% — 100th Percentile.

Bailey Falter has a strikeout rate of just 10% (10 SO in 97 PAs) when going through the lineup the second time in a game this season — 2nd lowest among qualified SPs in MLB; League Avg: 22% — second Percentile.

Bailey Falter has thrown inside pitches 49% of the time (116/238) on the first pitch of at-bats this season — highest among among NL Starters; League Avg: 30% — 100th Percentile.

Bailey Falter has thrown inside pitches 46% of the time (303/658) in non-two strike counts this season — highest among among NL Starters; League Avg: 31% — 100th Percentile.

Padres Starting Pitcher Stats & Trends

Dylan Cease has walked 11% of batters when going through the lineup the second time in a game since the 2023 season — highest among qualified SPs in MLB; League Avg: 7% — third Percentile.

Right-handed hitters had a miss rate of 36% (289/799) against Dylan Cease in the 2024 season — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Dylan Cease has thrown his slider 58% of the time (116/200) when he’s behind in the count this season — 2nd highest among qualified SPs in MLB; League Avg: 18% — 98th Percentile.

Dylan Cease threw breaking pitches 55% of the time (1,752/3,188) in the 2024 season — highest among among NL Starters; League Avg: 31% — 100th Percentile.

Pirates Keys to the Game vs. the Padres

The Pirates are just 9-63 (.125) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .254.

The Pirates were just 10-32 (.238) when their opponents score in the first inning in the 2024 season — 3rd lowest in MLB; League Avg: .359.

The Pirates are just 12-43 (.218) when their opponents score in the first inning since last season — 2nd lowest in MLB; League Avg: .363.

The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.

Padres Keys to the Game vs. the Pirates

The Padres are 15-78 (.161) when trailing entering the 8th inning since last season — 3rd best in MLB; League Avg: .099.

The Padres were 48-33 (.593) on the road in the 2024 season — 2nd best in MLB; League Avg: .478.

The Padres are 52-14 (.788) when they’ve hit 2 or more home runs since last season — 5th best in MLB; League Avg: .711.

The Padres are 18-3 (.857) when they’ve had 10 or more hits this season — 4th best in MLB; League Avg: .734.

Opponents have used a defensive shift against the Pirates on 0% of their plate appearances this season — 2nd highest in MLB; League Avg: 0%.. *

Pirates hitters are slugging just .315 on the road this season — 2nd lowest in MLB; League Avg: .388.

Pirates hitters have 11 extra-base hits out of 56 total hits (just 20%) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB; League Avg: 34%.

Pirates hitters have put just 25% of their swings in play in lefty-lefty matchups this season — lowest in MLB; League Avg: 36%.

The Padres batted .275 on the road in the 2024 season — best in MLB; League Avg: .242.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of it’s PA’s since last season — best in MLB; League Avg: 22%.

Padres hitters have struck out in just 18% of it’s PA’s against RHP since last season — best in MLB; League Avg: 22%.

Pirates pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — 2nd best in MLB; League Avg: 8%.

Pirates pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB; League Avg: 22%.

Pirates pitchers have won only 8% of games in which they have allowed their opponent to score in three different innings this season — 2nd lowest in MLB; League Avg: 27%.

Opponents have a miss rate of just 25% against Pirates pitchers since the 2023 season — 5th lowest in MLB; League Avg: 25%.

Opponents have a miss rate of 27% against Padres pitchers since last season — 4th best in MLB; League Avg: 25%.

Padres pitchers had a strikeout rate of 44% with two-strikes in the 2024 season — tied for 4th best in MLB; League Avg: 42%.

The Padres pitchers have allowed an average Exit Velocity of just 88.3 MPH since the 2023 season (9,197 balls in play) — best in MLB; League Avg: 89.0

Opponents had a miss rate of 27% against Padres pitchers in the 2024 season — tied for 4th best in MLB; League Avg: 25%.

More MLB Reading:


Bet now on Pirates vs Padres and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.