Red Sox vs Rays Prediction, Odds & Player Prop Bets Today – MLB, Apr 16

Tampa Bay Rays' Brandon Lowe runs the bases while scoring from first base on a two-run triple by Randy Arozarena off Baltimore Orioles starting pitcher Kyle Bradish in the third inning of a baseball game, Thursday, Sept. 14, 2023, in Baltimore. Rays' Yandy Diaz also scored on the triple.
(AP Photo/Julio Cortez)
  • The Rays are -145 favorites vs the Red Sox
  • Red Sox vs Rays Over / Under today: 9.5 Runs
  • Red Sox / Rays TV Channel: FSUN | NESN

The Boston Red Sox (+120) visit George M. Steinbrenner Field to take on the Tampa Bay Rays (-145) on Wednesday, April 16, 2025. First pitch is scheduled for 7:05pm EDT in Tampa, FL.

This season, the Red Sox are 9-10 against the spread (ATS), while the Rays are 6-11 ATS.

Red Sox vs Rays Starting Pitchers Today:

  • Red Sox starting pitcher: Sean Newcomb 0-2, 4.85 ERA
  • Rays starting pitcher: Zack Littell 0-3, 6.89 ERA

Red Sox vs. Rays Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox+1.5 -170O 9.5 -120+120
Rays -1.5 +140U 9.5 +100-145

Red Sox vs Rays Prediction for Today’s Game

Based on recent trends the model predicts the Rays will win Wednesday‘s MLB game with 54.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Rafael Devers has hit the Hits Under in 18 of his last 25 away games (+19.40 Units / 69% ROI)
  • Rafael Devers has hit the Total Bases Under in 20 of his last 25 away games (+16.15 Units / 49% ROI)
  • Kristian Campbell has hit the Home Runs Over in 3 of his last 10 away games (+14.60 Units / 146% ROI)
  • Rafael Devers has hit the Runs Under in 21 of his last 25 away games (+14.55 Units / 40% ROI)
  • Rafael Devers has hit the Hits Runs and RBIs Under in 20 of his last 25 away games (+14.20 Units / 48% ROI)

And here are some favorite MLB player prop bets for Rays players for Wednesday‘s game, looking at profitable historical betting trends:

Best Rays Player Prop Best Bets Today:

  • Junior Caminero has hit the Home Runs Over in 4 of his last 8 games (+14.50 Units / 181% ROI)
  • Junior Caminero has hit the Runs Over in 7 of his last 8 games (+8.20 Units / 102% ROI)
  • Taylor Walls has hit the Singles Over in 6 of his last 8 games (+6.80 Units / 85% ROI)
  • Danny Jansen has hit the Hits Under in 7 of his last 9 games at home (+6.60 Units / 73% ROI)
  • Curtis Mead has hit the Hits Runs and RBIs Under in 11 of his last 15 games (+6.20 Units / 31% ROI)
  • The Boston Red Sox have hit the Team Total Under in 8 of their last 9 games (+6.55 Units / 53% ROI)
  • The Boston Red Sox have hit the Game Total Under in 11 of their last 19 games (+3.45 Units / 16% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 7 of their last 14 games (+3.25 Units / 16% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 43 of their last 83 away games (+0.05 Units / 0% ROI)
  • The Tampa Bay Rays have hit the 1st Five Innings (F5) Team Total Under in 97 of their last 162 games (+27.96 Units / 15% ROI)
  • The Tampa Bay Rays have hit the Game Total Under in 89 of their last 162 games (+17.20 Units / 10% ROI)
  • The Tampa Bay Rays have hit the Team Total Under in 93 of their last 162 games (+16.50 Units / 9% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 9-10 against the Run Line (-0.65 Units / -2.69% ROI).

  • 9-10 when betting on the Moneyline for -4.05 Units / -16.14% ROI
  • 7-11 when betting on the total runs Over for -4.85 Units / -23.32% ROI
  • 11-7 when betting on the total runs Under for +3.45 Units / 16.43% ROI

Rays Against the Spread (ATS) Record

Against the spread this season, the Rays are 6-11 against the Run Line (-5.45 Units / -28.24% ROI).

  • 8-9 when betting on the Moneyline for -3.1 Units / -12.92% ROI
  • 8-8 when betting on the total runs Over for -0.75 Units / -3.94% ROI
  • 8-8 when betting on the total runs Under for -0.4 Units / -2.18% ROI

Rays vs Red Sox Home Run Prop Bets Today

Over Under
Rafael Devers (BOS) 0.5 +270 0.5 -350
Wilyer Abreu (BOS) 0.5 +275 0.5 -350
Christopher Morel (TB) 0.5 +360 0.5 -500
Jarren Duran (BOS) 0.5 +450 0.5 -650
Yandy Diaz (TB) 0.5 +475 0.5 -700

Rays vs Red Sox Total Hits Prop Bets Today

Over Under
Junior Caminero (TB) 0.5 -225 0.5 +170
Curtis Mead (TB) 0.5 -220 0.5 +160
Trevor Story (BOS) 0.5 -210 0.5 +160
Rafael Devers (BOS) 0.5 -200 0.5 +150
Jake Mangum (TB) 0.5 -200 0.5 +150

Rays vs Red Sox RBI Prop Bets Today

Over Under
Wilyer Abreu (BOS) 0.5 +145 0.5 -190
Rafael Devers (BOS) 0.5 +150 0.5 -200
Christopher Morel (TB) 0.5 +150 0.5 -200
Yandy Diaz (TB) 0.5 +160 0.5 -210
Danny Jansen (TB) 0.5 +170 0.5 -225

Rays vs Red Sox Strikeout Prop Bets Today

Over Under
Zack Littell (TB) 5.5 +120 5.5 -155
Sean Newcomb (BOS) 4.5 +120 4.5 -160

Sean Newcomb has allowed a BABIP of .548 against right-handed batters this season — highest in MLB among starting pitchers with at least 6 total IP; League Avg: .278 — 0 Percentile.

Opponents are hitting .435 (10-for-23) against Sean Newcomb when going through the lineup the first time in a game this season — 2nd highest in MLB among starting pitchers with at least 6 total IP; League Avg: .234 — first Percentile.

Sean Newcomb has allowed an OBP of .452 (62 PA’s) this season — 4th highest in MLB among starting pitchers with at least 6 total IP; League Avg: .308 — second Percentile.

Sean Newcomb has allowed an OBP of .469 (49 PA’s) against right-handed batters this season — 3rd highest in MLB among starting pitchers with at least 6 total IP; League Avg: .303 — second Percentile.

Rays Starting Pitcher Stats & Trends

Zack Littell has a strike rate of 72% (179/247) this season — 2nd highest among qualified SPs in MLB; League Avg: 64% — 98th Percentile.

Zack Littell has a strike rate of 72% (179/247) this season — highest among among AL Starters; League Avg: 65% — 100th Percentile.

Zack Littell has walked 8 of 395 batters (2%) when going through the lineup the second time in a game since the 2023 season — best in MLB among starting pitchers with at least 135 total IP; League Avg: 7% — 100th Percentile.

Zack Littell threw breaking pitches away 88% of the time (83/94) in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 49% — 100th Percentile.

Red Sox Keys to the Game vs. the Rays

The Red Sox are just 14-137 (.093) when trailing entering the 7th inning since the 2023 season — 3rd lowest in MLB; League Avg: .140.

The Red Sox are just 0-8 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .117.

The Red Sox were just 17-33 (.340) vs top 10 scoring offenses in the 2024 season They play the Blue Jays (23rd best runs scored) today.

The Red Sox were just 38-43 (.469) at home in the 2024 season — tied for 5th lowest in MLB; League Avg: .521.

Rays Keys to the Game vs. the Red Sox

The Rays are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Rays are 12-133 (.082) when trailing entering the 9th inning since the 2023 season — 2nd best in MLB; League Avg: .049.

The Rays are just 24-35 (.407) vs the top 10 runs allowed teams since last season They play the Red Sox (23rd best runs allowed) today.

The Rays are 88-22 (.800) when they’ve had 10 or more hits since the 2023 season — 5th best in MLB; League Avg: .741.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters have 546 strikeouts in 1,966 PA’s (28%) against LHP since last season — highest in MLB; League Avg: 23%.

Red Sox hitters put just 32% of their swings in play against LHP in the 2024 season — lowest in MLB; League Avg: 37%.

Red Sox hitters are averaging 4.37 pitches per plate appearance against LHP this season — highest in MLB; League Avg: 3.92.

Rays hitters have an OPS of just .670 (5,114 PA’s) against RHP since last season — 3rd lowest in MLB; League Avg: .711.

Rays hitters slugged just .358 against RHP in the 2024 season — 2nd lowest in MLB; League Avg: .400.

Rays hitters had an OPS of .774 (4,837 PA’s) against RHP in the 2023 season — 4th best in MLB; League Avg: .732.

Rays hitters are slugging .453 against RHP this season — 5th best in MLB; League Avg: .389.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

Opponents have a groundball batting average of .303 against Red Sox pitchers this season — highest in MLB; League Avg: .242.

Opponents have a miss rate of just 24% against Red Sox pitchers since last season — 2nd lowest in MLB; League Avg: 25%.

Red Sox pitchers walked 98 of 1,456 batters (7%) when facing the leadoff batter in the inning in the 2024 season — tied for 5th best in MLB; League Avg: 7%.

Rays pitchers have walked 39 of 618 batters (6%) this season — best in MLB; League Avg: 9%.

Opponents have a swing rate of 52% against the Rays pitchers this season — highest in MLB; League Avg: 47%.

Rays pitchers walked 439 of 5,994 batters (7%) in 2023 — tied for 3rd best in MLB; League Avg: 9%.

Opponents had a groundball rate of just 40% against Rays pitchers in the 2024 season — 2nd lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.