Red Sox vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, Apr 11

Chicago White Sox's Andrew Benintendi adjusts his helmet while standing on third base during the first inning of a spring training baseball game against the Texas Rangers in Phoenix, Monday, Feb. 26, 2024.
(AP Photo/Ashley Landis)
  • The Red Sox are -160 favorites vs the White Sox
  • Red Sox vs White Sox Over / Under today: 8 Runs
  • Red Sox / White Sox TV Channel: NESN | CHS+

The Boston Red Sox (-160) visit Rate Field to take on the Chicago White Sox (+135) on Friday, April 11, 2025. First pitch is scheduled for 7:40pm EDT in Chicago, IL.

This season, the Red Sox are 7-7 against the spread (ATS), while the White Sox are 7-5 ATS.

Red Sox vs White Sox Starting Pitchers Today:

  • Red Sox starting pitcher: Sean Newcomb 0-1, 5.20 ERA
  • White Sox starting pitcher: Davis Martin 0-1, 5.73 ERA

Red Sox vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox-1.5 +105O 8 -115-160
White Sox +1.5 -130U 8 -105+135

Red Sox vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Friday‘s MLB game with 60.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Friday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Rafael Devers has hit the Hits Under in 14 of his last 20 away games (+14.65 Units / 64% ROI)
  • Rafael Devers has hit the Total Bases Under in 16 of his last 20 away games (+12.40 Units / 47% ROI)
  • Rafael Devers has hit the Runs Under in 17 of his last 20 away games (+12.00 Units / 41% ROI)
  • Kristian Campbell has hit the Home Runs Over in 2 of his last 5 away games (+11.60 Units / 232% ROI)
  • Rafael Devers has hit the Hits Runs and RBIs Under in 16 of his last 20 away games (+11.50 Units / 49% ROI)

And here are some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Michael A. Taylor has hit the Home Runs Over in 2 of his last 4 games at home (+12.70 Units / 317% ROI)
  • Miguel Vargas has hit the Runs Under in his last 8 games (+8.00 Units / 41% ROI)
  • Luis Robert has hit the Hits Runs and RBIs Under in his last 7 games (+7.40 Units / 79% ROI)
  • Omar Narvaez has hit the Hits Under in 7 of his last 8 games (+6.25 Units / 75% ROI)
  • Omar Narvaez has hit the Total Bases Under in 7 of his last 8 games (+6.20 Units / 75% ROI)
  • The Boston Red Sox have hit the Game Total Under in 9 of their last 14 games (+4.55 Units / 29% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 9 games (+3.65 Units / 29% ROI)
  • The Boston Red Sox have hit the Team Total Over in 44 of their last 78 away games (+3.45 Units / 4% ROI)
  • The Boston Red Sox have hit the Moneyline in 6 of their last 9 games (+1.30 Units / 11% ROI)
  • The Boston Red Sox have covered the Run Line in 7 of their last 14 games (+1.25 Units / 7% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 44 of their last 78 games at home (+6.20 Units / 7% ROI)
  • The Chicago White Sox have hit the Team Total Under in their last 5 games (+5.20 Units / 87% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 5 of their last 6 games at home (+3.95 Units / 55% ROI)
  • The Chicago White Sox have hit the Game Total Under in 4 of their last 5 games (+2.80 Units / 49% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 3 of their last 6 games at home (+2.80 Units / 46% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 7-7 against the Run Line (+1.25 Units / 7.29% ROI).

  • 7-7 when betting on the Moneyline for -1.9 Units / -10.86% ROI
  • 4-9 when betting on the total runs Over for -5.65 Units / -37.42% ROI
  • 9-4 when betting on the total runs Under for +4.55 Units / 28.98% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 7-5 against the Run Line (+1.3 Units / 8.72% ROI).

  • 2-10 when betting on the Moneyline for -7 Units / -58.33% ROI
  • 5-6 when betting on the total runs Over for -1.45 Units / -11.11% ROI
  • 6-5 when betting on the total runs Under for +0.45 Units / 3.37% ROI

White Sox vs Red Sox Home Run Prop Bets Today

Over Under
Rafael Devers (BOS) 0.5 +350 0.5 -450
Alex Bregman (BOS) 0.5 +450 0.5 -625
Wilyer Abreu (BOS) 0.5 +450 0.5 -650
Kristian Campbell (BOS) 0.5 +525 0.5 -750
Jarren Duran (BOS) 0.5 +550 0.5 -800

White Sox vs Red Sox Total Hits Prop Bets Today

Over Under
Alex Bregman (BOS) 0.5 -235 0.5 +175
Andrew Vaughn (CWS) 0.5 -220 0.5 +160
Rafael Devers (BOS) 0.5 -210 0.5 +155
Lenyn Sosa (CWS) 0.5 -190 0.5 +145
Luis Robert (CWS) 0.5 -190 0.5 +145

White Sox vs Red Sox RBI Prop Bets Today

Over Under
Alex Bregman (BOS) 0.5 +135 0.5 -185
Rafael Devers (BOS) 0.5 +155 0.5 -200
Ceddanne Rafaela (BOS) 0.5 +190 0.5 -250
Wilyer Abreu (BOS) 0.5 +190 0.5 -250
Kristian Campbell (BOS) 0.5 +190 0.5 -250

White Sox vs Red Sox Strikeout Prop Bets Today

Over Under
Sean Newcomb (BOS) 4.5 -155 4.5 +120
Davis Martin (CWS) 4.5 +115 4.5 -150

Sean Newcomb has allowed an OBP of .455 (22 PA’s) with two-strikes this season — 3rd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .244 — second Percentile.

Sean Newcomb has allowed an OBP of .488 (41 PA’s) this season — 2nd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .309 — first Percentile.

Sean Newcomb has allowed a BABIP of .579 against right-handed batters this season — 2nd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .276 — first Percentile.

Opponents are hitting .500 (8-for-16) against Sean Newcomb when going through the lineup the first time in a game this season — tied for 3rd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .240 — third Percentile.

White Sox Starting Pitcher Stats & Trends

Davis Martin has not struck out any hitters in 18 PA’s when going through the lineup the first time in a game this season — lowest in MLB among starting pitchers with at least 4 total IP; League Avg: 23% — 0 Percentile.

Davis Martin has a strikeout rate of just 20% (4 SO in 20 PAs) with two-strikes this season — tied for 3rd lowest in MLB among starting pitchers with at least 4 total IP; League Avg: 42% — third Percentile.

Davis Martin has a strikeout rate of just 12% (2 SO in 17 PAs) on low non-fastballs this season — tied for 4th lowest in MLB among starting pitchers with at least 4 total IP; League Avg: 35% — fifth Percentile.

Opponents have a miss rate of just 15% (13/88) against Davis Martin this season — 5th lowest in MLB among starting pitchers with at least 4 total IP; League Avg: 25% — third Percentile.

Red Sox Keys to the Game vs. the White Sox

The Red Sox were just 18-69 (.207) when they scored 4 or fewer runs in the 2024 season — 4th lowest in MLB; League Avg: .276.

The Red Sox are just 4-148 (.026) when trailing entering the 9th inning since the 2023 season — tied for 4th lowest in MLB; League Avg: .050.

The Red Sox were just 38-43 (.469) at home in the 2024 season — tied for 5th lowest in MLB; League Avg: .521.

The Red Sox are just 5-64 (.072) when trailing entering the 7th inning since last season — 3rd lowest in MLB; League Avg: .143.

White Sox Keys to the Game vs. the Red Sox

The White Sox were just 26-95 (.215) after a loss in the 2024 season — lowest in MLB; League Avg: .504.

The White Sox are just 81-38 (.681) when leading entering the 7th inning since the 2023 season — lowest in MLB; League Avg: .858.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 9-41 (.180) vs top 10 scoring offenses since last season They play the Red Sox (ninth best runs scored) today.

Red Sox hitters have 537 strikeouts in 1,933 PA’s (28%) against LHP since last season — highest in MLB; League Avg: 23%.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters have put just 32% of their swings in play against LHP since last season — lowest in MLB; League Avg: 36%.

Red Sox hitters are averaging 4.34 pitches per plate appearance against LHP this season — 2nd highest in MLB; League Avg: 3.91.

White Sox hitters have an OPS of just .643 (9,305 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .721.

White Sox hitters have an OBP of just .282 (9,305 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .315.

White Sox hitters had an OBP of just .278 (5,869 PA’s) in the 2024 season — lowest in MLB; League Avg: .312.

The White Sox had a winning percentage of just 28% at home last season — lowest in MLB; League Avg: 52%.

Red Sox pitchers have a strikeout rate of just 19% with runners in scoring position since last season — 3rd lowest in MLB; League Avg: 22%.

Red Sox pitchers have a strikeout rate of just 39% with two-strikes this season — 4th lowest in MLB; League Avg: 43%.

Opponents have a miss rate of just 24% against Red Sox pitchers since last season — 2nd lowest in MLB; League Avg: 25%.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

In games when their opponents have scored three or more runs in an inning, the White Sox have won just just 10% of the time since the 2023 season — lowest in MLB; League Avg: 24%.

The White Sox won just 11% of games in which their opponents scored first last season — lowest in MLB; League Avg: 31%.

The White Sox won just 13% of home games in which their opponents scored first last season — lowest in MLB; League Avg: 35%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.